KR20190022476A - 화합물의 국소 도포용 조성물 - Google Patents

화합물의 국소 도포용 조성물 Download PDF

Info

Publication number
KR20190022476A
KR20190022476A KR1020187032806A KR20187032806A KR20190022476A KR 20190022476 A KR20190022476 A KR 20190022476A KR 1020187032806 A KR1020187032806 A KR 1020187032806A KR 20187032806 A KR20187032806 A KR 20187032806A KR 20190022476 A KR20190022476 A KR 20190022476A
Authority
KR
South Korea
Prior art keywords
extract
composition
decoy
acid
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020187032806A
Other languages
English (en)
Korean (ko)
Inventor
제이콥 워
Original Assignee
일루스트리스 파마슈티컬즈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 일루스트리스 파마슈티컬즈 인코포레이티드 filed Critical 일루스트리스 파마슈티컬즈 인코포레이티드
Publication of KR20190022476A publication Critical patent/KR20190022476A/ko
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/624—Coated by macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020187032806A 2016-04-12 2017-04-12 화합물의 국소 도포용 조성물 Ceased KR20190022476A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662321626P 2016-04-12 2016-04-12
US62/321,626 2016-04-12
PCT/US2017/027275 WO2017180788A1 (en) 2016-04-12 2017-04-12 Compositions for topical application of compounds

Publications (1)

Publication Number Publication Date
KR20190022476A true KR20190022476A (ko) 2019-03-06

Family

ID=59999163

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187032806A Ceased KR20190022476A (ko) 2016-04-12 2017-04-12 화합물의 국소 도포용 조성물

Country Status (11)

Country Link
US (2) US20170290778A1 (cg-RX-API-DMAC7.html)
EP (1) EP3442488A4 (cg-RX-API-DMAC7.html)
JP (1) JP2019513799A (cg-RX-API-DMAC7.html)
KR (1) KR20190022476A (cg-RX-API-DMAC7.html)
CN (1) CN109152702A (cg-RX-API-DMAC7.html)
AU (1) AU2017250267A1 (cg-RX-API-DMAC7.html)
CA (1) CA3020400A1 (cg-RX-API-DMAC7.html)
IL (1) IL262180B2 (cg-RX-API-DMAC7.html)
MX (1) MX2018012486A (cg-RX-API-DMAC7.html)
SG (1) SG11201808990QA (cg-RX-API-DMAC7.html)
WO (1) WO2017180788A1 (cg-RX-API-DMAC7.html)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US9180081B2 (en) * 2005-03-03 2015-11-10 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
MX366344B (es) * 2009-06-25 2019-07-05 Revance Therapeutics Inc Formulaciones de toxina botulinica libres de albumina.
WO2011013009A2 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US8871184B2 (en) 2009-10-02 2014-10-28 Foamix Ltd. Topical tetracycline compositions
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
PL3432916T3 (pl) 2016-09-13 2020-04-30 Allergan, Inc. Niebiałkowo stabilzowane kompozycje toksyny clostridium
US11040090B2 (en) * 2016-12-08 2021-06-22 Prime Bio, Inc Botulinum neurotoxin compositions
SG11202003229RA (en) * 2017-10-11 2020-05-28 Illustris Pharmaceuticals Inc Methods and compositions for topical delivery
KR20250057155A (ko) 2017-12-15 2025-04-28 타르서스 파마수티칼스, 아이엔씨. 안검염을 치료하기 위한 이속사졸린 구충제 제제 및 방법
KR102189632B1 (ko) * 2018-03-09 2020-12-11 전남대학교산학협력단 신규 균주 페니실리움 애시둠 및 이의 용도
KR101899413B1 (ko) * 2018-05-03 2018-09-18 주식회사 케어사이드 피부 감염의 예방 또는 치료용 조성물
WO2020004234A1 (ja) 2018-06-26 2020-01-02 久光製薬株式会社 マイクロニードルデバイス及びそれを製造する方法
KR102088104B1 (ko) * 2018-06-29 2020-03-11 호서대학교 산학협력단 개망초 꽃 에센셜 오일을 포함하는 신경 근육 관련 질환 예방 및 치료용 조성물
WO2020087031A1 (en) 2018-10-26 2020-04-30 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
US12502377B2 (en) 2019-04-04 2025-12-23 Tarsus Pharmaceuticals, Inc. Method of eradicating ticks that attach to humans using lotilaner formulations
CN111825775B (zh) * 2019-04-18 2021-11-02 复旦大学 密枝圆柏多糖及其制备方法和在制备抗肿瘤药物中的用途
CN110090193B (zh) * 2019-05-14 2022-04-12 东方爱堡(北京)母婴健康科技有限公司 一种具有减脂功效的祛痘保湿精华液及其制备方法
US20210000910A1 (en) 2019-07-03 2021-01-07 Jysk Skin Solutions Pte Ltd Topical compositions
JP2023509352A (ja) * 2019-12-24 2023-03-08 ダイブ バイオサイエンシーズ，インク． 乾癬及び他の病気を治療するための、局所用シクロスポリン
CN111281980B (zh) * 2020-02-05 2025-01-24 芽米科技(广州)有限公司 一种水溶性γ-聚谷氨酸-替米考星复合物及其制备方法
CN111110831B (zh) * 2020-02-20 2023-08-08 柳州市工人医院 一种溃疡糊剂及其制备方法
CN111297884B (zh) * 2020-04-02 2021-03-30 中国农业科学院蜜蜂研究所 腺苷在蜜蜂病毒感染防治中的应用
CN111329846A (zh) * 2020-04-24 2020-06-26 云南伦扬科技有限公司 一种阴道杀菌贴膜及其制备方法
CN111587861A (zh) * 2020-05-21 2020-08-28 广州市穗升有害生物防治中心 引诱箱
US20230240992A9 (en) * 2020-08-10 2023-08-03 Ziropa, Inc. Compositions and methods for topical delivery
AU2021472120A1 (en) * 2020-09-29 2023-06-15 Relieve Therapeutics Pte. Ltd. Compositions and methods for pain relief and numbing
CA3199093A1 (en) * 2020-10-22 2022-04-28 Pfizer Inc. Peg-free aqueous suspensions for parenteral administration of a corticosteroid
CN114617974B (zh) * 2020-12-10 2023-10-03 中国科学院苏州纳米技术与纳米仿生研究所 一种多肽白蛋白纳米粒及其制备方法和应用
HU231397B1 (hu) 2021-01-22 2023-06-28 Egis Gyógyszergyár Zrt. Pregabalint tartalmazó topikális gyógyszerkészítmény
US20240082191A1 (en) 2021-01-22 2024-03-14 Egis Gyógyszergyár Zrt. Topical formulation containing modified phospholipid compounds
JP2024506865A (ja) * 2021-02-05 2024-02-15 モダン メドウ，インコーポレイテッド スキンケア組成物及びその使用方法
WO2022232161A1 (en) * 2021-04-26 2022-11-03 Sypherion, Llc Inhibitors of nsp1 for treatment of sars-cov-2
CN113332238A (zh) * 2021-06-09 2021-09-03 四川恒通动保生物科技有限公司 一种加米霉素的复合溶液剂的制备方法
JP7141025B1 (ja) 2021-11-11 2022-09-22 エルデシエロ プライベート リミテッド 化合物、組成物、方法、及び製造方法
WO2023119230A1 (en) 2021-12-22 2023-06-29 L'oreal Coagulation pathway and nicotinamide-adenine dinucleotide pathway modulating compositions and methods of their use
CN117186177B (zh) * 2022-05-31 2024-08-23 中国农业大学 一种具有降尿酸活性的鸭血球蛋白肽及其制备方法
US12083204B2 (en) 2022-06-02 2024-09-10 L'oreal Topical composition for homeostatic delivery of nitric oxide and uses thereof
WO2024007014A2 (en) * 2022-06-30 2024-01-04 Board Of Trustees Of The University Of Arkansas Process for treating livestock exposed to toxic forage using melatonin compositions
US12059430B2 (en) 2022-09-29 2024-08-13 Adora Animal Health Corporation Storage stable formulations of sulfated glycosaminoglycans and fragments derived therefrom for the treatment of pain and other medical conditions
CN116098882A (zh) * 2023-04-06 2023-05-12 山东诚创蓝海医药科技有限公司 一种含利多卡因丙胺卡因的组合物及其制备方法
CN116870001B (zh) * 2023-08-11 2024-08-27 云南中医药大学 吲哚-3-甲酸衍生物与氟康唑联合在制备抗耐药白念珠菌药物中的应用
CN117427027B (zh) * 2023-12-21 2024-04-23 舒芙雅生物科技有限公司 一种祛痘组合物及其制备方法
US12357725B1 (en) 2024-05-30 2025-07-15 King Saud University Clinical dressing loaded with coffee extract
CN120284984B (zh) * 2025-04-25 2025-10-17 首都医科大学附属北京胸科医院 一种抗结核分枝杆菌感染的化合物及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234914A (en) * 1991-06-11 1993-08-10 Patent Biopharmaceutics, Inc. Methods of treating hemorrhoids and anorecial disease
IT1260148B (it) * 1992-04-17 1996-03-28 Fidia Spa Impiego di preparazioni di acido ialuronico per la formazione di tessuto osseo
US8728510B1 (en) * 2002-03-15 2014-05-20 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing a bioadhesive material
US7956180B2 (en) * 2004-05-27 2011-06-07 Novozymes A/S Dried and agglomerated hyaluronic acid product
EP1819373A2 (en) * 2004-12-07 2007-08-22 SurModics, Inc. Coatings with crystallized active agent(s)
US7727537B2 (en) * 2005-02-14 2010-06-01 Dpm Therapeutics Corp. Stabilized compositions for topical administration and methods of making same
CA2876767C (en) * 2005-10-03 2018-07-10 Mark A. Pinsky Liposomes comprising hyaluronic acid and their use in improved skin care
AU2006352358B2 (en) * 2006-12-26 2014-03-13 Bomi Patel Framroze Skin lightening composition for hyperpigmented skin
US20100272697A1 (en) * 2007-04-10 2010-10-28 Ali Naji Pancreatic islet cells composition and methods
JP5261680B2 (ja) * 2007-08-09 2013-08-14 キッコーマンバイオケミファ株式会社 ヒアルロン酸プロピレングリコールエステルおよびそれを用いた皮膚外用剤
DE102008034265A1 (de) * 2008-07-22 2010-01-28 Beiersdorf Ag Wirkstoffkombination aus Anisfruchtextrakt und Hyaluronsäure
US8852637B2 (en) * 2008-11-14 2014-10-07 Histogen, Inc. Extracellular matrix compositions for the treatment of cancer
US8679470B2 (en) * 2008-11-28 2014-03-25 Luromed Llc Composition using cross-linked hyaluronic acid for topical cosmetic and therapeutic applications
US8980243B2 (en) * 2009-05-19 2015-03-17 Neal Koller Surface active agent compositions and methods for enhancing oxygenation, reducing bacteria and improving wound healing at a site of treatment
AU2010249805B2 (en) * 2009-05-20 2015-06-11 Humacyte, Inc. Elastin for soft tissue augmentation
CA2703532C (en) * 2010-05-10 2018-05-01 Eva Turley Topically administered, skin-penetrating glycosaminoglycan formulations suitable for use in cosmetic and pharmaceutical applications
US20110305737A1 (en) * 2010-06-09 2011-12-15 NY Derm LLC Multi-Active Microtargeted Anti-Aging Skin Cream Polymer Technology
FR2971711B1 (fr) * 2011-02-18 2014-06-13 Isp Investments Inc Composition cosmetique comprenant un extrait de petit epeautre en tant qu'agent activateur de la synthese des proteines de la matrice extracellulaire
EP2961946B1 (en) * 2013-02-28 2020-04-29 United Technologies Corporation Method and apparatus for selectively collecting pre-diffuser airflow
US20160000834A1 (en) * 2013-02-28 2016-01-07 Ventrix, Inc. Methods and compositions for tissue therapy and analysis
US10111801B2 (en) * 2013-03-05 2018-10-30 Dante Liberatoscioli Apparatus for relieving back pain

Also Published As

Publication number Publication date
EP3442488A1 (en) 2019-02-20
IL262180A (en) 2018-11-29
IL262180B2 (en) 2025-12-01
US20170290778A1 (en) 2017-10-12
CA3020400A1 (en) 2017-10-19
CN109152702A (zh) 2019-01-04
SG11201808990QA (en) 2018-11-29
JP2019513799A (ja) 2019-05-30
EP3442488A4 (en) 2020-03-25
US20190008795A1 (en) 2019-01-10
IL262180B1 (en) 2025-08-01
WO2017180788A1 (en) 2017-10-19
MX2018012486A (es) 2019-06-06
AU2017250267A1 (en) 2018-11-08

Similar Documents

Publication Publication Date Title
KR20190022476A (ko) 화합물의 국소 도포용 조성물
AU2018347514C1 (en) Methods and compositions for topical delivery
JP6337071B2 (ja) 皮膚外用剤組成物
JP2013516482A (ja) 局所経皮用デクスメデトミジン組成物およびそれらの使用方法
CN101453985A (zh) 促进毛发生长的组合物
Akram et al. Design and development of insulin emulgel formulation for transdermal drug delivery and its evaluation
EP2849566B1 (en) Adenosine analogues for the treatment of pain
EP3677264A1 (en) Composition for preventing or treating atopic dermatitis
CN113056268A (zh) 纤溶酶原激活物抑制剂1(pai-1)抑制剂和其用途
US20170232059A1 (en) Composition comprising oxytocin
KR20070054222A (ko) 진통 작용이 있는 약제 조성물
JP7190571B2 (ja) ブレイアコニチンａの用途
CN101785753B (zh) 一种治疗中枢神经系统疾病的天麻苷元透皮凝胶剂
US9744156B2 (en) Methods and compositions for enhanced transungual delivery of AR-12
US20130203809A1 (en) Pharmaceutical compositions comprising 7-(1h-imidazol-4-ylmethyl)-5,6,7,8-tetrahydro-quinoline for treating skin diseases and conditions
JP2024544965A (ja) 深部皮膚薬物送達のためのスピロノラクトンの医薬組成物
US10004734B2 (en) Compositions and methods for treating rebound erythema associated with topical alpha-adrenergic agonists
CN116966129A (zh) 稳定的局部用非诺多泮组合物
US20210121431A1 (en) Novel compositions and methods for treating cutaneous ulcers and non-healing cutaneous wounds using nitric oxide-donating prostaglandin f-2 -alpha analogs
JP6016085B2 (ja) 抗真菌外用組成物及び抗真菌外用組成物の適用方法
CN116710067A (zh) 用于深层皮肤药物递送的组合物和方法
Abd-ElGawad et al. Effect of Penetration Enhancers on the Permeability of Ketoconazole Gels Through Rabbit Skin
HK40055571A (en) Plasminogen activator inhibitor 1 (pai-1) inhibitors and uses therefor
Buensalido et al. The efficacy and safety of 1.5% Carica papaya latex cream compared to 2% ketoconazole cream and vehicle in the treatment of tinea corporis: A randomized, double blind, controlled trial

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20181112

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
A201 Request for examination
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20200408

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20210526

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 20211124

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 20210526

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I