KR20130000817A - Fermented herbal medicine foods using effective micro-organisms and manufacturing method thereof - Google Patents

Abstract

PURPOSE: Ferment oriental medicine food and a manufacturing method thereof are provided to offer an effect on the treatment of depression effective microorganisms and an herbal medicine. CONSTITUTION: Select herbal medicines, and wash off contaminations. Dry each washed herbal medicine until the moisture is reduced into1-10%, and pulverizing the herbal medicines to obtain powder. Mix each herbal medicine and an effective microorganism compound with molasses or sugar, and water in a certain ration, and ferment the mixture. Dry each fermented herbal medicine to obtain powder. Mix the dried herbal medicine powder with water in a certain ration, and knead the mixture. Mold fermented herbal medicine powder batter into a ring shaped tablet using a tablet producer. Dry the ring shaped tablet with natural air or hot air. Mix the herbal medicins, molasses or sugar, effective microorganisms, and water in a weight ratio of 10:1:1:30. The herbal medicines are composed of 10-50% of beans, 1-10% of Rubus coreanus fruit, 1-10% of sweet potato, 1-10% of morus bark, 1-10% of mint, 1-10% of lycium, 1-10% of chrysanthemum, 1-10% of gaststickia, 1-10% of licorice, 1-10% of Paeonia japorica, 1-10% of Holen rubra, 1-10% of earth crust, 1-15% of Atractylodis Lanceae Rhizoma, 1-10% of Atractylodes japonica root, 1-10% of cnidium, 1-10% of gardenia seeds, 1-10% of Korean angelica root, 1-10% of forsythia fruit, 1-10% of Chinese yeast, 1-10% of barberry root, 1-20% of ginger, and 1-15% of Aurantii nobilis Pericarpium. The effective microorganisms is obtained by mixing 1-90wt% of lactobacillus, 1-90wt% of yeast fungus, and 1-90% of yeast fungus and photosynthetic bacteria mixture, and mixing the microorganism mixture with molasses or sugar in a weight proportion of 1:1 culturing without any supply of media under 20-40 deg. C for 3-6 months.

Description

Fermented herbal medicine foods using effective micro-organisms and manufacturing method

 The present invention relates to an antidepressant fermentation herbal foods using jade jade (善 玉 菌) and a method for manufacturing the same, more specifically, herbal medicines made by presenting medicinal herbs with jade for the prevention and treatment of anxiety, depression and dementia and memory enhancement The present invention relates to a pharmaceutical and a health supplement food formulated using the composition and a method of manufacturing the same.

Depression (melancholia) is one of the most common mental disorders in which people do not have an interest in everyday life and do not know the taste of despair. In addition to emotionally depressed and sad feelings, loss of interest or pleasure, loss of concentration, sleep disorders, weight loss, mental mobility impairment or delay, fatigue or vitality, worthlessness or excessive or inappropriate guilt, indecision, digestive disorders, suicide It is a dangerous psychiatric illness that can be accompanied by temptation. Depressive disorder is a lifelong prevalence of 15%, especially 25% in women, and is a serious disease that causes changes in feelings, thoughts, physical condition, and behavior. This affects an individual's overall life. Depression is different from temporary depression and is not an expression of personal weakness or a willingness to get rid of it. Many suffer from depression without the help of specialists, which is a pity. However, with proper medical care, you can expect a significant improvement and return to your normal life.

From ancient times to the present, the reality of depression is recognized to include symptoms of both depression and anxiety. Anxiety or depression often accompany each other. Depression can occur from younger students to the elderly, while women tend to appear earlier, but most of them are in their late 30s and early 40s. Depression usually lasts six months or more, suffers from physical and mental pain, and can lead to suicide if not treated properly.

Chinese medicine does not use the name of depression, but the Chinese term for depression is depression, which causes disorders in the body's physiological processes and causes functional disorders in the human body. The symptoms are emotional and always depressed mood and dislike of people or mental retardation, physical symptoms such as limb disability, anorexia, food discoloration or carbonation, It is recognized as chest pain (흉) or chest pain (胸痛) or mind and body unknown (心神 不明). This fits well with the aspect of the whole view that the body and mind are one and the approach of oriental medicine that emphasizes the concept of treatment before becoming sick. Therefore, the oriental medicine perception of depression is established and the dialectic standard is established to treat by oriental medical methods. Should be applied.

The present invention has been made in accordance with the necessity described above, by using fermented medicinal herb for the treatment of depression by using a useful microorganism, medicinal herbs to provide a pharmaceutical composition, a health food and a method for producing a pharmaceutical composition effective in the treatment of depression do.

In addition, the present invention is to provide a raw material of various drugs or processed foods effective for depression using a fermented herbal composition for improving depression.

Fermented herbal preparation method according to the present invention for solving the above problems,

(1) Soybean, malt, bokbunja, sweet potato, lettuce, peppermint, wolfberry, chrysanthemum, cheonma, licorice, white pear, red bokbokyeong, crust, dermis, creation, cheonggung, gardenia, donkey, fragrance, old and new, reflexion, dermis, ginger, cypress Selecting leaves with herbal medicine to wash impurities

(2) drying and pulverizing the washed medicinal herbs to have a water content of about 1 ~ 10% to prepare each powder

(3) fermenting each powdered herbal medicine and mixed jade bacteria with molasses or sugar and water in a predetermined ratio

(4) drying each fermented medicinal herb into powder

(5) mixing the dried fermented herbal medicine powder with water at a predetermined ratio and kneading

(6) step of preparing the kneaded fermented herbal medicine powder into a pill using a pill manufacturing apparatus

(7) drying the produced ring by natural drying or hot air.

As a preferred embodiment of the present invention, the jade bacteria contain lactic acid bacteria, yeast bacteria, photosynthetic bacteria, lactic acid bacteria 1-90% by weight, yeast 1-90% by weight, photosynthetic bacteria + yeasts 1-90% by weight, mixed Method for producing an anti-depressive fermented herbal medicine characterized in that the mixture of bacteria and sugar or molasses in a 1: 1 weight ratio and incubated for 3-6 months at 20 ~ 40 ℃ without supplying any medium

As a preferred embodiment of the present invention, the mixing ratio of the herbal medicine: molasses or sugar: jade jade bacteria: water in a ratio of 10: 1: 1: 30 by weight ratio, and in the fermentation drug bath at a temperature of 30 ~ 70 ℃ 24 ~ It is characterized by fermentation for 72 hours.

As a preferred embodiment of the present invention, the mixing ratio of each herbal is 10-50% soybean, malt 10-30%, bokbunja 1-15%, sweet potato 1-10%, baekbaek 1-10%, peppermint 1-10% , Goji 1-10%, Chrysanthemum 1-10%, Cheonma 1-10%, Licorice 1-10%, Earl 1-10%, Red Poetryling 1-10%, Crust 1-10%, Dermis weight ratio 1-15%, Creation weight ratio 1-10%, Cheongung 1-10%, Gardenia 1-10%, Angelica 1-10%, Fellowship 1-10%, New Kingdom 1-10%, Reunion 1-10%, Ginger 1-20%, White 1 to 15% by weight of the leaves are mixed, the water is characterized by kneading 10 to 40% by weight with respect to the mixture.

As a preferred embodiment of the present invention, it is characterized in that it further comprises the step of coating using honey in the prepared ring.

As a preferred embodiment of the present invention, by using the prepared fermented herbal medicine composition for improving depression, it is characterized in that it is used as a processed food for improving depression.

Depression-improved fermented herbal foods using jade jade according to the present invention is a fermented food containing herbal ingredients as a main ingredient has no side effects, limb disability, anorexia, dietary discoloration or carbonic acid (呑 酸) appearing in physical symptoms ), Chest pain (胸悶) or chest pain (胸痛) or mind and body (心神 不明) to alleviate depression is effective.

Specific embodiments for carrying out the present invention will be described in the following Examples, but the present invention is not limited by the following Examples.

Zenok bacteria in the present invention is a useful microbial group, such as lactic acid bacteria, yeast bacteria, naphtha bacteria, acetic acid bacteria and photosynthetic bacteria extracted from traditional fermented foods such as kimchi, soy sauce, red pepper paste, doenjang, cheonggukjang, salted fish, etc. In order to distinguish it from useful microorganisms collected from soil because of its safety, it is referred to as jade jade (善 玉 菌) in the present invention.

Specifically, Lactobacillus casei and Lactobacillus plantarum as lactic acid bacteria, Saccharomyces cerevisiae as yeast, and Bacillus subtilis as Bacillus bacteria Acetobacter aceti (Acetobacter aceti) as the acetic acid bacteria, Chlorobium as a photosynthetic bacterium is prepared. Each strain prepared in this way is cultured separately using sugar or molasses as a food source, and then blended according to the purpose of use and used as a conjugate bacterium.

Jade  to make

1. Incubate effective microorganisms, including lactic acid bacteria, yeast and photosynthetic bacteria, extracted from kimchi, soy sauce, red pepper paste, doenjang, cheonggukjang, and salted fish, which are traditional fermented foods, as a source of sugar or molasses.

2. 1 to 90% by weight of lactic acid bacteria, 1 to 90% by weight of lactic acid bacteria, 1 to 90% by weight of photosynthetic bacteria + yeast (a mixture of photosynthetic bacteria and yeast in a 1: 1 ratio) and sugar Mix in a weight ratio of 1 to form a mixture.

3. The mixture is incubated for 3-6 months at 20-40 ° C. without further supply of medium to form the jade.

Herbal medicine for the treatment of depression used in the present invention is soybean, malt, bokbunja, sweet potato, baekbaekpi, peppermint, wolfberry, chrysanthemum, cheonma, licorice, count, red bokbokyeong, perception, dermis, creation, cheonggung, gardenia, Angelica, poncho, old and new, Use dermis, ginger, and cypress leaves.

Fermented Herbal Medicine Making

1. Bean, malt, bokbunja, sweet potato, baekbaekpi, peppermint, wolfberry, chrysanthemum, cheonma, licorice, white pear, red bokbokyeong, crust, dermis, creation, cheonggung, gardenia, donkey, poncho, old and new, reflexion, dermis, ginger, cypress leaf It is selected as a herbal medicine to wash the impurities.

2. Dry the washed herbal medicine to have moisture content of 1 ~ 10%, and grind them into powder.

3. Each herbal powder and the mixed jade bacteria prepared in Example 1 are fermented by mixing molasses or sugar with water. The mixing ratio of the herbal medicine: molasses (sugar): jade bacteria: water in a ratio of 10: 1: 1: 30 in weight ratio, and fermented at a temperature of 30 ~ 70 ℃ for 24 hours to 72 hours.

4. Each fermented herbal medicine is dried and powdered.

5. Each dried fermented herb powder is mixed with water in a predetermined ratio and stirred in a stirrer for 1-2 hours.

 At this time, the mixing ratio of each herbal medicine is 10-50% of beans, 10-30% of malt, 1-15% of bokbunja, 1-10% of sweet potato, 1-10% of lettuce, 1-10% of peppermint, 1-10% of goji berries, chrysanthemum 1-10%, Cheonma 1-10%, Licorice 1-10%, Earl 1-10%, Red Rib 1-10%, Crust 1-10%, Dermal Weight Ratio 1-15%, Creation Weight Ratio 1-10%, Cheongung 1 to 10%, Gardenia 1 to 10%, Angelica 1 to 10%, Yeongyo 1 to 10%, 1 to 10% of new kingdoms, 1 to 10% of relativity, 1 to 20% of ginger, 1 to 15% of cypress leaves Mix and add 10-40% of water to the mixture by weight.

6. The kneaded fermented herbal medicine powder is prepared into a pill using a pill manufacturing apparatus.

The ring manufacturing apparatus is composed of a kneader, a stirrer and a purifier, and cut out the powder kneaded in the kneader while continuously ejecting from the stirrer, and in a constant size in the stirrer to make a ring like a ball.

7. The prepared ring is coated with honey.

8. The manufactured ring is dried by air drying or hot air drying.

[Experimental Example 1]

Depression improvement effect

Normally 20 men and women with depression symptoms (5 for each age group, 10 men and women each) take the pill prepared in Example 2 to take 20 tablets at a time three times a day for 1 month The result as shown in 1 and Table 2 was obtained. The improvement was 5 out of 1 point: no change, 2 points: slight improvement, 3 points: slight improvement, 4 points: significant improvement, 5 points: complete improvement, and the average value was obtained.

 division  Improvement degree (score) Side effects (persons)  Teenager 2.6 0  20's 3.2 0  30s 3.8 0  40 spaces 3.4 0

division Improvement degree (score)  south  2.9  female  3.6

Looking at the results of the experiment in Table 1, it was shown that the effect is slightly improved in the teenager, the improvement effect is high in the thirties. Table 2 shows that the improvement effect is greater for women than for men.

Claims (8)

In the fermented herbal medicine manufacturing method,
(1) Soybeans, malt, bokbunja, sweet potatoes, lettuce, peppermint, wolfberry, chrysanthemum, cheonma, licorice, earl, red bokbokyeong, crust, dermis, creation, cheonggung, gardenia, donkey, soft, old and new, reflexion, dermis, ginger, cypress Selecting leaves with herbal medicine to wash impurities
(2) drying and pulverizing the washed medicinal herbs to have a water content of about 1 ~ 10% to prepare each powder
(3) fermenting each herbal medicine powder and mixed jade bacteria mixed with molasses or sugar and water in a predetermined ratio
(4) drying each fermented medicinal herb into powder
(5) mixing the dried fermented herbal medicine powder with water at a predetermined ratio and kneading
(6) step of preparing the kneaded fermented herbal medicine powder into a pill using a pill manufacturing apparatus
(7) a method for producing an antidepressant-fermented herbal medicine comprising the step of drying the manufactured pill by natural drying or hot air The method of claim 1,
In step (3), the jade bacteria contain lactic acid bacteria, yeast bacteria, photosynthetic bacteria, lactic acid bacteria 1 to 90% by weight, yeast bacteria 1 to 90% by weight, photosynthetic bacteria + yeasts 1 to 90% by weight, mixed bacteria and sugar Alternatively, the method for preparing depression-improving fermented herbal medicine characterized in that the molasses is mixed in a 1: 1 weight ratio and cultured for 3 to 6 months at 20-40 ° C. without supplying any medium. The method of claim 1,
In the step (3), the mixing ratio of the herbal medicine: molasses or sugar: jade jade bacteria: water in a ratio of 10: 1: 1: 30 weight ratio manufacturing method for improving fermentation depression The method of claim 1,
The step (3) is a fermentation herb medicine manufacturing method for improving depression, characterized in that fermentation at a temperature of 30 ~ 70 ℃ 24 ~ 72 hours The method of claim 1,
In the step (5), the mixing ratio of each herb is 10-50% soybean, malt 10-30%, bokbunja 1-15%, sweet potato 1-10%, lettuce 1-10%, peppermint 1-10%, goji 1 ~ 10%, Chrysanthemum 1 ~ 10%, Cheonma 1 ~ 10%, Licorice 1 ~ 10%, Earl 1 ~ 10%, Red Poetryling 1 ~ 10%, Crust 1 ~ 10%, Dermis weight ratio 1 ~ 15%, Creation weight ratio 1 ~ 10%, Cheongung 1-10%, Gardenia 1-10%, Angelica 1-10%, Fellowship 1-10%, New Kingdom 1-10%, Reunion 1-10%, Ginger 1-20%, Cypress Leaf 1 ~ Method for producing an anti-depressive fermentation medicinal herb characterized in that the mixture of 15% by weight, and water to knead 10 to 40% by weight with respect to the mixture The method of claim 1,
Method for producing a depression improvement fermented herbal medicine characterized in that it further comprises the step of coating the honey using a ring prepared between the steps (6) and (7) Fermented herbal composition for improving depression prepared by the method of any one of claims 1 to 6. Depression improvement fermented herbal medicine processed food using the fermented herbal composition of claim 7