KR20190082197A - 미소 구체 및 그 제조 방법 - Google Patents

미소 구체 및 그 제조 방법 Download PDF

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Publication number
KR20190082197A
KR20190082197A KR1020197009734A KR20197009734A KR20190082197A KR 20190082197 A KR20190082197 A KR 20190082197A KR 1020197009734 A KR1020197009734 A KR 1020197009734A KR 20197009734 A KR20197009734 A KR 20197009734A KR 20190082197 A KR20190082197 A KR 20190082197A
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KR
South Korea
Prior art keywords
microspheres
less
carrier
microsphere
superhydrophilic surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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KR1020197009734A
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English (en)
Korean (ko)
Inventor
댄 리위투스
탈 쉴 슈타우버
Original Assignee
쉔카르 엔지니어링 디자인 아트
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Application filed by 쉔카르 엔지니어링 디자인 아트 filed Critical 쉔카르 엔지니어링 디자인 아트
Publication of KR20190082197A publication Critical patent/KR20190082197A/ko
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04—Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • A61K35/06—Mineral oils, e.g. paraffinic oils or aromatic oils based on aromatic hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
KR1020197009734A 2016-09-11 2017-09-11 미소 구체 및 그 제조 방법 Abandoned KR20190082197A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662393033P 2016-09-11 2016-09-11
US62/393,033 2016-09-11
US201762556459P 2017-09-10 2017-09-10
US62/556,459 2017-09-10
PCT/IL2017/051022 WO2018047185A1 (en) 2016-09-11 2017-09-11 Microspheres and method for producing them

Publications (1)

Publication Number Publication Date
KR20190082197A true KR20190082197A (ko) 2019-07-09

Family

ID=61562719

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020197009734A Abandoned KR20190082197A (ko) 2016-09-11 2017-09-11 미소 구체 및 그 제조 방법

Country Status (10)

Country Link
US (2) US10967346B2 (https=)
EP (1) EP3509763A4 (https=)
JP (1) JP2019529545A (https=)
KR (1) KR20190082197A (https=)
CN (1) CN110494228A (https=)
AU (1) AU2017325041A1 (https=)
CA (1) CA3036271A1 (https=)
IL (1) IL265264A (https=)
SG (1) SG10202102517XA (https=)
WO (1) WO2018047185A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190082197A (ko) * 2016-09-11 2019-07-09 쉔카르 엔지니어링 디자인 아트 미소 구체 및 그 제조 방법
EP3943530A4 (en) * 2019-03-18 2022-10-26 Daicel Corporation CELLULOSIC ACETATE PARTICLES, COSMETIC COMPOSITION AND PROCESS FOR PRODUCTION OF CELLULOSIC ACETATE PARTICLES
CN110721636A (zh) * 2019-11-20 2020-01-24 河南天纳图实业有限公司 微囊包被颗粒类药物的热熔法制粒系统
CN111632563A (zh) * 2020-05-21 2020-09-08 扬州大学 基于微流控技术的水凝胶微球及其制备方法
CN112939611A (zh) * 2021-01-28 2021-06-11 中国船舶重工集团公司第七二五研究所 一种采用直接滴定成型技术制备陶瓷微球的方法
CN113307635A (zh) * 2021-05-24 2021-08-27 中国船舶重工集团公司第七二五研究所 一种通过轨道的凝胶注模直接滴定成型陶瓷微球的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504090A (ja) 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
CA2507769C (en) * 2002-11-27 2013-10-01 Kobo Products, Inc. Density-controlled particulate suspensions for foodstuff, cosmetic, pharmaceutical and other uses
US8652529B2 (en) 2005-11-10 2014-02-18 Flamel Technologies Anti-misuse microparticulate oral pharmaceutical form
GB0711952D0 (en) 2007-06-20 2007-08-01 King S College London Microspheres
US20140147510A1 (en) * 2010-10-28 2014-05-29 The Regents Of The University Of Michigan Multiphasic polymeric particles capable of shape-shifting via environmental stimulation
US9102081B2 (en) * 2011-11-21 2015-08-11 Dr. Hielscher Gmbh Method and apparatus for generating particles
MX2015000119A (es) * 2012-06-25 2015-04-14 Ross Technology Corp Recubrimientos elastoméricos con propiedades hidrofóbicas y/u oleofóbicas.
EP2767332A1 (en) * 2013-02-14 2014-08-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process and device for particle synthesis on a superamphiphobic or superoleophobic surface
JP6328149B2 (ja) 2013-02-25 2018-05-23 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 粒状マイクロカプセル組成物
WO2015081310A1 (en) 2013-11-27 2015-06-04 Trustees Of Boston University Stretch release drug delivery materials
JP2016087479A (ja) * 2014-10-29 2016-05-23 国立大学法人 鹿児島大学 微小カプセル又はビーズの製造方法
KR20190082197A (ko) * 2016-09-11 2019-07-09 쉔카르 엔지니어링 디자인 아트 미소 구체 및 그 제조 방법

Also Published As

Publication number Publication date
SG10202102517XA (en) 2021-04-29
EP3509763A1 (en) 2019-07-17
CN110494228A (zh) 2019-11-22
CA3036271A1 (en) 2018-03-15
US20190270060A1 (en) 2019-09-05
JP2019529545A (ja) 2019-10-17
AU2017325041A1 (en) 2019-04-11
WO2018047185A1 (en) 2018-03-15
US10967346B2 (en) 2021-04-06
IL265264A (en) 2019-05-30
US20210260546A1 (en) 2021-08-26
EP3509763A4 (en) 2020-05-27

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