KR20170039152A - 신규 항생제 - Google Patents
신규 항생제 Download PDFInfo
- Publication number
- KR20170039152A KR20170039152A KR1020177002324A KR20177002324A KR20170039152A KR 20170039152 A KR20170039152 A KR 20170039152A KR 1020177002324 A KR1020177002324 A KR 1020177002324A KR 20177002324 A KR20177002324 A KR 20177002324A KR 20170039152 A KR20170039152 A KR 20170039152A
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- South Korea
- Prior art keywords
- compound
- cyclic structure
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- present
- streptococcus
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- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 description 1
- 239000004034 viscosity adjusting agent Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/16—Eight-membered rings
- C07D313/18—Eight-membered rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14179150 | 2014-07-30 | ||
| EP14179150.9 | 2014-07-30 | ||
| PCT/NL2015/050556 WO2016018153A1 (en) | 2014-07-30 | 2015-07-30 | Novel antibiotic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20170039152A true KR20170039152A (ko) | 2017-04-10 |
Family
ID=51265521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020177002324A Withdrawn KR20170039152A (ko) | 2014-07-30 | 2015-07-30 | 신규 항생제 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US9920025B2 (https=) |
| EP (1) | EP3174867B1 (https=) |
| JP (1) | JP2017528425A (https=) |
| KR (1) | KR20170039152A (https=) |
| WO (1) | WO2016018153A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10508095B2 (en) * | 2017-01-27 | 2019-12-17 | Koninklijke Nederlandse Akademie Van Wetenschappen | Method for producing antibiotic from pleosporaceae ulocladium |
| CN111333606B (zh) * | 2020-04-20 | 2022-05-10 | 大连医科大学附属第一医院 | 降碳倍半萜类化合物、制备方法及作为抗肿瘤药物的应用 |
-
2015
- 2015-07-30 WO PCT/NL2015/050556 patent/WO2016018153A1/en not_active Ceased
- 2015-07-30 KR KR1020177002324A patent/KR20170039152A/ko not_active Withdrawn
- 2015-07-30 US US15/329,758 patent/US9920025B2/en not_active Expired - Fee Related
- 2015-07-30 EP EP15767346.8A patent/EP3174867B1/en active Active
- 2015-07-30 JP JP2017501406A patent/JP2017528425A/ja active Pending
Non-Patent Citations (8)
| Title |
|---|
| "Remington: The Science and Practice of Pharmacy, " Lippincott Williams & Wilkins, Philadelphia, 20th edition (2003) 및 21" edition (2005)] |
| "Remington's Pharmaceutical Sciences, "Mack Pub. Co., New Jersey (1991) |
| B. Lygo and N. O’Conner (1990), Epoxide Ring Opening by Dianions Derived from β-Ketosulphones. Synthetic Studies on the 7-Hydroxy-4-oxopropenoate System and Medium-Ring Lactones, Synlett: 282-284] |
| D.C. Aldridge and J.F. Grove, (1964), Metabolic Products of Stemphylium radicinum. Part II.(-)-7-Hydroxy-4-oxo-oct-2-enoic Acid Lactone, Journal of the Chemical Society: 3239-3241] |
| J.F. Grove (1964), Metabolic Products of Stemphylium radicinum. Part I. Radicinin., Journal of the Chemical Society: 3234-3239] |
| Lee, "Diffusion-Controlled Matrix Systems", pp. 155-198 |
| Prescott, Ed., Methods in Cell Biology, Volume XIV, Academic Press, New York, N.Y., p. 33 et seq (1976) |
| Ron and Langer, "Erodible Systems", pp. 199-224, in "Treatise on Controlled Drug Delivery", A. Kydonieus Ed. , Marcel Dekker, Inc. , New York 1992] |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2016018153A1 (en) | 2016-02-04 |
| JP2017528425A (ja) | 2017-09-28 |
| US9920025B2 (en) | 2018-03-20 |
| US20170210722A1 (en) | 2017-07-27 |
| EP3174867B1 (en) | 2019-11-27 |
| EP3174867A1 (en) | 2017-06-07 |
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| PA0105 | International application |
Patent event date: 20170125 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PC1203 | Withdrawal of no request for examination |