KR20140113921A - 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법 - Google Patents

20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법 Download PDF

Info

Publication number
KR20140113921A
KR20140113921A KR1020147017339A KR20147017339A KR20140113921A KR 20140113921 A KR20140113921 A KR 20140113921A KR 1020147017339 A KR1020147017339 A KR 1020147017339A KR 20147017339 A KR20147017339 A KR 20147017339A KR 20140113921 A KR20140113921 A KR 20140113921A
Authority
KR
South Korea
Prior art keywords
fatty acid
carbon
eta
dgla
gla
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020147017339A
Other languages
English (en)
Korean (ko)
Inventor
메하르 만쿠
조나단 로우
Original Assignee
디그너티 사이언스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 디그너티 사이언스 리미티드 filed Critical 디그너티 사이언스 리미티드
Publication of KR20140113921A publication Critical patent/KR20140113921A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/005Splitting up mixtures of fatty acids into their constituents
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/007Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids using organic solvents
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/025Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by saponification and release of fatty acids
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/08Refining
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11CFATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6431Linoleic acids [18:2[n-6]]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
KR1020147017339A 2011-11-29 2012-11-29 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법 Withdrawn KR20140113921A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161564652P 2011-11-29 2011-11-29
US61/564,652 2011-11-29
US201261711585P 2012-10-09 2012-10-09
US61/711,585 2012-10-09
PCT/US2012/067030 WO2013082265A1 (en) 2011-11-29 2012-11-29 Compositions comprising 20-carbon fatty acids and methods of making and using same

Publications (1)

Publication Number Publication Date
KR20140113921A true KR20140113921A (ko) 2014-09-25

Family

ID=48536046

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020147017339A Withdrawn KR20140113921A (ko) 2011-11-29 2012-11-29 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법

Country Status (15)

Country Link
US (1) US9096815B2 (enExample)
EP (1) EP2785852A4 (enExample)
JP (1) JP2015500639A (enExample)
KR (1) KR20140113921A (enExample)
CN (1) CN104114709A (enExample)
AU (1) AU2012345942A1 (enExample)
BR (1) BR112014013098A2 (enExample)
CA (1) CA2856715A1 (enExample)
IL (1) IL232748A0 (enExample)
MX (1) MX2014006478A (enExample)
PH (1) PH12014501212A1 (enExample)
RU (1) RU2014126356A (enExample)
SG (1) SG11201402653QA (enExample)
WO (1) WO2013082265A1 (enExample)
ZA (1) ZA201403784B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
US8293790B2 (en) 2011-10-19 2012-10-23 Dignity Sciences Limited Pharmaceutical compositions comprising DGLA and benzoyl peroxide and methods of use thereof
JP2015500639A (ja) 2011-11-29 2015-01-08 ディグニティ サイエンシス リミテッド 20−炭素脂肪酸を含む組成物ならびにその製造方法および使用方法
GB201301626D0 (en) 2013-01-30 2013-03-13 Dignity Sciences Ltd Composition comprising 15-OHEPA and methods of using the same
CN105899485B (zh) 2013-11-15 2018-10-19 尊严科学有限公司 多不饱和羟基脂肪酸的药学上可接受的盐
CN114410374B (zh) 2013-12-04 2025-01-07 株式会社日水 微生物油、微生物油的制造方法、浓缩微生物油及浓缩微生物油的制造方法
RU2714323C2 (ru) 2014-06-04 2020-02-14 ДиЭс БАЙОФАРМА ЛИМИТЕД Фармацевтические композиции, содержащие дглк, и их применение
MA41120A (fr) 2014-12-02 2017-10-10 Afimmune Ltd Compositions comprenant le 15-hepe et méthodes de traitement ou de prévention de la fibrose à l'aide de celles-ci
EP3861995A1 (en) 2015-07-21 2021-08-11 Affimune Limited Compositions comprising 15-hepe for use in treating or preventing neurologic disease
WO2017038861A1 (ja) * 2015-08-31 2017-03-09 日本水産株式会社 遊離多価不飽和脂肪酸含有組成物及びその製造方法
KR20180094516A (ko) 2015-12-18 2018-08-23 애피뮨 리미티드 15-hepe를 포함하는 조성물 및 이를 사용하는 방법
CN105535064A (zh) * 2016-01-19 2016-05-04 佛山科学技术学院 一种琉璃苣深加工方法及其深加工产物
CN109796328B (zh) * 2019-03-14 2022-03-25 浙江工业大学 一种高纯度香榧籽油金松酸的分离方法
US20210315851A1 (en) 2020-04-03 2021-10-14 Afimmune Limited Compositions comprising 15-hepe and methods of treating or preventing hematologic disorders, and/or related diseases
CN113004977A (zh) * 2021-02-25 2021-06-22 华侨大学 高纯度多不饱和鱼油的制备方法以及鱿鱼油加工方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH663951A5 (fr) * 1984-10-10 1988-01-29 Nestle Sa Procede d'enrichissement selectif en acides gras polyinsatures d'un melange contenant des acides gras fractions enrichies obtenues et compositions les contenant.
CH669208A5 (fr) * 1986-12-17 1989-02-28 Nestle Sa Procede de fractionnement en continu d'un melange d'acides gras.
HUP0001517A3 (en) * 1997-04-11 2002-04-29 Calgene Llc Davis Methods and compositions for synthesis of long chain polyunsaturated fatty acids in plants
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
JP3425622B2 (ja) * 2000-03-30 2003-07-14 独立行政法人産業技術総合研究所 ラビリンチュラ属菌を用いた高度不飽和脂肪酸含有培養物および高度不飽和脂肪酸含有油脂の製造方法
WO2005047479A2 (en) * 2003-11-12 2005-05-26 E.I. Dupont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oilseed plants and oleaginous yeast
ES2529572T3 (es) 2004-04-22 2015-02-23 Commonwealth Scientific And Industrial Research Organisation Síntesis de ácidos grasos poliinsaturados de cadena larga por células recombinantes
US9150817B2 (en) * 2006-04-13 2015-10-06 Nippon Suisan Kaisha, Ltd. Process for preparing concentrated polyunsaturated fatty acid oil
US20080125487A1 (en) 2006-11-17 2008-05-29 Tapas Das Elongase gene and uses thereof
US20080213357A1 (en) * 2007-02-12 2008-09-04 Andrew Bruce Hebard Plant Derived Lipid Useful for Nutraceutical and Cosemeceutical Applications
US8455035B2 (en) * 2008-04-25 2013-06-04 Basf Plant Science Gmbh Plant seed oil
US8188335B2 (en) * 2009-07-17 2012-05-29 Abbott Laboratories Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
JP2015500639A (ja) 2011-11-29 2015-01-08 ディグニティ サイエンシス リミテッド 20−炭素脂肪酸を含む組成物ならびにその製造方法および使用方法

Also Published As

Publication number Publication date
MX2014006478A (es) 2015-02-12
IL232748A0 (en) 2014-07-31
US20130331448A1 (en) 2013-12-12
BR112014013098A2 (pt) 2017-06-13
RU2014126356A (ru) 2016-01-27
JP2015500639A (ja) 2015-01-08
CA2856715A1 (en) 2013-06-06
US9096815B2 (en) 2015-08-04
PH12014501212A1 (en) 2014-09-08
EP2785852A1 (en) 2014-10-08
SG11201402653QA (en) 2014-06-27
AU2012345942A1 (en) 2014-06-12
CN104114709A (zh) 2014-10-22
WO2013082265A1 (en) 2013-06-06
ZA201403784B (en) 2015-09-30
EP2785852A4 (en) 2015-11-04

Similar Documents

Publication Publication Date Title
KR20140113921A (ko) 20-탄소 지방산을 포함하는 조성물 및 이를 제조 및 사용하는 방법
EP1211304B1 (en) Method for isolating high-purified unsaturated fatty acids using crystallization
JP2657056B2 (ja) γ‐リノレン酸の豊富化方法
JP7190013B2 (ja) エイコサペンタエン酸アルキルエステルを含有する組成物及びその製造方法
JP2015500639A5 (enExample)
US5130449A (en) Isolation of stearidonic acid from fatty acid mixtures
US9546125B2 (en) Continuous process for extraction of unsaturated triglycerides from fish oil
JP6423436B2 (ja) ポリ不飽和脂肪酸を製造するためのクロマトグラフィ方法
US20150203789A1 (en) Process for purification of epa (eicosapentanoic acid) ethyl ester from fish oil
JPH0159318B2 (enExample)
JP2013545857A (ja) オメガ3濃縮物
JP6467426B2 (ja) クロマトグラフィ法による脂肪酸の精製
JP6581090B2 (ja) 脂肪酸のクロマトグラフィ精製のための方法
CN107162910B (zh) 从鱼油中制备高纯度epa-ee的方法
EP0300844B1 (fr) Nouveaux glycérides d'acide gras insaturé et leurs procédés d'obtention
CN107922372A (zh) 从植物油馏出物回收生育酚/生育三烯酚、甘油、固醇和脂肪酸酯及其方法
CN120157575A (zh) 一种不饱和脂肪酸的制备方法
JP2014501228A (ja) 金属水素化物で多価不飽和脂肪酸を安定化するための方法
BR122024025185A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025211A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025183A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025187A2 (pt) Composição lipídica enriquecida derivada de óleo de semente
BR122024025192A2 (pt) Composição lipídica
ITMI20081200A1 (it) Procedimento di arricchimento per la preparazione di omega-3

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20140624

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid