KR20170069262A - Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물 - Google Patents

Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물 Download PDF

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KR20170069262A
KR20170069262A KR1020177012839A KR20177012839A KR20170069262A KR 20170069262 A KR20170069262 A KR 20170069262A KR 1020177012839 A KR1020177012839 A KR 1020177012839A KR 20177012839 A KR20177012839 A KR 20177012839A KR 20170069262 A KR20170069262 A KR 20170069262A
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smad7
day
antisense oligonucleotide
patient
seq
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지오반니 몬텔레온
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노그라 파마 리미티드
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    • C12Q2600/00—Oligonucleotides characterized by their use
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020177012839A 2014-10-17 2015-10-16 Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물 Withdrawn KR20170069262A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462065598P 2014-10-17 2014-10-17
US62/065,598 2014-10-17
PCT/EP2015/074066 WO2016059239A1 (en) 2014-10-17 2015-10-16 Methods and compositions for treating a subject with a smad7 antisense oligonucleotide

Publications (1)

Publication Number Publication Date
KR20170069262A true KR20170069262A (ko) 2017-06-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177012839A Withdrawn KR20170069262A (ko) 2014-10-17 2015-10-16 Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물

Country Status (12)

Country Link
US (2) US10337004B2 (enExample)
EP (1) EP3207136A1 (enExample)
JP (1) JP2017532961A (enExample)
KR (1) KR20170069262A (enExample)
CN (1) CN107406851A (enExample)
AU (1) AU2015332624A1 (enExample)
CA (1) CA2964667A1 (enExample)
EA (1) EA201790867A1 (enExample)
IL (1) IL251717A0 (enExample)
MA (1) MA43331A (enExample)
MX (1) MX2017004973A (enExample)
WO (1) WO2016059239A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
JP5719776B2 (ja) 2008-11-13 2015-05-20 ノグラ ファーマ リミテッド アンチセンス組成物およびその作製および使用
WO2013037970A1 (en) 2011-09-15 2013-03-21 Nogra Pharma Limited Methods for monitoring responsiveness to anti-smad7 therapy
NZ630914A (en) 2012-04-18 2017-01-27 Nogra Pharma Ltd Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
KR20170005058A (ko) 2014-05-09 2017-01-11 노그라 파마 리미티드 염증성 장 질환을 치료하는 방법
US20170233736A1 (en) * 2014-10-17 2017-08-17 Nogra Pharma Limited Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels
US10337004B2 (en) 2014-10-17 2019-07-02 Nogra Pharma Limited Methods and compositions for treating a subject with a SMAD7 antisense oligonucleotide
JP2019505598A (ja) * 2016-02-23 2019-02-28 セルジーン アルパイン インベストメント カンパニー Ｉｉ， エルエルシー Ｓｍａｄ７の阻害を用いて、腸線維症を治療する方法
WO2018122376A1 (en) * 2016-12-30 2018-07-05 Nogra Pharma Limited Compositions of smad7 antisense oligonucleotide and methods of treating or preventing psoriasis
EP4139459A2 (en) * 2020-04-24 2023-03-01 Nogra Pharma Limited Compositions of smad7 antisense oligonucleotides (aso) and methods of using the same

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1456380B1 (en) 2001-11-02 2012-04-18 Giuliani International Limited Smad7 inhibitors for the treatment of cns diseases
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
JP5719776B2 (ja) 2008-11-13 2015-05-20 ノグラ ファーマ リミテッド アンチセンス組成物およびその作製および使用
CA2750584A1 (en) * 2009-01-26 2010-07-29 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Means and methods for modulating notch3 protein expression and/or the coding region of notch3; compositions and use thereof in the treatment of cadasil
US9006198B2 (en) * 2010-02-08 2015-04-14 Isis Pharmaceuticals, Inc. Selective reduction of allelic variants
WO2013037970A1 (en) * 2011-09-15 2013-03-21 Nogra Pharma Limited Methods for monitoring responsiveness to anti-smad7 therapy
NZ630914A (en) 2012-04-18 2017-01-27 Nogra Pharma Ltd Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation
JP6502863B2 (ja) 2013-03-15 2019-04-17 ノグラ ファーマ リミテッド 結腸直腸癌を処置する方法
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
KR20170005058A (ko) 2014-05-09 2017-01-11 노그라 파마 리미티드 염증성 장 질환을 치료하는 방법
JP2017532982A (ja) 2014-10-17 2017-11-09 セルジーン アルパイン インベストメント カンパニー Ｉｉ， エルエルシー Ｓｍａｄ７アンチセンスオリゴヌクレオチドの同位体置換体
US10337004B2 (en) 2014-10-17 2019-07-02 Nogra Pharma Limited Methods and compositions for treating a subject with a SMAD7 antisense oligonucleotide
US20170233736A1 (en) 2014-10-17 2017-08-17 Nogra Pharma Limited Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels
MA41271A (fr) 2014-12-26 2017-10-31 Celgene Alpine Invest Company Ii Llc Méthodes d'utilisation d'oligonucléotides antisens ciblant smad7
EP3356530A4 (en) 2015-09-30 2019-04-10 Celgene Alpine Investment Company II, LLC TLR-MODULATORS AND METHOD OF USE
EP3355896A2 (en) 2015-09-30 2018-08-08 Nogra Pharma Limited Methods of using smad7 antisense oligonucleotides based on biomarker expression

Also Published As

Publication number Publication date
WO2016059239A1 (en) 2016-04-21
MX2017004973A (es) 2017-12-07
AU2015332624A1 (en) 2017-05-04
EA201790867A1 (ru) 2017-08-31
JP2017532961A (ja) 2017-11-09
CA2964667A1 (en) 2016-04-21
EP3207136A1 (en) 2017-08-23
US20170240893A1 (en) 2017-08-24
US20190338283A1 (en) 2019-11-07
MA43331A (fr) 2017-08-23
CN107406851A (zh) 2017-11-28
IL251717A0 (en) 2017-06-29
US10337004B2 (en) 2019-07-02

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