KR20170069262A - Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물 - Google Patents

Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물 Download PDF

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KR20170069262A
KR20170069262A KR1020177012839A KR20177012839A KR20170069262A KR 20170069262 A KR20170069262 A KR 20170069262A KR 1020177012839 A KR1020177012839 A KR 1020177012839A KR 20177012839 A KR20177012839 A KR 20177012839A KR 20170069262 A KR20170069262 A KR 20170069262A
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smad7
day
antisense oligonucleotide
patient
seq
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지오반니 몬텔레온
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노그라 파마 리미티드
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020177012839A 2014-10-17 2015-10-16 Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물 Withdrawn KR20170069262A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462065598P 2014-10-17 2014-10-17
US62/065,598 2014-10-17
PCT/EP2015/074066 WO2016059239A1 (en) 2014-10-17 2015-10-16 Methods and compositions for treating a subject with a smad7 antisense oligonucleotide

Publications (1)

Publication Number Publication Date
KR20170069262A true KR20170069262A (ko) 2017-06-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020177012839A Withdrawn KR20170069262A (ko) 2014-10-17 2015-10-16 Smad7 안티센스 올리고뉴클레오티드로 대상체를 치료하기 위한 방법 및 조성물

Country Status (12)

Country Link
US (2) US10337004B2 (enExample)
EP (1) EP3207136A1 (enExample)
JP (1) JP2017532961A (enExample)
KR (1) KR20170069262A (enExample)
CN (1) CN107406851A (enExample)
AU (1) AU2015332624A1 (enExample)
CA (1) CA2964667A1 (enExample)
EA (1) EA201790867A1 (enExample)
IL (1) IL251717A0 (enExample)
MA (1) MA43331A (enExample)
MX (1) MX2017004973A (enExample)
WO (1) WO2016059239A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
PL2364360T3 (pl) 2008-11-13 2017-09-29 Nogra Pharma Limited Antysensowne kompozycje i sposoby ich wytwarzania i stosowania
CA2848595A1 (en) 2011-09-15 2013-03-21 Nogra Pharma Limited Methods for monitoring responsiveness to anti-smad7 therapy
US10081809B2 (en) 2012-04-18 2018-09-25 University Of Miami Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
KR20170005058A (ko) 2014-05-09 2017-01-11 노그라 파마 리미티드 염증성 장 질환을 치료하는 방법
MX2017004973A (es) 2014-10-17 2017-12-07 Nogra Pharma Ltd Metodos y composiciones para tratar a un sujeto con un oligonucleotido antisentido de smad7.
CA2964673A1 (en) * 2014-10-17 2016-04-21 Nogra Pharma Limited Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels
WO2017147276A1 (en) 2016-02-23 2017-08-31 Celgene Corporation Methods of treating intestinal fibrosis using smad7 inhibition
WO2018122376A1 (en) * 2016-12-30 2018-07-05 Nogra Pharma Limited Compositions of smad7 antisense oligonucleotide and methods of treating or preventing psoriasis
JP2023522389A (ja) * 2020-04-24 2023-05-30 ノグラ ファーマ リミテッド Ｓｍａｄ７アンチセンスオリゴヌクレオチド（ａｓｏ）の組成物およびその使用方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2388968T3 (es) 2001-11-02 2012-10-22 Giuliani International Limited Inhibidores de Smad7 para el tratamiento de enfermedades del SNC
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
PL2364360T3 (pl) 2008-11-13 2017-09-29 Nogra Pharma Limited Antysensowne kompozycje i sposoby ich wytwarzania i stosowania
US9062311B2 (en) * 2009-01-26 2015-06-23 Academisch Ziekenhuis Leiden H.O.D.N. Lumc Means and methods for modulating NOTCH3 protein expression and/or the coding region of NOTCH3; compositions and use thereof in the treatment of CADASIL
WO2011097644A2 (en) * 2010-02-08 2011-08-11 Isis Pharmaceuticals, Inc. Selective reduction of allelic variants
CA2848595A1 (en) * 2011-09-15 2013-03-21 Nogra Pharma Limited Methods for monitoring responsiveness to anti-smad7 therapy
US10081809B2 (en) 2012-04-18 2018-09-25 University Of Miami Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
EP2970419B8 (en) 2013-03-15 2019-12-11 Nogra Pharma Limited Methods of treating colorectal cancer
KR20170005058A (ko) 2014-05-09 2017-01-11 노그라 파마 리미티드 염증성 장 질환을 치료하는 방법
WO2015011694A2 (en) 2014-10-17 2015-01-29 Celgene Corporation Isotopologues of smad7 antisense oligonucleotides
CA2964673A1 (en) 2014-10-17 2016-04-21 Nogra Pharma Limited Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels
MX2017004973A (es) 2014-10-17 2017-12-07 Nogra Pharma Ltd Metodos y composiciones para tratar a un sujeto con un oligonucleotido antisentido de smad7.
MA41271A (fr) 2014-12-26 2017-10-31 Celgene Alpine Invest Company Ii Llc Méthodes d'utilisation d'oligonucléotides antisens ciblant smad7
CA3000569A1 (en) 2015-09-30 2017-04-06 Nogra Pharma Limited Methods of using smad7 antisense oligonucleotides based on biomarker expression
JP2018529726A (ja) 2015-09-30 2018-10-11 セルジーン アルパイン インベストメント カンパニー Ｉｉ， エルエルシー Ｔｌｒ調節因子及び使用方法

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Publication number Publication date
WO2016059239A1 (en) 2016-04-21
EP3207136A1 (en) 2017-08-23
MX2017004973A (es) 2017-12-07
US20190338283A1 (en) 2019-11-07
EA201790867A1 (ru) 2017-08-31
CA2964667A1 (en) 2016-04-21
CN107406851A (zh) 2017-11-28
US10337004B2 (en) 2019-07-02
US20170240893A1 (en) 2017-08-24
IL251717A0 (en) 2017-06-29
AU2015332624A1 (en) 2017-05-04
JP2017532961A (ja) 2017-11-09
MA43331A (fr) 2017-08-23

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Patent event date: 20170512

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