KR20210107338A - A method for making health supplement food including organic germamium and health supplement food thereby - Google Patents

Abstract

The present invention relates to a method for making health supplement food including organic germanium, which comprises the following steps: (a) preparing yeast containing a large amount of organic germanium; (b) acquiring an extract by hot water extraction of Angelica keiskei and Schisandra Schisandra; (c) preparing an Achyranthes japonica Nakai extract; and (d) mixing rice bran with an extract of Astragalus mongholicus, Angelica keiskei, and Schisandra Schisandra, a fermented Achyranthes japonica Nakai extract, the yeast obtained in the step (a), and honey and vacuum-drying and pulverizing the mixture into granules or powder. In the step (b), 70 g of each of Angelica keiskei and Schisandra Schisandra in the form of pieces is put in a container, 690 g of water is put in the container, and the mixture is heated at 110 to 135℃ for 7 to 9 hours to perform hot water extraction so that the extract becomes 80 to 100 g and is cooled. In the step (c), the step of preparing the Achyranthes japonica Nakai extract is performed by washing and pulverizing 200 g of dried Achyranthes japonica Nakai, putting the pulverized Achyranthes japonica Nakai in 300 g of water, and heating the mixture at 110 to 130℃ for 4 to 5 hours so that the extract becomes 90 to 110 g and is cooled. Accordingly, since the health supplement food can be added to salads in a granular or powder form, or added to cooking other foods, even the elderly can consume useful medicinal ingredients conveniently. The health supplement food provides excellent effects in the treatment, alleviation, and prevention of adult diseases such as degenerative diseases and rheumatoid arthritis and provides effects of germanium, which is known to have an immune-boosting effect, as well as effects on arthritis of Achyranthes japonica Nakai and effects of Angelica keiskei and Schisandra Schisandra.

Description

A method for manufacturing health supplements containing organic germanium and health supplements resulting therefrom

The present invention relates to a method of manufacturing a health supplement containing organic germanium and a health supplement therefor, and in particular, various cooking methods including salads so that various medicinal ingredients useful for the health of the elderly, including organic germanium, can be easily and efficiently ingested. It relates to a health supplement containing organic germanium manufactured in granular form so that it can be used by adding it to foods.

Recently, the elderly population is rapidly increasing, and these elderly people generally suffer from various diseases such as high blood pressure, diabetes, and arthritis along with deterioration of physical functions and reduced immunity due to aging.

These elderly people are taking many kinds of drugs to relieve pain and maintain health due to various diseases, and the cost burden of drugs taken for the prevention or treatment of these various diseases is very large and inconvenient to consume, Taking various medications puts a burden on the liver and stomach.

A method of ingestion as a health supplement to relieve the burden of treatment drugs using medicinal materials that have been widely known since ancient times has been widely used.

As an example of such a health supplement, germanium, which is known to have an excellent effect in the treatment, alleviation and prevention of adult diseases such as cancer, high blood pressure, diabetes, heart disease, degenerative diseases, and rheumatoid arthritis, and also has an immune enhancing effect, Since it is difficult to ingest this germanium in an inorganic form, organic germanium (Germanium, Ge) in which inorganic germanium ions are chemically combined with organic compounds such as amino acids or organic acids is used, for example, a domestic registered patent No. 0156661 discloses that in the human body cleansing composition containing organic germanium, organic germanium is contained in an amount of 0001 to 10% by weight based on the total weight of the composition, and oleic acid, lauric acid, linoleic acid, urea, and Azone (Azone) : 1-dodecylazacycloheptan-2-one) discloses a human body cleanser composition characterized in that it further contains 01 to 15% by weight of a skin adsorption accelerator selected from the group consisting of.

This organic germanium is also proposed in Korean Patent Registration No. 10-0658296 to use as a wrinkle-relieving cosmetic composition containing organic germanium, which promotes collagen synthesis in the dermis to relieve wrinkles and has excellent stability and safety in the formulation.

In addition, as a result of scientifically exploring the efficacy of organic germanium, a very effective interferon-inducing function, immunomodulatory action, anti-tumor effect, etc. have been reported (MTsutui et al, JAm Chem Soc 98,8278-8289 (1976), H Aso, et al Microbiol Immunol 29,65-74 (1985), FSuzuki RR Brutkiewicz aud RB Pollard, Anticancer Res 6,177-183 (1986)), as well as numerous patents and reports on the effects of organogermanium, representative examples has been reported to have acne relieving and therapeutic effects, antioxidant effects showing radical removal ability, UV damage protection effects, skin softening, abnormal pigmentation improvement effects, and atopic skin disease treatment effects ( JP

63183570, JP62111908, US4229468, US4889715, US4623667, KAsai Miracle cure:Organic Germanium,Japan Publications Inc ISBN 0-87040-1,1980)

However, it is difficult to extract such organic germanium in a state that can be easily ingested by humans, and thus commercially available organic germanium is expensive and difficult for many people to use widely.

In addition, numerous medicinal materials are used as health supplements. As an example, garlic used as a spice for various foods can be cited, and recently, garlic has antibacterial, anticancer, antithrombotic and antioxidant properties, etc. Garlic, scientifically proven to have the functionality of

As such, as well-known medicinal materials useful for health are individually consumed, there is a problem in that users are inconvenienced and the cost burden is excessive.

Domestic Registered Patent No. 0156661 Domestic Registered Patent No. 10-0658296

The present invention is to provide a health supplement containing organic germanium improved so that it can be conveniently used together with various medicinal ingredients in order to solve the problems of the conventional health supplement containing organic germanium.

In order to achieve the above object, the health supplement containing organic germanium according to the present invention, in the manufacturing method of the health supplement containing organic germanium,

(a) preparing yeast containing a large amount of organic germanium;

(b) obtaining an extract by hot water extraction of Angelica and Schisandra;

(c) the preparation step of the hyssop extract;

(d) mixing rice bran with the extract of Astragalus, Angelica oleifera, Schisandra extract, fermented hyssop extract, and the yeast obtained in step (a) with honey, and then vacuum-drying and pulverizing into granules or powder,

In step (b), 70 g each of Angelica and Schisandra in the form of pieces is put in a container, 690 g of water is added, heated at 110 to 135 ° C for 7 to 9 hours, hot water is extracted, and the extract is 80 to 100 g, and cooled at room temperature,

In the step (c), the manufacturing step of the hyssop extract is characterized in that 200 g of dried hyssop extract is washed and pulverized, put into 300 g of water, and heated at 110 to 130° C. for 4 to 5 hours so that the extract becomes 90 to 110 g, and then cooled. It is composed of organic germanium.

In step (d), it is preferable to prepare a mixture of 80-100 g of Angelica asiatica and Schisandra extract, 90-110 g of fermented hyssop extract, 300-400 g of rice bran and 50 g of honey, and vacuum-drying the mixture. .

In addition, before vacuum drying of the mixture in step (d), 10 to 15 g of manul powder and 10 to 20 g of turmeric powder may be added as auxiliary additives after vacuum drying steamed garlic in the mixture and then pulverized.

The health supplement according to the present invention can be added to salads in granular or powder form or added to cooking other foods, so that even the elderly can easily consume useful medicinal ingredients, degenerative diseases, rheumatoid arthritis, etc. In addition to the efficacy of germanium, which is known to have an excellent effect in the treatment, alleviation, and prevention of adult diseases, it also has an immune-boosting effect, as well as the efficacy of mussel against arthritis, and the effects of Angelica asiatica and omija.

1 is a schematic block diagram of a method for manufacturing a health supplement containing organic germanium according to the present invention.

The present invention will be described in more detail with reference to the accompanying drawings showing embodiments of the present invention.

In Figure 1, the method of manufacturing a health supplement containing organic germanium according to the present invention, (a) producing a yeast containing a large amount of organic germanium,

(b) obtaining an extract by applying heat at 130° C. for 8 hours, Angelica and Omija;

(c) the preparation step of the hyssop extract;

(d) mixing the rice bran with the extract of Astragalus, Angelica oleifera, Schisandra extract, fermented hyssop extract, and the yeast obtained in step (a) with honey, followed by vacuum drying and pulverizing into granular or powdery form.

As step (e), garlic and turmeric powder may be further added as auxiliary additives before vacuum drying in step (d).

The production of yeast containing organic germanium in step (a) is prepared in the same manner as disclosed in Korean Patent Publication No. 1997-0002248 to obtain yeast containing organic germanium. That is, the yeast is activated so that it can grow even in a medium containing 300 to 500% by weight of germanium with respect to the yeast cells, so that it can grow even under high-concentration germanium-added conditions where biological proliferation and activity are active. Saccharomyces cerevisiae is selected as a strain And, in order to activate the yeast, an alternating culture method of gradually increasing the germanium content on the medium was used.

At this time, in order to produce a high yield, a large amount of cells must be produced, so the experiment was conducted to increase the amount of germanium introduced per cell, and 4.2 to 5.2% of skim soy protein, 0.5 to 0.7% of yeast extract, glucose based on the weight of the total medium composition. Using a medium containing 6.5 to 7.5% as a basal medium for introducing a high concentration of organic germanium into yeast, the above activated yeast is added, and 0.01 to 0.1 weight of germanium based on the total medium composition during the growth logarithm of the activated yeast % and 5 to 7% by weight of glucose as a nutrient source were added, so a yeast in which a large amount of organic germanium was introduced into the activated yeast strain was prepared and then vacuum dried. This process yields 7 to 15 g of yeast.

In order to quantify the germanium introduced into the yeast prepared as above, phenylfluorone was reacted with germanium to form a complex, and this was analyzed using spectroscopic analysis to measure absorbance at 505 mm. It was found that the amount of organic germanium reaching

In step (b), Angelica chives and omija were placed in a container in the form of pieces and extracted with hot water to obtain an extract. At this time, hot water extraction was carried out by adding 70 g of Angelica persimmon and Schisandra perilla to 690 g of water and heating at 110 to 135° C. for 7 to 9 hours. At this time, the extract obtained by separating the remaining Angelica and Schisandra was made to be 80-100 g, and this was cooled at room temperature.

In the step (c), in the preparation step of the hyssop extract, 200 g of dried hyssop extract is washed and pulverized, put into 300 g of water, and heated at 110 to 130° C. for 4 to 5 hours to remove the hyssop residues so that the extract is 90 to 110 g. After cooling, hyssop extract was obtained. The hyssop extract was inoculated with 5% of pre-cultured Bacillus subtilis BN-NUC1 (Korea Microorganism Conservation Association (KCCM), Accession No. KCCM-10839, 2007 1 24), and fermented for 5 days in a temperature range of 40 to 45 ° C. A fermented hyssop extract obtained by fermentation may be used.

In step (d), a mixture of 80-100 g of Angelica asiatica and Schisandra extract, 90-110 g of fermented hyssop extract, 300-400 g of rice bran and 50 g of honey is prepared, and the mixture is vacuum-dried to form a granular health supplement. was prepared.

To the mixture obtained in step (d), vacuum-drying steamed garlic and then adding 10-15 g of pulverized manul powder and 10-20 g of turmeric powder as auxiliary additives may be vacuum-dried to prepare a granular health supplement.

The health supplements prepared as above were classified into 1 month's worth, and 10 men and women aged 60 years with arthritis symptoms were selected into 4 groups, and each group was given 10g, 12g, 15g, and 20g daily for 1 month and 2 months, respectively. , 3 months, 4 months and 5 months were ingested for sensory evaluation, and the results were shown in the table below.

Dosage/month of administration 1 month 2 months 3 months 4 months 5 months 10g No car (8 pax) light body (5) light body (5) Pain Relief (6) Pain Relief(7) 12g light body (6) Pain Relief(7) Pain Relief(8) Pain Relief(8) Pain Relief(7) 15g light body (8) Pain Relief(8) Pain Relief(8) Pain Relief(7) Pain Relief(8) 20g light body (8) Pain Relief(7) Pain Relief(8) Pain Relief(7) Pain Relief(8)

As can be seen above, at the time of administration of 10 g from each group of 10 people who took the dietary supplement according to the present invention, 8 people did not feel any relief, but from the 2nd month, the 5 people felt light, and from 5 months Seven people revealed that there was a pain-relieving effect, and from those who took 12g, six people said that their body felt light after 1 month, and from 2 months, 7-8 people said that they felt the pain was relieved. I could hear it, and after 5 months, 7 people said that the pain had disappeared. In addition, from those who received 15g and 20g, each of 8 people heard a statement that their body felt light after 1 month, and after 2 months, the pain subsided, and 7-8 people said that the pain disappeared. , there was no significant difference in efficacy at doses of 15 to 20 g.

Angelica has an anti-cancer effect and a blood pressure lowering action, and it has a blood-thinning action that makes blood circulate smoothly, and an anti-cancer effect and a blood pressure lowering action. , is known to be effective in soothing, joint pain, body weakness, headache, menstrual irregularity, abdominal pain, and constipation. don't do it It is known to be effective in diabetes, hyperhidrosis, nourishment, tonicity, electrolytes, and blood pressure enhancement when coughing due to poor lung, and hyssop is known to be effective in osteoarthritis or rheumatoid arthritis due to its excellent anti-inflammatory action.

The above results are broken as it was shown that the health supplement according to the present invention is effective because it can obtain the efficacy of Angelica and omija and the useful effects for arthritis of mussels along with the efficacy of germanium, and these health supplements are granulated It can be added to salads or added to cooking other foods, so that even the elderly can easily consume useful medicinal ingredients.

The present invention can be used for health supplements.

Claims (4)

In the manufacturing method of a health supplement containing organic germanium,
(a) preparing a yeast containing a large amount of organic germanium,
(b) obtaining an extract by hot water extraction of Angelica keiskei and Schisandra Schisandra;
(c) the preparation step of the hyssop extract;
(d) mixing rice bran with the extract of Astragalus, Angelica oleifera, Schisandra extract, fermented hyssop extract, and the yeast obtained in step (a) with honey, and then vacuum drying and pulverizing into granules or powder,
In step (b), 70 g each of Angelica chia and omija in the form of pieces is put in a container, and 690 g of water is heated at 110 to 135° C. for 7 to 9 hours to extract hot water, and the extract is 80 to 100 g, and cooled at room temperature,
In the step (c), the manufacturing step of the hyssop extract is characterized in that 200 g of dried hyssop is washed and pulverized, put into 300 g of water, and heated at 110 to 130 ° C. for 4 to 5 hours so that the extract becomes 90 to 110 g, and then cooled. A method of manufacturing health supplements containing organic germanium.
The method of claim 1,
In the step (d), a mixture of 80-100 g of Angelica asiatica and Schisandra extract, 90-110 g of fermented hyssop extract, 300-400 g of rice bran and 50 g of honey is prepared, and vacuum drying the mixture is characterized. A method of manufacturing health supplements containing organic germanium.
3. The method of claim 2,
Before vacuum drying of the mixture in step (d), vacuum-drying steamed garlic in the mixture, then adding 10-15 g of pulverized manul powder and 10-20 g of turmeric powder as auxiliary additives were vacuum-dried to obtain granular health supplements. A method of manufacturing a health supplement containing organic germanium, characterized in that for manufacturing a.
A health supplement manufactured according to any one of claims 1 to 3.

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