KR20150127249A - 암 치료를 위한 암 줄기세포 경로 키나아제의 저해제로서 3-(아릴 또는 헤테로아릴)메틸렌인돌린-2-온 유도체 - Google Patents

암 치료를 위한 암 줄기세포 경로 키나아제의 저해제로서 3-(아릴 또는 헤테로아릴)메틸렌인돌린-2-온 유도체 Download PDF

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KR20150127249A
KR20150127249A KR1020157028817A KR20157028817A KR20150127249A KR 20150127249 A KR20150127249 A KR 20150127249A KR 1020157028817 A KR1020157028817 A KR 1020157028817A KR 20157028817 A KR20157028817 A KR 20157028817A KR 20150127249 A KR20150127249 A KR 20150127249A
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substituted
heterocycle
alkyl
compound
aryl
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치앙 제이 리
지-펭 리우
웨이 리
아만다 지보
해리 로고프
가츠노리 츠보이
유스케 다카나시
신고 도조
도모히로 고다마
가츠미 구보타
도시오 가나이
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보스톤 바이오메디칼, 인크.
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KR1020157028817A 2013-03-13 2014-03-13 암 치료를 위한 암 줄기세포 경로 키나아제의 저해제로서 3-(아릴 또는 헤테로아릴)메틸렌인돌린-2-온 유도체 Ceased KR20150127249A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361780248P 2013-03-13 2013-03-13
US201361780263P 2013-03-13 2013-03-13
US61/780,248 2013-03-13
US61/780,263 2013-03-13
PCT/US2014/026498 WO2014160401A1 (en) 2013-03-13 2014-03-13 3-(aryl or heteroaryl) methyleneindolin-2-one derivatives as inhibitors of cancer stem cell pathway kinases for the treatment of cancer

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US (2) US20160031888A1 (enExample)
EP (1) EP2970206A1 (enExample)
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CN (1) CN105408320B (enExample)
AU (2) AU2014243869A1 (enExample)
BR (1) BR112015022431A2 (enExample)
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EP4157858A4 (en) * 2020-05-29 2024-08-28 The Regents of The University of Michigan Small molecule inhibitors of grk5 and grk5 subfamily members and uses thereof
CN111675647B (zh) * 2020-06-26 2022-03-01 深圳技术大学 2-吲哚酮类pak1抑制剂及其在抗肿瘤治疗药物中的应用
CN116171279B9 (zh) * 2020-07-10 2026-05-12 荣山医药股份有限公司 大环化合物及其用途
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JP6378308B2 (ja) 2018-08-22
RU2019104092A (ru) 2019-03-20
AU2018233033A1 (en) 2018-10-11
WO2014160401A1 (en) 2014-10-02
SG11201507346PA (en) 2015-10-29
EP2970206A1 (en) 2016-01-20
CN105408320A (zh) 2016-03-16
RU2015143526A (ru) 2017-04-19
HK1220184A1 (zh) 2017-04-28
US20160031888A1 (en) 2016-02-04
SG10201806965XA (en) 2018-09-27
US20190241569A1 (en) 2019-08-08
JP2016513656A (ja) 2016-05-16
CA2904152A1 (en) 2014-10-02
JP2018168187A (ja) 2018-11-01
BR112015022431A2 (pt) 2017-05-09
AU2014243869A1 (en) 2015-09-24

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