KR20160105979A - 인슐린-아연 복합체의 제조 방법 - Google Patents
인슐린-아연 복합체의 제조 방법 Download PDFInfo
- Publication number
- KR20160105979A KR20160105979A KR1020167023293A KR20167023293A KR20160105979A KR 20160105979 A KR20160105979 A KR 20160105979A KR 1020167023293 A KR1020167023293 A KR 1020167023293A KR 20167023293 A KR20167023293 A KR 20167023293A KR 20160105979 A KR20160105979 A KR 20160105979A
- Authority
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- South Korea
- Prior art keywords
- insulin
- cooh
- chain
- group
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000000034 method Methods 0.000 title claims abstract description 79
- 238000002360 preparation method Methods 0.000 title claims description 11
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Landscapes
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
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| US33349710P | 2010-05-11 | 2010-05-11 | |
| US61/333,497 | 2010-05-11 | ||
| PCT/EP2011/057388 WO2011141407A1 (en) | 2010-05-10 | 2011-05-09 | Process for the preparation of insulin-zinc complexes |
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| KR20160105979A true KR20160105979A (ko) | 2016-09-08 |
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| MX (1) | MX2012012943A (enExample) |
| RU (1) | RU2572214C2 (enExample) |
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Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8067362B2 (en) | 2005-02-02 | 2011-11-29 | Novo Nordisk As | Insulin derivatives |
| PT1969004E (pt) | 2005-12-28 | 2011-11-25 | Novo Nordisk As | Composições que compreendem uma insulina acilada e zinco e método para criar tais composições |
| WO2007096431A1 (en) | 2006-02-27 | 2007-08-30 | Novo Nordisk A/S | Insulin derivatives |
| EP2386572B1 (en) | 2006-05-09 | 2015-07-08 | Novo Nordisk A/S | Insulin derivative |
| US8796205B2 (en) | 2006-05-09 | 2014-08-05 | Novo Nordisk A/S | Insulin derivative |
| JP5552046B2 (ja) | 2007-06-13 | 2014-07-16 | ノボ・ノルデイスク・エー／エス | インスリン誘導体を含有する薬学的製剤 |
| EP2217621B1 (en) | 2007-11-08 | 2015-04-22 | Novo Nordisk A/S | Insulin derivative |
| KR20110085985A (ko) | 2008-10-30 | 2011-07-27 | 노보 노르디스크 에이/에스 | 하루 한번 주사 빈도보다 적은 인슐린 주사를 사용한 진성 당뇨병의 치료 |
| JP6049625B2 (ja) | 2010-10-27 | 2016-12-21 | ノヴォ ノルディスク アー／エス | 様々な注射間隔を用いて施されるインスリン注射を使用する、真性糖尿病の治療 |
| JP6755175B2 (ja) * | 2013-03-20 | 2020-09-16 | ノヴォ ノルディスク アー／エス | インスリン投薬レジメン |
| WO2014177623A1 (en) | 2013-04-30 | 2014-11-06 | Novo Nordisk A/S | Novel administration regime |
| WO2015052088A1 (en) * | 2013-10-07 | 2015-04-16 | Novo Nordisk A/S | Novel derivative of an insulin analogue |
| AR099569A1 (es) | 2014-02-28 | 2016-08-03 | Novo Nordisk As | Derivados de insulina y los usos médicos de estos |
| DK3006045T3 (en) | 2014-10-07 | 2017-07-17 | Cyprumed Gmbh | Pharmaceutical formulations for oral administration of peptide or protein drugs |
| MX2020005916A (es) | 2017-12-07 | 2020-10-19 | Adocia | Composiciones en forma de una solución acuosa inyectable que comprende amilina, un receptor agonista de amilina o un análogo de amilina y un copoliaminoácido. |
| WO2019110797A1 (fr) * | 2017-12-07 | 2019-06-13 | Adocia | Compositions sous forme d'une solution aqueuse injectable comprenant de l'amyline, un agoniste au recepteur de l'amyline ou un analogue d'amyline et un co-polyaminoacide |
| CA3090199A1 (en) * | 2018-02-01 | 2019-08-08 | Jiangsu Hengrui Medicine Co., Ltd. | Pharmaceutical composition comprising acylated derivative of human insulin analog and preparation method thereof |
| CA3100869A1 (en) | 2018-05-24 | 2019-11-28 | Jiangsu Hengrui Medicine Co., Ltd. | Method for preparing precursor of recombinant human insulin or analogue thereof |
| US10335464B1 (en) | 2018-06-26 | 2019-07-02 | Novo Nordisk A/S | Device for titrating basal insulin |
| SG11202106167XA (en) | 2018-12-11 | 2021-07-29 | Sanofi Sa | Insulin conjugates |
| EP3996679B1 (en) | 2019-07-12 | 2023-09-06 | Novo Nordisk A/S | High concentration insulin formulation |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1212679B (de) * | 1957-08-03 | 1966-03-17 | Novo Terapeutisk Labor As | Verfahren zur Herstellung von Insulinloesungen |
| GB1042194A (en) * | 1962-04-30 | 1966-09-14 | Olin Mathieson | Insulin preparations |
| US3868358A (en) * | 1971-04-30 | 1975-02-25 | Lilly Co Eli | Protamine-insulin product |
| DK113585D0 (da) * | 1985-03-12 | 1985-03-12 | Novo Industri As | Nye peptider |
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| US4764592A (en) * | 1987-04-23 | 1988-08-16 | Eli Lilly And Company | Crystalline human proinsulin and process for its production |
| FI913037A0 (fi) | 1988-12-23 | 1991-06-20 | Novo Nordisk As | Humana insulinanaloger. |
| PT93057B (pt) | 1989-02-09 | 1995-12-29 | Lilly Co Eli | Processo para a preparacao de analogos da insulina |
| EP1132404A3 (en) * | 1993-09-17 | 2002-03-27 | Novo Nordisk A/S | Acylated insulin |
| US7097845B2 (en) * | 1997-04-23 | 2006-08-29 | Jacob Sten Petersen | Combinations of antigen and mucosal binding component for inducing specific immunological tolerance |
| EP2107069B1 (en) | 2003-08-05 | 2013-01-16 | Novo Nordisk A/S | Novel insulin derivatives |
| ES2402592T3 (es) * | 2003-08-05 | 2013-05-07 | Novo Nordisk A/S | Nuevos derivados de insulina |
| PT1969004E (pt) | 2005-12-28 | 2011-11-25 | Novo Nordisk As | Composições que compreendem uma insulina acilada e zinco e método para criar tais composições |
| JP5552046B2 (ja) * | 2007-06-13 | 2014-07-16 | ノボ・ノルデイスク・エー／エス | インスリン誘導体を含有する薬学的製剤 |
| TWI451876B (zh) * | 2008-06-13 | 2014-09-11 | Lilly Co Eli | 聚乙二醇化之離脯胰島素化合物 |
-
2011
- 2011-05-09 KR KR1020167023293A patent/KR20160105979A/ko not_active Ceased
- 2011-05-09 WO PCT/EP2011/057388 patent/WO2011141407A1/en not_active Ceased
- 2011-05-09 MX MX2012012943A patent/MX2012012943A/es active IP Right Grant
- 2011-05-09 RU RU2012148821/15A patent/RU2572214C2/ru not_active IP Right Cessation
- 2011-05-09 ES ES11718398.8T patent/ES2612468T3/es active Active
- 2011-05-09 KR KR1020127029547A patent/KR20130092972A/ko not_active Ceased
- 2011-05-09 JP JP2013509525A patent/JP6249773B2/ja active Active
- 2011-05-09 CN CN201611166272.4A patent/CN107029212A/zh active Pending
- 2011-05-09 CN CN201180023303XA patent/CN102883743A/zh active Pending
- 2011-05-09 CA CA2795091A patent/CA2795091A1/en not_active Withdrawn
- 2011-05-09 US US13/696,897 patent/US20130143803A1/en not_active Abandoned
- 2011-05-09 AU AU2011252127A patent/AU2011252127B2/en not_active Ceased
- 2011-05-09 EP EP11718398.8A patent/EP2569002B1/en active Active
- 2011-05-09 BR BR112012028766A patent/BR112012028766A2/pt not_active Application Discontinuation
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2015
- 2015-03-19 US US14/662,874 patent/US20150250857A1/en not_active Abandoned
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2017
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- 2017-08-16 JP JP2017157054A patent/JP2017203042A/ja not_active Withdrawn
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2020
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Also Published As
| Publication number | Publication date |
|---|---|
| MX2012012943A (es) | 2012-11-29 |
| CN107029212A (zh) | 2017-08-11 |
| US20150250857A1 (en) | 2015-09-10 |
| US20130143803A1 (en) | 2013-06-06 |
| US20170165327A1 (en) | 2017-06-15 |
| KR20130092972A (ko) | 2013-08-21 |
| CN102883743A (zh) | 2013-01-16 |
| AU2011252127A1 (en) | 2012-11-01 |
| JP2017203042A (ja) | 2017-11-16 |
| EP2569002B1 (en) | 2016-10-26 |
| RU2572214C2 (ru) | 2015-12-27 |
| ES2612468T3 (es) | 2017-05-17 |
| RU2012148821A (ru) | 2014-06-20 |
| JP2013526501A (ja) | 2013-06-24 |
| BR112012028766A2 (pt) | 2017-06-13 |
| AU2011252127B2 (en) | 2014-02-20 |
| CA2795091A1 (en) | 2011-11-17 |
| US20240307503A1 (en) | 2024-09-19 |
| WO2011141407A1 (en) | 2011-11-17 |
| US20210060132A1 (en) | 2021-03-04 |
| JP6249773B2 (ja) | 2017-12-20 |
| EP2569002A1 (en) | 2013-03-20 |
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