KR20200026874A - 대장균 개량을 위한 htp 게놈 공학 플랫폼 - Google Patents

대장균 개량을 위한 htp 게놈 공학 플랫폼 Download PDF

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KR20200026874A
KR20200026874A KR1020207000237A KR20207000237A KR20200026874A KR 20200026874 A KR20200026874 A KR 20200026874A KR 1020207000237 A KR1020207000237 A KR 1020207000237A KR 20207000237 A KR20207000237 A KR 20207000237A KR 20200026874 A KR20200026874 A KR 20200026874A
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coli strain
gene
library
coli
swap
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자흐 서버
에릭 제데디아 딘
쇼운 맨체스터
캐서린 고라
에린 쉘만
애론 킴볼
쇼운 시카
바바라 프레웬
토마스 트레이너
마이클 플래쉬맨
로버트 하우스할터
스테이시-앤 모건
마이클 블레세
프라바 라마크리시난
카일 로스차일드-마취넬리
영년 김
매튜 데이비스
크리스티 위즈뉴스키
패트릭 웨스트폴
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지머젠 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
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  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Ecology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020207000237A 2017-06-06 2018-06-06 대장균 개량을 위한 htp 게놈 공학 플랫폼 Withdrawn KR20200026874A (ko)

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US201762515870P 2017-06-06 2017-06-06
US62/515,870 2017-06-06
PCT/US2018/036333 WO2018226880A1 (en) 2017-06-06 2018-06-06 A htp genomic engineering platform for improving escherichia coli

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US (1) US20200370058A1 (enExample)
EP (2) EP3485013B1 (enExample)
JP (1) JP2020524490A (enExample)
KR (1) KR20200026874A (enExample)
CN (1) CN110945125A (enExample)
CA (1) CA3064612A1 (enExample)
ES (1) ES2875579T3 (enExample)
WO (1) WO2018226880A1 (enExample)

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WO2025101028A1 (ko) * 2023-11-10 2025-05-15 한국과학기술원 TdT(Terminal deoxynucleotidyl transferase) 및 dNTP를 이용한 비번역영 역 (untranslated region) 라이브러리 합성 방법

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CN114921463B (zh) * 2022-04-11 2023-12-01 中国农业科学院生物技术研究所 一种调控萜类化合物合成产量的人工非编码RNA分子CsiY及其应用
CN115074410B (zh) * 2022-06-30 2025-08-19 武汉合生科技有限公司 一种生物合成虾青素的方法及载体
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CN115820703A (zh) * 2022-12-20 2023-03-21 山东乾肽生物科技有限公司 利用rna环化技术制备寡肽的方法及寡肽的表达dna
CN116013407B (zh) * 2022-12-26 2025-06-27 杭州智科慧创科技有限公司 一种基于语言模型的性质解耦蛋白质生成方法
CN116504313A (zh) * 2023-05-08 2023-07-28 暨南大学 基因终止子查询方法、装置、设备及可读存储介质
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
WO2025101028A1 (ko) * 2023-11-10 2025-05-15 한국과학기술원 TdT(Terminal deoxynucleotidyl transferase) 및 dNTP를 이용한 비번역영 역 (untranslated region) 라이브러리 합성 방법

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JP2020524490A (ja) 2020-08-20
CA3064612A1 (en) 2018-12-13
EP3485013B1 (en) 2021-03-24
ES2875579T3 (es) 2021-11-10
EP3485013A1 (en) 2019-05-22
WO2018226880A1 (en) 2018-12-13
US20200370058A1 (en) 2020-11-26
CN110945125A (zh) 2020-03-31
EP3878961A1 (en) 2021-09-15

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