KR20170058546A - Cosmetic Composition for Reducing Skin Wrinkle - Google Patents

Abstract

The present invention relates to a composition for skin external application and a cosmetic composition for promoting collagen biosynthesis, comprising a complex essential oil, as an active ingredient. The composition, by promoting collagen synthesis, can alleviate skin wrinkles, and can have effects of keeping the skin more firm and elastic.

Description

[0001] Cosmetic Composition for Reducing Skin Wrinkle [

The present invention relates to a composition for external application for skin and a cosmetic composition for promoting collagen production, which comprises a whitening essential oil, a lavender essential oil, a rosemary essential oil, a geranium essential oil and a complex essential oil of bay oil.

Skin is the largest tissue in the epidermal system consisting of multiple epithelial tissues that protects the muscles and organs in the body and plays an important role in maintaining the body's homeostasis by protecting the inside of the body from the external environment. As a result, the skin is exposed to external physical and chemical stimuli, stress, nutritional deficiencies, such as the normal function of the skin degraded, elasticity and wrinkles, such as skin aging phenomenon is promoted.

Skin aging can be divided into innate age and extrinsic age. The above-mentioned internal aging is an aging caused by an increase in age, and aging resulting from a decrease in the physiological function of the body. The external aging refers to the aging phenomenon caused by external ultraviolet rays, active oxygen, stress, and the like. These internal and external aging factors aging the skin promote wrinkles on the skin surface, resulting in rough skin texture and reduced elasticity.

According to the mechanism of wrinkle formation, the collagen (collagen) and elastin in the dermis continue to be decomposed and produced. If the supplement after the decomposition is not smooth, the skin loses elasticity and wrinkles .

Retinoic acid, retinol, ascorbic acid, and? -Hydroxy acid are among the representative anti-wrinkle and anti-aging substances reported so far.

Retinoic acid inhibits lipid per-oxidation and ornithine decarboxylase response. However, it is sensitive to ultraviolet rays and has a high irritation, so it has been reported that side effects of redness of the skin have been reported, and its use is restricted.

Retinol is less effective for wrinkle improvement than retinoic acid, but is widely used because of its relatively high safety. However, when retinol is used at a high concentration, skin irritation occurs, skin pigmentation occurs upon exposure to ultraviolet rays, and oxidation is easily caused by oxygen, heat and light in the air.

Ascorbic acid is easily oxidized by the external environment such as air, water, and high temperature, and thus the activity is greatly reduced, thereby lowering the degree of wrinkle improvement and causing discoloration and deterioration of the formulation.

Although α-hydroxy acid is also disclosed as an anti-wrinkle agent, there are side effects of skin irritation such as itching, erythema, and sensitivity to ultraviolet rays, thereby causing a problem of safety of the product.

In addition, cosmetic products containing sunscreen agents, moisturizers, and antioxidants are widely used to prevent wrinkles, but the effect of wrinkles on these products is minimal.

On the other hand, essential oil is extracted from the fruit, leaf, flower, stem, bark and root of the existing tree and named after the extracted plant. Essential oils extracted from plants are a mixture of monoerpene and phenolic compounds which are not a single chemical component but strong volatile components. The genetic characteristics of the extracted plant species and the composition of the essential oil components are different according to the environment and harvesting season in the cultivation area. These essential oils do not directly affect the growth and differentiation of plants, but they have various functions and are widely used in medicines, fragrances, household goods and the like.

For example, Korean Patent Laid-Open Publication No. 2014-0062958 discloses an aroma oil composition and a cosmetic composition having body fat or cellulite reducing and preventing effect including an essential oil fraction extracted from a sesamin extract, and a cosmetic composition for preventing and improving depression Lt; / RTI >

Korean Patent Publication No. 2014-0062958

The present inventors have found that when a complex essential oil, which is used as a raw material for a variety of aromatherapy and fragrance materials, is applied to the skin substantially, the effect of the essential oil, The present inventors have completed the present invention by confirming that collagen production is promoted when used together, and that the effect of improving skin wrinkles is exhibited.

Accordingly, it is an object of the present invention to provide a composition for promoting collagen synthesis, which comprises, as an active ingredient, a whitening essential oil, a lavender essential oil, a rosemary essential oil, a geranium essential oil and a complex essential oil of bay oil.

It is another object of the present invention to provide a cosmetic composition for improving wrinkles comprising a whitening essential oil, a lavender essential oil, a rosemary essential oil, a geranium essential oil and a complex essential oil of bay oil as an active ingredient

In order to achieve the above object,

A composition for external application for skin for promoting collagen biosynthesis, which comprises, as an active ingredient, a complex essential oil of whitening essential oil, lavender essential oil, rosemary essential oil, geranium essential oil and bay oil.

Also,

The present invention provides a cosmetic composition for improving wrinkles containing as an active ingredient a whitening essential oil, a lavender essential oil, a rosemary essential oil, a geranium essential oil and a complex essential oil of bay oil.

The external application composition and cosmetic composition according to the present invention act on fibroblasts of the dermal layer to promote collagen production, and thus can be usefully used for preventing or improving skin wrinkles, skin elasticity, or aging.

FIG. 1 is a graph showing cytotoxicity results of a white cotton essential oil against human skin fibroblasts.
2 is a graph showing the activity of increasing the collagen production in the dermis fibroblasts of the whitening essential oil (blue bar: after 24 hours, red bar: after 48 hours).
3 is a graph showing cytotoxicity results of lavender essential oil against human skin fibroblasts.
4 is a graph showing collagen production-increasing activity of lavender essential oil in dermal fibroblasts.
5 is a graph showing cytotoxicity results of rosemary essential oil against human skin fibroblasts.
6 is a graph showing the activity of increasing the collagen production in the dermal fibroblast of rosemary essential oil.
7 is a graph showing cytotoxicity results of geranium essential oil against human skin fibroblasts.
8 is a graph showing collagen production-increasing activity of geranium essential oil in dermis fibroblasts.
FIG. 9 is a graph showing the cytotoxicity results of the bay for human skin fibroblasts.
FIG. 10 is a graph showing collagen production-increasing activity in dermal fibroblasts of the beverage.
FIG. 11 is a graph showing collagen production-increasing activity in dermis fibroblasts of waxy essential oil, lavender essential oil, rosemary essential oil, betaine, geranium essential oil and complex essential oil (blue bar: after 24 hours, red bar: after 48 hours) .
FIG. 12 is a graph showing collagen production-increasing activity in dermal fibroblasts after culturing for 48 hours after treatment with each of plain white essential oil, lavender essential oil, rosemary essential oil, betaine, geranium essential oil and complex essential oil.

Lavender essential oil, rosemary essential oil, bean oil and geranium essential oil used as an active ingredient in the present invention can be separated by conventional extraction methods, distillation or compression, or commercially available , And the method of extracting the essential oil is omitted in the present invention.

The whitening essential oil is extracted from flowers, leaves, stems and roots of Chamaecyparis obtusa, and its direction, insecticidal, antibacterial and antioxidative effects are known.

The lavender essential oil is selected from the group consisting of Lavandula angustifolia ), which have been used for antibacterial, sedative, antidepressant and skin wounds.

The rosemary essential oil is rosemary ( Rosmarinus officinalis ) It is a natural fragrance which is extracted from the whole ground part of the plant and has a good antiseptic, antibacterial and astringent effect.

The geranium essential oil is selected from the group consisting of geranium Graveolens ) is known to relieve the pain of neuralgia at the time of topical application, and has been mainly used as a flavoring agent and a fragrance.

The bay oil is available from Pimenta < RTI ID = 0.0 > racemosa ) leaves, which have been used for antimicrobial and anti-inflammatory actions to relieve bronchitis and relax muscles.

According to one embodiment of the present invention, a complex essential oil of a white essential oil, a lavender essential oil, a rosemary essential oil, a beige and a geranium essential oil is selected from the group consisting of linseed oil: lavender essential oil: rosemary essential oil: geranium essential oil: : 450 to 550: 0.5 to 1.5: 450 to 550. Such a content ratio is preferably maintained within the above-mentioned range so as to secure the effect to be obtained in the present invention, which alleviates the wrinkles of the skin and improves the skin firmly and resiliently.

In addition, the composition according to the present invention may contain, in addition to the above-mentioned complex essential oil, other components which can give a synergistic effect to the main effect, within a range not impairing the intended main effect of the present invention.

Experimental Example 11 according to the present invention was conducted to examine the collagen synthesis effect of the complex essential oil. As a result, the amount of collagen synthesis in the skin dermal fibroblast was further increased during the complex refining treatment than when each essential oil was used alone.

These results show that the complex essential oil of the present invention can be applied as a composition for external application for skin and a cosmetic composition and can promote collagen synthesis when applied to the skin, thereby further alleviating the wrinkles of the skin, The effect can be obtained.

The complex essential oil may contain 0.0001 to 30.0% by weight, preferably 0.001 to 30.0% by weight, based on the weight of the total external preparation composition. If the content of the compound is below the recommended range, no significant effect can be expected. On the contrary, if the content exceeds the recommended range, the effect is not increased as compared with the increase of the content, and slight cytotoxicity may be caused.

The external preparation composition is not particularly limited in its formulation and may be, for example, an external preparation composition having a formulation of a body lotion, ointment, gel, cream, patch or spray. At this time, in the composition for external application for each formulation, ingredients other than the complex essential oil can be mixed and selected by those skilled in the art according to the formulation or purpose of use of the other external preparation.

In particular, the complex essential oil according to the present invention can be applied as a cosmetic composition containing it as an active ingredient through promoting collagen synthesis.

The complex essential oil may contain 0.0001 to 30.0% by weight, preferably 0.001 to 30.0% by weight, based on the total weight of the cosmetic composition. If the content of the compound is below the recommended range, no significant effect can be expected. On the other hand, if the content of the compound exceeds the above range, the effect is not increased as compared with the content of the compound, and slight cytotoxicity may be exhibited.

The composition of the cosmetic composition is not particularly limited in its formulation and may be in the form of a lotion such as a lotion, a milky lotion, a cream, a foam, an essence, a serum, a soft water, an emulsion, a foundation, a makeup base, a soap, ≪ / RTI >

In addition, the compositions of each formulation may contain various bases and additives necessary for formulation of the formulation, and may contain non-ionic surfactants, silicone polymers, extender pigments, flavorings, preservatives, But are not limited to, disinfectants, oxidative stabilizers, organic solvents, ionic or nonionic thickeners, plasticizers, antioxidants, free radical scavengers, opacifiers, stabilizers, emollients, silicones, A preservative, a surfactant, an anti-inflammatory agent, a substance P antagonist, a filler, a polymer, a propellant, a basicizing or acidifying agent, or a coloring agent.

Hereinafter, preferred embodiments of the present invention will be described in order to facilitate understanding of the present invention. However, the following examples are provided to further understand the present invention, and the present invention is not limited by the examples.

Experimental Example  1: Confirmation of cytotoxicity of white essential oil

1. Culture of human skin fibroblasts

Human dermal fibroblast was purchased from Gibco (Life Technologies, Carlsbad, Calif., USA). The cells were cultured in DMEM medium (Gibco) at 37 ° C. The medium was maintained until the adhered cells were confluent at 80% and subcultured at 80% confluence. The medium was replaced every two days until confluence. For the subculture, the flask in which the culture solution had been removed was washed with phosphate buffered saline (PBS), and the cells were suspended in 0.25% trypsin-EDTA (Gibco BRL, Grand Island, NY, USA) After that, the number of cells was measured and subcultured again in the culture solution three times.

2. Cytotoxicity measurement

DMEM medium (Gibco) supplemented with 10% serum was added to each well of a 96-well plate, human fibroblasts were inoculated with 5 x 10 ² cells, cultured at 5% CO ₂ and 37 ° C, Then, the cells were cultured in a serum-free medium for 24 hours, and then divided into a negative control (DMSO treatment) and a whitening oil treatment group. The whitening essential oil was dissolved in DMSO at a concentration of 10 μl (treatment concentration 0.0001 wt% to 0.1 wt%).

After the treatment, the cells were cultured at 5% CO ₂ and 37 ° C for 24 hours. After 4 hours, MTT reagent was added and the medium was removed. 200 μl of DMSO was added to dissolve the formazan crystal, and the absorbance was measured at 570 nm with a microplate reader. The results are shown in Fig.

From the results shown in FIG. 1, it can be seen from the results of the control group that there is no cytotoxicity at a final concentration of 0.1 wt% or less under the conditions of the treatment with the whitening oil, and that the cell proliferation increases by about 2 to 7% there was.

Experimental Example  2: Increase in the amount of collagen synthesis in the dermis fibroblasts by the whitening oil

Collagen measurement experiment was carried out to examine the effects of the white essential oil on the amount of collagen synthesis in the dermal fibroblast. Dermal fibroblast cells were added to DMEM medium supplemented with 10% fetal bovine serum, 100 U / ml penicillin, and 100 μg / ml streptomycin, and cultured at 37 ° C and 5% CO ₂ . After 1 day of culture, the culture medium was changed to 0.01% and 0.001 wt% of the cotton wool, and cultured for 24 hours and 48 hours, respectively. The wells were washed 3 times with PBS, and 100 쨉 l of antibody-POD conjugate solution was added to the wells and left at 37 째 C for 1 hour. The wells were washed three times with PBS, and 100 μl of the substrate solution (TMB) was added to the wells and left at 25 ° C for 30 minutes. 1N H ₂ SO ₄ was added to the well and the absorbance of the collagen was measured at 450 nm using an ELISA reader (Bio-Tek instrument). At this time, the activity of increasing collagen production was calculated according to the difference in absorbance relative to the control group treated with DMSO, and the results were derived. The results are shown in Fig.

Referring to FIG. 2, when the degree of collagen synthesis was measured, about 120% collagen synthesis amount was shown at a concentration of 0.01 wt% for 24 hours of monoaxial essential oil treatment, and collagen synthesis amount was increased at other concentrations. However, the amount of collagen synthesis decreased after 48 hours of treatment with white essential oil. This suggests that the effect of promoting the collagen synthesis of the monoaxial essential oil is very fast and disappears.

Experimental Example  3: Cytotoxicity of lavender essential oil

The cytotoxicity of lavender essential oil to human skin fibroblasts was confirmed in the same manner as in Experimental Example 1, and the results are shown in FIG.

From the results shown in FIG. 3, it can be seen that when the control group is used as a reference, the cells are not cytotoxic at a final concentration of 0.05% or less under the conditions of the lavender essential oil treatment of the present invention, and the cell proliferation is increased by about 20% .

Experimental Example  4: Increased amount of collagen synthesis in dermal fibroblast by lavender essential oil

In the same manner as in Experimental Example 2, the effect of increasing the collagen synthesis in the dermal fibroblasts of lavender essential oil was confirmed, and the results are shown in FIG.

Referring to FIG. 4, about 126% collagen synthesis amount was shown when 0.0001 wt% of Lavender essential oil was treated for 24 hours, and the amount of collagen synthesis decreased to about 91% when treated for 48 hours. It was found that the collagen synthesis promoting effect of lavender essential oil was very fast and disappeared.

Experimental Example  5: Rosemary  To check cytotoxicity of essential oil

The cytotoxicity of rosemary essential oil to human skin fibroblast was confirmed in the same manner as in Experimental Example 1, and the results are shown in FIG.

As shown in FIG. 5, when the control group was used as a reference, the cells were not cytotoxic at a final concentration of 0.1% or less under the condition of the rosemary essential oil treatment, and the cell proliferation was increased by about 10% at a total concentration.

Experimental Example  6: Rosemary  Increased amount of collagen synthesis in dermal fibroblast by essential oil

The effect of increasing the collagen synthesis in the dermal fibroblasts of rosemary essential oil was confirmed in the same manner as in Experimental Example 2, and the results are shown in FIG.

Referring to FIG. 6, when 0.01 wt% and 0.005 wt% of rosemary essential oil were treated for 24 hours, the amount of collagen synthesis was about 130% at a concentration of 0.005 wt%. However, when rosemary essential oil was treated for 48 hours, the amount of collagen synthesis decreased. It was found that the promoting effect of collagen synthesis of rosemary essential oil was very fast and disappeared.

Experimental Example  7: Cytotoxicity of geranium essential oil

The cytotoxicity of geranium essential oil to human skin fibroblasts was confirmed in the same manner as in Experimental Example 1, and the results are shown in FIG.

From the results shown in FIG. 7, it can be seen that the cell proliferation is increased at a very low concentration of about 135% at the final concentration of 0.01 wt% or less under the condition of the geranium essential oil treatment based on the control group.

Experimental Example  8. Increased amount of collagen synthesis in dermis fibroblast by geranium essential oil

The effect of increasing the collagen synthesis in the dermal fibroblasts of rosemary essential oil was confirmed in the same manner as in Experimental Example 2, and the results are shown in FIG.

As shown in Fig. 8, the amount of collagen synthesis was about 130% when 0.00001 wt% of geranium essential oil was treated for 24 hours, and the amount of collagen synthesis was not changed when treated for 48 hours. This suggests that the promoting effect of collagen synthesis of geranium essential oil is very fast and disappears.

Experimental Example  9: Bay  Cytotoxicity check

The cytotoxicity of human dermal fibroblasts in the beak was confirmed by the same method as in Experimental Example 1, and the results are shown in FIG.

From the results shown in FIG. 9, it can be seen that when the control group is used as a reference, the cells are not cytotoxic at a final concentration of 0.005 wt% or less under the treatment of bean, and the cell proliferation is increased by about 10% at a very low concentration.

Experimental Example  10: On the bayou  Of collagen synthesis in dermal fibroblast

In the same manner as in Experimental Example 2, the effect of increasing collagen synthesis in the dermal fibroblast of the beverage was confirmed, and the results are shown in FIG.

Referring to FIG. 10, when the degree of collagen synthesis was measured, about 104% of collagen synthesis was observed when the bean was treated at 0.0005 wt% for 24 hours, Was increased by about 140%. This indicates that the collagen synthesis effect is increased when the bean is continuously used.

Experimental Example  11: Increase in the amount of collagen synthesis in the dermis fibroblasts of the complex essential oil

In order to investigate the effect of the four essential oils and the beef oil on the amount of collagen synthesis in dermal fibroblasts, a collagen measurement experiment was carried out using a mixture of five kinds of essential oils. Dermal fibroblast cells were added to DMEM medium supplemented with 10% fetal bovine serum, 100 U / ml penicillin, and 100 μg / ml streptomycin, and cultured at 37 ° C and 5% CO ₂ . After culturing for 1 day, they were cultivated for 24 hours and 48 hours, respectively, with a mixture of five kinds of essential oils (0.01 wt% of essential oil, 0.0001 wt% of lavender essential oil, 0.005 wt% of rosemary, 0.00001 wt% of geranium and 0.005 wt% of bean) . The wells were washed 3 times with PBS, and 100 쨉 l of antibody-POD conjugate solution was added to the wells and left at 37 째 C for 1 hour. The wells were washed three times with PBS, and 100 μl of the substrate solution (TMB) was added to the wells and left at 25 ° C for 30 minutes. 1N H ₂ SO ₄ was added to the well and the absorbance of the collagen was measured at 450 nm using an ELISA reader (Bio-Tek instrument). At this time, the activity of increasing collagen production was calculated according to the difference in absorbance relative to the control group treated with DMSO, and the results were derived. The results are shown in FIG. 11 and FIG.

Referring to FIGS. 11 and 12, the amount of collagen synthesis was higher when each essential oil was mixed and applied than when treated alone. This indicates that the use of a mixture of essential oils with collagen synthesis ability can increase the amount of collagen synthesis in the dermal fibroblasts of the skin, compared with the use of each essential oil alone. Especially, the amount of collagen synthesis decreased 48 hours after mono - treatment of mono - faced essential oil, lavender essential oil, rosemary essential oil and geranium essential oil, but the amount of collagen synthesis was increased 48 hours after the treatment of complex refining.

Hereinafter, a preferred formulation example is provided to facilitate understanding of the present invention. However, the following formulation examples are provided only for a better understanding of the present invention, and the present invention is not limited by the formulation examples.

Formulation Example  1: Softening longevity ( skin )

The softening water containing the complex essential oil was prepared according to a conventional method as shown in Table 1 below. At this time, the complex essential oil was a mixture of the whitening essential oil: lavender essential oil: rosemary essential oil: geranium essential oil: beige at a weight ratio of 9: 0.09: 4.5: 0.009: 4.5.

ingredient Content (% by weight) Complex refinery 0.3 glycerin 5.0 1,3-butylene glycol 3.0 Betaine 1.0 Allantoin 0.1 EDTA-2Na 0.02 Sodium hyaruronate powder 0.05 ethanol 5.0 Octyldodec-16 0.2 Polyoxyethylene hardened castor oil 0.2 antiseptic Suitable amount Purified water Balance Sum 100

Formulation Example  2: Nourishing lotion (lotion)

A nutritional lotion containing a complex essential oil was prepared according to a conventional method as shown in Table 2 below. At this time, the complex essential oil was a mixture of the whitening essential oil: lavender essential oil: rosemary essential oil: geranium essential oil: beige at a weight ratio of 9: 0.09: 4.5: 0.009: 4.5.

ingredient Content (% by weight) Complex refinery 0.5 Glyceryl stearate SE 1.5 Cetearyl alcohol 1.0 Sheer butter 1.5 Polysorbate 60 1.3 Sorbitan stearate 0.5 Hardened vegetable oil 1.0 Mineral oil 5.0 Squalane 3.0 Cyclomethicone 2.0 Dimethicone 0.8 Tocopheryl acetate 0.5 Carbomer 0.12 glycerin 5.0 1,3-butylene glycol 3.0 Sodium hyaruronate powder 0.05 Triethanolamine 0.12 antiseptic Suitable amount Purified water Balance Sum 100

Formulation Example  3: Massage cream

A massage cream containing a complex essential oil was prepared according to a conventional method as shown in Table 3 below. At this time, the complex essential oil was a mixture of the whitening essential oil: lavender essential oil: rosemary essential oil: geranium essential oil: beige at a weight ratio of 9: 0.09: 4.5: 0.009: 4.5.

ingredient Content (% by weight) Complex refinery 0.5 Glycerin monostearate 1.5 Cetearyl alcohol 1.5 Stearic acid 1.0 Polysorbate 60 1.5 Sorbitan stearate 0.6 Isostearyl isoserate 5.0 Squalane 5.0 Mineral oil 35.0 Dimethicone 0.5 Hydroxyethylcellulose 0.12 glycerin 6.0 1,3-butylene glycol 3.0 Triethanolamine 0.3 antiseptic Suitable amount Purified water Balance Sum 100

Formulation Example  4: essence

Essences containing a complex essential oil were prepared according to a conventional method as shown in Table 4 below. At this time, the complex essential oil was a mixture of the whitening essential oil: lavender essential oil: rosemary essential oil: geranium essential oil: beige at a weight ratio of 9: 0.09: 4.5: 0.009: 4.5.

ingredient Content (% by weight) Complex refinery 0.5 glycerin 6.0 Betaine 5.0 PEG 1500 2.0 Allantoin 0.1 EDTA-2Na 0.02 Hydrogenated lecithin 0.6 Hydroxyethylcellulose 0.1 Sodium hyaruronate powder 0.08 Carboxyvinyl polymer 0.2 Triethanolamine 0.2 Ceramide 0.2 Octyldodecanol 3.0 Squalane 3.0 Polysorbate 60 0.4 Glyceryl stearate SE 1.5 antiseptic Suitable amount Purified water Balance Sum 100

Formulation Example  5: Ointment

An ointment containing a complex essential oil was prepared according to a conventional method as shown in Table 5 below. At this time, the complex essential oil was a mixture of the whitening essential oil: lavender essential oil: rosemary essential oil: geranium essential oil: beige at a weight ratio of 9: 0.09: 4.5: 0.009: 4.5.

ingredient Content (% by weight) Purified water Balance Complex refinery 0.5 glycerin 8.0 Butylene glycol 4.0 Liquid paraffin 15.0 Carbomer 0.1 Caprylic / capric triglyceride 3.0 Squueline 1.0 Cetearyl glucoside 1.5 Sorbitan stearate 0.4 Cetearyl alcohol 1.0 Wax 4.0

Claims (9)

A composition for external application for skin for promoting biosynthesis of collagen, which comprises as an active ingredient, a white essential oil, a lavender essential oil, a rosemary essential oil, a geranium essential oil, and a bay essential oil. The method according to claim 1, wherein the complex essential oil is a mixture of linseed oil, lavender essential oil, rosemary essential oil, geranium essential oil, and betaine essential oil at a weight ratio of 500-1500: 8-12: 450-550: 0.5-1.5: 450-550 Wherein the collagen biosynthesis promoting composition is a composition for external application to skin for promoting collagen biosynthesis. The composition for external application for collagen biosynthesis according to claim 1 or 2, wherein the composition comprises a complex essential oil in an amount of 0.0001 to 30.0% by weight based on the total weight of the composition. The composition for external application for skin for promoting collagen biosynthesis according to claim 1 or 2, wherein the composition for promoting collagen production is an ointment, a gel, a cream, a patch or a spray. A cosmetic composition for improving wrinkles comprising an essential ingredient of a complex essential oil of linseed oil, linseed oil, lavender essential oil, rosemary essential oil, beige and geranium essential oil. [5] The method of claim 5, wherein the complex essential oil is a mixture of plain white essential oil, lavender essential oil, rosemary essential oil, geranium essential oil and betaine essential oil in a weight ratio of 500 to 1500: 8 to 12: 450 to 550: 0.5 to 1.5: 450 to 550 Wherein the cosmetic composition is a cosmetic composition for improving wrinkles. The cosmetic composition for wrinkle improvement according to claim 5 or 6, wherein the complex essential oil has an effect of promoting collagen synthesis. The cosmetic composition for improving wrinkles according to claim 5 or 6, wherein the composition contains a complex essential oil in an amount of 0.0001 to 30.0% by weight based on the total weight of the composition. The cosmetic composition for wrinkle improvement according to claim 5 or 6, wherein the wrinkle improving cosmetic composition is at least one selected from the group consisting of lotion, milky lotion, cream, foam, essence, serum, soft water, emulsion, foundation, makeup base, soap, sunscreen cream, Wherein the cosmetic composition has one type of formulation selected.

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