KR20160078956A - 취약 x 증후군 및 관련 장애의 치료 방법 - Google Patents

취약 x 증후군 및 관련 장애의 치료 방법 Download PDF

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Publication number
KR20160078956A
KR20160078956A KR1020167009040A KR20167009040A KR20160078956A KR 20160078956 A KR20160078956 A KR 20160078956A KR 1020167009040 A KR1020167009040 A KR 1020167009040A KR 20167009040 A KR20167009040 A KR 20167009040A KR 20160078956 A KR20160078956 A KR 20160078956A
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South Korea
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mice
metadoxine
fmr1
metadoxin
treatment
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KR1020167009040A
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English (en)
Korean (ko)
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야론 다니엘리
달리아 메지도
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알코브라 리미티드
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Priority claimed from US14/038,258 external-priority patent/US20150073023A1/en
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Publication of KR20160078956A publication Critical patent/KR20160078956A/ko
Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415Pyridoxine, i.e. Vitamin B6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
KR1020167009040A 2013-09-09 2014-09-09 취약 x 증후군 및 관련 장애의 치료 방법 Withdrawn KR20160078956A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361875384P 2013-09-09 2013-09-09
US61/875,384 2013-09-09
US14/038,258 2013-09-26
US14/038,258 US20150073023A1 (en) 2013-09-09 2013-09-26 Method Of Treating Fragile X Syndrome And Related Disorders
US201461991351P 2014-05-09 2014-05-09
US61/991,351 2014-05-09
PCT/IB2014/002398 WO2015033224A2 (en) 2013-09-09 2014-09-09 Methods of treating fragile x syndrome and related disorders

Publications (1)

Publication Number Publication Date
KR20160078956A true KR20160078956A (ko) 2016-07-05

Family

ID=52629036

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020167009040A Withdrawn KR20160078956A (ko) 2013-09-09 2014-09-09 취약 x 증후군 및 관련 장애의 치료 방법
KR1020167009042A Withdrawn KR20160086818A (ko) 2013-09-09 2014-09-09 요법에 대한 반응의 결정 방법

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020167009042A Withdrawn KR20160086818A (ko) 2013-09-09 2014-09-09 요법에 대한 반응의 결정 방법

Country Status (12)

Country Link
EP (2) EP3044589A1 (cg-RX-API-DMAC7.html)
JP (2) JP2016530291A (cg-RX-API-DMAC7.html)
KR (2) KR20160078956A (cg-RX-API-DMAC7.html)
CN (2) CN105917225A (cg-RX-API-DMAC7.html)
AU (2) AU2014316779A1 (cg-RX-API-DMAC7.html)
CA (2) CA2923421A1 (cg-RX-API-DMAC7.html)
EA (2) EA201690559A1 (cg-RX-API-DMAC7.html)
IL (2) IL244343A0 (cg-RX-API-DMAC7.html)
MX (2) MX2016003006A (cg-RX-API-DMAC7.html)
SG (2) SG11201601830PA (cg-RX-API-DMAC7.html)
TW (2) TW201606304A (cg-RX-API-DMAC7.html)
WO (2) WO2015033224A2 (cg-RX-API-DMAC7.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019203509A1 (ko) * 2018-04-18 2019-10-24 건국대학교 글로컬산학협력단 아그마틴 및 이의 약학적으로 허용 가능한 염을 포함하는 취약 x 증후군 예방 또는 치료용 약학조성물
WO2021141426A1 (ko) * 2020-01-08 2021-07-15 건국대학교 글로컬산학협력단 리수리드 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물
WO2021158059A1 (ko) * 2020-02-07 2021-08-12 건국대학교 글로컬산학협력단 릴메니딘 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3239161A1 (en) * 2013-07-31 2017-11-01 UDC Ireland Limited Luminescent diazabenzimidazole carbene metal complexes
US20150073023A1 (en) 2013-09-09 2015-03-12 Alcobra Ltd. Method Of Treating Fragile X Syndrome And Related Disorders
CN108538365A (zh) * 2017-03-24 2018-09-14 华东师范大学 一种基于数据分析技术的自闭症社交能力评估系统
CN112055587A (zh) * 2018-04-13 2020-12-08 Healx有限公司 脆性x综合征的治疗
JP7387179B2 (ja) * 2018-06-07 2023-11-28 オービッド・セラピューティクス・インコーポレイテッド 発達障害の処置における(s)-3-アミノ-4-(ジフルオロメチレニル)シクロペンタ-1-エン-1-カルボン酸および関連化合物、(1s,3s)-3-アミノ-4-(ジフルオロメチリデン)シクロペンタン-1-カルボン酸ならびにビガバトリンの使用
CA3183065A1 (en) * 2020-06-29 2022-01-06 James GRIESSER Treatment of fragile x syndrome with cannabidiol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1131856B (it) 1980-06-30 1986-06-25 Baldacci Lab Spa Composizione farmaceutica per il trattamento di intossicazioni alcooliche
US20020155170A1 (en) * 2000-11-30 2002-10-24 Walsh William John Nutrient supplements and methods for treating autism and for preventing the onset of autism
IL187159A0 (en) 2007-07-03 2009-02-11 Gur Megiddo Use of metadoxine in relief of alcohol intoxication
BRPI1015231A2 (pt) * 2009-06-25 2018-02-20 Alcobra Ltd método para tratamento, suavização de sintomas, alívio, melhoria e prevenção de uma doença, distúrbio ou condição cognitiva

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019203509A1 (ko) * 2018-04-18 2019-10-24 건국대학교 글로컬산학협력단 아그마틴 및 이의 약학적으로 허용 가능한 염을 포함하는 취약 x 증후군 예방 또는 치료용 약학조성물
WO2021141426A1 (ko) * 2020-01-08 2021-07-15 건국대학교 글로컬산학협력단 리수리드 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물
WO2021158059A1 (ko) * 2020-02-07 2021-08-12 건국대학교 글로컬산학협력단 릴메니딘 화합물을 유효성분으로 포함하는 취약 x 증후군 또는 관련 발달 장애 치료용 조성물
US12396983B2 (en) 2020-02-07 2025-08-26 Neuroventi Composition comprising rilmenidine compound as active ingredient for treatment of fragile X syndrome or related developmental disability

Also Published As

Publication number Publication date
TW201606304A (zh) 2016-02-16
IL244453A0 (en) 2016-04-21
AU2014316779A1 (en) 2016-03-17
SG11201601605YA (en) 2016-04-28
CN105517546A (zh) 2016-04-20
JP2016530536A (ja) 2016-09-29
IL244343A0 (en) 2016-04-21
EP3043792A2 (en) 2016-07-20
JP2016530291A (ja) 2016-09-29
MX2016003002A (es) 2016-09-08
TW201605443A (zh) 2016-02-16
CN105917225A (zh) 2016-08-31
WO2015033224A3 (en) 2015-07-02
WO2015035402A1 (en) 2015-03-12
MX2016003006A (es) 2016-06-10
AU2014315026A1 (en) 2016-03-24
CA2922901A1 (en) 2015-03-12
EP3044589A1 (en) 2016-07-20
WO2015033224A2 (en) 2015-03-12
KR20160086818A (ko) 2016-07-20
EA201690557A1 (ru) 2016-07-29
SG11201601830PA (en) 2016-04-28
EA201690559A1 (ru) 2016-08-31
CA2923421A1 (en) 2015-03-12

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Date Code Title Description
PA0105 International application

Patent event date: 20160406

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid