KR20190012642A - Cosmetic Composition Comprising Extract of Alpinia oxyphylla Miquel As Active Ingredient - Google Patents

Abstract

The present invention relates to a cosmetic composition containing an Alpinia oxyphylla Miquel extract as an active ingredient. Specifically, the present invention relates to a cosmetic composition useful as cosmetic material for accelerating differentiation of keratinocytes, restoring skin barrier function, and moisturizing skin using the extract of Alpinia oxyphylla Miquel as an active ingredient.

Description

[0002] Cosmetic Composition Comprising Extract of Alpinia oxyphylla Miquel As Active Ingredient [

TECHNICAL FIELD The present invention relates to a cosmetic composition containing an extract of Raw Millet as an active ingredient.

The skin, which plays an important role as a barrier to protect the living body from temperature, ultraviolet rays and physical and chemical external environment, is divided into three layers such as epidermis, dermis and subcutaneous tissue in order from the topmost layer. Among them, the epidermis plays an important role in preventing water evaporation of the human body.

The epidermis is composed of the basal layer, the superficial layer, the granular layer and the stratum corneum. The stratum corneum is composed of keratinocyte and intercellular lipids. The cells in the stratum corneum act like bricks. The intercellular lipids in keratinocytes act like mortars. (J. Invest. Dermatol. 80 (Suppl.), 44-49, 1983). The skin barrier of the stratum corneum is composed of ceramide, fatty acid and cholesterol, and it inhibits penetration of foreign substances and prevents the transepidermal water loss (TEWL). In addition, there is a high concentration of Natural Moisturing Factor (NMF) in the keratinocyte of a healthy person to help the moisture retention of the skin. For example, a substance such as amino acid is water-soluble, . (J. Invest., Dermatol., 54, 24-31, 1970)

As the age of a person increases, the tendency of the skin to dry is observed. Physiologically, the physiological view is that the removal time of the stratum corneum is prolonged, the lipid synthesis ability of the epidermal cell is decreased, and the amount of moisturizing factor and lipid in the stratum corneum . This is because the normal differentiation process did not occur in the epidermal cells due to the deterioration of the skin barrier function and the dryness of the skin due to hyperkeratosis as the age increases. Therefore, by promoting the differentiation of keratinocytes, it is possible to induce strengthening of skin barrier, thereby enhancing skin moisture retaining function and protection function from external environment.

Skin moisturization is essential for preventing skin moisture retention and environmental diseases from external environment. In the past, Humectant, which has a property of absorbing moisture as a humectant, and occlusive moisturizer, which prevents evaporation of water, Has been used to increase the moisture retention in the stratum corneum. Huygerminton is a substance such as glycerin, propylene glycol, 1,3-butyleneglycol, polyethylene glycol, sorbitol, 2-pyrrolidone-5-carboxylate and the like. It has the disadvantage of feeling severe or damp. (5), 731-740, 1944), it is difficult to maintain the stability of emulsified formulations, and a transparent gel phase There is a disadvantage that it is not suitable for manufacturing a product.

Recently, many cosmetic products using natural products have been developed to reduce skin irritation caused by various chemical substances and the like. Natural materials are not only less harmful to the skin, but also have increased their value as a raw material for cosmetics due to the recent popularity of cosmetics using natural materials.

Korean Patent Registration No. 10-0515419 discloses a cosmetic composition for exhibiting whitening effect by containing extract of natural herb medicine obtained from cabbage, raw fish root, bean jugular, and sulfur in a conventional cosmetic composition.

Korean Patent Laid-Open Publication No. 2011-0102682 also discloses a liquid eye patch cosmetic composition containing a core improving agent or an anti-aging substance, and includes a substance extracted from a natural product.

The inventors of the present invention have studied the possibility of applying various natural products to cosmetics. As a result, the present inventors selected the raw materials and prepared extracts from them to measure the differentiation of skin keratinocyte, recovery of skin barrier function and moisturizing effect As a result, it was found that the efficacy of cosmetics can be expected because the efficacy is very excellent.

It is an object of the present invention to provide a cosmetic composition which contains a raw extract to promote differentiation of dermal keratinocytes, restoration of skin barrier function and moisturizing effect.

It is another object of the present invention to provide a cosmetic composition which exhibits an efficacy effect through solvent extraction, supercritical extraction, ultrasonic extraction, and purification in order to maximize the efficacy of the raw extract.

Therefore, the object of the present invention as described above is achieved by a cosmetic composition for skin moisturizing which contains an extract of rice muslin as an active ingredient.

Preferably, the cosmetic composition is for promoting differentiation of keratinocytes.

Preferably, the cosmetic composition is characterized in that it is for recovering skin barrier function.

The cosmetic composition is characterized by being contained in an amount of 0.001 to 30.0% by weight based on the total weight of the cosmetic composition.

Preferably, the raw extract is selected from the group consisting of water, an anhydrous or a lower alcohol having 1 to 4 carbon atoms, propylene glycol, butylene glycol, glycerin, acetone, ethyl acetate, chloroform, butyl acetate, diethyl ether, dichloromethane, And a mixture thereof. The solvent extraction method, the supercritical extraction method, or the ultrasonic extraction method is used.

Preferably, the cosmetic composition is selected from the group consisting of solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, cleansing oils, powder foundations, emulsion foundations, wax foundations and sprays And has a formulation.

The raw extract according to the present invention has a skin keratinocyte differentiation promoting effect, a moisturizing effect and a skin barrier function restoring effect. In addition, in order to maximize the efficacy of the raw extracts, solvent extraction, supersonic extraction, and supercritical extraction are used to further promote the differentiation of skin keratinocyte, recovery of skin barrier function and moisturizing effect.

Unless defined otherwise, all technical terms used in the present invention have the following definitions and are consistent with the meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. Also, preferred methods or samples are described in this specification, but similar or equivalent ones are also included in the scope of the present invention.

The present invention relates to a cosmetic composition for moisturizing skin, promoting differentiation of dermal keratinocyte, or for restoring skin barrier function, which contains an extract from raw rape as an active ingredient.

Alpinia oxyphylla Miquel , which is used as an active ingredient in the cosmetic composition of the present invention, is distributed in Korea and all over the world as a fruit of ginger according to the plant classification. It has a spherical to elliptical shape with a pointed tip at both ends, a length of 1 to 2 cm, a diameter of 0.7 ~ 1 cm. The outer surface is brown to dark brown with a number of vertically connected small horn shaped streaks. The fruit skin is 0.03 ~ 0.05cm in thickness and it is hard to peel off with the lump of seed. The inside is a thin membrane divided vertically into three rooms and there are 5 ~ 8 seeds attached to each side by the husk shell. Seeds are brown to dark brown, uneven polyhedra about 0.35cm in diameter and vaginal hard. There is a peculiar smell and the taste is slightly bitter. It is used when the runny nose runs down due to the abdominal bloating caused by weakness of the abdomen, weakness of kidney function, frequent urination, weakness of the stool, nocturnal enuresis during pregnancy, Other names include Ichi-ini, Ichi-ji, and ici-ji.

Raw jars contain sugars, amino acids, minerals, and vitamins. However, at present, only a study on the role as a pharmacologically active plant has been made, and research as a cosmetic composition has been limited.

In the present invention, the raw paper extract is obtained by extracting from the peel, seed and the like of the raw paper, and is preferably an extract obtained from the seed.

The crude extract of the present invention can also be prepared by using conventional solvents known in the art, that is, under the conditions of ordinary temperature and pressure, but preferably water, 1-4 carbon atoms A solvent selected from the group consisting of anhydrous or lower alcohol, propylene glycol, 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform, hexane, Extraction using a solvent extraction method, depressurization using carbon dioxide, supercritical extraction by high temperature, or ultrasonic extraction.

In the present invention, a solvent extraction method using an extraction solvent is preferably used.

In the present invention, Japanese rape extracts can be obtained by various extraction solvents, for example, water, anhydrous or low-boiling alcohols having 1 to 4 carbon atoms, propylene glycol, 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, (V / v) ethanol or water, preferably at least one solvent selected from the group consisting of acetone, dichloromethane, chloroform, hexane, and mixtures thereof, , And most preferably 70% (v / v) ethanol.

It should be apparent to those skilled in the art that the extract of the raw material of the present invention exhibits substantially the same effect not only by the above-mentioned extraction solvent but also by other extraction solvent.

In addition, the raw animal extract of the present invention includes not only the extract obtained by the above-described extraction solvent, but also the extract obtained through ordinary purification and fermentation processes. For example, decomposition by carbon dioxide, extraction by supercritical extraction at high temperature, extraction by extraction using ultrasound, separation by ultrafiltration membrane having a constant molecular weight cut-off value, separation by various chromatography, The extracts of the present invention also include active fractions obtained through various additional purification and extraction methods such as fermentation products using microorganisms.

Further, the present invention provides a cosmetic composition characterized in that the above extract is obtained by liquid-freezing obtained by cold-pressing and heating filtration at room temperature, and further by concentrating or lyophilizing the solvent under reduced pressure.

The supercritical fluid extraction refers to supercritical fluid extraction. Generally, the supercritical fluid is extracted from the liquid and the liquid when the gas reaches the critical point at high temperature and high pressure. (J. Chromatogr. A. 1998; 479: 200-205). In addition, it has been reported that the supercritical fluid has a polarity similar to that of a nonpolar solvent.

Carbon dioxide is a supercritical fluid with both liquid and gaseous nature, with the operation of supercritical fluid equipment reaching its critical pressure and temperature, resulting in increased solubility in fat-soluble solutes. When supercritical carbon dioxide passes through an extraction vessel containing a certain amount of sample, the lipophilic substance contained in the sample is extracted into supercritical carbon dioxide.

When the supernatant carbon dioxide containing a small amount of cosolvent is passed through the sample remaining in the extraction vessel after extracting the lipid-soluble substance, components that were not extracted by pure supercritical carbon dioxide can be extracted.

The supercritical fluid used in the supercritical extraction method of the present invention can effectively extract an active ingredient by using a mixed fluid in which a cosolvent is further mixed with supercritical carbon dioxide or carbon dioxide.

These co-solvents may be used alone or in admixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, hexane and diethyl ether.

Most of the extracted samples contain carbon dioxide. Since the carbon dioxide is volatilized into air at room temperature, the extract obtained by the above method can be used as a cosmetic composition, and the cosolvent can be removed by a reduced pressure evaporator.

In addition, the ultrasonic extraction method is an extraction method using energy generated by ultrasonic vibration. Ultrasonic waves can destroy an insoluble solvent contained in a sample in a water-soluble solvent. Due to the high local temperature, Since the kinetic energy of the reactant particles is increased, sufficient energy required for the reaction is obtained. By inducing the high pressure by the shock effect of the ultrasonic energy, the mixing effect of the substance contained in the sample and the solvent is enhanced, thereby increasing the extraction efficiency.

As the extraction solvent which can be used for the ultrasonic extraction method, one or a mixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, hexane and diethyl ether can be used. The extracted sample is recovered by vacuum filtration, and the filtrate is recovered, and the extract is removed by a vacuum evaporator and freeze-dried to obtain an extract.

According to the present invention, the raw animal extract is contained in an amount of 0.001 to 30.0% by weight based on the total weight of the cosmetic composition, and more preferably, the raw animal extract is contained in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic composition do. When the content of the extract is less than 0.001% by weight, the effect of improving the skin is not exhibited. When the content of the extract is more than 30.0% by weight, the degree of improvement of the skin against the increase of the content is insignificant, It is not even.

Accordingly, the cosmetic composition of the present invention including the raw animal extract having various functions is characterized by having excellent skin keratinocyte differentiation promotion, skin barrier function recovery, and moisturizing effect.

The ingredients contained in the cosmetic composition of the present invention may contain, as an active ingredient, the ingredients commonly used in cosmetic compositions in addition to the above-mentioned effective ingredients, and may contain conventional ingredients such as antioxidants, stabilizers, solubilizers, vitamins, Supplements, and carriers.

The cosmetic composition of the present invention can be prepared into any of the formulations conventionally produced in the art and can be used in the form of solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, , Oil, powdered foundation, emulsion foundation, wax foundation, pack, massage cream and spray, but is not limited thereto. More specifically, it can be manufactured in the form of a soft lotion, a nutritional lotion, a nutritional cream, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray or a powder.

When the formulation of the present invention is a paste, cream or gel, an animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component .

When the formulation of the present invention is a solution or an emulsion, a solvent, a dissolving agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters.

In the case where the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, / Propane or dimethyl ether.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide ether Alkylamido betaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.

When the cosmetic composition of the present invention is a soap, a surfactant-containing cleansing formulation or a surfactant-free cleansing formulation, it may be applied to the skin and then wiped off, washed or rinsed with water. The surfactant-containing cleansing formulation may be a cleansing foam, a cleansing water, a cleansing towel and a cleansing pack. The surfactant-free cleansing formulation may be a cleansing cream, , Cleansing lotion, cleansing water and cleansing gel, but is not limited thereto.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these embodiments are only for describing the present invention in more detail and that the scope of the present invention is not limited by these embodiments in accordance with the gist of the present invention .

Manufacturing example  1: Manufacture of Raw Drug Solvent Extract

After shredding, 200g of the shrubby raw fruit was refluxed with 70% (v / v) aqueous ethanol solution for 5 hours for 3 times, cooled, and filtered through Whatman # 4 filter paper. The filtered extract was washed with an ultrafiltration membrane and concentrated under reduced pressure and freeze-dried at 50 ° C or less to obtain 6.3 g of the extract. Then, the dried rice germ extract powder was dissolved in 1,3-butylene glycol and used.

Manufacturing example  2: raw Supercritical  Preparation of fluid extract

100g of the shrubby shrub was extracted with olive oil as a co-solvent under supercritical conditions at a temperature of 60 ° C and a pressure of 300 atmospheric pressure using a conventional supercritical extraction method. The salt was removed using an ultrafiltration membrane, And lyophilized to obtain 9.8 g of raw paper extract powder. This was dissolved in 1,3-butylene glycol and used.

Manufacturing example  3: Preparation of raw ultrasound extract

200g of the shredded rice gruel was extracted with ultrasonic equipment at 25 ℃ for 2 hours at 30 ℃. After removing the salt by using the ultrafiltration membrane, 6.5g of raw extract powder was obtained by vacuum concentration and freeze drying. . This was dissolved in 1,3-butylene glycol and used.

Formulation Example  1: containing the raw extract Cosmetics  Preparation of composition

Cosmetic preparations containing the raw extracts were prepared in the same manner as in Examples 1, 2 and 3, except that the extracts of Preparation Examples 1 to 3 were prepared in the same manner as in Preparation Examples 1, 2 and 3. For comparison of efficacy, glycerin and 1,3- (Comparative dosage form 1) containing glycerin and sorbitol as a moisturizing agent (comparative dosage form 2), and a cosmetic composition (comparative dosage form 3) containing neither an extract nor a moisturizer were prepared as follows: Table 1 shows the results.

division ingredient Formulation Example 1 Formulation Example 2 Formulation Example 3 compare
Formulation Example 1 compare
Formulation Example 2 compare
Formulation Example 3 A Raw extract
(Production Example 1) 5.0 - - - - Raw extract
(Production Example 2) - 5.0 - - - Raw extract
(Production Example 3) 5.0 glycerin 5.0 5.0 1,3-butylene glycol - - 5.0 - - Sorbitol - - - 5.0 - EDTA-2Na 0.02 0.02 0.02 0.02 0.02 0.02 Purified water to 100 to 100 to 100 to 100 to 100 to 100 B Cetostearyl alcohol 2.0 2.0 2.0 2.0 2.0 2.0 Glyceryl stearate 1.5 1.5 1.5 1.5 1.5 1.5 Microcrystalline 0.7 0.7 0.7 0.7 0.7 0.7 Squalane 5.0 5.0 5.0 5.0 5.0 5.0 Liquid paraffin 3.0 3.0 3.0 3.0 3.0 3.0 Trioctanoin 5.0 5.0 5.0 5.0 5.0 5.0 Polysorbate 1.2 1.2 1.2 1.2 1.2 1.2 Sorbitan stearate 0.5 0.5 0.5 0.5 0.5 0.5 Tocopheryl acetate 0.2 0.2 0.2 0.2 0.2 0.2 Cyclomethicone 3.0 3.0 3.0 3.0 3.0 3.0 BHT 0.05 0.05 0.05 0.05 0.05 0.05 C Incense, preservative Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount

Experimental Example  1: Promotion of keratinocyte differentiation of raw extract

Human keratinocytes were cultured in a culture flask and grown to about 80%. The crude extracts (Preparation Examples 1 to 3) were added at concentrations of 10, 50, 100, and 200 ppm, respectively, After treatment for a day, proteins were dissolved by mixing a urea, a denaturant such as sodium dodecyl sulfate (SDS), and a reducing agent such as? -Mercaptoethanol. After that, the remaining stratum corneum was assayed for absorbance at 310 nm to determine the peptide concentration, and the amount of increase by each sample was compared based on distilled water as a negative control.

Concentration (ppm) Promoting effect of keratinocyte differentiation (%) Production Example 1 Production Example 2 Production Example 3 10 27.11 32.14 29.02 50 48.32 60.78 51.12 100 64.46 79.31 70.36 200 114.97 138.76 131.23 Negative control (distilled water) 0 0 0 Positive control (TGF-β) 10 nM 142.85 142.85 143.25

As shown in the results of Table 2, it can be confirmed that the extract of the raw ripe used in the present invention is excellent in promoting keratinocyte differentiation, and the effect of Preparation Example 2 is the most excellent.

Experimental Example  2: Moisturizing effect of raw extract

The clinical moisturizing effect and the sustaining ability of the cosmetic compositions of Formulation Examples 1, 2 and 3 were measured as follows. A total of 125 healthy male and female adults who felt skin dryness were randomly divided into groups of 25 individuals. Each group was compared with the corresponding formulation and compared with Formulation Example 3 for 2 weeks for 1 week for 2 weeks. Respectively. The moisturizing effect was evaluated by changing the electrical conductivity according to the moisture content of the epidermis using Corneometer CM 820 (Corage + Khazaka, Germany) for 2 weeks from the start of the test. The experimental results are shown in Table 3 below.

division Before use After 2 weeks of use After 4 weeks of use Formulation Example 1 23.5 37.1 42.4 Formulation Example 2 23.4 39.5 45.8 Formulation Example 3 24.1 38.0 44.6 Comparative Formulation Example 1 24.7 35.1 41.0 Comparative Formulation Example 2 25.2 34.9 40.9 Comparative Formulation Example 3 23.3 27.5 31.9

As shown in the above Table 3, the moisturizing effect of the cosmetic compositions (Formulation Examples 1, 2 and 3) containing the crude extract of the present invention, as compared with the cosmetic compositions containing the chemical moisturizing agent (Comparative Formulation Examples 1 and 2) Was better.

Experimental Example  3: Skin barrier improvement effect of raw extract

25 ℃, relative humidity of 45% and 25 healthy women in the room without air flow. Skin barrier damage was induced using a 1% aqueous solution of sodium lauryl sulfate (SLS). After applying the cosmetic composition of Formulations 1, 2 and 3 to the upper arm of the arm, TEWAMETER TM210 (C + K electronic GmhH, Germany) was used to measure the amount of transdermal water loss. That is, TEWL (Transepidermal Water Loss) value was measured by changing the TEWL value with time, thereby confirming the skin barrier recovery rate. The experimental results are shown in Table 4 below.

division Skin barrier recovery rate (%) 2D 4D 6D 8D Formulation Example 1 49.2 61.4 80.6 92.5 Formulation Example 2 51.7 64.8 83.6 94.0 Formulation Example 3 50.8 63.0 82.3 93.2 Comparative Formulation Example 3 40.2 55.8 61.7 71.3

As shown in Table 4, it can be seen that the transdermal water loss was improved as compared to Comparative Formulation Example 3 which did not contain Formulation Examples 1, 2 and 3 dipping extracts containing raw extracts. Further, it can be confirmed that the effect of the formulation example 2 is the most excellent.

Experimental Example  4: Safety test of raw extract

In order to confirm skin irritation on the cosmetic composition of Formulation Examples 1, 2 and 3, a human skin patch test was conducted. Twenty women in their 20s and 30s who have never been hypersensitive to skin irritation due to a history of skin disease or skin allergy have been tested. Comparative Example 3, which does not contain raw extracts, was used as a control.

First, the test area was wiped with 70% ethanol and then dried. The prepared test substance was dripped into a fin chamber (Finn Chamber, 100X10, EPITEST), and then hermetically sealed on the back of the test subject. After 24 hours of exposure, the patches were removed, and 1 hour and 24 hours after the removal of the patch, erythema and edema were observed using a magnifying glass (8MC-150, DAZOR).

The skin reaction was judged according to the rules of the International Contact Dermatitis Research Group (ICDRG) (Table 5). The average skin reactivity was calculated by the following formula (1) and the results are shown in Table 6.

sign score Evaluation standard - 0 No reaction ± 0.5 Faint or mild erythema + One The border is clear but weak erythema, edema and palsy ++ 2 Clear erythema, papules and small follicles +++ 3 Severe erythema and alopecia. Scab formation

division 24 hours 48 hours Average skin response
(n = 20) ± + ++ ± + ++ Formulation Example 1 2 - - - - - 0.27 Formulation Example 2 - - - - - - 0 Formulation Example 3 One - - - - - 0.13 Comparative Formulation Example 3 2 - - - - - 0.27

As shown in Table 6, all of the cosmetic compositions of Formulation Examples 1, 2 and 3 did not cause skin irritation, and it was found that the safety of the cosmetic formulation containing the raw extract was not affected.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the same is by way of illustration and example only and is not to be construed as limiting the scope of the present invention. It is therefore intended that the scope of the invention be defined by the claims appended hereto and their equivalents.

Claims (6)

A cosmetic composition for moisturizing the skin, containing the raw extract as an active ingredient. A cosmetic composition for accelerating the differentiation of keratinocyte cells containing an extract of raw rape as an active ingredient. A cosmetic composition for recovering skin barrier function containing an extract of Rawan japonica as an active ingredient. The cosmetic composition according to any one of claims 1 to 3, wherein the raw animal extract is contained in an amount of 0.001 to 30.0% by weight based on the total weight of the cosmetic composition. The process according to any one of claims 1 to 3, wherein the raw extract is selected from the group consisting of water, an anhydrous or a lower alcohol having 1-4 carbon atoms, propylene glycol, butylene glycol, glycerin, acetone, ethyl acetate, chloroform, Wherein the extract is extracted by an extraction method selected from the group consisting of solvent extraction using supernatant, diethyl ether, dichloromethane, hexane, and mixtures thereof, supercritical extraction or ultrasonic extraction. The cosmetic composition as claimed in any one of claims 1 to 3, wherein the cosmetic composition is an aqueous solution, suspension, emulsion, paste, gel, cream, lotion, powder, soap, surfactant-containing cleansing oil, powder foundation, A liquid foundation, a wax foundation, and a spray.