KR20140113921A - 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법 - Google Patents

20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법 Download PDF

Info

Publication number
KR20140113921A
KR20140113921A KR1020147017339A KR20147017339A KR20140113921A KR 20140113921 A KR20140113921 A KR 20140113921A KR 1020147017339 A KR1020147017339 A KR 1020147017339A KR 20147017339 A KR20147017339 A KR 20147017339A KR 20140113921 A KR20140113921 A KR 20140113921A
Authority
KR
South Korea
Prior art keywords
fatty acid
carbon
eta
dgla
gla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020147017339A
Other languages
English (en)
Korean (ko)
Inventor
메하르 만쿠
조나단 로우
Original Assignee
디그너티 사이언스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 디그너티 사이언스 리미티드 filed Critical 디그너티 사이언스 리미티드
Publication of KR20140113921A publication Critical patent/KR20140113921A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/005—Splitting up mixtures of fatty acids into their constituents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/007—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids using organic solvents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/025—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by saponification and release of fatty acids
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08—Refining
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6431—Linoleic acids [18:2[n-6]]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
KR1020147017339A 2011-11-29 2012-11-29 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법 Withdrawn KR20140113921A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161564652P 2011-11-29 2011-11-29
US61/564,652 2011-11-29
US201261711585P 2012-10-09 2012-10-09
US61/711,585 2012-10-09
PCT/US2012/067030 WO2013082265A1 (en) 2011-11-29 2012-11-29 Compositions comprising 20-carbon fatty acids and methods of making and using same

Publications (1)

Publication Number Publication Date
KR20140113921A true KR20140113921A (ko) 2014-09-25

Family

ID=48536046

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147017339A Withdrawn KR20140113921A (ko) 2011-11-29 2012-11-29 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법

Country Status (15)

Country Link
US (1) US9096815B2 (https=)
EP (1) EP2785852A4 (https=)
JP (1) JP2015500639A (https=)
KR (1) KR20140113921A (https=)
CN (1) CN104114709A (https=)
AU (1) AU2012345942A1 (https=)
BR (1) BR112014013098A2 (https=)
CA (1) CA2856715A1 (https=)
IL (1) IL232748A0 (https=)
MX (1) MX2014006478A (https=)
PH (1) PH12014501212A1 (https=)
RU (1) RU2014126356A (https=)
SG (1) SG11201402653QA (https=)
WO (1) WO2013082265A1 (https=)
ZA (1) ZA201403784B (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
JP2015500639A (ja) 2011-11-29 2015-01-08 ディグニティ サイエンシス リミテッド ２０−炭素脂肪酸を含む組成物ならびにその製造方法および使用方法
GB201301626D0 (en) 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
JP2016538288A (ja) 2013-11-15 2016-12-08 ディグニティ サイエンシス リミテッド 多価不飽和ヒドロキシ脂肪酸の薬学的に許容される塩
EP3733857A3 (en) 2013-12-04 2020-12-09 Nippon Suisan Kaisha, Ltd. Dihomo-gamma-linolenic acid-containing microbial oil and dihomo-gamma-linolenic acid-containing microbial biomass
US9682055B2 (en) 2014-06-04 2017-06-20 Dignity Sciences Limted Pharmaceutical compositions comprising DGLA and use of same
MA41120A (fr) 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci
ES2851525T3 (es) 2015-07-21 2021-09-07 Afimmune Ltd Composiciones que comprenden 15(S)-HEPE para su uso en la sensibilización de las células cancerosas a la radioterapia
EP3345986A4 (en) * 2015-08-31 2019-05-01 Nippon Suisan Kaisha, Ltd. COMPOSITION WITH FREE MULTIPLE UNSATURATED FATTY ACIDS AND MANUFACTURING METHOD THEREFOR
CA3129008A1 (en) 2015-12-18 2017-06-22 Afimmune Limited Compositions comprising 15-hepe and methods of using the same
CN105535064A (zh) * 2016-01-19 2016-05-04 佛山科学技术学院 一种琉璃苣深加工方法及其深加工产物
CN109796328B (zh) * 2019-03-14 2022-03-25 浙江工业大学 一种高纯度香榧籽油金松酸的分离方法
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
CN113004977A (zh) * 2021-02-25 2021-06-22 华侨大学 高纯度多不饱和鱼油的制备方法以及鱿鱼油加工方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH663951A5 (fr) * 1984-10-10 1988-01-29 Nestle Sa Procede d'enrichissement selectif en acides gras polyinsatures d'un melange contenant des acides gras fractions enrichies obtenues et compositions les contenant.
CH669208A5 (fr) * 1986-12-17 1989-02-28 Nestle Sa Procede de fractionnement en continu d'un melange d'acides gras.
NZ337459A (en) * 1997-04-11 2000-07-28 Abbott Lab Nucleic acid construct in plants and dietary supplement
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
JP3425622B2 (ja) * 2000-03-30 2003-07-14 独立行政法人産業技術総合研究所 ラビリンチュラ属菌を用いた高度不飽和脂肪酸含有培養物および高度不飽和脂肪酸含有油脂の製造方法
AU2004290051A1 (en) * 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
DK1756280T3 (en) 2004-04-22 2015-02-02 Commw Scient Ind Res Org SYNTHESIS OF CHAIN, polyunsaturated fatty acids BY RECOMBINANT CELLS
CA2649337C (en) * 2006-04-13 2014-11-18 Nippon Suisan Kaisha, Ltd. Process for preparing concentrated polyunsaturated fatty acid oil
US20080125487A1 (en) * 2006-11-17 2008-05-29 Tapas Das Elongase gene and uses thereof
US20080213357A1 (en) * 2007-02-12 2008-09-04 Andrew Bruce Hebard Plant Derived Lipid Useful for Nutraceutical and Cosemeceutical Applications
WO2009130291A2 (de) 2008-04-25 2009-10-29 Basf Plant Science Gmbh Pflanzensamenöl
US8188335B2 (en) * 2009-07-17 2012-05-29 Abbott Laboratories Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
JP2015500639A (ja) 2011-11-29 2015-01-08 ディグニティ サイエンシス リミテッド ２０−炭素脂肪酸を含む組成物ならびにその製造方法および使用方法

Also Published As

Publication number Publication date
CN104114709A (zh) 2014-10-22
US9096815B2 (en) 2015-08-04
RU2014126356A (ru) 2016-01-27
CA2856715A1 (en) 2013-06-06
BR112014013098A2 (pt) 2017-06-13
EP2785852A4 (en) 2015-11-04
JP2015500639A (ja) 2015-01-08
WO2013082265A1 (en) 2013-06-06
PH12014501212A1 (en) 2014-09-08
SG11201402653QA (en) 2014-06-27
AU2012345942A1 (en) 2014-06-12
ZA201403784B (en) 2015-09-30
EP2785852A1 (en) 2014-10-08
IL232748A0 (en) 2014-07-31
US20130331448A1 (en) 2013-12-12
MX2014006478A (es) 2015-02-12

Similar Documents

Publication Publication Date Title
KR20140113921A (ko) 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법
EP1211304B1 (en) Method for isolating high-purified unsaturated fatty acids using crystallization
JP2657056B2 (ja) γ‐リノレン酸の豊富化方法
JP7190013B2 (ja) エイコサペンタエン酸アルキルエステルを含有する組成物及びその製造方法
US9546125B2 (en) Continuous process for extraction of unsaturated triglycerides from fish oil
JP2015500639A5 (https=)
US5130449A (en) Isolation of stearidonic acid from fatty acid mixtures
JP6423436B2 (ja) ポリ不飽和脂肪酸を製造するためのクロマトグラフィ方法
US20150203789A1 (en) Process for purification of epa (eicosapentanoic acid) ethyl ester from fish oil
JPH0159318B2 (https=)
JP2013545857A (ja) オメガ３濃縮物
JP6467426B2 (ja) クロマトグラフィ法による脂肪酸の精製
JP6581090B2 (ja) 脂肪酸のクロマトグラフィ精製のための方法
JPS6163624A (ja) エイコサペンタエン酸含量の高い糖脂質の製造法
CN107162910B (zh) 从鱼油中制备高纯度epa-ee的方法
EP0300844B1 (fr) Nouveaux glycérides d'acide gras insaturé et leurs procédés d'obtention
CN107922372A (zh) 从植物油馏出物回收生育酚/生育三烯酚、甘油、固醇和脂肪酸酯及其方法
CN120157575A (zh) 一种不饱和脂肪酸的制备方法
JP2014501228A (ja) 金属水素化物で多価不飽和脂肪酸を安定化するための方法
BR122024025211A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025183A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025187A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025192A2 (pt) Composição lipídica
ITMI20081200A1 (it) Procedimento di arricchimento per la preparazione di omega-3
TW201629030A (zh) 自植物油餾出物中回收生育酚／生育三烯酚、甘油、固醇和脂肪酸酯的回收程序

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20140624

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid