AU2016258977C1 - Anti-cancer fusion polypeptide - Google Patents

Anti-cancer fusion polypeptide Download PDF

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Publication number
AU2016258977C1
AU2016258977C1 AU2016258977A AU2016258977A AU2016258977C1 AU 2016258977 C1 AU2016258977 C1 AU 2016258977C1 AU 2016258977 A AU2016258977 A AU 2016258977A AU 2016258977 A AU2016258977 A AU 2016258977A AU 2016258977 C1 AU2016258977 C1 AU 2016258977C1
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AU
Australia
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ser
lys
leu
asp
glu
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Ceased
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AU2016258977A
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English (en)
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AU2016258977A1 (en
AU2016258977B2 (en
Inventor
Rachida Siham Bel Aiba
Marlon HINNER
Thomas Jean Jaquin
Ulrich Moebius
Shane Olwill
Christine Rothe
Corinna SCHLOSSER
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Pieris Pharmaceuticals GmbH
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Pieris Pharmaceuticals GmbH
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Publication of AU2016258977B2 publication Critical patent/AU2016258977B2/en
Publication of AU2016258977C1 publication Critical patent/AU2016258977C1/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2016258977A 2015-05-04 2016-05-04 Anti-cancer fusion polypeptide Ceased AU2016258977C1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
EP15166179 2015-05-04
EP15166179.0 2015-05-04
EP15167917 2015-05-18
EP15167917.2 2015-05-18
EP15002702.7 2015-09-17
EP15002702 2015-09-17
EP15192870.2 2015-11-04
EP15192870 2015-11-04
EP16150705.8 2016-01-11
EP16150705 2016-01-11
EP16000862 2016-04-15
EP16000862.9 2016-04-15
PCT/EP2016/060041 WO2016177802A1 (en) 2015-05-04 2016-05-04 Anti-cancer fusion polypeptide

Publications (3)

Publication Number Publication Date
AU2016258977A1 AU2016258977A1 (en) 2017-11-30
AU2016258977B2 AU2016258977B2 (en) 2022-03-17
AU2016258977C1 true AU2016258977C1 (en) 2022-07-14

Family

ID=55948826

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016258977A Ceased AU2016258977C1 (en) 2015-05-04 2016-05-04 Anti-cancer fusion polypeptide

Country Status (13)

Country Link
US (2) US10865250B2 (enExample)
EP (2) EP4378962A3 (enExample)
JP (1) JP6783797B2 (enExample)
KR (1) KR20170138574A (enExample)
CN (2) CN114316067A (enExample)
AU (1) AU2016258977C1 (enExample)
BR (1) BR112017020434A2 (enExample)
CA (1) CA2980840A1 (enExample)
MX (1) MX2017014083A (enExample)
RU (1) RU2727165C2 (enExample)
SG (1) SG11201708334RA (enExample)
WO (1) WO2016177802A1 (enExample)
ZA (1) ZA201705961B (enExample)

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CN113939307A (zh) * 2019-03-29 2022-01-14 皮里斯制药有限公司 脂质运载蛋白突变蛋白的吸入施用
CN113677403B (zh) * 2019-04-12 2024-12-27 豪夫迈·罗氏有限公司 包含脂质运载蛋白突变蛋白的双特异性抗原结合分子
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Publication number Publication date
HK1249526A1 (en) 2018-11-02
SG11201708334RA (en) 2017-11-29
CN107636014B (zh) 2021-12-07
US10865250B2 (en) 2020-12-15
EP4378962A3 (en) 2024-07-31
CA2980840A1 (en) 2016-11-10
ZA201705961B (en) 2023-12-20
US20210198380A1 (en) 2021-07-01
EP4378962A2 (en) 2024-06-05
JP2018515085A (ja) 2018-06-14
JP6783797B2 (ja) 2020-11-11
CN107636014A (zh) 2018-01-26
KR20170138574A (ko) 2017-12-15
US20190010248A1 (en) 2019-01-10
BR112017020434A2 (pt) 2018-06-26
RU2017135596A (ru) 2019-06-04
CN114316067A (zh) 2022-04-12
AU2016258977A1 (en) 2017-11-30
MX2017014083A (es) 2018-11-09
RU2017135596A3 (enExample) 2019-09-16
EP3292148A1 (en) 2018-03-14
RU2727165C2 (ru) 2020-07-21
EP3292148B1 (en) 2024-01-24
AU2016258977B2 (en) 2022-03-17
WO2016177802A1 (en) 2016-11-10

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