KR20230013259A - 자성 나노 입자를 사용하는 분석물(들)의 검출 및 정량화 - Google Patents

자성 나노 입자를 사용하는 분석물(들)의 검출 및 정량화 Download PDF

Info

Publication number
KR20230013259A
KR20230013259A KR1020227044248A KR20227044248A KR20230013259A KR 20230013259 A KR20230013259 A KR 20230013259A KR 1020227044248 A KR1020227044248 A KR 1020227044248A KR 20227044248 A KR20227044248 A KR 20227044248A KR 20230013259 A KR20230013259 A KR 20230013259A
Authority
KR
South Korea
Prior art keywords
magnetic field
sample
particles
sensor
magnetisable particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020227044248A
Other languages
English (en)
Korean (ko)
Inventor
폴 제레미 킹
캠덴 융-와 로
Original Assignee
퀀텀 아이피 홀딩스 피티와이 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 퀀텀 아이피 홀딩스 피티와이 리미티드 filed Critical 퀀텀 아이피 홀딩스 피티와이 리미티드
Publication of KR20230013259A publication Critical patent/KR20230013259A/ko
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G01N33/547—Synthetic resin with antigen or antibody attached to the carrier via a bridging agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4737—C-reactive protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/525—Tumor necrosis factor [TNF]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/53—Colony-stimulating factor [CSF]
    • G01N2333/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5412—IL-6
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765—Serum albumin, e.g. HSA

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Electrochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Soft Magnetic Materials (AREA)
  • Compounds Of Iron (AREA)
KR1020227044248A 2020-05-25 2021-05-25 자성 나노 입자를 사용하는 분석물(들)의 검출 및 정량화 Pending KR20230013259A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2020904881 2020-05-25
AU2020904881 2020-05-25
PCT/AU2021/050497 WO2021237283A1 (en) 2020-05-25 2021-05-25 Use of magnetic nanoparticles for the detection and quantitation of analyte(s)

Publications (1)

Publication Number Publication Date
KR20230013259A true KR20230013259A (ko) 2023-01-26

Family

ID=78745678

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227044248A Pending KR20230013259A (ko) 2020-05-25 2021-05-25 자성 나노 입자를 사용하는 분석물(들)의 검출 및 정량화

Country Status (11)

Country Link
US (2) US11604187B2 (enExample)
EP (1) EP3938785A4 (enExample)
JP (1) JP7760582B2 (enExample)
KR (1) KR20230013259A (enExample)
CN (1) CN114341641A (enExample)
AU (2) AU2021232687B2 (enExample)
BR (1) BR112022023995A2 (enExample)
CA (1) CA3180264A1 (enExample)
IL (1) IL298373A (enExample)
MX (1) MX2022014818A (enExample)
WO (1) WO2021237283A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025063648A1 (ko) * 2023-09-19 2025-03-27 이화여자대학교 산학협력단 자성 센서에 기반하는 엔도뉴클레아제 동역학 측정장치 및 그 제조방법
KR20250108313A (ko) 2024-01-08 2025-07-15 고려대학교 산학협력단 기전력이 결부된 비대칭적 자기 수송 특성을 측정하는 장치

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114214391A (zh) * 2021-12-14 2022-03-22 徐州医科大学 Au/Fe3O4复合的磁纳米马达材料、制备方法及应用
JP2024142624A (ja) * 2023-03-30 2024-10-11 セイコーエプソン株式会社 生体物質抽出用磁性ビーズ
CN116660108A (zh) * 2023-05-31 2023-08-29 郑州轻工业大学 一种弱抗磁环境下的磁纳米颗粒核粒径分布信息估计方法
CN117434141A (zh) * 2023-10-13 2024-01-23 中国计量科学研究院 样品检测方法、装置、计算机设备和存储介质

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020123079A1 (en) * 2000-10-20 2002-09-05 Qi Chen Process for detecting or quantifying a biological rreaction using superparamagnetic label
US6825655B2 (en) * 2001-08-31 2004-11-30 Imego Ab Method and arrangement for detecting changes of a magnetic response in magnetic particles
AU2003244342A1 (en) * 2002-01-29 2003-09-02 Asahi Kasei Kabushiki Kaisha Biosensor, magnetic molecule measurement method, and measurement object measuring method
EP1651960A1 (en) * 2003-07-30 2006-05-03 Koninklijke Philips Electronics N.V. Use of magnetic particles for determining binding between bioactive molecules
US7906345B2 (en) * 2003-11-12 2011-03-15 The Board Of Trustees Of The Leland Stanford Junior University Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules
JP3962385B2 (ja) * 2004-03-11 2007-08-22 株式会社日立製作所 免疫検査装置及び免疫検査方法
GB0410980D0 (en) * 2004-05-17 2004-06-16 Randox Lab Ltd Magnetic particle detector system and method of performing binding assay
EP1896103A4 (en) * 2005-05-27 2009-12-09 Univ Texas OPTICAL COHERENCE TOMOGRAPHY DETECTION OF CELLS AND COMPOSITIONS
WO2007010368A1 (en) * 2005-07-20 2007-01-25 Inverness Medical Switzerland Gmbh Assay device and method
US20070197900A1 (en) * 2005-11-22 2007-08-23 Vanderbilt University Magnetic flow cytometer with SQUID microscopy
US20090227044A1 (en) * 2006-01-26 2009-09-10 Dosi Dosev Microchannel Magneto-Immunoassay
JP4837410B2 (ja) * 2006-03-22 2011-12-14 富士フイルム株式会社 標的化合物の検出方法
WO2011053435A1 (en) * 2009-10-05 2011-05-05 Scientific Nanomedicine, Inc. Cell detection using targeted nanoparticles and magnetic properties thereof
JP5189825B2 (ja) * 2007-11-05 2013-04-24 株式会社日立ハイテクノロジーズ 磁気信号計測装置および磁気信号計測方法
EP2220496A1 (en) * 2007-12-07 2010-08-25 Koninklijke Philips Electronics N.V. Magnetic washing for biosensor
WO2010098884A1 (en) * 2009-02-26 2010-09-02 Jian-Ping Wang High magnetic moment particle detection
EP2419733A4 (en) * 2009-04-13 2013-12-25 Univ Leland Stanford Junior METHODS AND DEVICES FOR DETECTING THE PRESENCE OF AN ANALYTE IN A SAMPLE
US8153442B2 (en) * 2009-10-21 2012-04-10 Siemens Healthcare Diagnostics Inc. Stabilization of signal generation in particles used in assays
US8927294B2 (en) * 2009-11-30 2015-01-06 Bio-Rad Laboratories Inc. Bead reader
CN102652259B (zh) * 2010-03-12 2016-07-27 小利兰·斯坦福大学托管委员会 基于磁性传感器的定量结合动力学分析
WO2012012596A2 (en) * 2010-07-22 2012-01-26 University Of Houston System Force-induced magnetization contrast for diagnosis and imaging
GB201014805D0 (en) * 2010-09-07 2010-10-20 Multi Sense Technologies Ltd Microfluidics based assay device
US9039992B2 (en) * 2011-06-06 2015-05-26 Abbott Laboratories Apparatus for closed tube sampling and open tube sampling for automated clinical analyzers
WO2013115725A1 (en) * 2012-02-03 2013-08-08 Neobios Pte Ltd A passive microfluidic device and a method of forming the same
JP5879189B2 (ja) * 2012-04-26 2016-03-08 株式会社日立製作所 交流磁場を用いた磁気的免疫検査方法及び検査装置
US20170022546A1 (en) * 2014-03-10 2017-01-26 Rashid Bashir Detection and quantification of methylation in dna
EP3295163B1 (en) * 2015-05-12 2020-12-02 Magarray, Inc. Devices and methods for increasing magnetic sensor sensitivity
JP6903672B2 (ja) * 2016-03-08 2021-07-14 マグアレイ，インコーポレイテッド 肺癌の診断および治療のための蛋白質と自己抗体バイオマーカー
US11318470B2 (en) * 2016-11-18 2022-05-03 Kansas State University Research Foundation Microfluidics-based nanobiosensors and devices
GB201707140D0 (en) * 2017-05-04 2017-06-21 Oxford Nanopore Tech Ltd Method
US11946035B2 (en) * 2017-05-16 2024-04-02 The Regents Of The University Of California Microfluidic-enabled multiwell cell culture devices and systems for precision culture, control and monitoring of living cells

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025063648A1 (ko) * 2023-09-19 2025-03-27 이화여자대학교 산학협력단 자성 센서에 기반하는 엔도뉴클레아제 동역학 측정장치 및 그 제조방법
KR20250108313A (ko) 2024-01-08 2025-07-15 고려대학교 산학협력단 기전력이 결부된 비대칭적 자기 수송 특성을 측정하는 장치

Also Published As

Publication number Publication date
JP2023528687A (ja) 2023-07-05
AU2021232687B2 (en) 2023-11-23
WO2021237283A1 (en) 2021-12-02
US11604187B2 (en) 2023-03-14
US20220003758A1 (en) 2022-01-06
AU2021232687A1 (en) 2021-12-09
TW202215051A (zh) 2022-04-16
IL298373A (en) 2023-01-01
AU2024201129A1 (en) 2024-03-14
US20230251249A1 (en) 2023-08-10
EP3938785A4 (en) 2022-11-30
CA3180264A1 (en) 2021-12-02
JP7760582B2 (ja) 2025-10-27
MX2022014818A (es) 2023-04-03
BR112022023995A2 (pt) 2023-02-07
CN114341641A (zh) 2022-04-12
EP3938785A1 (en) 2022-01-19

Similar Documents

Publication Publication Date Title
US11604187B2 (en) Use of magnetic nanoparticles for the detection and quantitation of analyte(s)
CN111954825B (zh) 基于超顺磁性纳米颗粒的分析方法和超顺磁性颗粒成像分析仪
EP2684036B1 (en) Systems and methods for high-throughput detection of an analyte in a sample
US20080206104A1 (en) Accurate Magnetic Biosensor
Dittmer et al. Sensitive and rapid immunoassay for parathyroid hormone using magnetic particle labels and magnetic actuation
JP2008544246A5 (enExample)
CN104838266B (zh) 借助可磁化珠粒检测分析物并且确定分析物浓度
JP2009020097A (ja) 生化学的分析方法
EP3295163B1 (en) Devices and methods for increasing magnetic sensor sensitivity
TWI906302B (zh) 用於偵測樣本中之分析物之方法及裝置
WO2024209449A1 (en) Method for detecting analytes
US20250020742A1 (en) Apparatus for detecting analytes
Wu et al. Magnetic Nanoparticle-Based Biosensing

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20221216

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20240514

Comment text: Request for Examination of Application