AU2017235545A1 - Combination therapy using a LIV1-ADC and a chemotherapeutic - Google Patents

Combination therapy using a LIV1-ADC and a chemotherapeutic Download PDF

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Publication number
AU2017235545A1
AU2017235545A1 AU2017235545A AU2017235545A AU2017235545A1 AU 2017235545 A1 AU2017235545 A1 AU 2017235545A1 AU 2017235545 A AU2017235545 A AU 2017235545A AU 2017235545 A AU2017235545 A AU 2017235545A AU 2017235545 A1 AU2017235545 A1 AU 2017235545A1
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Australia
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ser
leu
gly
ala
glu
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Abandoned
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AU2017235545A
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English (en)
Inventor
Ana Kostic
Fu LI
Django Sussman
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Seagen Inc
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Seagen Inc
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Publication date
Application filed by Seagen Inc filed Critical Seagen Inc
Publication of AU2017235545A1 publication Critical patent/AU2017235545A1/en
Assigned to SEAGEN INC. reassignment SEAGEN INC. Amend patent request/document other than specification (104) Assignors: SEATTLE GENETICS, INC.
Priority to AU2024201856A priority Critical patent/AU2024201856A1/en
Abandoned legal-status Critical Current

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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
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    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
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    • A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07—ORGANIC CHEMISTRY
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/3015—Breast
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AU2017235545A 2016-03-15 2017-03-15 Combination therapy using a LIV1-ADC and a chemotherapeutic Abandoned AU2017235545A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2024201856A AU2024201856A1 (en) 2016-03-15 2024-03-21 Combination therapy using a LIV1-ADC and a chemotherapeutic

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662308639P 2016-03-15 2016-03-15
US62/308,639 2016-03-15
US201662317792P 2016-04-04 2016-04-04
US62/317,792 2016-04-04
US201662367510P 2016-07-27 2016-07-27
US62/367,510 2016-07-27
PCT/US2017/022541 WO2017161007A1 (en) 2016-03-15 2017-03-15 Combination therapy using a liv1-adc and a chemotherapeutic

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2024201856A Division AU2024201856A1 (en) 2016-03-15 2024-03-21 Combination therapy using a LIV1-ADC and a chemotherapeutic

Publications (1)

Publication Number Publication Date
AU2017235545A1 true AU2017235545A1 (en) 2018-10-25

Family

ID=59852409

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2017235545A Abandoned AU2017235545A1 (en) 2016-03-15 2017-03-15 Combination therapy using a LIV1-ADC and a chemotherapeutic
AU2024201856A Abandoned AU2024201856A1 (en) 2016-03-15 2024-03-21 Combination therapy using a LIV1-ADC and a chemotherapeutic

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2024201856A Abandoned AU2024201856A1 (en) 2016-03-15 2024-03-21 Combination therapy using a LIV1-ADC and a chemotherapeutic

Country Status (14)

Country Link
US (2) US11325980B2 (https=)
EP (1) EP3429626A4 (https=)
JP (3) JP2019508433A (https=)
KR (3) KR20180121571A (https=)
CN (1) CN108697801A (https=)
AU (2) AU2017235545A1 (https=)
BR (1) BR112018068129A2 (https=)
CA (1) CA3016485A1 (https=)
EA (1) EA201891968A1 (https=)
IL (1) IL261505A (https=)
MA (1) MA45324A (https=)
MX (2) MX2018010847A (https=)
SG (2) SG11201807526SA (https=)
WO (1) WO2017161007A1 (https=)

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SG11202004751TA (en) * 2017-12-01 2020-06-29 Seattle Genetics Inc Humanized anti-liv1 antibodies for the treatment of breast cancer
WO2020095249A1 (en) 2018-11-07 2020-05-14 Crispr Therapeutics Ag Anti-liv1 immune cell cancer therapy
KR20220114002A (ko) * 2019-12-09 2022-08-17 씨젠 인크. Liv1-adc 및 pd-1 길항제를 사용하는 병용 요법
TW202229346A (zh) * 2020-09-28 2022-08-01 美商西根公司 用於治療癌症之人化抗ｌｉｖ１抗體
BR112023018676A2 (pt) 2021-03-18 2023-10-10 Seagen Inc Conjugado anticorpo-fármaco, composição farmacêutica, métodos de tratamento de uma doença ou condição e de um câncer, e, composição de conjugado ligante-fármaco
AU2024235054A1 (en) * 2023-03-15 2025-10-02 BioRay Pharmaceutical Co., Ltd. Anti-liv-1 antibody and anti-liv-1 antibody-drug conjugate, and pharmaceutical use thereof
WO2025162207A1 (zh) * 2024-01-31 2025-08-07 上海复宏汉霖生物技术股份有限公司 抗liv1抗体及使用方法
WO2026057076A1 (zh) * 2024-09-14 2026-03-19 杭州博之锐生物制药有限公司 基于抗liv-1抗体-药物偶联物的耐药癌症的治疗

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