KR20180054713A - 조율가능한 변종 면역글로불린 수퍼패밀리 도메인 및 유전자 조작된 세포 치료법 - Google Patents
조율가능한 변종 면역글로불린 수퍼패밀리 도메인 및 유전자 조작된 세포 치료법 Download PDFInfo
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- KR20180054713A KR20180054713A KR1020187010556A KR20187010556A KR20180054713A KR 20180054713 A KR20180054713 A KR 20180054713A KR 1020187010556 A KR1020187010556 A KR 1020187010556A KR 20187010556 A KR20187010556 A KR 20187010556A KR 20180054713 A KR20180054713 A KR 20180054713A
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562218531P | 2015-09-14 | 2015-09-14 | |
| US62/218,531 | 2015-09-14 | ||
| US201662323608P | 2016-04-15 | 2016-04-15 | |
| US201662323595P | 2016-04-15 | 2016-04-15 | |
| US62/323,595 | 2016-04-15 | ||
| US62/323,608 | 2016-04-15 | ||
| US201662367822P | 2016-07-28 | 2016-07-28 | |
| US201662367819P | 2016-07-28 | 2016-07-28 | |
| US62/367,822 | 2016-07-28 | ||
| US62/367,819 | 2016-07-28 | ||
| PCT/US2016/051786 WO2017048878A1 (en) | 2015-09-14 | 2016-09-14 | Tunable variant immunoglobulin superfamily domains and engineered cell therapy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20180054713A true KR20180054713A (ko) | 2018-05-24 |
Family
ID=57068203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187010556A Withdrawn KR20180054713A (ko) | 2015-09-14 | 2016-09-14 | 조율가능한 변종 면역글로불린 수퍼패밀리 도메인 및 유전자 조작된 세포 치료법 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20180256644A1 (https=) |
| EP (1) | EP3350206A1 (https=) |
| JP (1) | JP2018534245A (https=) |
| KR (1) | KR20180054713A (https=) |
| CN (1) | CN108513576A (https=) |
| AU (1) | AU2016323069A1 (https=) |
| BR (1) | BR112018004965A2 (https=) |
| CA (1) | CA2997217A1 (https=) |
| EA (1) | EA201890729A1 (https=) |
| IL (1) | IL258102A (https=) |
| MX (1) | MX2018003144A (https=) |
| WO (1) | WO2017048878A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20150131208A (ko) | 2013-03-13 | 2015-11-24 | 이미지냅 인코포레이티드 | Cd8에의 항원 결합 구조체들 |
| CN121159719A (zh) | 2015-04-17 | 2025-12-19 | 高山免疫科学股份有限公司 | 具有可调的亲和力的免疫调节蛋白 |
| US11254744B2 (en) | 2015-08-07 | 2022-02-22 | Imaginab, Inc. | Antigen binding constructs to target molecules |
| US10273281B2 (en) | 2015-11-02 | 2019-04-30 | Five Prime Therapeutics, Inc. | CD80 extracellular domain polypeptides and their use in cancer treatment |
| WO2017181152A2 (en) | 2016-04-15 | 2017-10-19 | Alpine Immune Sciences, Inc. | Cd80 variant immunomodulatory proteins and uses thereof |
| MX2018012472A (es) | 2016-04-15 | 2019-08-12 | Alpine Immune Sciences Inc | Proteinas inmunomoduladoras variantes de ligando icos y sus usos. |
| US11471488B2 (en) | 2016-07-28 | 2022-10-18 | Alpine Immune Sciences, Inc. | CD155 variant immunomodulatory proteins and uses thereof |
| WO2018022945A1 (en) | 2016-07-28 | 2018-02-01 | Alpine Immune Sciences, Inc. | Cd112 variant immunomodulatory proteins and uses thereof |
| WO2018075978A1 (en) * | 2016-10-20 | 2018-04-26 | Alpine Immune Sciences, Inc. | Secretable variant immunomodulatory proteins and engineered cell therapy |
| KR20190141146A (ko) | 2017-03-16 | 2019-12-23 | 알파인 이뮨 사이언시즈, 인코포레이티드 | Pd-l2 변이체 면역조절 단백질 및 그의 용도 |
| SG11201907769XA (en) | 2017-03-16 | 2019-09-27 | Alpine Immune Sciences Inc | Cd80 variant immunomodulatory proteins and uses thereof |
| KR20190139216A (ko) | 2017-04-28 | 2019-12-17 | 파이브 프라임 테라퓨틱스, 인크. | Cd80 세포외 도메인 폴리펩티드를 이용한 치료 방법 |
| US11306144B2 (en) | 2017-08-25 | 2022-04-19 | Five Prime Therapeutics, Inc. | B7-H4 antibodies and methods of use thereof |
| JP7749319B2 (ja) | 2017-10-10 | 2025-10-06 | アルパイン イミューン サイエンシズ インコーポレイテッド | Ctla-4変異型免疫調節タンパク質およびそれらの使用 |
| BR112020007542A2 (pt) * | 2017-10-18 | 2020-12-01 | Alpine Immune Sciences, Inc. | proteínas imunomoduladoras ligantes de icos variantes e composições e métodos relacionados |
| AU2019205273B2 (en) * | 2018-01-03 | 2024-04-04 | Alpine Immune Sciences, Inc. | Multi-domain immunomodulatory proteins and methods of use thereof |
| BR112020016986A2 (pt) | 2018-02-21 | 2021-03-02 | Five Prime Therapeutics, Inc. | formulações de anticorpo contra b7-h4 |
| KR20200144094A (ko) | 2018-03-02 | 2020-12-28 | 파이브 프라임 테라퓨틱스, 인크. | B7-h4 항체 및 이의 사용 방법 |
| WO2019241758A1 (en) | 2018-06-15 | 2019-12-19 | Alpine Immune Sciences, Inc. | Pd-1 variant immunomodulatory proteins and uses thereof |
| JP2021534196A (ja) | 2018-08-23 | 2021-12-09 | シージェン インコーポレイテッド | 抗tigit抗体 |
| CA3120868A1 (en) | 2018-11-30 | 2020-06-04 | Alpine Immune Sciences, Inc. | Cd86 variant immunomodulatory proteins and uses thereof |
| CA3124721A1 (en) * | 2018-12-24 | 2020-07-02 | Xiaoyi Zhou | Recombinant human 21g-b7-h3 protein coding gene, recombinant vector, host cell comprising the same, pharmaceutical composition and use thereof |
| EP3908372A1 (en) * | 2019-01-13 | 2021-11-17 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Antibodies specific to human nectin-2 |
| US12589132B2 (en) | 2019-02-22 | 2026-03-31 | Five Prime Therapeutics, Inc. | CD80 extracellular domain Fc fusion proteins for treating PD-L1 negative tumors |
| JP7535273B2 (ja) * | 2019-04-26 | 2024-08-16 | スアンズ バイオファーマシューティカル カンパニー,リミテッド | Cd80バリアントタンパク質とその使用 |
| WO2020243134A1 (en) | 2019-05-27 | 2020-12-03 | Immatics US, Inc. | Viral vectors and their use in adoptive cellular therapy |
| WO2021050789A1 (en) | 2019-09-10 | 2021-03-18 | Obsidian Therapeutics, Inc. | Ca2-il15 fusion proteins for tunable regulation |
| CN110859951A (zh) * | 2019-09-23 | 2020-03-06 | 中国药科大学 | Cd200蛋白和cd200融合蛋白在制备治疗银屑病药物中的应用 |
| CN113087806B (zh) * | 2019-12-31 | 2022-09-06 | 华东师范大学 | 靶向多种肿瘤的新型car-t细胞及其制备和方法 |
| EP4146684A2 (en) | 2020-05-08 | 2023-03-15 | Alpine Immune Sciences, Inc. | April and baff inhibitory immunomodulatory proteins with and without a t cell inhibitory protein and methods of use thereof |
| WO2022170033A1 (en) * | 2021-02-04 | 2022-08-11 | The Trustees Of Dartmouth College | Engineered natural ligand-based car: directed evolution of the stress-receptor nkp30 |
| KR20240152879A (ko) | 2022-02-28 | 2024-10-22 | 넥틴 테라퓨틱스 리미티드 | 넥틴-2에 대한 인간화 항체 및 이의 약물 접합체 |
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| US5773253A (en) * | 1993-01-22 | 1998-06-30 | Bristol-Myers Squibb Company | MYPPPY variants of CTL A4 and uses thereof |
| US7183376B2 (en) * | 2000-06-23 | 2007-02-27 | Maxygen, Inc. | Variant B7 co-stimulatory molecules |
| EP1360290A2 (en) * | 2000-06-23 | 2003-11-12 | Maxygen, Inc. | Co-stimulatory molecules |
| SI2856876T1 (en) * | 2007-03-30 | 2018-04-30 | Memorial Sloan-Kettering Cancer Center | Constitutive expression of costimulatory ligands on adoptively transferred T lymphocytes |
| CN103796681B (zh) * | 2011-06-30 | 2018-07-20 | 建新公司 | T细胞活化的抑制剂 |
| US8956619B2 (en) * | 2011-10-25 | 2015-02-17 | University Of Maryland, Baltimore County | Soluble CD80 as a therapeutic to reverse immune supression in cancer patients |
| WO2013169338A1 (en) * | 2012-05-11 | 2013-11-14 | Medimmune, Llc | Ctla-4 variants |
| GB201311475D0 (en) * | 2013-06-27 | 2013-08-14 | Alligator Bioscience Ab | Polypeptides |
| CN121159719A (zh) * | 2015-04-17 | 2025-12-19 | 高山免疫科学股份有限公司 | 具有可调的亲和力的免疫调节蛋白 |
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- 2016-09-14 KR KR1020187010556A patent/KR20180054713A/ko not_active Withdrawn
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| WO2017048878A1 (en) | 2017-03-23 |
| US20180256644A1 (en) | 2018-09-13 |
| MX2018003144A (es) | 2018-09-11 |
| AU2016323069A1 (en) | 2018-04-12 |
| EP3350206A1 (en) | 2018-07-25 |
| BR112018004965A2 (pt) | 2018-10-09 |
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