KR20180039622A - 경피 흡수 조성물 - Google Patents

경피 흡수 조성물 Download PDF

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Publication number
KR20180039622A
KR20180039622A KR1020187001366A KR20187001366A KR20180039622A KR 20180039622 A KR20180039622 A KR 20180039622A KR 1020187001366 A KR1020187001366 A KR 1020187001366A KR 20187001366 A KR20187001366 A KR 20187001366A KR 20180039622 A KR20180039622 A KR 20180039622A
Authority
KR
South Korea
Prior art keywords
sorbic acid
composition
transdermal absorption
basic drug
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020187001366A
Other languages
English (en)
Korean (ko)
Inventor
야스시 미와
히데토시 하마모토
나오야 아카자와
Original Assignee
가부시키가이샤 메드렉스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 가부시키가이샤 메드렉스 filed Critical 가부시키가이샤 메드렉스
Publication of KR20180039622A publication Critical patent/KR20180039622A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
KR1020187001366A 2015-08-29 2016-08-29 경피 흡수 조성물 Withdrawn KR20180039622A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPPCT/JP2015/074553 2015-08-29
PCT/JP2015/074553 WO2017037813A1 (ja) 2015-08-29 2015-08-29 塩基性薬物とソルビン酸とを含有する経皮吸収組成物
PCT/JP2016/075203 WO2017038767A1 (ja) 2015-08-29 2016-08-29 経皮吸収組成物

Publications (1)

Publication Number Publication Date
KR20180039622A true KR20180039622A (ko) 2018-04-18

Family

ID=58187853

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020187001366A Withdrawn KR20180039622A (ko) 2015-08-29 2016-08-29 경피 흡수 조성물

Country Status (16)

Country Link
US (3) US9974858B2 (cg-RX-API-DMAC10.html)
EP (1) EP3342423B1 (cg-RX-API-DMAC10.html)
JP (2) JP6259117B2 (cg-RX-API-DMAC10.html)
KR (1) KR20180039622A (cg-RX-API-DMAC10.html)
CN (1) CN107427509B (cg-RX-API-DMAC10.html)
BR (1) BR112018001387B8 (cg-RX-API-DMAC10.html)
CO (1) CO2018001831A2 (cg-RX-API-DMAC10.html)
ES (1) ES2864017T3 (cg-RX-API-DMAC10.html)
MX (1) MX388148B (cg-RX-API-DMAC10.html)
MY (1) MY189987A (cg-RX-API-DMAC10.html)
PH (1) PH12018500271A1 (cg-RX-API-DMAC10.html)
RU (1) RU2702356C2 (cg-RX-API-DMAC10.html)
SG (1) SG11201800043UA (cg-RX-API-DMAC10.html)
UA (1) UA123212C2 (cg-RX-API-DMAC10.html)
WO (2) WO2017037813A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201800296B (cg-RX-API-DMAC10.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107427509B (zh) 2015-08-29 2021-06-15 美德阿利克斯株式会社 含有碱性药物和山梨酸的经皮吸收组成物
US11559519B2 (en) 2018-01-31 2023-01-24 Medrx, Co., Ltd. Tizanidine therapy system
US11186585B2 (en) 2018-08-17 2021-11-30 Kappa-Pharma LLC Compositions and methods of enhancing opioid receptor engagement by opioid hexadienoates and optionally substituted hexadienoates
TWI772807B (zh) * 2019-05-27 2022-08-01 日商救急藥品工業股份有限公司 外用製劑
CA3149152A1 (en) * 2019-08-11 2021-02-18 Kappa-Pharma LLC Compositions and methods of enhancing opioid receptor engagement by opioid hexadienoates and optionally substituted hexadienoates
CA3168199A1 (en) 2020-02-19 2021-08-26 Eri ICHIBAYASHI Transdermal absorption preparation
US12103639B2 (en) * 2021-06-03 2024-10-01 Sram, Llc Bicycle control system
US20240374544A1 (en) * 2021-08-30 2024-11-14 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for the transdermal administration of guanfacine comprising guanfacine and a mono-carboxylic acid
CA3232272A1 (en) * 2021-10-15 2023-04-20 Hans-Werner Wolf Transdermal therapeutic system for the transdermal administration of tizanidine
CN116370439A (zh) * 2022-04-01 2023-07-04 江苏山信药业有限公司 一种伐尼克兰透皮贴剂及其制备方法和其应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61172830A (ja) * 1985-01-26 1986-08-04 Showa Denko Kk 皮膚外用剤組成物
CA2378385C (en) * 1999-07-27 2009-01-27 Hisamitsu Pharmaceutical Co., Inc. Patch formulation for external use including an acid addition salt of a basic drug
US20040142024A1 (en) 1999-07-27 2004-07-22 Hisamitsu Pharmaceutical Co., Inc. Patch formulation for external use
DE602005017753D1 (de) * 2004-03-19 2009-12-31 Mcneil Ab Mittel für die transdermale verabreichung von nikotin
JP4807974B2 (ja) * 2005-06-30 2011-11-02 帝國製薬株式会社 経皮吸収促進組成物
CN101032474B (zh) * 2006-03-06 2011-02-16 重庆医药工业研究院有限责任公司 一种治疗或预防神经系统疾病的雷沙吉兰透皮贴片及其制备方法
CN101143127A (zh) * 2007-10-25 2008-03-19 复旦大学 一种酚妥拉明外用制剂及其制备方法
CN103239721B (zh) 2007-11-22 2016-03-16 美德阿利克斯株式会社 包括基于脂肪酸的离子型液体作为活性成分的外用制剂组合物
JP5537412B2 (ja) 2008-02-27 2014-07-02 久光製薬株式会社 貼付製剤
WO2010016219A1 (ja) 2008-08-05 2010-02-11 株式会社メドレックス 塩基性薬効成分の脂肪酸塩、安息香酸塩を含有する外用剤とその製造方法
JP2012158521A (ja) * 2009-04-17 2012-08-23 Kureha Corp 外用剤
EP2476414B1 (en) * 2009-09-07 2015-03-04 NIPRO Patch Co., Ltd. Transdermally absorbable preparation
WO2011157449A1 (en) * 2010-06-18 2011-12-22 Merz Pharma Gmbh & Co. Kgaa Gel formulations for the topical use of 1-amino-alkylcyclohexane derivatives
US10543275B2 (en) * 2012-06-20 2020-01-28 Medrx Co., Ltd. Composition for patch preparation comprising drug, organic solvent, lipophilic mass base, and powder
JP2014125483A (ja) 2012-12-27 2014-07-07 Lion Corp 貼付剤
CN107427509B (zh) * 2015-08-29 2021-06-15 美德阿利克斯株式会社 含有碱性药物和山梨酸的经皮吸收组成物

Also Published As

Publication number Publication date
BR112018001387B1 (pt) 2023-09-05
US20170056502A1 (en) 2017-03-02
CN107427509B (zh) 2021-06-15
JPWO2017038767A1 (ja) 2017-09-07
US10588973B2 (en) 2020-03-17
EP3342423A4 (en) 2018-07-25
ES2864017T3 (es) 2021-10-13
RU2702356C2 (ru) 2019-10-08
UA123212C2 (uk) 2021-03-03
JP2017149782A (ja) 2017-08-31
US9974858B2 (en) 2018-05-22
US11382978B2 (en) 2022-07-12
BR112018001387A2 (pt) 2018-09-11
WO2017037813A1 (ja) 2017-03-09
EP3342423B1 (en) 2021-03-10
RU2018110617A3 (cg-RX-API-DMAC10.html) 2019-09-30
MX2018002015A (es) 2018-06-19
PH12018500271A1 (en) 2018-08-13
CN107427509A (zh) 2017-12-01
RU2018110617A (ru) 2019-09-30
ZA201800296B (en) 2019-04-24
US20200171156A1 (en) 2020-06-04
MX388148B (es) 2025-03-19
JP6259117B2 (ja) 2018-01-10
MY189987A (en) 2022-03-22
BR112018001387B8 (pt) 2024-03-05
US20180236082A1 (en) 2018-08-23
EP3342423A1 (en) 2018-07-04
WO2017038767A1 (ja) 2017-03-09
SG11201800043UA (en) 2018-02-27
CO2018001831A2 (es) 2018-05-21

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Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20180115

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid