KR20210132678A - 취약 x 정신 지체 단백질 간섭 올리고뉴클레오타이드 및 이를 사용하는 방법 - Google Patents
취약 x 정신 지체 단백질 간섭 올리고뉴클레오타이드 및 이를 사용하는 방법 Download PDFInfo
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- KR20210132678A KR20210132678A KR1020217030136A KR20217030136A KR20210132678A KR 20210132678 A KR20210132678 A KR 20210132678A KR 1020217030136 A KR1020217030136 A KR 1020217030136A KR 20217030136 A KR20217030136 A KR 20217030136A KR 20210132678 A KR20210132678 A KR 20210132678A
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- linkage
- antisense oligonucleotide
- fmrp
- seq
- antisense
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201962810697P | 2019-02-26 | 2019-02-26 | |
| US62/810,697 | 2019-02-26 | ||
| PCT/EP2020/055071 WO2020174023A1 (en) | 2019-02-26 | 2020-02-26 | Fragile x mental retardation protein interfering oligonucleotides and methods of using same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20210132678A true KR20210132678A (ko) | 2021-11-04 |
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| US (1) | US20220145303A1 (https=) |
| EP (1) | EP3931324A1 (https=) |
| JP (1) | JP2022521502A (https=) |
| KR (1) | KR20210132678A (https=) |
| CN (1) | CN113748207A (https=) |
| AU (1) | AU2020228134A1 (https=) |
| BR (1) | BR112021016907A2 (https=) |
| CA (1) | CA3130854A1 (https=) |
| EA (1) | EA202192330A1 (https=) |
| MX (1) | MX2021010255A (https=) |
| SG (1) | SG11202109112WA (https=) |
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| JP2025501755A (ja) * | 2021-12-23 | 2025-01-23 | ユニバーシティー オブ マサチューセッツ | 脆弱x関連障害に対する治療的処置 |
| CN121109315A (zh) * | 2025-08-28 | 2025-12-12 | 同济大学 | 脆性x智力障碍1号基因在治疗或缓解骨关节炎中的应用 |
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| RU2593939C2 (ru) | 2008-11-13 | 2016-08-10 | Ногра Фарма Лимитед | Антисмысловые композиции и способы их получения и применения |
| US8679757B2 (en) * | 2009-03-24 | 2014-03-25 | Asuragen, Inc. | PCR methods for characterizing the 5′ untranslated region of the FMR1 and FMR2 genes |
| EP2488665B1 (en) * | 2009-10-16 | 2017-12-13 | National University of Singapore | Screening method for trinucleotide repeat sequences |
| US20120231015A1 (en) * | 2009-11-06 | 2012-09-13 | Emory University | Fragile x mental retardation protein (fmrp), compositions, and methods related thereto |
| AU2011273360A1 (en) * | 2010-07-02 | 2013-02-07 | Vib Vzw | The role of Fragile X mental retardation gene and protein in cancer metastasis |
| CN103981253A (zh) * | 2014-03-27 | 2014-08-13 | 江苏佰龄全基因生物医学技术有限公司 | 一种用于检测脆性x染色体综合征的cgg重复数及agg插入信息的pcr试剂盒 |
| WO2017049192A1 (en) * | 2015-09-17 | 2017-03-23 | University Of Massachusetts | Compositions and methods for modulating fmr1 expression |
| EP3368089B1 (en) * | 2015-10-26 | 2025-11-05 | Translate Bio Ma, Inc. | Nanoparticle formulations for delivery of nucleic acid complexes |
| WO2019154884A1 (en) * | 2018-02-07 | 2019-08-15 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for determining cancer invasiveness and patient prognosis |
| CN108531576A (zh) * | 2018-04-12 | 2018-09-14 | 北京信诺佰世医学检验所有限公司 | 检测脆性x染色体综合征的试剂盒和系统 |
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- 2020-02-26 CA CA3130854A patent/CA3130854A1/en active Pending
- 2020-02-26 SG SG11202109112WA patent/SG11202109112WA/en unknown
- 2020-02-26 EP EP20707610.0A patent/EP3931324A1/en not_active Withdrawn
- 2020-02-26 KR KR1020217030136A patent/KR20210132678A/ko not_active Abandoned
- 2020-02-26 MX MX2021010255A patent/MX2021010255A/es unknown
- 2020-02-26 US US17/433,528 patent/US20220145303A1/en not_active Abandoned
- 2020-02-26 CN CN202080031598.4A patent/CN113748207A/zh active Pending
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- 2020-02-26 EA EA202192330A patent/EA202192330A1/ru unknown
- 2020-02-26 BR BR112021016907A patent/BR112021016907A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020174023A1 (en) | 2020-09-03 |
| EA202192330A1 (ru) | 2021-12-13 |
| CA3130854A1 (en) | 2020-09-03 |
| EP3931324A1 (en) | 2022-01-05 |
| MX2021010255A (es) | 2021-12-15 |
| BR112021016907A2 (pt) | 2021-11-03 |
| CN113748207A (zh) | 2021-12-03 |
| US20220145303A1 (en) | 2022-05-12 |
| JP2022521502A (ja) | 2022-04-08 |
| SG11202109112WA (en) | 2021-09-29 |
| AU2020228134A1 (en) | 2021-10-14 |
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