KR20190086655A - 저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도 - Google Patents

저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도 Download PDF

Info

Publication number
KR20190086655A
KR20190086655A KR1020197001664A KR20197001664A KR20190086655A KR 20190086655 A KR20190086655 A KR 20190086655A KR 1020197001664 A KR1020197001664 A KR 1020197001664A KR 20197001664 A KR20197001664 A KR 20197001664A KR 20190086655 A KR20190086655 A KR 20190086655A
Authority
KR
South Korea
Prior art keywords
gelatin
salmon
amino acid
composition
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020197001664A
Other languages
English (en)
Korean (ko)
Inventor
카세레스 하비에르 엔리오네
파울로 디아즈-칼데론
알레산드로 자우파
콕스 후안 파블로 아세베도
Original Assignee
유니버시다드 데 로스 안데스
셀즈 포 셀즈, 에스.피.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 유니버시다드 데 로스 안데스, 셀즈 포 셀즈, 에스.피.에이. filed Critical 유니버시다드 데 로스 안데스
Publication of KR20190086655A publication Critical patent/KR20190086655A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P20/00—Coating of foodstuffs; Coatings therefor; Making laminated, multi-layered, stuffed or hollow foodstuffs
    • A23P20/10—Coating with edible coatings, e.g. with oils or fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y70/00—Materials specially adapted for additive manufacturing
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/06—Ethers; Acetals; Ketals; Ortho-esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/10—Esters; Ether-esters
    • C08K5/101—Esters; Ether-esters of monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D11/00—Inks
    • C09D11/02—Printing inks
    • C09D11/04—Printing inks based on proteins
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09H—PREPARATION OF GLUE OR GELATINE
    • C09H7/00—Preparation of water-insoluble gelatine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/461—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from fish
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2389/00—Characterised by the use of proteins; Derivatives thereof
    • C08J2389/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08J2389/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2312/00—Crosslinking

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Artificial Filaments (AREA)
  • Polymerisation Methods In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Wood Science & Technology (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
KR1020197001664A 2016-06-17 2017-06-19 저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도 Ceased KR20190086655A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16175153 2016-06-17
EP16175153.2 2016-06-17
PCT/IB2017/053637 WO2017216780A1 (en) 2016-06-17 2017-06-19 Gelatin polymer derived from natural sources of cold-adapted marine species and uses thereof

Publications (1)

Publication Number Publication Date
KR20190086655A true KR20190086655A (ko) 2019-07-23

Family

ID=56368780

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197001664A Ceased KR20190086655A (ko) 2016-06-17 2017-06-19 저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도

Country Status (11)

Country Link
US (1) US11566133B2 (https=)
EP (1) EP3472229B1 (https=)
JP (1) JP2019525990A (https=)
KR (1) KR20190086655A (https=)
CN (1) CN109952341A (https=)
AU (1) AU2017285384A1 (https=)
CA (1) CA3028114A1 (https=)
CL (3) CL2018003648A1 (https=)
IL (1) IL263733A (https=)
RU (1) RU2019101011A (https=)
WO (1) WO2017216780A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220008585A (ko) * 2020-07-14 2022-01-21 바오밥헬스케어 주식회사 줄기세포 대량생산용 배양배드 및 이의 제조 방법

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020505345A (ja) 2017-01-16 2020-02-20 セルズ フォー セルズ エセ．アー． 乏血小板血漿（ｐｐｐ）に封入された実質的に純粋な多能性間質細胞集団を含む組成物
CN119264211A (zh) 2018-08-27 2025-01-07 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
EP3719057A1 (en) 2019-04-03 2020-10-07 Tessenderlo Group NV A gelatin and uses thereof
US12180374B2 (en) 2019-06-18 2024-12-31 University Of Washington Protein-based resins for additive manufacturing
WO2021054232A1 (ja) * 2019-09-18 2021-03-25 国立研究開発法人物質・材料研究機構 生体組織接着シート、生体組織補強材料キット、及び、生体組織接着シートの製造方法
JP7604801B2 (ja) * 2019-12-19 2024-12-24 ａｒｔｉｅｎｃｅ株式会社 細胞培養用インクジェットインキ、細胞培養用部材及びその製造方法、細胞培養パターンの形成方法
CN112071660B (zh) * 2020-08-03 2021-08-24 陕西国防工业职业技术学院 一种超长聚吡咯纳米线型电极材料的制备方法
CN112679593B (zh) * 2020-12-28 2023-01-03 华中农业大学 酸处理结合壳聚糖絮凝回收鱼糜漂洗液中的肌浆蛋白的方法及应用
WO2023287469A1 (en) * 2021-07-16 2023-01-19 The Regents Of The University Of California Reusable environmentally friendly food cooling technology
EP4582439A1 (en) 2022-09-01 2025-07-09 Cells For Cells S.A. Method for obtainingmethod for obtaining a porous injectable scaffold based on similar biopolymers with different melting temperatures
EP4626957A1 (en) * 2022-12-02 2025-10-08 Gelomics Pty Ltd Modified gelatins, hydrogels, and processes for their production
DE102023120769A1 (de) 2023-08-04 2025-02-06 Cellbricks Gmbh Verfahren zur herstellung einer tinte für den 3d-druck unter verwendung eines polypeptids auf basis von menschlichem kollagen mit reduziertem hydroxyprolin-anteil
CN117045846B (zh) * 2023-08-21 2026-01-06 天津工业大学 一种高分子量壳聚糖皮芯结构微纳米纤维敷料

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2124537C1 (ru) 1996-07-04 1999-01-10 Научно-исследовательский институт военной медицины Композиция и способ изготовления контактной линзы
JPH10195169A (ja) * 1997-01-13 1998-07-28 Showa Denko Kk 重合性を付与した天然有機高分子化合物の製造方法
US6458386B1 (en) * 1997-06-03 2002-10-01 Innogenetics N.V. Medicaments based on polymers composed of methacrylamide-modified gelatin
FR2839658B1 (fr) * 2002-05-17 2004-08-06 Protex Nouveau procede de preparation de microcapsules a base de gelatine, contenant un liquide hydrophobe et microcapsules obtenues
CA2393720C (en) 2002-07-12 2010-09-14 Eli Lilly And Company Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride
AT501700B1 (de) * 2005-04-14 2011-03-15 Univ Wien Tech Mit strahlung härtbare, biologisch abbaubare zusammensetzungen und deren verwendung als stützmaterialien für den knochenersatz
RU2486907C2 (ru) 2006-12-04 2013-07-10 Джонс Хопкинс Юниверсити Имидированный биополимерный адгезив и гидрогель
EP1961414A1 (en) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. A controlled release composition comprising a recombinant gelatin
EP1961411A1 (en) * 2007-02-21 2008-08-27 FUJIFILM Manufacturing Europe B.V. A controlled release composition
EP2487206A3 (en) * 2008-06-18 2012-11-28 Lifebond Ltd Cross-linkable gelatin-based compositions
GB0907323D0 (en) 2009-04-29 2009-06-10 Dynea Oy Composite material comprising crosslinkable resin of proteinous material
US8658711B2 (en) 2010-09-29 2014-02-25 Rutgers, The State University Of New Jersey Process for the synthesis of methacrylate-derivatized type-1 collagen and derivatives thereof
GB201305281D0 (en) * 2013-03-22 2013-05-01 Univ Leeds Improvements in and relating to collagen based materials
CN103319729B (zh) * 2013-06-04 2015-10-28 武汉工程大学 一种功能明胶改性的方法
RU2564824C1 (ru) 2014-07-11 2015-10-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарёва" Биоразлагаемая пленка
CN104448161B (zh) * 2014-12-05 2017-02-22 四川大学 一种改性明胶纳米微球交联的有机复合水凝胶及其制备方法
EP3362073A4 (en) 2015-10-13 2019-05-08 Cells For Cells S.A. ANTIANGIOGENIC THERAPY BASED ON EXOSOMES FROM MENSTRUELLEN STEM CELLS
EP3362044A4 (en) 2015-10-14 2019-05-29 Cells For Cells S.A. TREATMENT AGAINST INFECTION COMPOSED OF MENSTRUAL BLOOD STEM CELLS
EP3361986B1 (en) 2015-10-14 2021-01-06 Universidad de los Andes Automated fabrication of layer-by-layer tissue engineered complex tubes
JP2020505345A (ja) 2017-01-16 2020-02-20 セルズ フォー セルズ エセ．アー． 乏血小板血漿（ｐｐｐ）に封入された実質的に純粋な多能性間質細胞集団を含む組成物

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20220008585A (ko) * 2020-07-14 2022-01-21 바오밥헬스케어 주식회사 줄기세포 대량생산용 배양배드 및 이의 제조 방법

Also Published As

Publication number Publication date
WO2017216780A1 (en) 2017-12-21
AU2017285384A1 (en) 2019-02-07
RU2019101011A (ru) 2020-07-17
EP3472229B1 (en) 2022-02-16
CL2021000763A1 (es) 2021-10-22
US11566133B2 (en) 2023-01-31
CA3028114A1 (en) 2017-12-21
US20190194460A1 (en) 2019-06-27
RU2019101011A3 (https=) 2020-10-06
JP2019525990A (ja) 2019-09-12
EP3472229A1 (en) 2019-04-24
CL2021000762A1 (es) 2021-10-22
IL263733A (en) 2019-01-31
CL2018003648A1 (es) 2019-05-31
CN109952341A (zh) 2019-06-28

Similar Documents

Publication Publication Date Title
KR20190086655A (ko) 저온-적응된 해양생물종의 천연 공급원으로부터 유래된 젤라틴 중합체 및 그것의 용도
Chandika et al. Fish collagen/alginate/chitooligosaccharides integrated scaffold for skin tissue regeneration application
Agheb et al. Novel electrospun nanofibers of modified gelatin-tyrosine in cartilage tissue engineering
CA2956075C (en) Modified alginates for anti-fibrotic materials and applications
US11998658B2 (en) Injectable porous hydrogels
Yuan et al. Biocompatible gellan gum/sericin hydrogels containing halloysite@ polydopamine nanotubes with hemostasis and photothermal antibacterial properties for promoting infectious wound repair
JP5870398B2 (ja) 高強度コラーゲン線維膜及びその製造方法
JP2020196752A (ja) コラーゲンに基づく治療送達系
JP2010053080A (ja) キトサンとコラーゲンを含む構造体
Khoshnood et al. Development of novel alginate‐polyethyleneimine cell‐laden bioink designed for 3D bioprinting of cutaneous wound healing scaffolds
Sionkowska et al. The influence of UV irradiation on the properties of chitosan films containing keratin
EP3862016B1 (en) Angiogenesis promoter for use in treating a peripheral artery disease
Chen ColMA/PEGDA bioink for digital light processing 3D printing in biomedical engineering
Martinez et al. Development of biocompatible scaffolds of collagen fibers from Tilapia scales (Oreochromis niloticus) modified with PVA
Naeimipour et al. Multimodal and dynamic cross-linking of modular thiolated alginate-based bioinks
IT202000005692A1 (it) Bio-inchiostro per stampa 3D, relativo coniugato e processo di preparazione di un intermedio costituito da un linker fotoreattivo
BE1031493B1 (nl) Gebruik van gelatine in een ondersteuningsmateriaal voor ingebed printen
JP2023527796A (ja) インサイチュゲル化両性イオン性ヒドロゲル組成物、及びその使用方法
Pai et al. Radical scavenging gelatin methacrylamide based bioink formulation for three dimensional bioprinting of parenchymal liver construct
Kim et al. Enhanced wound healing via stem cell migration using a substance P1-loaded cross-linked small intestinal submucosa scaffold
Jiang et al. Injectable multifunctional modified sodium alginate microparticles for rapid hemostasis and wound repair following endoscopic submucosal dissection
KR20240038590A (ko) 가시광선 경화용 바이오잉크 조성물, 이것의 제조 방법 및 프린팅 방법
Anbuselvan et al. Extraction and Characterization of Fish Collagen for Enhanced Wound Healing Activity on A549 Cell Lines
Hammer Multi-scale biomimetic hybrid membranes for skin tissue engineering
Huang et al. Thermosensitive drug-loaded hydrogel based on natural collagen for diabetic wound management via modulating inflammation and promoting angiogenesis

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20190117

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20200610

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20210712

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20211115

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20210712

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I