KR20170138574A - 항암 융합 폴리펩타이드 - Google Patents

항암 융합 폴리펩타이드 Download PDF

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KR20170138574A
KR20170138574A KR1020177034820A KR20177034820A KR20170138574A KR 20170138574 A KR20170138574 A KR 20170138574A KR 1020177034820 A KR1020177034820 A KR 1020177034820A KR 20177034820 A KR20177034820 A KR 20177034820A KR 20170138574 A KR20170138574 A KR 20170138574A
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glu
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Korean (ko)
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말론 히너
크리스틴 로테
쉐인 올윌
라시다 시함 벨 아이바
울리히 뫼비우스
코리나 슐로서
토마스 진 호아킨
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피어이스 파마슈티컬즈 게엠베하
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Publication of KR20170138574A publication Critical patent/KR20170138574A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020177034820A 2015-05-04 2016-05-04 항암 융합 폴리펩타이드 Pending KR20170138574A (ko)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
EP15166179 2015-05-04
EP15166179.0 2015-05-04
EP15167917 2015-05-18
EP15167917.2 2015-05-18
EP15002702.7 2015-09-17
EP15002702 2015-09-17
EP15192870.2 2015-11-04
EP15192870 2015-11-04
EP16150705.8 2016-01-11
EP16150705 2016-01-11
EP16000862 2016-04-15
EP16000862.9 2016-04-15
PCT/EP2016/060041 WO2016177802A1 (en) 2015-05-04 2016-05-04 Anti-cancer fusion polypeptide

Publications (1)

Publication Number Publication Date
KR20170138574A true KR20170138574A (ko) 2017-12-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177034820A Pending KR20170138574A (ko) 2015-05-04 2016-05-04 항암 융합 폴리펩타이드

Country Status (13)

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US (2) US10865250B2 (enExample)
EP (2) EP4378962A3 (enExample)
JP (1) JP6783797B2 (enExample)
KR (1) KR20170138574A (enExample)
CN (2) CN114316067A (enExample)
AU (1) AU2016258977C1 (enExample)
BR (1) BR112017020434A2 (enExample)
CA (1) CA2980840A1 (enExample)
MX (1) MX2017014083A (enExample)
RU (1) RU2727165C2 (enExample)
SG (1) SG11201708334RA (enExample)
WO (1) WO2016177802A1 (enExample)
ZA (1) ZA201705961B (enExample)

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HK1249526A1 (en) 2018-11-02
SG11201708334RA (en) 2017-11-29
CN107636014B (zh) 2021-12-07
US10865250B2 (en) 2020-12-15
EP4378962A3 (en) 2024-07-31
CA2980840A1 (en) 2016-11-10
ZA201705961B (en) 2023-12-20
US20210198380A1 (en) 2021-07-01
EP4378962A2 (en) 2024-06-05
JP2018515085A (ja) 2018-06-14
JP6783797B2 (ja) 2020-11-11
CN107636014A (zh) 2018-01-26
US20190010248A1 (en) 2019-01-10
BR112017020434A2 (pt) 2018-06-26
AU2016258977C1 (en) 2022-07-14
RU2017135596A (ru) 2019-06-04
CN114316067A (zh) 2022-04-12
AU2016258977A1 (en) 2017-11-30
MX2017014083A (es) 2018-11-09
RU2017135596A3 (enExample) 2019-09-16
EP3292148A1 (en) 2018-03-14
RU2727165C2 (ru) 2020-07-21
EP3292148B1 (en) 2024-01-24
AU2016258977B2 (en) 2022-03-17
WO2016177802A1 (en) 2016-11-10

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