KR20210151188A - 뼈 및 관절 감염증의 치료 및 예방 방법 - Google Patents
뼈 및 관절 감염증의 치료 및 예방 방법 Download PDFInfo
- Publication number
- KR20210151188A KR20210151188A KR1020217036829A KR20217036829A KR20210151188A KR 20210151188 A KR20210151188 A KR 20210151188A KR 1020217036829 A KR1020217036829 A KR 1020217036829A KR 20217036829 A KR20217036829 A KR 20217036829A KR 20210151188 A KR20210151188 A KR 20210151188A
- Authority
- KR
- South Korea
- Prior art keywords
- gly
- val
- ala
- ser
- thr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Surgery (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962832754P | 2019-04-11 | 2019-04-11 | |
| US62/832,754 | 2019-04-11 | ||
| US201962849672P | 2019-05-17 | 2019-05-17 | |
| US62/849,672 | 2019-05-17 | ||
| US201962938812P | 2019-11-21 | 2019-11-21 | |
| US62/938,812 | 2019-11-21 | ||
| US202062964755P | 2020-01-23 | 2020-01-23 | |
| US62/964,755 | 2020-01-23 | ||
| PCT/US2020/027752 WO2020210691A1 (en) | 2019-04-11 | 2020-04-10 | Method of treating and preventing bone and joint infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210151188A true KR20210151188A (ko) | 2021-12-13 |
Family
ID=72752118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217036829A Pending KR20210151188A (ko) | 2019-04-11 | 2020-04-10 | 뼈 및 관절 감염증의 치료 및 예방 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220193186A1 (https=) |
| EP (1) | EP3980049A4 (https=) |
| JP (1) | JP2022526624A (https=) |
| KR (1) | KR20210151188A (https=) |
| CN (1) | CN114025783A (https=) |
| AU (1) | AU2020271116A1 (https=) |
| BR (1) | BR112021019884A2 (https=) |
| CA (1) | CA3136461A1 (https=) |
| IL (1) | IL286994A (https=) |
| MX (1) | MX2021012375A (https=) |
| WO (1) | WO2020210691A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023081691A1 (en) * | 2021-11-04 | 2023-05-11 | Contrafect Corporation | Method of treating and preventing bone and joint infections |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2833409A1 (en) * | 2011-04-21 | 2012-10-26 | The Rockefeller University | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| KR20210121313A (ko) * | 2012-05-09 | 2021-10-07 | 콘트라펙트 코포레이션 | 그람 양성 박테리아에 대한 박테리오파지 리신과 항생제의 병용물 |
| KR20200023521A (ko) * | 2012-05-09 | 2020-03-04 | 콘트라펙트 코포레이션 | 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료 |
| KR20190004799A (ko) * | 2016-05-12 | 2019-01-14 | 콘트라펙트 코포레이션 | 항균 폴리펩티드의 최소 억제 농도를 평가 및 탐지하기 위한 배지미량희석법 |
| KR20200124724A (ko) * | 2018-02-26 | 2020-11-03 | 콘트라펙트 코포레이션 | 변형된 PlySs2 리신 및 이의 용도 |
| CN112867398A (zh) * | 2018-06-22 | 2021-05-28 | 康特拉费克特公司 | 溶素及其衍生物使金黄色葡萄球菌和革兰氏阳性菌对抗生素重新敏感 |
-
2020
- 2020-04-10 EP EP20788204.4A patent/EP3980049A4/en not_active Withdrawn
- 2020-04-10 JP JP2021559424A patent/JP2022526624A/ja active Pending
- 2020-04-10 CA CA3136461A patent/CA3136461A1/en active Pending
- 2020-04-10 MX MX2021012375A patent/MX2021012375A/es unknown
- 2020-04-10 CN CN202080042979.2A patent/CN114025783A/zh active Pending
- 2020-04-10 KR KR1020217036829A patent/KR20210151188A/ko active Pending
- 2020-04-10 US US17/602,064 patent/US20220193186A1/en not_active Abandoned
- 2020-04-10 AU AU2020271116A patent/AU2020271116A1/en not_active Abandoned
- 2020-04-10 WO PCT/US2020/027752 patent/WO2020210691A1/en not_active Ceased
- 2020-04-10 BR BR112021019884A patent/BR112021019884A2/pt not_active IP Right Cessation
-
2021
- 2021-10-05 IL IL286994A patent/IL286994A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA3136461A1 (en) | 2020-10-15 |
| WO2020210691A1 (en) | 2020-10-15 |
| AU2020271116A1 (en) | 2021-11-11 |
| BR112021019884A2 (pt) | 2022-01-18 |
| IL286994A (en) | 2021-12-01 |
| JP2022526624A (ja) | 2022-05-25 |
| EP3980049A4 (en) | 2023-07-19 |
| US20220193186A1 (en) | 2022-06-23 |
| EP3980049A1 (en) | 2022-04-13 |
| CN114025783A (zh) | 2022-02-08 |
| MX2021012375A (es) | 2021-11-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP3091992B1 (en) | Phage therapy of e coli infections | |
| CN116077630A (zh) | 具有对抗革兰氏阴性菌的活性的溶素多肽 | |
| JP2024010053A (ja) | シュードモナス・エルギノーサに対する殺菌活性を有する溶解素及びその誘導体の特定 | |
| KR20010022237A (ko) | 리소스타핀을 단독 또는 항생제와의 조합으로 포함하는포도상구균 감염 치료용 약제학적 조성물 | |
| IL97344A (en) | Synergistic compositions containing béta-lactam antibiotics and cationic oligopeptides for treating infections | |
| KR20140142700A (ko) | 항균성 펩티드 | |
| KR20210024005A (ko) | 스태필로코커스 아우레우스 및 그람 양성 세균을 항생제에 재민감화시키기 위한 리신 및 이의 유도체 | |
| CN105963680B (zh) | 用于抑制/瓦解生物被膜的抑制剂及其应用 | |
| JP2021513865A (ja) | 修飾PlySs2溶解素及びその使用 | |
| US20210330738A1 (en) | Antimicrobial, bacteriophage-derived polypeptides and their use against gram-negative bacteria | |
| JP2025512749A (ja) | 感染症の新しい治療法 | |
| KR20210151188A (ko) | 뼈 및 관절 감염증의 치료 및 예방 방법 | |
| KR20230162045A (ko) | 그램-음성 박테리아에 대해 활성인 아무린, 리신, 및 리신-항미생물 펩타이드 (amp) 작제물 | |
| CN116406282A (zh) | 具有针对多药耐药性病原体的抗微生物活性的肽实体 | |
| JP2022526978A (ja) | ヒト血清の存在下でシュードモナス・エルギノーサに対する殺菌活性を有する溶解素及びその誘導体 | |
| US20220160842A1 (en) | Method of treating infective endocarditis | |
| RU2715694C1 (ru) | Фармацевтическая композиция для лечения глазных инфекций, вызванных метициллин-устойчивыми штаммами Staphylococcus aureus, включающая в качестве активного начала N-концевой CHAP-домен эндолизина бактериофага K Staphylococcus aureus | |
| RU2813626C1 (ru) | Модифицированный эндолизин и антибактериальные композиции на его основе для лечения инфекций, вызванных бактериями Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli | |
| EP3328412B1 (en) | Antimicrobial peptide for nosocomial infections | |
| WO2023081691A1 (en) | Method of treating and preventing bone and joint infections | |
| RU2807688C9 (ru) | Идентификация лизинов и их производных, обладающих антибактериальной активностью против pseudomonas aeruginosa | |
| RU2807688C2 (ru) | Идентификация лизинов и их производных, обладающих антибактериальной активностью против pseudomonas aeruginosa | |
| RU2804774C2 (ru) | Происходящие из бактериофагов противомикробные полипептиды и их применение против грамотрицательных бактерий | |
| JP2023526386A (ja) | グラム陽性細菌に対して使用される修飾PlySs2溶解素及び抗生物質の組合せ | |
| CN115209912A (zh) | 肽组合物及其使用方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
St.27 status event code: A-0-1-A10-A15-nap-PA0105 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| D21 | Rejection of application intended |
Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE) |
|
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| P11 | Amendment of application requested |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE) |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13 | Application amended |
Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE) |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| T11 | Administrative time limit extension requested |
Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T11-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE) |
|
| T11-X000 | Administrative time limit extension requested |
St.27 status event code: U-3-3-T10-T11-oth-X000 |
|
| T12 | Administrative time limit extension not granted |
Free format text: ST27 STATUS EVENT CODE: U-3-3-T10-T12-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE) |
|
| T12-X000 | Administrative time limit extension not granted |
St.27 status event code: U-3-3-T10-T12-oth-X000 |