KR20140111903A - Shampoo composition for improving hair loss containing dendropanax morbifera extract - Google Patents
Shampoo composition for improving hair loss containing dendropanax morbifera extract Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9755—Gymnosperms [Coniferophyta]
- A61K8/9761—Cupressaceae [Cypress family], e.g. juniper or cypress
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Abstract
Description
본 발명은 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물에 관한 것이다.
The present invention relates to a hair loss improving shampoo composition containing an extract of Hokkaido tree.
대한민국 공개특허 제2006-100514호(공개일자: 2006.9.21., 발명의 명칭: 삼푸 조성물 및 이의 제조방법)는 물 11.79중량%인 용제와; 코카미도 디에탄올아미드 7.0중량%와, 스테아릴 트리메틸 암모니움 클로라이 1.0중량%와, 소디움 라우일 에테르 설페이트 30.0중량%와, TEA-라우릴 설페이트 2.0중량%와, 디소디움 코코일 글루타메이트 2.0중량%와, 소디움 라우릴 설페이트 20.0중량%와, 코카미도프로필 베타인 10.0중량%를 포함하는 계면활성제와; 폴리쿼터니움-10 0.5중량%와, 소디움 클로라이드 1.0중량%를 포함하는 점증제와; 헤나 1.0중량%와, 글리세린 5.0중량%와, 소디움 3.0중량%와, 폴리쿼터니움 0.5중량%와, 글리콜 디스테아레이트 1.0중량%와, 실리콘 에멀젼(디메토콘 + 시클로메티콘) 1.0중량%와, 카모마일 추출물 1.0중량%와, 가수분해된 실크 1.0중량%를 포함하는 컨디셔닝제와; 디소디움 에틸렌 0.2중량%와, 디아민 테트라 아세테이트 0.2중량%를 포함하는 착염제와; 이미다조일다이닐 우레아 0.01중량%와, 메틸 파라벤 0.2중량%를 포함하는 방부제와; 방향물질 0.3중량%인 착향제와; 시트릭산 0.50중량%인 pH 조정제;를 혼합 구성하여 됨을 특징으로 하는 샴푸조성물이 제안되어 있다.Korean Unexamined Patent Publication No. 2006-100514 (date of publication: September 21, 2006, entitled "Sampu Composition and Process for its Preparation") comprises a solvent comprising 11.79% by weight of water; 7.0% by weight of cocamidodiethanolamide, 1.0% by weight of stearyltrimethylammonium chloride, 30.0% by weight sodium lauryl ether sulfate, 2.0% by weight of TEA-lauryl sulfate, 2.0% by weight of disodium cocoyl glutamate, A surfactant comprising 20.0% by weight of sodium lauryl sulfate and 10.0% by weight of cocamidopropyl betaine; 0.5% by weight of polyquaternium-10, and 1.0% by weight of sodium chloride; 1.0 wt% of henna, 5.0 wt% of glycerin, 3.0 wt% of sodium, 0.5 wt% of polyquaternium, 1.0 wt% of glycol distearate, 1.0 wt% of silicone emulsion (dimetalkone + cyclomethicone) 1.0% by weight of chamomile extract and 1.0% by weight of hydrolyzed silk; A complexing agent comprising 0.2% by weight of disodium ethylene and 0.2% by weight of diamine tetraacetate; A preservative comprising 0.01% by weight imidodynyl urea and 0.2% by weight methyl paraben; 0.3% by weight of an aromatic material; And a pH adjuster which is 0.50 wt% of citric acid.
이러한 종래 기술은 염색이나 퍼머 등으로 인해 손상된 모발에 탄력과 윤기를 더해주며 염색모의 색상이 오랫동안 지속시킬수 있도록 함은 물론 특히, 인체에 무해한 천연식물 재료의 하나인 헤나를 첨가하여 모발의 트리트먼트 효과를 향상시켜 줄 수 있는 매우 유용하다고 주장하고 있으나, 탈모 개선 효과가 미비하거나 없는 기술에 불과하다.
This prior art technique allows the hair to be dull or damaged due to permanent damage and gives the hair elasticity and shine, and the color of dyed hair can be maintained for a long time. In addition, henna, which is one of harmless natural plant material, But it is merely a technique that has little or no effect on improving hair loss.
대한민국 등록특허 제639421호(2006.10.20., 발명의 명칭: 탈모 방지용 샴푸 조성물 및 헤어팩 조성물)는 쿠퍼 펩타이드 2.0 ~ 5.0 wt%, 아르기닌 8.0 ~ 15.0 wt%, 비타민H 2.0 ~ 5.0 wt%, 히아루론산 0.08 ~ 2.0 wt%, 은행잎 추출물 0.5 ~ 2.0 wt%, 상표초 추출물 0.01 ~ 1.0 wt%, 백자인 추출물 0.01 ~ 1.0 wt%, 하수오 추출물 0.01 ~ 1.0 wt% 등이 유효성분으로 함유된 캡슐 0.2 ~ 10.0 wt%와; 헤나 추출물 1.0 ~ 3.0 wt%와; CPP 콤플렉스 0.01 ~ 10.0 wt% 및 샴푸조성물 77.0 ~ 98.79wt%로 이루어지는 것을 특징으로 하는 탈모방지용 샴푸 조성물이 제안되어 있다.The composition of the present invention comprises 2.0 to 5.0 wt% of Cooper peptide, 8.0 to 15.0 wt% of arginine, 2.0 to 5.0 wt% of vitamin H, 0.08 of hyaluronic acid 0.2 to 10.0 wt.% Of a capsule containing an effective ingredient, such as 2.0 wt.% Of Ginkgo biloba extract, 0.5 to 2.0 wt.% Of Ginkgo biloba extract, 0.01 to 1.0 wt.% Of branded primal extract, 0.01 to 1.0 wt. Wow; 1.0 to 3.0 wt% of a henna extract; 0.01 to 10.0 wt% of a CPP complex and 77.0 to 98.79 wt% of a shampoo composition.
그러나, 이러한 종래 기술은 쿠퍼 펩타이드에 의해 5α-Reductase의 활성을 억제하고, 다른 재료들이 두피에 영양을 공급하고, 혈액순환을 촉진함으로써 탈모를 방지할 수 있는 탁월한 효과가 있다고 주장하고 있으나, 실제 탈모 개선에 대한 실증적인 자료가 없는 단점이 있다.
However, this prior art claims that there is an excellent effect of inhibiting the activity of 5? -Reuctuctase by Cooper peptides and preventing hair loss by supplying nutrients to the scalp and promoting blood circulation by other materials, There is a lack of empirical data on the improvement.
대한민국 등록특허 제382602호(등록일자: 2003.4.18., 발명의 명칭: 탈모방지 및 모발생장 촉진 조성물)는 식품·영양학적인 재료로서 클로렐라 6.8∼7.6 중량%, 효모 4.1∼4.5 중량%, 백강잠 3.3∼3.9 중량%, 가지 1.8∼2.2 중량% 및 화분 4.6∼5.0 중량%를 함유하고, 생약으로서 하수오 3.2∼3.8 중량%, 대회향 3.2∼3.8 중량%, 호유자 4.0∼4.6 중량%, 백자인 2.6∼3.2 중량%, 저실자 2.4∼3 중량%, 천마 1.8∼2.2 중량%, 산약 1.8∼2.2 중량%, 지부자 5.4∼6.0 중량%, 동규자 4.1∼4.5 중량%, 목통 4.1∼4.5 중량%, 음양곽 4.1∼4.5 중량%, 천화분 2.7∼3.1 중량%, 황정 2.7∼3.1 중량%, 유근피 2.7∼3.1 중량%, 상백피 2.7∼3.1 중량%, 연전초 2.7∼3.1 중량%, 신이화 2.7∼3.1 중량%, 차전자 2.7∼3.1 중량%, 황기 2.7∼3.1 중량%, 후박 2.7∼3.1 중량%, 건강 2.7∼3.1 중량%, 퇴사자 1.8∼2.2 중량%, 파극 1.8∼2.2 중량%, 마자인 1.8∼2.2 중량% 및 오미자 2.8∼3.2 중량%를 포함하며, 전해질로서 해조회분 0.8∼1.1 중량%, 우골분 0.38∼0.42 중량%, 죽염 0.28∼0.42 중량%, 황산아연 0.08∼0.12 중량% 및 산화마그네슘 0.28∼0.32 중량%를 함유하여 우수한 탈모 예방효과 및 발모 촉진효과를 나타내는 조성물이 제안되어 있다.Korean Patent No. 382602 (registered on Apr. 18, 2003, title of the invention: hair loss prevention and hair growth promoting composition) is food and nutritional material containing 6.8-7.6% by weight of chlorella, 4.1-4.5% by weight of yeast, 3.3% 3.9% by weight, eggplant 1.8-2.2% by weight, and flowerpot 4.6-5.0% by weight, and the herbal medicine contains 3.2-3.8% by weight of hyssopressa, 3.2-3.8% by weight of horseradish, 4.0-4.6% by weight of horseradish, 2.6-3.3% By weight of starch, 2.4 to 3% by weight of starch, 1.8 to 2.2% by weight of chamois, 1.8 to 2.2% by weight of liquorice, 5.4 to 6.0% by weight of liquor, 4.1 to 4.5% by weight of cornstarch, 4.1 to 4.5% , 2.7 to 3.1 wt% of silicate, 2.7 to 3.1 wt% of silicate, 2.7 to 3.1 wt% of rhizome, 2.7 to 3.1 wt% of safflower, 2.7 to 3.1 wt% of silicate, 2.7 to 3.1 wt% 3.1% by weight of sulfur, 2.7-3.1% by weight of sulfur, 2.7-3.1% by weight of sprouts, 2.7-3.1% by weight of health, 1.8-2.2% by weight of desorbent, 1.8-2.2% 2.2% by weight of bamboo salt, 0.28% by weight to 0.42% by weight of bamboo salt, 0.08% by weight to 0.12% by weight of zinc sulfate and 0.28% by weight of magnesium oxide as electrolytes. To 0.32% by weight of the total weight of the composition, thereby exhibiting excellent hair loss preventing effect and hair growth promoting effect.
이러한 종래 기술은 신장 및 순환기 기능의 저하를 보강시켜 성별에 관계없이 우수한 탈모 예방효과 및 발모 촉진효과를 나타낼 뿐만 아니라 모발의 굵기를 증가시키는 효과를 나타내며 생체내에서 독성을 나타나지 않아 탈모 방지제 및 모발생장 촉진제로 유용하게 이용될 수 있다고 주장하고 있으나, 탈모 예방이나 발모 촉진에 검증되지 못한 한약재를 사용하고 있어 실제 발모 촉진 효과를 확인할 수 없는 문제점이 있다.
Such prior art reinforces the deterioration of the function of the kidney and the circulatory system, thereby exhibiting excellent hair loss preventing effect and hair growth promoting effect regardless of gender, and also exhibiting an effect of increasing the thickness of hair and does not show toxicity in vivo, However, there is a problem that the effect of accelerating the hair growth can not be confirmed because the herbal medicine is used for preventing hair loss or promoting hair growth.
대한민국 공개특허 제2009-59445호(공개일자: 2009.6.11., 발명의 명칭: 한약 추출물을 함유하는 양이온/음이온 계면활성제 혼합베시클을 함유하는 탈모 방지용 또는 모발 성장용 조성물)는 고삼, 당귀, 천궁, 감초, 들국화 및 의이인 추출물로 이루어진 군에서 선택된 5종 이상의 한방 추출물을 내부에 포함하는 이중층 구조의 양이온/음이온 계면활성제 혼합 베시클을 조성물 총 중량에 대하여 0.1 내지 0.2 중량%로 함유하는 탈모 방지 또는 모발 성장용 조성물이 제안되어 있다.Korean Patent Laid-Open Publication No. 2009-59445 discloses a composition for preventing hair loss or hair growth containing a mixed vial of a cationic / anionic surfactant containing a herbal medicine extract, Containing 0.1 to 0.2% by weight of a mixed-type bicomponent cation / anionic surfactant mixture containing at least five herbal extracts selected from the group consisting of licorice, licorice, licorice, Or compositions for hair growth have been proposed.
이러한 종래 기술은 상대적으로 적은 양의 한방 추출물을 두피 자극없이 전달하여 모낭세포 증식을 촉진하고 휴지기 모발주기에서 성장기 모발주기로의 이행을 촉진하는 효과가 있다고 주장하고 있으나, 혼합된 한방 추출물의 총 %만 기재되어 있어 각각의 한방 재료의 정확한 양을 알 수 없어 당업자 수준에서 용이하게 발명을 이용할 수 없는 문제점이 있었다.
Such prior art claims that a relatively small amount of herbal extract is delivered without scalp stimulation to promote hair follicle cell proliferation and promotes migration from the resting hair cycle to the growing hair cycle, but only the total% of the mixed herbal extract There is a problem that the exact amount of each herbal material can not be known and the invention can not be easily used at the level of a person skilled in the art.
상기와 같은 문제점을 해결하고자 창출된 본 발명의 목적은, 천연 계면활성제를 사용하여 민감성 두피의 자극을 최소화하고 탈모 개선 효과가 탁월한 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물을 제공하는 것을 목적으로 한다.
It is an object of the present invention, which is created to solve the above-mentioned problems, to provide a hair loss improving shampoo composition containing a extract of Hokkaido chrysanthemum extract having minimal stimulation of a sensitive scalp and excellent hair loss improving effect using a natural surfactant .
이러한 본 발명의 목적은, 정제수 100 중량부에 대하여, 디소듐라우레스설포석시네이트 0.30 ~ 1.10 중량부, 포타슘코코일글루타메이트 0.24 ~ 0.75 중량부, 소듐코코일글루타메이트 0.13 ~ 0.35 중량부, 코카마이드디이에이 0.15 ~ 0.40 중량부, 코카미도프로필베타인 3.5 ~ 5.00 중량부, 트리세틸모늄클로라이드 1.05 ~ 1.35 중량부, 아모디메치콘 0.12 ~ 0.15 중량부, 글리세린 2.00 ~ 3.05 중량부, 피이지-7글리세릴코코에이트 0.15 ~ 0.45 중량부, 소듐라우로일사르코시네이트 0.35 ~ 0.45 중량부, 코카마이드미파 1.23 ~ 1.25 중량부, 하이드로제네이티드폴리데센 0.25 ~ 0.37 중량부, 트리하이드록시스테아린 0.11 ~ 0.15 중량부, 피이지-60하이드로제네이티드캐스터오일 1.25 ~ 2.35 중량부, 피이지-150펜타에리스리틸테트라스테아레이트 1.00 ~ 1.21 중량부, 나이아신아마이드 0.5 ~ 1.0 중량부, 향료 0.1 ~ 0.3 중량부, 소듐하이알루로네이트 1.20 ~ 2.00 중량부, 알진 0.10 ~ 0.5 중량부, 폴리쿼터늄-10 0.4 ~ 0.6 중량부, 소듐데하이드로아세테이트 0.10 ~ 0.15 중량부, 하이드롤라이즈드케라틴 0.65 ~ 0.75 중량부, 판테놀 1.00 ~ 1.02 중량부, 메칠이소치아졸리논 0.02 ~ 0.03 중량부, 황칠나무추출물 8.50 ~ 13.5 중량부 및 한약추출물 8.50 ~ 13.5 중량부로 이루어진 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물에 의해 달성될 수 있다.It is an object of the present invention to provide a process for the preparation of a coconut oil composition which comprises, per 100 parts by weight of purified water, 0.30 to 1.10 parts by weight of disodium laureth sulfosuccinate, 0.24 to 0.75 part by weight of potassium cocoyl glutamate, 0.13 to 0.35 part by weight of sodium cocoyl glutamate, 0.15 to 0.40 parts by weight of dicyclohexylamine, 3.5 to 5.00 parts by weight of cocamidopropyl betaine, 1.05 to 1.35 parts by weight of tricetylmonium chloride, 0.12 to 0.15 parts by weight of amodimethicone, 2.00 to 3.05 parts by weight of glycerin, 0.15 to 0.45 parts by weight of glyceryl cocoate, 0.35 to 0.45 parts by weight of sodium lauroyl sarcosinate, 1.23 to 1.25 parts by weight of cocamidimide, 0.25 to 0.37 parts by weight of hydrogensified polydecene, 1.25 to 2.35 parts by weight of a fat-60 hydrogenated castor oil, 1.00 to 1.21 parts by weight of pentaerythrityl tetrastearate, 0.5 to 1.0 part by weight of niacinamide, 0.10 to 0.5 part by weight of algin, 0.4 to 0.6 part by weight of polyquaternium-10, 0.10 to 0.15 part by weight of sodium dehydroacetate, 0.1 to 0.5 part by weight of sodium hyaluronate, 0.85 to 0.75 parts by weight of panthenol, 1.00 to 1.02 parts by weight of panthenol, 0.02 to 0.03 parts by weight of methyl isothiazolinone, 8.50 to 13.5 parts by weight of the extract of Hokutogi and 8.50 to 13.5 parts by weight of the herbal medicine extract ≪ / RTI >
바람직하게는, 본 발명의 상기 황칠나무추출물은 11.5 내지 12.5 중량부인 것을 특징으로 한다.Preferably, the Horticultural Extract of the present invention is 11.5 to 12.5 parts by weight.
바람직하게는, 본 발명의 상기 한약추출물은 무환자나무열매추출물, 편백나무잎추출물, 하수오추출물, 구기자추출물, 감국추출물, 단삼뿌리추출물, 한련초추출물, 당귀추출물, 천궁추출물, 감초추출물로 이루어진 것을 특징으로 한다.
Preferably, the herbal medicine extract of the present invention is characterized in that it is composed of mulberry fruit extract, mulberry leaf extract, mulberry extract, gugija extract, mugwort extract, dansan root extract, do.
이상과 같은 본 발명의 조성은 머릿결이 한결 부드럽고 매끄러우며 머리결에 광체가 유지됨은 물론 항산화작용이 탁월하고 두피의 모세혈관을 튼튼하게 하여 혈액순환을 원활하게 하여 모근을 건강하고 단단하게 할 수 있는 특수한 효과가 있다.
As described above, the composition of the present invention is characterized in that the hair is more smooth and smooth, the hair is retained in the hair, the antioxidant activity is excellent, and the capillary blood vessels of the scalp are strengthened to smooth blood circulation, It is effective.
이하, 본 발명의 실시예를 설명하기로 한다.
Hereinafter, embodiments of the present invention will be described.
1. 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물 1. Anti-depilatory shampoo composition containing Hwangchujang extract
정제수 100 중량부100 parts by weight of purified water
디소듐라우레스설포석시네이트 0.30 ~ 1.10 중량부0.30 to 1.10 parts by weight disodium laureth sulfosuccinate
포타슘코코일글루타메이트 0.24 ~ 0.75 중량부Potassium cocoyl glutamate 0.24 to 0.75 part by weight
소듐코코일글루타메이트 0.13 ~ 0.35 중량부Sodium cocoyl glutamate 0.13-0.35 parts by weight
코카마이드디이에이 0.15 ~ 0.40 중량부0.18-0.40 parts by weight of cocamide di
코카미도프로필베타인 3.5 ~ 5.00 중량부3.5 to 5.00 parts by weight of cocamidopropyl betaine
트리세틸모늄클로라이드 1.05 ~ 1.35 중량부1.05-1.35 parts by weight tricetylmonium chloride
아모디메치콘 0.12 ~ 0.15 중량부0.12 to 0.15 part by weight of amodimethicone
글리세린 2.00 ~ 3.05 중량부Glycerin 2.00 to 3.05 parts by weight
피이지-7글리세릴코코에이트 0.15 ~ 0.45 중량부0.1 to 0.45 parts by weight of phage-7 glyceryl cocoate
소듐라우로일사르코시네이트 0.35 ~ 0.45 중량부0.35 to 0.45 parts by weight sodium lauroyl sarcosinate
코카마이드미파 1.23 ~ 1.25 중량부Cokamai demipara 1.23 to 1.25 parts by weight
하이드로제네이티드폴리데센 0.25 ~ 0.37 중량부Hydrogenated polydecene 0.25 to 0.37 part by weight
트리하이드록시스테아린 0.11 ~ 0.15 중량부0.1 to 0.15 parts by weight of trihydroxystearin
피이지-60하이드로제네이티드캐스터오일 1.25 ~ 2.35 중량부≪ tb > Pigment-60 < SEP > Hydrogenated castor oil <
피이지-150펜타에리스리틸테트라스테아레이트 1.00 ~ 1.21 중량부≪ tb > < tb > Pigment-150 < sep > Pentaerythrityl tetrastearate &
나이아신아마이드 0.5 ~ 1.0 중량부0.5 to 1.0 part by weight of niacinamide
향료 0.1 ~ 0.3 중량부0.1 to 0.3 parts by weight fragrance
소듐하이알루로네이트 1.20 ~ 2.00 중량부Sodium hyaluronate 1.20 to 2.00 parts by weight
알진 0.10 ~ 0.5 중량부0.10 to 0.5 parts by weight
폴리쿼터늄-10 0.4 ~ 0.6 중량부Polyquaternium-10 0.4 to 0.6 part by weight
소듐데하이드로아세테이트 0.10 ~ 0.15 중량부0.10 to 0.15 parts by weight of sodium dehydroacetate
하이드롤라이즈드케라틴 0.65 ~ 0.75 중량부0.65 to 0.75 parts by weight of hydrolyzed keratin
판테놀 1.00 ~ 1.02 중량부Panthenol 1.00 to 1.02 parts by weight
메칠이소치아졸리논 0.02 ~ 0.03 중량부0.02 to 0.03 part by weight of methyl isothiazolinone
황칠나무추출물 8.50 ~ 13.5 중량부Houttuynia bitera extract 8.50 - 13.5 parts by weight
한약추출물 8.50 ~ 13.5 중량부
Chinese medicine extract 8.50 ~ 13.5 parts by weight
여기서, 한약추출물은 무환자나무열매추출물, 편백나무잎추출물, 하수오추출물, 구기자추출물, 감국추출물, 단삼뿌리추출물, 한련초추출물, 당귀추출물, 천궁추출물, 감초추출물로 이루어진다.Here, the herbal medicine extracts are composed of mulberry fruit extract, mulberry leaf extract, mulberry extract, gugija extract, mugwort extract, dansan root extract, mulberry extract, ginseng extract, mulberry extract and licorice extract.
또한, 한약추출물 함량 중에서 편백나무잎추출물, 하수오추출물 및 구기자추출물은 전체 함량의 70% 이상을 포함하여야 본 발명이 구현하고자 하는 목적과 효과를 이룰 수 있다.
In addition, among the herbal medicine extracts, the extracts of Leuconostoc spider, leaf extract, and Gugija extract must contain 70% or more of the total content to achieve the object and effect to be achieved by the present invention.
2. 황칠나무추출물 및 한약추출물의 노법(露法) 추출 2. Extraction of Dahliaceae extract and Chinese medicine extract
한약재는 물을 끓여 다리는 일반 탕제 추출법을 사용하지만, 본 발명은 추출한 한약제를 한 번 더 가열하여 기화시킨 후 냉각한 무공해 자연 추출법으로 불순물을 걸러 가장 순수한 엑기스만을 추출할 수 있는 노법을 사용하였다.
However, in the present invention, the herb medicine is heated once more by vaporizing it, cooled, and then filtered using impure organic extraction method to extract only the purest extract.
3. 황칠나무의 효능 3. The efficacy of Hwangchil
황칠나무는 한국 특산식물인 황칠나무 (Dendropanax morbifera Lev.)는 두릅나무과의 난대성 상록수활엽수로 일본난대, 아열대 및 타이완에 분화 있으며 우리나라에서는 서남해안 및 도서지역인 제주도, 완도, 보길도, 해남, 거제도 등에 천연분포 하고 있다. 황칠나무는 학명에서 뜻하는 바와 같이 목본(Dendro) 전능약(panax) 이라는 의미가 있으며 (Korea Forest Service) 수형이 아름다워 조경수, 가로수등의 관상수로도 이용되고 있다.Dendropanax morbifera Lev. Is an evergreen deciduous broad-leaved tree of the Araliaceae. It is differentiated into Japanese habitat, subtropical and Taiwan. In Korea, it is divided into Jeju Island, Wando Island, Bogil Island, Haenam Island, And the like. It is called Dendro panax (Korea Forest Service) as it means in the scientific name. It is also used as ornamental water such as landscape garden and street tree.
황칠 수피의 유액은 천연도료로서, 잎은 항암제 및 면역 강화제(특히 황칠나무의 약효성분 가운데 하나인 베타엘레멘[베타- Elemene]은 인체의 중추신경계와 호르몬계에 영향을 주어 원기회복과 면역력 증진에 도움을 준다) 를 함유하고 있어 생리활성물질 자원이며, 황칠 수액 중 독특한 향을 내는 안식향산의 이용 등(항우울증, 스트레스해소, 기억력향상 기능성 검증 검증 동물실험완료) 남부난대 기후대의 대표적 경제수종으로서의 가치를 갖고 있는 것으로 알려져 있다.The emulsion of Huangchil bark is a natural paint, the leaf is an anticancer agent and an immunity enhancer (in particular Beta-Elemene, which is one of the medicinal components of Huangchu tree, affects the central nervous system and the hormone system of the human body, (Antidepressant, relieving stress, verifying the function of memory and verifying the animal test), as a representative economic species in the southern part of the warming zone. . ≪ / RTI >
황칠은 수령 15년 정도의 흉고 직경이 10cm 이상인 개체에서만 수액체취가 가능한데 체취시기도 7~9월의 더운 여름에 국한되어 수액이 매우 어려우며 그 양도 매우 소량이라는 한계점을 가지고 있다. 황칠은 아름다운 황금빛이 나는 천연 투명 도료로서 옛 백제의 특산물이었으며 조선시대에도 부채나 화선지 등에 칠로서 사용되었고 특히 황칠을 한 목공예품은 높이 평가 되었다. 황칠은 금빛을 띠면서도 바탕의 나무결을 생생하게 떠오르게 하여 목공예품를 한층 화사하게 치장하는 최상의 도료일 뿐만 아니라 락카나 옻칠과는 달리 항파단성이 있어 부채에도 칠할 수 있는 장점이 있다. 이러한 황칠의 우수성 때문에 황칠을 한 것만이 우리의 전통공예품이 라고 주장하는 사람도 있다.
Hwalchil is able to take sap from only individuals with a chest diameter of 10cm or more, which is about 15 years of age. It is confined to the hot summer of 7th to 9th of September and has a very low amount of sap and its amount is very small. Hwalchil is a beautiful golden painted transparent paint, which was a special product of old Baekje. It was also used as a paint for fans and flower pots in Chosun Dynasty. Huangchil is not only the best paint to embellish wooden crafts with brightly colored wood but also has the advantage that it can be painted on the fan because it has anti-irregularity like lacquer and lacquer. Some people argue that it is only our traditional handicrafts that are made of yellow crest because of the excellence of these.
황칠나무는 중국 당태종이 백제에 사신을 보내어 구할 정도로 귀하게 사용되었고 명나라 이시진이 저술한 본초강목(本草綱目)에는 황칠나무가 번열 (몸에 열이 몹시나고 가슴 속이 답답하며 괴로운 증세)제거, 술해독, 안질 및 황달 치료, 화상치료, 나병치료 등에 효과가 있음이 기술되어 있다.(이시진, 본초강목, 중국 문광도서, 1590).Hwangchil was used to the extent that the Chinese Taejong was sent to the Baekje to save its envoys, and the Ming Dynasty, which was published by the Ming Dynasty, It is described that it is effective for detoxification, eye and jaundice treatment, burn treatment, leprosy treatment, etc. (Ishin Jin, Basho Gangmok, Munhwang Book, 1590).
그러나 황칠나무의 성분에 관한 연구는 아직까지 황칠나무의 수지성분에 대한 초보적인 내용만 있을 뿐 황칠을 대상으로 항암 또는 항산화 활성 등의 약리 활성 물질에 대한보고는 국내외적으로 전혀 없었다. 또한 최근에 비로소 황칠나무의 자생지 분포와 자생지 환경조건 등에 대한 기초적인 조사도 이루어 졌다.(정병석등, 한국생물공학회 10: 393, 1995)
However, studies on the composition of Hwangchu - wood have not yet been reported on the phyto - active substances such as anticancer or antioxidant activity of Hwangchil. In recent years, basic research on the distribution of native habitat and native habitat has been conducted (Jung, Byeongseok et al., Korea Biotechnology Society 10: 393, 1995)
상기에 기술한 바와 같이 황칠 나무가 약용으로서 사용 될 수 있는 점과 옻칠 목제품이 오래된 유적지에서 원형이 보존된 형태로 발굴되는 등의 내구성을 고려하면 황칠에는 다양한 약리활성물질이 존재할 것이 기대된다.As described above, it is expected that various kinds of pharmacologically active substances will be present in Huangchil in consideration of durability such that Huchulchu can be used as a medicinal substance and durability such as a lacquered wood product is discovered in a form in which a circular shape is preserved in an old historical site.
이외에도 황칠은 옻칠과 달리 피부 알레르기를 거의 유발하지 않고 취급이 용이 하므로 기능성화장품 및 샴푸 헤어케어제품, 의약품뿐만 아니라 식품으로도 널리 이용될 수 있다. 따라서, 황칠나무에 함유된 약리 활성물질을 분리하는 경우 기능성화장품, 의약품 등에 이용하는 것뿐만 아니라 편백나무잎추출물, 홍삼 추출액 등과 같이 약리 활성물질을 포함하는 황칠나무 추출물은 다양한 제품에 이용될 수 있다.
In addition, unlike lacquer, Hwangchil does not induce skin allergy and it is easy to handle, so it can be widely used as functional cosmetics, shampoo hair care products, medicines as well as foods. Therefore, when extracting the pharmacologically active substance contained in Hwangchujang, it is not only used for functional cosmetics, pharmaceuticals, etc., but also extracts of Hwangchulchae including pharmacologically active substances such as scurvy leaf extract and red ginseng extract can be used for various products.
본 발명자는 황칠나무로부터 새로운 약리활성 물질을 확인 하고자 연구한 결과 황칠나무 추출물에서 피를 맑게 하고 혈액순환을 개선과 항산화(노화와 세포손상 억제) 활성을 확인하고 이를 메탄올로 추출하거나 이에 더하여 다양한 유기 용매 및 이를 사용한 칼럼 크로마토그래피로 분획하여 황칠나무 추출물을 제조한 다음 이를 신기능성화장품, 샴푸, 헤어제품, 의약품, 음료 및 식품 등에 이용하도록 함으로서 본 발명을 완성하였다.
The present inventors have studied to identify new pharmacologically active substances from yellowtail, and found that the extract of Hwangchuki extract has clear blood, improves blood circulation and antioxidant activity (aging and cell damaging inhibitory activity), extracts it with methanol, Solvent and column chromatography using the same to prepare an extract of Huangchil tree, which is then used in new functional cosmetics, shampoo, hair products, medicines, beverages and foods.
4. 황칠나무 추출물을 함유한 탈모개선 삼푸의 효능 4. Efficacy of alopecia improved shampoo containing extract
본 발명에 의한 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물에는 정제수 100 중량부에 대하여 황칠나무추출물 8.50 ~ 13.5 중량부 및 한약추출물 8.50 ~ 13.5 중량부이 함유되어 있다.
The anti-depilatory shampoo composition containing the extract of Tochigi extract according to the present invention contains, in 100 parts by weight of purified water, 8.50 to 13.5 parts by weight of the extract of Hwaseum japonica and 8.50 to 13.5 parts by weight of the extract of the herb medicine.
(가) 두피/모발 청결효과 및 피부 자극(A) Scalp / hair cleansing effect and skin irritation
본 발명의 조성물에 의한 샴푸와 일반 화학성분 샴푸의 청결효과 및 피부 자극 테스트를 수행함에 있어, 10 내지 50대까지 각 연령별 10명씩 피부 트러블이 심하지 않는 여성을 선출하여 하루 2회에 걸쳐 화학 샴푸와 본 발명의 샴푸를 실제 사용하였다.In performing the cleaning effect and the skin irritation test of the shampoo and the general chemical component shampoo by the composition of the present invention, a woman who does not have severe skin troubles was selected by 10 persons by each age from 10 to 50, and the chemical shampoo The shampoo of the present invention was actually used.
샴푸의 청결효과 및 피부 자극은 화학 샴푸를 10점 만점 기준으로 하여 본 발명의 조성물에 의한 샴푸의 청결도 및 피부 자극을 측정하였다.The cleansing effect of the shampoo and the skin irritation were measured on the cleanliness and the skin irritation of the shampoo by the composition of the present invention based on the chemical shampoo as a scale of 10 points.
여기서, 만족도는 여성 피실험자의 최종 만족도를 나타내는 것으로 "매우 나쁨", "나쁨", "보통", "좋음" 및 "매우 좋음"의 5 단계로 평가되었다.Here, the satisfaction rate was evaluated as five levels of "very bad", "bad", "normal", "good" and "very good" indicating the final satisfaction level of female subjects.
표 1을 참조하면, 본 발명에 의해 제조된 샴푸는 청결효과가 일반 화학 샴푸와 동일한 청결효과를 나타내고 있으며 피부 자극에 있어서는 자극이 거의 없는 것으로 나타났음은 물론, 만족도에서도 전연령에서 모두 "매우좋음"의 평가를 받았다.
Referring to Table 1, the shampoo manufactured according to the present invention exhibits the same cleanliness effect as that of the general chemical shampoo, and shows little irritation in skin irritation. I was evaluated.
(나) 탈모방지 개선효과(B) Hair loss prevention effect
먼저, 탈모가 진행중인 40 내지 50대 장년 100명을 5명씩 20개 그룹으로 나누어 테스트를 진행하였다.First, the test was carried out by dividing into 100 groups of 20 to 40 persons in their 40s and 50s who were in the process of hair loss.
여기서, 정상적인 남성은 하루에 50 내지 100개 정도의 머리카락이 빠지는 것으로 보고되어 있으나, 본 테스트에 선발된 남성들은 모두 150 내지 200개 정도 탈모되는 사람만을 선출하였다.Here, normal men are reported to lose about 50 to 100 hairs per day, but all of the men selected for this test have selected only about 150 to 200 hairs.
테스트 방법은 본 발명에 의한 샴푸를 14일 동안 사용한 다음, 15일째부터 하루에 한 번씩 본 발명의 샴푸를 사용한 후 탈모된 개수를 계수하여 20일째까지 6일간 테스트를 진행하였다.In the test method, the shampoo according to the present invention was used for 14 days, and after the use of the shampoo of the present invention every day from day 15, the number of unhairing was counted and the test was performed for six days until the 20th day.
테스트 결과는 다음 4 등급으로 나누어진다.Test results are divided into four grades.
"매우좋음" 탈모 개수: 100 ~ 110개"Very good" Number of hair loss: 100 to 110
"좋음" 탈모 개수: 111 ~ 135개"Good" Number of hair loss: 111 to 135
"보통" 탈모 개수: 136 ~ 145개"Normal" Number of hair loss: 136 ~ 145
"나쁨" 탈모 개수: 146 이상"Bad" Number of hair loss: 146 or more
본 발명의 탈모개선 테스트가 15일째부터 진행한 이유는, 테스트 각자 마다 두피의 건강상태나 청결도가 일정하지 않기 때문에 미리 본 발명의 샴푸를 이용하여 일정기간, 예컨대 14일 정도 사용한 후 테스트를 진행한 것이다.
The reason why the hair loss improvement test of the present invention has been carried out since the 15th day is that since the health condition and the cleanliness of the scalp are not constant for each test, the test was conducted using the shampoo of the present invention for a predetermined period, will be.
표 2를 참조하면, 본 발명의 샴푸를 14일 사용한 다음 탈모개수를 계수한 결과 적어도 "좋음" 이상의 결과를 획득한 바, 본 발명의 샴푸는 탈모개선 효과가 탁월한 것으로 판명되었다.
Referring to Table 2, when the shampoo of the present invention was used for 14 days and the number of hair loss was counted, it was found that the shampoo of the present invention was superior in at least "good".
이상과 같은 본 발명은 일 실시예에 한정되어 설명되었으나, 이에 한정되지 않고 본 발명의 기술적 사상을 토대로 변형되는 실시예들은 모두 본 발명의 권리범위에 속함이 분명하다.While the present invention has been described with reference to exemplary embodiments, it is to be understood that the invention is not limited to the disclosed exemplary embodiments.
Claims (3)
0.30 to 1.10 parts by weight of disodium laureth sulfosuccinate, 0.24 to 0.75 part by weight of potassium cocoyl glutamate, 0.13 to 0.35 part by weight of sodium cocoyl glutamate, 0.15 to 0.40 parts by weight of cocamide dielite, 3.5 to 5.00 parts by weight of cocamidopropyl betaine, 1.05 to 1.35 parts by weight of tricetylmonium chloride, 0.12 to 0.15 parts by weight of amodimethicone, 2.00 to 3.05 parts by weight of glycerin, 0.15 to 0.45 parts by weight of glyceryl cocoate 0.35 to 0.45 parts by weight of sodium lauroyl sarcosinate, 1.23 to 1.25 parts by weight of cocamidimide, 0.25 to 0.37 parts by weight of hydrogensified polydecene, 0.11 to 0.15 parts by weight of trihydroxystearin, 1.25 to 2.35 parts by weight of hydrogenated castor oil, 1.00 to 1.21 parts by weight of penta-150 pentaerythrityl tetrastearate, 0.5 to 1.0 parts by weight of niacinamide, 0.1 to 0.3 parts by weight of fragrance, 1.20 to 2.00 parts by weight of ruronate, 0.10 to 0.5 parts by weight of algin, 0.4 to 0.6 parts by weight of polyquaternium-10, 0.10 to 0.15 part by weight of sodium dehydroacetate, 0.65 to 0.75 part by weight of hydrolyzed keratin, 1.02 parts by weight of methyl isothiazolinone, 0.02 to 0.03 part by weight of methyl isothiazolinone, 8.50 to 13.5 parts by weight of the extract of Hwangchujang and 8.50 to 13.5 parts by weight of the herbal extract.
상기 황칠나무추출물은 11.5 내지 12.5 중량부인 것을 특징으로 하는 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물.
The method according to claim 1,
Wherein the extract is from 11.5 to 12.5 parts by weight.
상기 한약추출물은 무환자나무열매추출물, 편백나무잎추출물, 하수오추출물, 구기자추출물, 감국추출물, 단삼뿌리추출물, 한련초추출물, 당귀추출물, 천궁추출물, 감초추출물로 이루어진 것을 특징으로 하는 황칠나무 추출물을 함유한 탈모개선 삼푸 조성물.The method according to claim 1,
Wherein the herbal extract is selected from the group consisting of mulberry tree extract, mulberry leaf extract, mulberry leaf extract, mulberry extract, mulberry leaf extract, danshin root extract, Improvement of hair loss.
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