KR20180121571A - Liv1-adc와 화학요법제를 사용한 병용 요법 - Google Patents

Liv1-adc와 화학요법제를 사용한 병용 요법 Download PDF

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KR20180121571A
KR20180121571A KR1020187028273A KR20187028273A KR20180121571A KR 20180121571 A KR20180121571 A KR 20180121571A KR 1020187028273 A KR1020187028273 A KR 1020187028273A KR 20187028273 A KR20187028273 A KR 20187028273A KR 20180121571 A KR20180121571 A KR 20180121571A
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liv
adc
cancer
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administered
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Korean (ko)
Inventor
장고 수스만
푸 리
아나 코스틱
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시애틀 지네틱스, 인크.
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Priority to KR1020227039721A priority Critical patent/KR20220157515A/ko
Publication of KR20180121571A publication Critical patent/KR20180121571A/ko
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    • A61K47/6855Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015Breast
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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KR1020187028273A 2016-03-15 2017-03-15 Liv1-adc와 화학요법제를 사용한 병용 요법 Ceased KR20180121571A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227039721A KR20220157515A (ko) 2016-03-15 2017-03-15 Liv1-adc와 화학요법제를 사용한 병용 요법

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662308639P 2016-03-15 2016-03-15
US62/308,639 2016-03-15
US201662317792P 2016-04-04 2016-04-04
US62/317,792 2016-04-04
US201662367510P 2016-07-27 2016-07-27
US62/367,510 2016-07-27
PCT/US2017/022541 WO2017161007A1 (en) 2016-03-15 2017-03-15 Combination therapy using a liv1-adc and a chemotherapeutic

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020227039721A Division KR20220157515A (ko) 2016-03-15 2017-03-15 Liv1-adc와 화학요법제를 사용한 병용 요법

Publications (1)

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KR20180121571A true KR20180121571A (ko) 2018-11-07

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Application Number Title Priority Date Filing Date
KR1020187028273A Ceased KR20180121571A (ko) 2016-03-15 2017-03-15 Liv1-adc와 화학요법제를 사용한 병용 요법
KR1020237041743A Withdrawn KR20230169462A (ko) 2016-03-15 2017-03-15 Liv1-adc와 체크포인트 억제제를 사용한 병용 요법
KR1020227039721A Ceased KR20220157515A (ko) 2016-03-15 2017-03-15 Liv1-adc와 화학요법제를 사용한 병용 요법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020237041743A Withdrawn KR20230169462A (ko) 2016-03-15 2017-03-15 Liv1-adc와 체크포인트 억제제를 사용한 병용 요법
KR1020227039721A Ceased KR20220157515A (ko) 2016-03-15 2017-03-15 Liv1-adc와 화학요법제를 사용한 병용 요법

Country Status (14)

Country Link
US (2) US11325980B2 (https=)
EP (1) EP3429626A4 (https=)
JP (3) JP2019508433A (https=)
KR (3) KR20180121571A (https=)
CN (1) CN108697801A (https=)
AU (2) AU2017235545A1 (https=)
BR (1) BR112018068129A2 (https=)
CA (1) CA3016485A1 (https=)
EA (1) EA201891968A1 (https=)
IL (1) IL261505A (https=)
MA (1) MA45324A (https=)
MX (2) MX2018010847A (https=)
SG (2) SG11201807526SA (https=)
WO (1) WO2017161007A1 (https=)

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EP2648752B1 (en) 2010-12-06 2017-02-15 Seattle Genetics, Inc. Humanized antibodies to liv-1 and use of same to treat cancer
SG11202004751TA (en) * 2017-12-01 2020-06-29 Seattle Genetics Inc Humanized anti-liv1 antibodies for the treatment of breast cancer
WO2020095249A1 (en) 2018-11-07 2020-05-14 Crispr Therapeutics Ag Anti-liv1 immune cell cancer therapy
KR20220114002A (ko) * 2019-12-09 2022-08-17 씨젠 인크. Liv1-adc 및 pd-1 길항제를 사용하는 병용 요법
TW202229346A (zh) * 2020-09-28 2022-08-01 美商西根公司 用於治療癌症之人化抗liv1抗體
BR112023018676A2 (pt) 2021-03-18 2023-10-10 Seagen Inc Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco
AU2024235054A1 (en) * 2023-03-15 2025-10-02 BioRay Pharmaceutical Co., Ltd. Anti-liv-1 antibody and anti-liv-1 antibody-drug conjugate, and pharmaceutical use thereof
WO2025162207A1 (zh) * 2024-01-31 2025-08-07 上海复宏汉霖生物技术股份有限公司 抗liv1抗体及使用方法
WO2026057076A1 (zh) * 2024-09-14 2026-03-19 杭州博之锐生物制药有限公司 基于抗liv-1抗体-药物偶联物的耐药癌症的治疗

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