KR20190038567A - 키메라 항원 수용체 - Google Patents
키메라 항원 수용체 Download PDFInfo
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- KR20190038567A KR20190038567A KR1020197004478A KR20197004478A KR20190038567A KR 20190038567 A KR20190038567 A KR 20190038567A KR 1020197004478 A KR1020197004478 A KR 1020197004478A KR 20197004478 A KR20197004478 A KR 20197004478A KR 20190038567 A KR20190038567 A KR 20190038567A
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| US20070087005A1 (en) | 2005-10-14 | 2007-04-19 | Lazar Gregory A | Anti-glypican-3 antibody |
| HRP20110620T1 (hr) | 2007-04-04 | 2011-09-30 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | PROTUTIJELO PROTIV EpCAM I NJEGOVE UPOTREBE |
| JP5868593B2 (ja) | 2007-07-17 | 2016-02-24 | メダレックス・リミテッド・ライアビリティ・カンパニーMedarex, L.L.C. | Glypican−3に対するモノクローナル抗体 |
| GB0909904D0 (en) | 2009-06-09 | 2009-07-22 | Affitech As | Product |
| EP2483301A1 (en) | 2009-10-01 | 2012-08-08 | The United States Of America, As Represented By The Secretary, Department of Health and Human Services | Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer |
| US20110165161A1 (en) | 2009-12-23 | 2011-07-07 | Shih-Yao Lin | Anti-epcam antibodies that induce apoptosis of cancer cells and methods using same |
| ES2754394T3 (es) | 2010-09-08 | 2020-04-17 | Chemotherapeutisches Forschungsinstitut Georg Speyer Haus | Receptores de antígenos quiméricos con una región bisagra optimizada |
| EP2998320B1 (en) | 2011-04-19 | 2018-07-18 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Human monoclonal antibodies specific for glypican-3 and use thereof |
| WO2012153186A2 (en) | 2011-05-06 | 2012-11-15 | Kalgene Pharmaceuticals Inc. | Monoclonal antibodies to epcam-icd and methods for detecting epithelial cancer cells |
| US20140322216A1 (en) | 2011-11-08 | 2014-10-30 | The Trustees Of The University Of Pennsylvania | Glypican-3-specific antibody and uses thereof |
| TWI485161B (zh) | 2012-03-02 | 2015-05-21 | Academia Sinica | 抗上皮細胞黏著分子(EpCAM)抗體及其使用方法 |
| WO2013174783A1 (en) | 2012-05-23 | 2013-11-28 | Pieris Ag | Lipocalin muteins with binding-affinity for glypican-3 (gpc-3) and use of lipocalin muteins for target-specific delivery to cells expressing gpc-3 |
| KR102159773B1 (ko) | 2012-06-01 | 2020-09-28 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 글리피칸-3에 대한 고친화력 단클론 항체 및 이의 용도 |
| CN104140974B (zh) | 2013-05-08 | 2017-09-29 | 科济生物医药(上海)有限公司 | 编码gpc‑3嵌合抗原受体蛋白的核酸及表达gpc‑3嵌合抗原受体蛋白的t淋巴细胞 |
| MX2016004239A (es) | 2013-10-02 | 2016-11-14 | Viventia Bio Inc | Anticuerpos anti-epcam y métodos de uso. |
| EP3593812A3 (en) * | 2014-03-15 | 2020-05-27 | Novartis AG | Treatment of cancer using chimeric antigen receptor |
| EP3811970A1 (en) * | 2014-03-15 | 2021-04-28 | Novartis AG | Regulatable chimeric antigen receptor |
| JP6831777B2 (ja) * | 2014-07-21 | 2021-02-17 | ノバルティス アーゲー | Cd33キメラ抗原受容体を使用する癌の処置 |
| JP7054622B2 (ja) * | 2014-07-21 | 2022-04-14 | ノバルティス アーゲー | ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置 |
| WO2016019300A1 (en) * | 2014-07-31 | 2016-02-04 | Novartis Ag | Subset-optimized chimeric antigen receptor-containing t-cells |
| WO2016028896A1 (en) * | 2014-08-19 | 2016-02-25 | Novartis Ag | Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment |
| US10093746B2 (en) | 2014-09-04 | 2018-10-09 | The Trustees Of The University Of Pennsylvania | Glypican-3 antibody and uses thereof |
| DE20196219T1 (de) | 2014-09-26 | 2021-10-28 | Baylor College Of Medicine | Glypican-3-Spezifische Chimäre Antigenrezeptoren für adoptive Immuntherapie |
| US11459390B2 (en) * | 2015-01-16 | 2022-10-04 | Novartis Ag | Phosphoglycerate kinase 1 (PGK) promoters and methods of use for expressing chimeric antigen receptor |
-
2017
- 2017-07-24 SG SG11201900634VA patent/SG11201900634VA/en unknown
- 2017-07-24 CN CN201780059507.6A patent/CN110035768A/zh active Pending
- 2017-07-24 AU AU2017301826A patent/AU2017301826A1/en not_active Abandoned
- 2017-07-24 KR KR1020197004478A patent/KR20190038567A/ko not_active Ceased
- 2017-07-24 EP EP17749637.9A patent/EP3490589A1/en not_active Withdrawn
- 2017-07-24 WO PCT/EP2017/068654 patent/WO2018019772A1/en not_active Ceased
- 2017-07-24 CA CA3031846A patent/CA3031846A1/en not_active Abandoned
- 2017-07-24 US US16/320,055 patent/US20190262397A1/en not_active Abandoned
- 2017-07-24 JP JP2019504106A patent/JP2019530431A/ja not_active Withdrawn
- 2017-07-25 TW TW106124862A patent/TW201806969A/zh unknown
Also Published As
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|---|---|
| CA3031846A1 (en) | 2018-02-01 |
| SG11201900634VA (en) | 2019-02-27 |
| WO2018019772A1 (en) | 2018-02-01 |
| TW201806969A (zh) | 2018-03-01 |
| CN110035768A (zh) | 2019-07-19 |
| US20190262397A1 (en) | 2019-08-29 |
| AU2017301826A1 (en) | 2019-03-14 |
| EP3490589A1 (en) | 2019-06-05 |
| JP2019530431A (ja) | 2019-10-24 |
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