JP2019508433A - Liv1−adc及び化学療法剤を用いた併用療法 - Google Patents

Liv1−adc及び化学療法剤を用いた併用療法 Download PDF

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JP2019508433A
JP2019508433A JP2018546036A JP2018546036A JP2019508433A JP 2019508433 A JP2019508433 A JP 2019508433A JP 2018546036 A JP2018546036 A JP 2018546036A JP 2018546036 A JP2018546036 A JP 2018546036A JP 2019508433 A JP2019508433 A JP 2019508433A
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liv
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administered
adc
cancer
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サスマン,ジアンゴ
リー,フー
コスティチ,アナ
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シアトル ジェネティクス,インコーポレーテッド
シアトル ジェネティクス,インコーポレーテッド
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Publication of JP2019508433A5 publication Critical patent/JP2019508433A5/ja
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Priority to JP2024039750A priority patent/JP2024075639A/ja
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    • A61K47/6855Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
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    • A61K9/0012Galenical forms characterised by the site of application
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    • C07KPEPTIDES
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    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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JP2018546036A 2016-03-15 2017-03-15 Liv1−adc及び化学療法剤を用いた併用療法 Pending JP2019508433A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022006944A JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法
JP2024039750A JP2024075639A (ja) 2016-03-15 2024-03-14 Liv1-adc及び化学療法剤を用いた併用療法

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662308639P 2016-03-15 2016-03-15
US62/308,639 2016-03-15
US201662317792P 2016-04-04 2016-04-04
US62/317,792 2016-04-04
US201662367510P 2016-07-27 2016-07-27
US62/367,510 2016-07-27
PCT/US2017/022541 WO2017161007A1 (en) 2016-03-15 2017-03-15 Combination therapy using a liv1-adc and a chemotherapeutic

Related Child Applications (1)

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JP2022006944A Division JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法

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JP2019508433A true JP2019508433A (ja) 2019-03-28
JP2019508433A5 JP2019508433A5 (https=) 2020-04-23

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JP2018546036A Pending JP2019508433A (ja) 2016-03-15 2017-03-15 Liv1−adc及び化学療法剤を用いた併用療法
JP2022006944A Pending JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法
JP2024039750A Pending JP2024075639A (ja) 2016-03-15 2024-03-14 Liv1-adc及び化学療法剤を用いた併用療法

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JP2022006944A Pending JP2022058676A (ja) 2016-03-15 2022-01-20 Liv1-adc及び化学療法剤を用いた併用療法
JP2024039750A Pending JP2024075639A (ja) 2016-03-15 2024-03-14 Liv1-adc及び化学療法剤を用いた併用療法

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US (2) US11325980B2 (https=)
EP (1) EP3429626A4 (https=)
JP (3) JP2019508433A (https=)
KR (3) KR20180121571A (https=)
CN (1) CN108697801A (https=)
AU (2) AU2017235545A1 (https=)
BR (1) BR112018068129A2 (https=)
CA (1) CA3016485A1 (https=)
EA (1) EA201891968A1 (https=)
IL (1) IL261505A (https=)
MA (1) MA45324A (https=)
MX (2) MX2018010847A (https=)
SG (2) SG10201912908QA (https=)
WO (1) WO2017161007A1 (https=)

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Publication number Priority date Publication date Assignee Title
JP6105481B2 (ja) 2010-12-06 2017-03-29 シアトル ジェネティクス,インコーポレーテッド Liv−1に対するヒト化抗体および癌治療のためのその使用
MA50943A (fr) * 2017-12-01 2020-10-07 Seattle Genetics Inc Anticorps anti-liv1 humanisés pour le traitement du cancer du sein
CN113015750A (zh) 2018-11-07 2021-06-22 克里斯珀医疗股份公司 抗liv1免疫细胞癌症疗法
BR112022011268A2 (pt) * 2019-12-09 2022-09-06 Seagen Inc Terapia de combinação com antagonista de liv1-adc e pd1
MX2023003404A (es) * 2020-09-28 2023-03-31 Seagen Inc Anticuerpos anti-l1vi humanizados para el tratamiento del cancer.
AU2022238571A1 (en) 2021-03-18 2023-09-14 Seagen Inc. Selective drug release from internalized conjugates of biologically active compounds
JP2026509871A (ja) * 2023-03-15 2026-03-25 浙江博鋭生物製薬有限公司 抗liv-1抗体及び抗liv-1抗体薬物複合体並びにその薬物的使用
WO2025162207A1 (zh) * 2024-01-31 2025-08-07 上海复宏汉霖生物技术股份有限公司 抗liv1抗体及使用方法
WO2026057076A1 (zh) * 2024-09-14 2026-03-19 杭州博之锐生物制药有限公司 基于抗liv-1抗体-药物偶联物的耐药癌症的治疗

Citations (3)

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JP2014506120A (ja) * 2010-12-06 2014-03-13 シアトル ジェネティクス,インコーポレーテッド Liv−1に対するヒト化抗体および癌治療のためのその使用
WO2015002134A1 (ja) * 2013-07-02 2015-01-08 公益財団法人がん研究会 細胞性免疫誘導ワクチン
WO2015155976A1 (ja) * 2014-04-10 2015-10-15 第一三共株式会社 抗her2抗体-薬物コンジュゲート

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