KR101985380B1 - Cosmetic composition for moisturizing skin comprising extract of tigernuts as active ingredient - Google Patents

Abstract

The present invention relates to a cosmetic composition for moisturizing skin containing an extract of Tiger nuts as an active ingredient and is characterized by containing 0.0001 to 30.0% by weight of Tiger nuts extract as an active ingredient with respect to the total weight of the cosmetic composition. According to the present invention, the cosmetic composition comprising Tiger nuts extract has excellent skin moisturizing effect, skin barrier function improvement, and skin barrier function enhancement effect.

Description

TECHNICAL FIELD The present invention relates to a cosmetic composition for skin moisturizing which contains an extract of Tiger nuts as an active ingredient.

The present invention relates to a cosmetic composition for moisturizing the skin containing an extract of Tiger nuts as an active ingredient. Specifically, the cosmetic composition of the present invention has skin moisturizing effect and skin barrier function improving and strengthening effect.

In general, the skin is an organ that is always in contact with the external environment, and acts as a protective barrier to prevent moisture loss. The stratum corneum is located on the outermost layer of the skin and plays the most important role in skin barrier. The keratin layer inhibits the loss of water and electrolytes outside the skin, thereby preventing the skin from drying out. It also plays an important role in protecting the human body from external physical damage and chemicals, and preventing harmful substances such as bacteria, viruses and fine dust from entering the skin.

The skin barrier consists of dead keratinocyte (intercellular lipid) and intercellular lipids, which keep the skin hydrated and prevent it from permeating to the skin, and function as skin barrier. The main constituents of cell interleukin are ceramide (40 ~ 50%), cholesterol (20 ~ 25%) and free fatty acid (20 ~ 25%). do. The corneocyte envelope, which constitutes the surface of dead keratinocytes, is composed of proteins such as involucrin, loricrin, and filaggrin, which are responsible for the stability of intercellular lipids It plays an important role.

It has been reported that atopic dermatitis and psoriasis symptoms occur when the protective barrier function of the stratum corneum is reduced by aging or genetic factors. The lipid component of the keratinocyte layer, sebum component and epidermal lipid, prevent the loss of moisture, electrolytes, etc. and contain a certain amount of moisture to keep the skin from drying out. A natural moisturizing factor (NMF) such as sodium pyrrolidone carboxylate (PCA-Na), amino acids, sodium lactate, urea, etc. in the stratum corneum is a major determinant of the amount of water in the stratum corneum, It keeps moisture inside. In addition, the intercellular quality composed of ceramide, cholesterol, fatty acid, etc. inhibits the evaporation of water in the body. In addition to the epidermis, the dermis also needs to have a certain amount of water to be preserved. The mucopolysaccharide, such as hyaluronic acid, chondroitin sulfate, dermatan sulfate, heparan sulfate, It plays an important role in moisturizing.

However, due to severe weather, strong ultraviolet rays, excessive use of cleanser, stress and natural skin aging, the skin becomes dry and becomes dry, causing skin wrinkles and elasticity. Therefore, in order to prevent such skin dryness, cosmetics are blended with natural moisturizing factors such as glycerin, sorbitol, 1,3-butylene glycol and propanediol, and sodium pyrrolidonecarboxylate and amino acid, There are problems such as irritation and formulation stability, and studies on natural extracts which are harmless to the human body and are stable are under way.

Korean Patent Laid-Open Publication No. 10-2013-0014321 discloses a cosmetic composition comprising a complex fermented extract of walnuts and chestnuts as an active ingredient, which is excellent in preventing skin aging and improving skin wrinkles.

Accordingly, the inventors of the present invention have studied the applicability of cosmetics to various natural products not yet known. As a result, they found that Tiger nuts extract was superior in moisturizing effect, skin barrier function improvement and strengthening effect, and completed the present invention Respectively.

It is an object of the present invention to provide a cosmetic composition containing Tiger nuts extract and exhibiting skin moisturizing effect, skin barrier function improvement and strengthening effect. It is also an object of the present invention to provide a cosmetic composition which exhibits excellent effects by preparing supercritical and ultrasound extracts and purifying them in order to maximize the efficacy of Tiger nuts extract.

Therefore, the object of the present invention as described above is achieved by a cosmetic composition for skin moisturizing comprising an extract of Tiger nuts as an active ingredient.

Preferably, the cosmetic composition has an effect of enhancing skin barrier function and improving skin barrier function.

Preferably, the Tiger nuts extract is contained in an amount of 0.0001 to 30.0% by weight based on the total weight of the cosmetic composition.

Preferably, the Tiger Nut extract is selected from the group consisting of (a) water, an anhydrous or lower alcohol having 1-4 carbon atoms, propylene glycol, butylene glycol, glycerin, acetone, ethyl acetate, chloroform, butyl acetate, (B) a supercritical extraction method, or (c) an ultrasonic extraction method, in which a solvent extraction method using an extraction solvent selected from the group consisting of dichloromethane, hexane and a mixture thereof is used.

The extract of Tiger nuts according to the present invention has a skin moisturizing effect and a skin barrier function enhancing effect.

Further, according to the present invention, ultrasound extraction or supercritical extraction is performed to maximize the efficacy of the Tiger nuts extract, thereby exhibiting further improved skin moisturizing effect, skin barrier function improvement and strengthening effect.

Unless defined otherwise, all technical terms used in the present invention have the following definitions and are consistent with the meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In addition, preferred methods or samples are described in this specification, but similar or equivalent ones are also included in the scope of the present invention. The contents of all publications referred to herein are incorporated herein by reference.

The cosmetic composition of the present invention contains Tiger nuts extract as an active ingredient.

Tiger nuts are a perennial plant that is made of southern Europe and the Mediterranean Sea. Scientific name is Cyperus esculentus L. It is also called Chufa in Spain and Yellow nutsedge in English and it is also called Earth almond.

Basically, it is a fertile organism. Its quality is determined by soil quality rather than climate. It grows best in sandy soil with moderate water content. The plant grows up to 90cm in height, and the leaves, which grow like elongated weeds, are very rough in texture. In addition, leaves like roasted leaves come out from the roots and have beard roots. In the beard roots there are tubers, or tubers, that run like potatoes and taro. The diameter of each trunk is 3mm ~ 19mm, it is elliptical or circular. Like the peanut bark, there is a black spot on the surface of the texture, which is called 'Tiger nuts'.

In Spain, which is the main product, sowing takes place from April to May, harvesting takes place from November to January. After harvesting, it is cleaned and dried for a maximum of 3 months. When dried, it is yellowish brown with a slight sweetness and smells like almond or hazelnut. In dry condition, sweet potatoes are similar in texture.

Tiger nuts are rich in protein, calcium, iron, potassium, manganese, zinc, and are known to have a high content of oleic acid.

In addition, the Tiger nuts extract of the present invention can be prepared by using conventional solvents known in the art, that is, under the conditions of ordinary temperature and pressure, but preferably using (a) water, (Such as methanol, ethanol, propanol and butanol) having 1 to 4 carbon atoms, propylene glycol, 1,3-butylene glycol, glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloro (B) solvent extraction using a solvent selected from the group consisting of methanol, chloroform, hexane, and mixtures thereof; (b) supercritical extraction with carbon dioxide and supercritical extraction with high temperature; or (c) sonication.

In the present invention, a solvent extraction method using an extraction solvent is preferably used.

In the present invention, the Tiger nuts extract can be obtained by various extraction solvents, for example, water, anhydrous or low-boiling alcohols of 1 to 5 carbon atoms (e.g., methanol, ethanol, propanol and butanol), propylene glycol, And at least one extraction solvent selected from the group consisting of glycerin, acetone, diethyl ether, ethyl acetate, butyl acetate, dichloromethane, chloroform, hexane and mixtures thereof. (v / v) ethanol or water, and most preferably 70% (v / v) ethanol.

On the other hand, it is obvious to those skilled in the art that the extract of Tiger nuts of the present invention can obtain an extract showing substantially the same effect by using not only the above-mentioned extraction solvent but also other extraction solvent.

In addition, the Tiger nuts extract of the present invention includes not only extracts obtained by the above-mentioned extraction solvents, but also extracts obtained through ordinary purification and fermentation processes. For example, decompression by carbon dioxide, extraction by supercritical extraction with high temperature, extraction by extraction using ultrasound, separation by ultrafiltration membrane with constant molecular weight cutoff value, various chromatography (size, charge, hydrophobic or affinity And the active fraction obtained through various purification and extraction methods, such as an extract obtained by fermentation products using natural or various microorganisms, are also included in the extract of the present invention.

Further, the present invention provides a cosmetic composition characterized in that the above extract is obtained by liquid-freezing obtained by cold-pressing and heating filtration at room temperature, and further by concentrating or lyophilizing the solvent under reduced pressure.

The supercritical fluid extraction refers to supercritical fluid extraction. Generally, the supercritical fluid is extracted from the liquid and the liquid when the gas reaches the critical point at high temperature and high pressure. Gas properties and chemically similar polarity to nonpolar solvents. Due to these properties, supercritical fluids have been used to extract lipophilic materials

Carbon dioxide is a supercritical fluid with both liquid and gaseous nature, with the operation of supercritical fluid equipment reaching its critical pressure and temperature, resulting in increased solubility in fat-soluble solutes. When supercritical carbon dioxide passes through an extraction vessel containing a certain amount of sample, the lipophilic substance contained in the sample is extracted into supercritical carbon dioxide.

When the supernatant carbon dioxide containing a small amount of cosolvent is passed through the sample remaining in the extraction vessel after extracting the lipid-soluble substance, components that were not extracted by pure supercritical carbon dioxide can be extracted.

The supercritical fluid used in the supercritical extraction method of the present invention can effectively extract an active ingredient by using a mixed fluid in which a cosolvent is further mixed with supercritical carbon dioxide or carbon dioxide.

These co-solvents may be used alone or in admixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, hexane and diethyl ether.

Most of the extracted samples contain carbon dioxide. Since the carbon dioxide is volatilized into air at room temperature, the extract obtained by the above method can be used as a cosmetic composition, and the cosolvent can be removed by a reduced pressure evaporator.

In addition, the ultrasonic extraction method is an extraction method using energy generated by ultrasonic vibration. Ultrasonic waves can destroy an insoluble solvent contained in a sample in a water-soluble solvent. Due to the high local temperature, Since the kinetic energy of the reactant particles is increased, sufficient energy required for the reaction is obtained. By inducing the high pressure by the shock effect of the ultrasonic energy, the mixing effect of the substance contained in the sample and the solvent is enhanced, thereby increasing the extraction efficiency.

As the extraction solvent which can be used for the ultrasonic extraction method, one or a mixture of two or more selected from the group consisting of chloroform, ethanol, methanol, water, ethyl acetate, hexane and diethyl ether can be used. The extracted sample is recovered by vacuum filtration, and the filtrate is recovered, and the extract is removed by a vacuum evaporator and freeze-dried to obtain an extract.

According to the present invention, the Tiger nuts extract is contained in an amount of 0.0001 to 30.0% by weight based on the total weight of the cosmetic composition, more preferably the Tiger nut extract is contained in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic composition . When the content of the extract is less than 0.0001% by weight, the skin moisturizing effect is not exhibited. When the content is more than 30.0% by weight, the skin moisturizing effect is insignificantly increased with respect to the increase of the content. It is not even.

Accordingly, the cosmetic composition of the present invention containing the Tiger nut extract having various functions is characterized by having skin moisturizing effect, skin barrier function improving effect and strengthening effect.

The ingredients contained in the cosmetic composition of the present invention may contain, as an active ingredient, the ingredients commonly used in cosmetic compositions in addition to the above-mentioned effective ingredients, and may contain conventional ingredients such as antioxidants, stabilizers, solubilizers, vitamins, Supplements, and carriers.

The cosmetic composition of the present invention can be prepared into any of the formulations conventionally produced in the art and can be used in the form of solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, , Oil, powdered foundation, emulsion foundation, wax foundation, pack, massage cream and spray, but is not limited thereto. More specifically, it can be manufactured in the form of a soft lotion, a nutritional lotion, a nutritional cream, a massage cream, an essence, an eye cream, a cleansing cream, a cleansing foam, a cleansing water, a pack, a spray or a powder.

When the formulation of the present invention is a paste, cream or gel, an animal oil, vegetable oil, wax, paraffin, starch, tracant, cellulose derivative, polyethylene glycol, silicone, bentonite, silica, talc or zinc oxide may be used as the carrier component .

When the formulation of the present invention is a solution or an emulsion, a solvent, a dissolving agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, , 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid esters.

In the case where the formulation of the present invention is a suspension, a carrier such as water, a liquid diluent such as ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester and polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar or tracant, etc. may be used.

When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, / Propane or dimethyl ether.

When the formulation of the present invention is a surfactant-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide ether Alkylamido betaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, or ethoxylated glycerol fatty acid ester.

When the cosmetic composition of the present invention is a soap, a surfactant-containing cleansing formulation or a surfactant-free cleansing formulation, it may be applied to the skin and then wiped off, washed or rinsed with water. The surfactant-containing cleansing formulation may be a cleansing foam, a cleansing water, a cleansing towel and a cleansing pack. The surfactant-free cleansing formulation may be a cleansing cream, , Cleansing lotion, cleansing water and cleansing gel, but is not limited thereto.

On the other hand, the cosmetic process of the present invention refers to all cosmetic processes using the cosmetic composition of the present invention. That is, all methods known in the art using a cosmetic composition belong to the cosmetic method of the present invention.

The cosmetic composition of the present invention may be used alone or in combination, or may be used in combination with other cosmetic compositions other than the present invention. The cosmetic composition according to the present invention may be used according to a conventional method of use, and may be used in a number of times depending on the skin condition or taste of the user.

By carrying out the cosmetic method using the cosmetic composition comprising the Tiger nuts extract of the present invention, skin moisturizing effect, skin barrier function improvement and strengthening effect can be obtained.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these embodiments are only for describing the present invention in more detail and that the scope of the present invention is not limited by these embodiments in accordance with the gist of the present invention .

Manufacturing example  One: Tiger nuts  Extract preparation

1 kg of shredded Tiger nuts was refluxed for 3 hours with 70% (v / v) aqueous ethanol solution for 5 hours, followed by cooling and filtering through Whatman # 4 filter paper. The filtered extract was concentrated under reduced pressure at 50 DEG C or below and lyophilized to obtain 45 g.

Manufacturing example  2 and 3: Supercritical  Manufacture of fluid extracts and ultrasonic extracts

One kilogram of shredded tiger nuts were extracted with conventional supercritical extraction (extraction with ethanol as a co-solvent under a supercritical condition at a temperature of about 60 DEG C and a pressure of about 300 atm) to give a supercritical extract Example 2). Further, 1 kg of finely shaded tiger nuts was extracted with ultrasonic waves (at a temperature of 30 캜 for about 2 hours at a strength of 25 KHz using a super sonic ultrasonic device) to obtain an ultrasonic extract (Production Example 3). In the case of Production Example 3, ethanol was used as a co-solvent.

Comparative Manufacturing Example  One: Tiger nuts  Manufacture of oil

1 kg of Tiger nuts was washed and dried, put on a compactor (Dongkwang Oil.Co., Seoul, Korea), pressed with a force of 600 kg / cm ² for 2 minutes, and the flowing oil was recovered.

Formulation Example  One: Tiger nuts  Extract-containing Cosmetics  Preparation of composition

Cosmetic preparations containing the Tiger nuts extract were prepared in the same manner as the cosmetic preparations containing the Tiger nuts extracts of Preparation Examples 1 to 3 (Formulation Examples 1, 2 and 3). For comparison of the efficacy, glycerin and 1 , Cosmetic composition (Comparative Formulation Example 2) containing a cosmetic composition containing 3-butylene glycol (Comparative Formulation Example 1), Tiger nuts oil (Comparative Preparation Example 1), cosmetic composition containing no extract or moisturizer Formulation Example 3) is shown in Table 1 below.

division ingredient Formulation Example 1 Formulation Example 2 Formulation Example 3 compare
Formulation Example 1 compare
Formulation Example 2 compare
Formulation Example 3 A Tiger nuts extract
(Production Example 1) 5.0 - - - - Tiger nuts extract
(Production Example 2) - 5.0 - - - Tiger nuts extract
(Production Example 3) - - 5.0 -  -  - Tiger nuts oil
(Comparative Production Example 1) - - - - 5.0 - glycerin - - - 5.0 - - 1,3-butylene glycol - - - 5.0 - - EDTA-2Na 0.02 0.02 0.02 0.02 0.02 0.02 Purified water to 100 to 100 to 100 to 100 to 100 to 100 B Cetostearyl alcohol 2.0 2.0 2.0 2.0 2.0 2.0 Glyceryl stearate 1.5 1.5 1.5 1.5 1.5 1.5 Microcrystalline 0.7 0.7 0.7 0.7 0.7 0.7 Squalane 5.0 5.0 5.0 5.0 5.0 5.0 Liquid paraffin 3.0 3.0 3.0 3.0 3.0 3.0 Trioctanoin 5.0 5.0 5.0 5.0 5.0 5.0 Polysorbate 1.2 1.2 1.2 1.2 1.2 1.2 Sorbitan stearate 0.5 0.5 0.5 0.5 0.5 0.5 Tocopheryl acetate 0.2 0.2 0.2 0.2 0.2 0.2 Cyclomethicone 3.0 3.0 3.0 3.0 3.0 3.0 BHT 0.05 0.05 0.05 0.05 0.05 0.05 C Incense, preservative Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount Suitable amount

Experimental Example  1. Skin barrier strengthening effect TEWL )

TEWL (Trans-Epidermal Water Loss) is an index of moisture (excluding sweat) that evaporates through the skin and is used to assess the extent of damage to the stratum corneum and skin barrier function. A high level of TEWL indicates that the skin barrier is damaged. TEWL was measured at constant temperature (22 ° C) and humidity (47%), and the unit was g / h / m ² . The method of measurement was as follows: First, 30 times of tape-stripping was performed to cause damage to the skin barrier. TEWL values prior to skin barrier damage, TEWL values before application of the test product after inducing skin barrier damage, and TEWL values after 3 days of product application were measured using a Tewameter TM210 (Courage + Khazaka, Germany) And the recovery of transdermal water loss was calculated.

Name of sample TEWL value TEWL Recovery (%) Stripping After stripping Three days after application Formulation Example 1 6.5 18.2 8.3 84.6 Formulation Example 2 6.8 18.6 8.4 86.4 Formulation Example 3 6.9 18.5 7.7 93.1 Comparative Formulation Example 1 7 18.4 10.9 65.7 Comparative Formulation Example 2 7.2 18.6 12.1 57.0 Comparative Formulation Example 3 6.5 18.7 12.3 52.4

Table 2 shows that Formulation Examples 1 to 3 containing Tiger nuts extract had higher recovery than Comparative Formulations 1 to 3. In particular, Formulation Example 3 showed the most excellent effect.

Experimental Example  2: Tiger nuts  Moisturizing effect of extract

The clinical moisturizing effects of the cosmetic compositions of Formulation Examples 1, 2 and 3 were measured as follows. A, B and C groups were divided into 6 groups (A, B, C, D, E, F) by randomly dividing 150 healthy men and women who felt skin dry through a questionnaire. A cosmetic composition (Comparative Formulation Example 1) containing glycerin and 1,3-butylene glycol as a moisturizing agent instead of the Tiger nuts extract as the D group, and a cosmetic composition containing Tiger nuts oil as the E group (Comparative Formulation Example 2), and a cosmetic composition (Comparative Formulation Example 3) containing no Tiger nuts extract and a moisturizer were applied to the face group for 2 weeks twice a day, respectively. The moisturizing effect was evaluated by the Corneometer CM 820 (Corage + Khazaka, Germany) after every week and after the end of the test. The experimental results are shown in Table 3 below.

division Before use After 2 weeks of use After 4 weeks of use Formulation Example 1 20.5 34.3 44.2 Formulation Example 2 22.6 36.6 47.9 Formulation Example 3 22.5 38.0 48.6 Comparative Formulation Example 1 22.2 25.5 30.9 Comparative Formulation Example 2 22.8 29.1 33.6 Comparative Formulation Example 3 21.1 23.4 26.3

As shown in Table 3 above, the cosmetic composition containing Comparative Example 1 and the cosmetic containing Tiger nuts oil (Comparative Formulation Example 2) containing the other moisturizing agents of the present invention (Comparative Formulation Example 2) The moisturizing effect of Examples 1, 2 and 3 was excellent.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the same is by way of illustration and example only and is not to be construed as limiting the scope of the present invention. It is therefore intended that the scope of the invention be defined by the claims appended hereto and their equivalents.

Claims (4)

A cosmetic composition for moisturizing the skin, comprising as an active ingredient an extract of Tiger nuts ( Cyperus esculentus L. ) extracted by supercritical extraction or ultrasonic extraction. The cosmetic composition for skin moisturizing according to claim 1, wherein the cosmetic composition has a skin barrier function and a skin barrier function. The cosmetic composition for skin moisturizing according to claim 1, wherein the extract of Tiger nuts ( Cyperus esculentus L. ) is contained in an amount of 0.0001 to 30.0% by weight based on the total weight of the cosmetic composition. delete