KR20200026874A - 대장균 개량을 위한 htp 게놈 공학 플랫폼 - Google Patents

대장균 개량을 위한 htp 게놈 공학 플랫폼 Download PDF

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KR20200026874A
KR20200026874A KR1020207000237A KR20207000237A KR20200026874A KR 20200026874 A KR20200026874 A KR 20200026874A KR 1020207000237 A KR1020207000237 A KR 1020207000237A KR 20207000237 A KR20207000237 A KR 20207000237A KR 20200026874 A KR20200026874 A KR 20200026874A
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coli strain
gene
library
coli
swap
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자흐 서버
에릭 제데디아 딘
쇼운 맨체스터
캐서린 고라
에린 쉘만
애론 킴볼
쇼운 시카
바바라 프레웬
토마스 트레이너
마이클 플래쉬맨
로버트 하우스할터
스테이시-앤 모건
마이클 블레세
프라바 라마크리시난
카일 로스차일드-마취넬리
영년 김
매튜 데이비스
크리스티 위즈뉴스키
패트릭 웨스트폴
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지머젠 인코포레이티드
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
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  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
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  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Ecology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020207000237A 2017-06-06 2018-06-06 대장균 개량을 위한 htp 게놈 공학 플랫폼 Withdrawn KR20200026874A (ko)

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Application Number Priority Date Filing Date Title
US201762515870P 2017-06-06 2017-06-06
US62/515,870 2017-06-06
PCT/US2018/036333 WO2018226880A1 (en) 2017-06-06 2018-06-06 A htp genomic engineering platform for improving escherichia coli

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US (1) US20200370058A1 (enExample)
EP (2) EP3485013B1 (enExample)
JP (1) JP2020524490A (enExample)
KR (1) KR20200026874A (enExample)
CN (1) CN110945125A (enExample)
CA (1) CA3064612A1 (enExample)
ES (1) ES2875579T3 (enExample)
WO (1) WO2018226880A1 (enExample)

Cited By (1)

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WO2025101028A1 (ko) * 2023-11-10 2025-05-15 한국과학기술원 TdT(Terminal deoxynucleotidyl transferase) 및 dNTP를 이용한 비번역영 역 (untranslated region) 라이브러리 합성 방법

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CN111612133B (zh) * 2020-05-20 2021-10-19 广州华见智能科技有限公司 基于人脸图像多阶段关系学习的内脏器官特征编码方法
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CN114921463B (zh) * 2022-04-11 2023-12-01 中国农业科学院生物技术研究所 一种调控萜类化合物合成产量的人工非编码RNA分子CsiY及其应用
CN115074410B (zh) * 2022-06-30 2025-08-19 武汉合生科技有限公司 一种生物合成虾青素的方法及载体
CN115992160A (zh) * 2022-09-30 2023-04-21 倍生生物科技(深圳)有限公司 一种穿梭载体及其构建方法和应用
CN115820703B (zh) * 2022-12-20 2026-07-10 山东乾肽生物科技有限公司 利用rna环化技术制备寡肽的方法及寡肽的表达dna
CN116013407B (zh) * 2022-12-26 2025-06-27 杭州智科慧创科技有限公司 一种基于语言模型的性质解耦蛋白质生成方法
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
WO2025101028A1 (ko) * 2023-11-10 2025-05-15 한국과학기술원 TdT(Terminal deoxynucleotidyl transferase) 및 dNTP를 이용한 비번역영 역 (untranslated region) 라이브러리 합성 방법

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CA3064612A1 (en) 2018-12-13
EP3485013A1 (en) 2019-05-22
WO2018226880A1 (en) 2018-12-13
EP3485013B1 (en) 2021-03-24
CN110945125A (zh) 2020-03-31
ES2875579T3 (es) 2021-11-10
US20200370058A1 (en) 2020-11-26
JP2020524490A (ja) 2020-08-20
EP3878961A1 (en) 2021-09-15

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