KR20160029128A - 이중특이적 cd3 및 cd19 항원 결합 구조체 - Google Patents

이중특이적 cd3 및 cd19 항원 결합 구조체 Download PDF

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KR20160029128A
KR20160029128A KR1020167003567A KR20167003567A KR20160029128A KR 20160029128 A KR20160029128 A KR 20160029128A KR 1020167003567 A KR1020167003567 A KR 1020167003567A KR 20167003567 A KR20167003567 A KR 20167003567A KR 20160029128 A KR20160029128 A KR 20160029128A
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antigen
binding
cell
construct
cells
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고든 유곤 엔지
서짓 비마라오 디지트
토마스 스프레터 폰 그루덴스타인
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자임워크스 인코포레이티드
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    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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KR1020167003567A 2013-07-12 2014-07-11 이중특이적 cd3 및 cd19 항원 결합 구조체 Withdrawn KR20160029128A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361845948P 2013-07-12 2013-07-12
US61/845,948 2013-07-12
US201461927877P 2014-01-15 2014-01-15
US61/927,877 2014-01-15
US201461978719P 2014-04-11 2014-04-11
US61/978,719 2014-04-11
PCT/US2014/046436 WO2015006749A2 (en) 2013-07-12 2014-07-11 Bispecific cd3 and cd19 antigen binding contructs

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Publication Number Publication Date
KR20160029128A true KR20160029128A (ko) 2016-03-14

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KR1020167003567A Withdrawn KR20160029128A (ko) 2013-07-12 2014-07-11 이중특이적 cd3 및 cd19 항원 결합 구조체

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US (1) US20160355588A1 (https=)
EP (1) EP3019622A4 (https=)
JP (1) JP2016531100A (https=)
KR (1) KR20160029128A (https=)
CN (1) CN105531374A (https=)
AU (1) AU2014287011A1 (https=)
BR (1) BR112016000666A2 (https=)
CA (1) CA2917886A1 (https=)
MX (1) MX2016000272A (https=)
RU (1) RU2016104130A (https=)
WO (1) WO2015006749A2 (https=)

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CA2854233C (en) 2011-11-04 2020-05-12 Zymeworks Inc. Stable heterodimeric antibody design with mutations in the fc domain
EP2892924B1 (en) * 2012-06-14 2020-11-25 Therapix Biosciences Ltd. Humanized antibodies to cluster of differentiation 3 (cd3)
WO2014004586A1 (en) 2012-06-25 2014-01-03 Zymeworks Inc. Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells
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JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
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MX373245B (es) * 2013-07-05 2020-05-11 Genmab As Anticuerpos cd3 humanizados o quiméricos.
UA129760C2 (uk) 2013-12-17 2025-07-30 Дженентек, Інк. Анти-cd3 антитіло та спосіб його застосування
US20160326249A1 (en) * 2014-01-15 2016-11-10 Zymeworks Inc. Bi-specific cd3 and cd19 antigen-binding constructs
CN106459990B (zh) 2014-02-07 2021-06-01 麦克马斯特大学 三功能t细胞抗原偶联物及其制备方法和用途
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KR20170066421A (ko) 2014-09-12 2017-06-14 제넨테크, 인크. 항-cll-1 항체 및 면역접합체
RS60739B1 (sr) 2014-11-17 2020-09-30 Regeneron Pharma Postupci za lečenje tumora upotrebom cd3xcd20 bispecifičnog antitela
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