KR20200077534A - 이종 단백질 생성을 위한 인공 분비 펩티드 - Google Patents
이종 단백질 생성을 위한 인공 분비 펩티드 Download PDFInfo
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- KR20200077534A KR20200077534A KR1020207014298A KR20207014298A KR20200077534A KR 20200077534 A KR20200077534 A KR 20200077534A KR 1020207014298 A KR1020207014298 A KR 1020207014298A KR 20207014298 A KR20207014298 A KR 20207014298A KR 20200077534 A KR20200077534 A KR 20200077534A
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
Landscapes
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| US201862691553P | 2018-06-28 | 2018-06-28 | |
| US62/691,553 | 2018-06-28 | ||
| PCT/US2018/056610 WO2019079663A1 (en) | 2017-10-20 | 2018-10-19 | ARTIFICIAL SECRETING PEPTIDES FOR THE PRODUCTION OF HETEROLOGOUS PROTEINS |
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| US20240166694A1 (en) * | 2021-03-19 | 2024-05-23 | Tenza, Inc. | Synthetic pre-protein signal peptides for directing secretion of heterologous proteins in bacillus bacteria |
| US20250382625A1 (en) * | 2022-05-12 | 2025-12-18 | Tenza, Inc. | Synthetic pre-protein signal peptides for directing secretion of heterologous proteins in escherichia bacteria |
| WO2024145571A2 (en) * | 2022-12-30 | 2024-07-04 | Tenza, Inc. | Artificial secretion peptides for heterologous protein production |
| WO2025146497A1 (en) * | 2024-01-05 | 2025-07-10 | National University Of Singapore | Methods for drug delivery |
| CN118813504B (zh) * | 2024-09-19 | 2025-02-07 | 青岛诺和诺康生物科技有限公司 | 改善血栓和血管健康的卷曲乳杆菌及其制品和应用 |
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| US5733540A (en) | 1995-03-08 | 1998-03-31 | Lee; Peter Poon-Hang | Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria |
| US6093394A (en) | 1997-04-11 | 2000-07-25 | Gynelogix, Inc. | Vaginal lactobacillus medicant |
| JP2002017357A (ja) * | 2000-07-04 | 2002-01-22 | Calpis Co Ltd | アンカーペプチド、融合蛋白質、及び蛋白質の固定化方法 |
| AU2003276822A1 (en) | 2002-03-08 | 2004-02-02 | Osel, Inc. | Lactobacilli expressing biologically active polypeptides and uses thereof |
| US20090226418A1 (en) | 2005-08-19 | 2009-09-10 | Leo Gerardus Frenken | Food Products Comprising Probiotic Micro-Organisms and Antibodies |
| US20080051317A1 (en) | 2005-12-15 | 2008-02-28 | George Church | Polypeptides comprising unnatural amino acids, methods for their production and uses therefor |
| US20110104121A1 (en) | 2008-05-21 | 2011-05-05 | Wira Charles R | Female Reproductive Tract and Anal Prophylaxes |
| GB0821729D0 (en) * | 2008-11-28 | 2008-12-31 | Plant Bioscience Ltd | Composition and method for enhanced secretion of peptides and proteins from bacteria |
| WO2010077682A2 (en) | 2008-12-08 | 2010-07-08 | James Allen Lemke | Treatment of hiv and aids using probiotic lactobacillus reuteri |
| EP2556085A2 (en) | 2010-04-05 | 2013-02-13 | Bar-Ilan University | Protease-activatable pore-forming polypeptides |
| CA2802994A1 (en) | 2010-06-17 | 2011-12-22 | The United States Of America As Represented By The Secretary, National I Nstitutes Of Health | Compositions and methods for treating inflammatory conditions |
| GB2482536B (en) | 2010-08-05 | 2013-07-24 | Hera Pharmaceuticals Inc | Expression of antibody or a fragment thereof in lactobacillus |
| CN104781401B (zh) * | 2012-10-26 | 2018-06-05 | 独立行政法人产业技术综合研究所 | 人工生物发光酶 |
| JP6835586B2 (ja) | 2014-01-31 | 2021-02-24 | シトムクス セラピューティクス，インコーポレイティド | マトリプターゼ及びｕ‐プラスミノーゲン活性化因子の基質及び他の切断可能部分、並びにその使用方法 |
| CA3025020A1 (en) | 2016-05-20 | 2017-11-23 | President And Fellows Of Harvard College | Gene therapy methods for age-related diseases and conditions |
| KR102348734B1 (ko) * | 2016-09-13 | 2022-01-07 | 인트랙슨 액토바이오틱스 엔.브이. | 점막부착성 미생물 |
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| WO2024022791A1 (de) * | 2022-07-28 | 2024-02-01 | Inm - Leibniz-Institut Für Neue Materialien Gemeinnützige Gmbh | Neuartige genetische werkzeuge |
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