CA3036271A1 - Microspheres and method for producing them - Google Patents

Microspheres and method for producing them Download PDF

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Publication number
CA3036271A1
CA3036271A1 CA3036271A CA3036271A CA3036271A1 CA 3036271 A1 CA3036271 A1 CA 3036271A1 CA 3036271 A CA3036271 A CA 3036271A CA 3036271 A CA3036271 A CA 3036271A CA 3036271 A1 CA3036271 A1 CA 3036271A1
Authority
CA
Canada
Prior art keywords
microspheres
carrier vehicle
less
superoleophobic surface
forming space
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3036271A
Other languages
English (en)
French (fr)
Inventor
Dan Lewitus
Tal Shpigel Shtauber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenkar Engineering Design Art
Original Assignee
Shenkar Engineering Design Art
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenkar Engineering Design Art filed Critical Shenkar Engineering Design Art
Publication of CA3036271A1 publication Critical patent/CA3036271A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5063—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04—Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • A61K35/06—Mineral oils, e.g. paraffinic oils or aromatic oils based on aromatic hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
    • B01J2/06—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a liquid medium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
CA3036271A 2016-09-11 2017-09-11 Microspheres and method for producing them Pending CA3036271A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662393033P 2016-09-11 2016-09-11
US62/393,033 2016-09-11
US201762556459P 2017-09-10 2017-09-10
US62/556,459 2017-09-10
PCT/IL2017/051022 WO2018047185A1 (en) 2016-09-11 2017-09-11 Microspheres and method for producing them

Publications (1)

Publication Number Publication Date
CA3036271A1 true CA3036271A1 (en) 2018-03-15

Family

ID=61562719

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3036271A Pending CA3036271A1 (en) 2016-09-11 2017-09-11 Microspheres and method for producing them

Country Status (10)

Country Link
US (2) US10967346B2 (https=)
EP (1) EP3509763A4 (https=)
JP (1) JP2019529545A (https=)
KR (1) KR20190082197A (https=)
CN (1) CN110494228A (https=)
AU (1) AU2017325041A1 (https=)
CA (1) CA3036271A1 (https=)
IL (1) IL265264A (https=)
SG (1) SG10202102517XA (https=)
WO (1) WO2018047185A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20190082197A (ko) * 2016-09-11 2019-07-09 쉔카르 엔지니어링 디자인 아트 미소 구체 및 그 제조 방법
EP3943530A4 (en) * 2019-03-18 2022-10-26 Daicel Corporation CELLULOSIC ACETATE PARTICLES, COSMETIC COMPOSITION AND PROCESS FOR PRODUCTION OF CELLULOSIC ACETATE PARTICLES
CN110721636A (zh) * 2019-11-20 2020-01-24 河南天纳图实业有限公司 微囊包被颗粒类药物的热熔法制粒系统
CN111632563A (zh) * 2020-05-21 2020-09-08 扬州大学 基于微流控技术的水凝胶微球及其制备方法
CN112939611A (zh) * 2021-01-28 2021-06-11 中国船舶重工集团公司第七二五研究所 一种采用直接滴定成型技术制备陶瓷微球的方法
CN113307635A (zh) * 2021-05-24 2021-08-27 中国船舶重工集团公司第七二五研究所 一种通过轨道的凝胶注模直接滴定成型陶瓷微球的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005504090A (ja) 2001-09-26 2005-02-10 バクスター・インターナショナル・インコーポレイテッド 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製
CA2507769C (en) * 2002-11-27 2013-10-01 Kobo Products, Inc. Density-controlled particulate suspensions for foodstuff, cosmetic, pharmaceutical and other uses
US8652529B2 (en) 2005-11-10 2014-02-18 Flamel Technologies Anti-misuse microparticulate oral pharmaceutical form
GB0711952D0 (en) 2007-06-20 2007-08-01 King S College London Microspheres
US20140147510A1 (en) * 2010-10-28 2014-05-29 The Regents Of The University Of Michigan Multiphasic polymeric particles capable of shape-shifting via environmental stimulation
US9102081B2 (en) * 2011-11-21 2015-08-11 Dr. Hielscher Gmbh Method and apparatus for generating particles
MX2015000119A (es) * 2012-06-25 2015-04-14 Ross Technology Corp Recubrimientos elastoméricos con propiedades hidrofóbicas y/u oleofóbicas.
EP2767332A1 (en) * 2013-02-14 2014-08-20 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Process and device for particle synthesis on a superamphiphobic or superoleophobic surface
JP6328149B2 (ja) 2013-02-25 2018-05-23 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 粒状マイクロカプセル組成物
WO2015081310A1 (en) 2013-11-27 2015-06-04 Trustees Of Boston University Stretch release drug delivery materials
JP2016087479A (ja) * 2014-10-29 2016-05-23 国立大学法人 鹿児島大学 微小カプセル又はビーズの製造方法
KR20190082197A (ko) * 2016-09-11 2019-07-09 쉔카르 엔지니어링 디자인 아트 미소 구체 및 그 제조 방법

Also Published As

Publication number Publication date
SG10202102517XA (en) 2021-04-29
EP3509763A1 (en) 2019-07-17
CN110494228A (zh) 2019-11-22
US20190270060A1 (en) 2019-09-05
JP2019529545A (ja) 2019-10-17
AU2017325041A1 (en) 2019-04-11
WO2018047185A1 (en) 2018-03-15
US10967346B2 (en) 2021-04-06
IL265264A (en) 2019-05-30
KR20190082197A (ko) 2019-07-09
US20210260546A1 (en) 2021-08-26
EP3509763A4 (en) 2020-05-27

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Effective date: 20220912