KR20170010019A - 방사선 및 화학적 손상으로부터 보호하기 위한 세코이솔라리시레시놀 디글루코사이드(ｓｄｇ) 및 관련 화합물의 용도 - Google Patents

방사선 및 화학적 손상으로부터 보호하기 위한 세코이솔라리시레시놀 디글루코사이드(ｓｄｇ) 및 관련 화합물의 용도 Download PDF

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KR20170010019A
KR20170010019A KR1020167037042A KR20167037042A KR20170010019A KR 20170010019 A KR20170010019 A KR 20170010019A KR 1020167037042 A KR1020167037042 A KR 1020167037042A KR 20167037042 A KR20167037042 A KR 20167037042A KR 20170010019 A KR20170010019 A KR 20170010019A
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South Korea
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sdg
exposed
subject
radiation
cells
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English (en)
Korean (ko)
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멜포 크리스토피도-솔로미도
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더 트러스티스 오브 더 유니버시티 오브 펜실베니아
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Publication of KR20170010019A publication Critical patent/KR20170010019A/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
KR1020167037042A 2014-05-30 2015-06-01 방사선 및 화학적 손상으로부터 보호하기 위한 세코이솔라리시레시놀 디글루코사이드(ｓｄｇ) 및 관련 화합물의 용도 Withdrawn KR20170010019A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462005330P 2014-05-30 2014-05-30
US62/005,330 2014-05-30
US201562101296P 2015-01-08 2015-01-08
US62/101,296 2015-01-08
PCT/US2015/033501 WO2015184441A2 (en) 2014-05-30 2015-06-01 USE OF SECOISOLARICIRESINOL DIGLUCOSIDES (SDGs) AND RELATED COMPOUNDS FOR PROTECTION AGAINST RADIATION AND CHEMICAL DAMAGE

Publications (1)

Publication Number Publication Date
KR20170010019A true KR20170010019A (ko) 2017-01-25

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167037042A Withdrawn KR20170010019A (ko) 2014-05-30 2015-06-01 방사선 및 화학적 손상으로부터 보호하기 위한 세코이솔라리시레시놀 디글루코사이드(ｓｄｇ) 및 관련 화합물의 용도

Country Status (9)

Country Link
EP (1) EP3148560A4 (enExample)
JP (2) JP2017520620A (enExample)
KR (1) KR20170010019A (enExample)
CN (2) CN112336736A (enExample)
AU (2) AU2015266614A1 (enExample)
CA (1) CA2950744A1 (enExample)
IL (1) IL249219A0 (enExample)
MA (1) MA39899A (enExample)
WO (1) WO2015184441A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017214039A1 (en) * 2016-06-07 2017-12-14 University Of Pennsylvania Compositions and methods for protecting organs from ischemia/reperfusion injury associated with transplantation
WO2018187272A1 (en) * 2017-04-03 2018-10-11 Gusto Global, Llc Rational design of microbial-based biotherapeutics
CA3077034A1 (en) * 2017-09-27 2019-04-04 The Trustees Of The University Of Pennsylvania Use of secoisolariciresinol diglucosides (sdgs) and related compounds for protection against radiation-induced cardiovascular dysfunction
US20210128596A1 (en) * 2017-09-27 2021-05-06 University Of Pennsylvania Compositions and methods for treating septic cardiomyopathy
EP3843557B1 (en) * 2018-08-31 2023-09-20 Innophos, LLC An extract of anacardium occidentale for use in treating oxidation induced dna damage
CN116850162A (zh) * 2023-08-08 2023-10-10 南通大学附属医院 肠二醇在制备治疗放射性肠炎药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486126B1 (en) * 1999-06-30 2002-11-26 University Of Saskatchewan Technologies Incorporated Antioxidant activity in SDG metabolites
CA2416796A1 (en) * 2000-06-14 2001-12-20 Alla Shapiro Radioprotective agents
CN100365005C (zh) * 2006-03-02 2008-01-30 江南大学 一种从亚麻籽中提取纯化开环异落叶松树脂酚二葡萄糖苷的方法
US20070293458A1 (en) * 2006-06-16 2007-12-20 Ip-6 Research Inc. Prevention of nuclear, solar, and other radiation-induced tissue damage
US10449224B2 (en) * 2007-05-25 2019-10-22 The Trustees Of The University Of Pennsylvania Flaxseed lignan complex, methods of using and compositions thereof
WO2010017332A2 (en) * 2008-08-07 2010-02-11 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health & Human Services Radioprotectants targeting thrombospondin-1 and cd47
CN101759731B (zh) * 2008-12-25 2011-10-19 中国科学院兰州化学物理研究所 亚麻籽胶和开环异落叶松树脂酚二葡萄糖苷的提取方法
TR201815423T4 (tr) * 2013-06-10 2018-11-21 Scripps Research Inst (s,s)-sekoi̇zolari̇si̇resi̇nol di̇glukozi̇d ve (r,r)-sekoi̇zolari̇si̇resi̇nol di̇glukozi̇d'i̇n hazirlanmasi.

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Publication number Publication date
AU2020270469A1 (en) 2020-12-17
AU2015266614A1 (en) 2016-12-15
JP2017520620A (ja) 2017-07-27
EP3148560A4 (en) 2018-04-25
CN112336736A (zh) 2021-02-09
MA39899A (fr) 2021-05-26
IL249219A0 (en) 2017-02-28
EP3148560A2 (en) 2017-04-05
JP2020121987A (ja) 2020-08-13
CN107155304A (zh) 2017-09-12
WO2015184441A2 (en) 2015-12-03
WO2015184441A9 (en) 2016-01-21
CA2950744A1 (en) 2015-12-03
WO2015184441A3 (en) 2016-03-10

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PA0105 International application

Patent event date: 20161230

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination