KR102427088B1 - Cosmetic composition for hair damage repair - Google Patents

Abstract

The present invention provides a natural weakly acidic shampoo composition which comprises plant-derived surfactants, natural surfactants, and natural extracts with antioxidant effects. The natural weakly acidic shampoo composition enhances the homeostasis of the scalp and immunity and strengthens hair roots with a high percentage of antioxidants. In addition, the composition induces the normalization and activation of cell division for hair regeneration and has a hair loss prevention function.

Description

Natural weakly acidic shampoo composition with scalp immunity strengthening, antioxidant and hair loss prevention functions {COSMETIC COMPOSITION FOR HAIR DAMAGE REPAIR}

The present invention relates to a natural weakly acidic shampoo composition having a function of preventing hair loss by inducing strengthening of hair follicle cells and normal activation of hair regenerative cells by composing a strong antioxidant component ratio at the maximum content while maintaining the formulation of the shampoo and strengthening the scalp immunity. .

The hair of modern people is contaminated by UV exposure, contact with the surrounding environment such as dust, and sebum secreted from the hair follicles. Scalp diseases such as keratin and dandruff and the resulting hair loss often damage the scalp and hair.

When the homeostasis of the scalp is lowered, the immunity of the scalp is lowered, scalp diseases appear, and the damage to the hair is accelerated due to the deterioration of the function of the regeneration cells of the scalp hair root area. Damaged hair, when wet or dry, is hard to handle due to tangles and stiffness, which makes it difficult to comb, and shows an unsightly appearance due to lack of luster. Accordingly, consumer demand and preference for hair care products (eg, shampoo, conditioner, hair conditioner, hair treatment, etc.) that improve the appearance and feel of hair and make it easier to handle are increasing day by day.

Conventionally, hair care products such as hair conditioner, hair treatment, and hair air conditioner have been used to give moisture or smoothness to hair, and in general, anionic surfactants and polymers, silicone conditioning agents, hydrocarbon oils and fats You are using a hair conditioning agent such as alcohol.

Among them, silicone oil is widely used because of its low surface tension, excellent familiarity with hair, and good gloss. However, silicone oil has a problem of causing scalp troubles by clogging the scalp or pores and preventing the smooth secretion of sebum.

There are many types of shampoos, treatments, and hair packs sold in the market, but most of them contain a lot of chemical ingredients such as surfactants and silicone-derived ingredients to temporarily increase the shine and silkiness of hair. However, shampoos, treatments, and hair packs with these ingredients have better cleaning power as they contain a lot of strong alkaline ingredients, but the residue remains on the scalp and hair and penetrates into the body, causing adverse effects on the body, such as the accumulation of transdermal toxins and the generation of carcinogens. also do

Therefore, development of shampoos, treatments and hair pegs containing natural ingredients that have a good effect on hair or scalp is being made. In particular, as the number of hair loss populations increases in recent years, studies on shampoos having a hair loss prevention and hair growth function are being actively conducted. If the ratio of plant-derived surfactants, weakly acidifying ingredients, and natural active ingredients is increased as much as possible, the formulation of the shampoo becomes unstable and has an uncomfortable feeling of use. Consumers also have limited consumption due to uncomfortable feeling compared to efficacy.

Normal hair and scalp pH is 4.5~5.5, which is weakly acidic, and the possibility of weak acidity maintains homeostasis to protect itself from harmful environments such as external bacteria, bacteria, dust, rapid temperature and humidity changes, and strong UV rays. However, if you use strong alkali products that emphasize cleaning power, the normal pH of the scalp and hair is broken, losing homeostasis and becoming vulnerable to external harmful environments, causing scalp diseases and hair loss. Hair is partially dissolved in a strong alkaline solution, and even a weak alkaline component is easily changed during heating if it remains in the hair, so always keep in mind the isoelectric point. Conversely, hair becomes hard in strong acid. Therefore, the development of a product free from these problems is also required. It is necessary to develop a shampoo composition product that maintains the natural weak acidity of the scalp and hair, activates the scalp cells normally, and maintains healthy scalp immunity and homeostasis, while providing a convenient formulation and excellent combination ratio of refined fragrance.

Republic of Korea Patent Publication No. 2014-0086673

The present invention has been devised to solve the above disadvantages of the prior art,

An object of the present invention is to provide a natural weakly acidic shampoo composition having a function of preventing hair loss by strengthening scalp homeostasis and immunity, strengthening hair root cells with the maximum content ratio of strong antioxidant components, and normalizing and activating hair regeneration cell division.

In order to achieve the above object, the present invention

Sodium lauryl sulfate 15 to 25% by weight, cocamidopropylbetaine 13 to 23% by weight, cocamide DA 5 to 15% by weight, decylglucoside 2 to 7% by weight, laurylglucoside 2 to 7% by weight, potassium coco 2 to 7% by weight of ylglycinate, and 0.1 to 3% by weight of distearyldimonium chloride;

0.01 to 0.03% by weight of water extract of chlorella powder, 0.01 to 0.03% by weight of water extract of kelp powder, 0.01 to 0.03% by weight of water extract of brewer's yeast powder, 0.01 to 0.03% by weight of water extract of sewage powder, water extract of Centella asiatica powder 0.01 to 0.03% by weight, 0.01 to 0.03% by weight of water extract of yulpi powder, 0.01 to 0.03% by weight of water extract of mung bean powder, 0.01 to 0.03% by weight of water extract of mung bean powder, 0.01 to 0.03% by weight of water extract of dermis powder, 0.01 to 0.03% by weight of water extract of broccoli powder, 0.01 to 0.03% by weight of water extract of lotus leaf powder, 0.01 to 0.03% by weight of water extract of Angelica powder, 0.01 to 0.03% by weight of water extract of golden powder, water extract of apricot seed powder 0.01 to 0.03% by weight, 0.01 to 0.03% by weight of water extract of sweet pumpkin powder, 0.01 to 0.03% by weight of water extract of licorice powder, 0.01 to 0.03% by weight of water extract of cacao powder, 0.01 to 0.03% by weight of water extract of wormwood powder, 0.01 to 0.03% by weight of water extract of green tea powder, 0.01 to 0.03% by weight of water extract of lavender powder, 0.01 to 0.03% by weight of water extract of blue seaweed powder, 0.01 to 0.03% by weight of water extract of oatmeal powder, water extract of paprika powder 0.01 to 0.03% by weight, 0.01 to 0.03% by weight of water extract of tomato powder, and 0.01 to 0.03% by weight of dimethylsulfone;

0.1 to 0.4% by weight of natural betaine, 0.1 to 0.4% by weight of trehalose, and 0.05 to 0.3% by weight of allantoin;

0.1 to 0.5% by weight of citric acid;

1 to 2% by weight of glucamate, 0.1 to 0.4% by weight of polyquats, and 0.2 to 0.6% by weight of cocamide, 0.2 to 0.6% by weight of lecithin;

Seoritae water extract 0.3 to 0.7 wt%, kelp water extract 0.3 to 0.7 wt%, noni water extract 0.3 to 0.7 wt%, calendula water extract 0.3 to 0.7 wt%, chamomile water extract 0.3 to 0.7 wt%, aloe water extract 0.3 to 0.7% by weight, 0.3 to 0.7% by weight of ginseng water extract, 0.3 to 0.7% by weight of peony water extract, 0.3 to 0.7% by weight of cheongung water extract, 0.3 to 0.7% by weight of Espinozilia water extract, 0.3 to 0.7% by weight of water extract , Centella asiatica water extract 0.3 to 0.7% by weight, Eoseongcho water extract 0.3 to 0.7% by weight, propolis water extract 0.3 to 0.7% by weight, rosemary water extract 0.3 to 0.7% by weight, peppermint water extract 0.3 to 0.7% by weight, orchid water extract 0.3 to 0.7% by weight, Goji berry water extract 0.3 to 0.7% by weight, Injin mugwort water extract 0.3 to 0.7% by weight, basil water extract 0.3 to 0.7% by weight, broccoli water extract 0.3 to 0.7% by weight, Zimo water extract 0.3 to 0.7% by weight , 0.3 to 0.7% by weight of seaweed water extract, 0.3 to 0.7% by weight of lemon water extract, 0.3 to 0.7% by weight of henna water extract, 0.3 to 0.7% by weight of natto moist, 0.3 to 0.7% by weight of beta glucan, and 0.3 to 0.3% by weight of seokchangpo water extract to 0.7% by weight;

1 to 4% by weight of glycerin, 0.5 to 2% by weight of hyaluronic acid, 1 to 4% by weight of silk amino acid, 0.5 to 2% by weight of MPO (2-Methyl-1,3-Propanediol), 0.5 to 2% by weight of acacia collagen, urea 0.05 to 0.4% by weight, and 0.5 to 2% by weight of dexpanthenol;

0.2 to 0.6 wt% of menthol, 0.05 to 0.2 wt% of camellia oil, 0.1 to 0.4 wt% of grape seed oil, 0.05 to 0.2 wt% of apricot seed oil, 0.05 to 0.2 wt% of jojoba oil, 0.05 to 0.2 wt% of evening primrose seed oil , cyclomethicone 0.05 to 0.2% by weight, MCT oil 0.05 to 0.2% by weight, olive ester oil 0.05 to 0.2% by weight, upper point oil 0.05 to 0.2% by weight;

0.1 to 0.4% by weight of olive liquid, 0.1 to 1.5% by weight of lecithin, and 0.1 to 0.4% by weight of Glycerol Mono stearate (GMS);

1 to 3% by weight of a preservative;

0.1 to 1.5% by weight of fragrance oil; and

Provided is a natural weakly acidic shampoo composition having functions of strengthening scalp immunity, antioxidant and preventing hair loss, including the remaining amount of purified water.

The natural weakly acidic shampoo composition of the present invention contains ingredients extracted from various kinds of natural products, thereby strengthening the hair follicle cells and inducing normalization and activation of hair follicle cell division and hair regenerative cell division and preventing hair loss with excellent scalp homeostasis and immunity enhancement, strong antioxidant ingredients to provide.

Hereinafter, the present invention will be described in detail.

The natural weakly acidic shampoo composition that strengthens the scalp immunity and induces normalization and activation of hair follicle cell division and hair regeneration cell division with the strong antioxidant component of the present invention, and has the function of preventing hair loss

As a hypoallergenic plant-derived surfactant derived from coconut and palm oil, 15 to 25% by weight of sodium lauryl sulfate, 13 to 23% by weight of cocamidopropyl betaine, 5 to 15% by weight of cocamide DEA, shampoo composition, sugar beet, As a natural surfactant derived from corn, coconut, palm oil, and fruit sugar, it has excellent biodegradability and cleaning power, does not clog pores because it does not leave residues, has excellent moisturizing properties, is almost non-irritating, and is an eco-friendly raw material containing 2 to 7% by weight of decylglucoside; 2 to 7% by weight of lauryl glucoside, 2 to 7% by weight of potassium cocoyl glycinate, 0.1 to 3% by weight of distearyldimonium chloride for shampoo composition, antibacterial and antistatic and hair conditioning functions;

As an antioxidant functional powder component of the shampoo composition, 0.01 to 0.03 wt% of a water extract of chlorella powder, 0.01 to 0.03 wt% of a water extract of kelp powder, 0.01 to 0.03 wt% of a water extract of brewer’s yeast powder, 0.01 to 0.03 wt% of a water extract of sewage powder %, 0.01 to 0.03% by weight of water extract of Centella asiatica powder, 0.01 to 0.03% by weight of water extract of yulpi powder, 0.01 to 0.03% by weight of water extract of mung bean powder, 0.01 to 0.03% by weight of water extract of ginseng root powder, water of dermis powder 0.01 to 0.03% by weight of extract, 0.01 to 0.03% by weight of water extract of broccoli powder, 0.01 to 0.03% by weight of water extract of lotus leaf powder, 0.01 to 0.03% by weight of water extract of Angelica powder, 0.01 to 0.03% by weight of water extract of golden powder , 0.01 to 0.03% by weight of water extract of apricot seed powder, 0.01 to 0.03% by weight of water extract of sweet pumpkin powder, 0.01 to 0.03% by weight of water extract of licorice powder, 0.01 to 0.03% by weight of water extract of cacao powder, water of mugwort powder 0.01 to 0.03% by weight of extract, 0.01 to 0.03% by weight of water extract of green tea powder, 0.01 to 0.03% by weight of water extract of lavender powder, 0.01 to 0.03% by weight of water extract of blue seaweed powder, 0.01 to 0.03% by weight of water extract of oatmeal powder %, 0.01 to 0.03% by weight of a water extract of paprika powder, 0.01 to 0.03% by weight of a water extract of tomato powder, and 0.01 to 0.03% by weight of dimethylsulfone;

0.1 to 0.4% by weight of natural betaine, 0.1 to 0.4% by weight of trehalose, and 0.05 to 0.3% by weight of allantoin as a nourishing moisturizing soothing conditioning component;

0.1 to 0.5% by weight of citric acid as a pH adjuster;

1 to 2% by weight of glucamate, 0.1 to 0.4% by weight of polyquater, 0.2 to 0.6% by weight of cocamide, and 0.2 to 0.6% by weight of lecithin as an antioxidant natural thickener;

As an antioxidant, scalp nutrition, and scalp anti-inflammatory component, 0.3 to 0.7% by weight of seoritae water extract, 0.3 to 0.7% by weight of kelp water extract, 0.3 to 0.7% by weight of noni water extract, 0.3 to 0.7% by weight of calendula water extract, 0.3% by weight of chamomile water extract to 0.7 wt%, aloe water extract 0.3 to 0.7 wt%, ginseng water extract 0.3 to 0.7 wt%, peony water extract 0.3 to 0.7 wt%, cheongung water extract 0.3 to 0.7 wt%, Espinozilia water extract 0.3 to 0.7 wt% %, self-inflicted water extract 0.3 to 0.7% by weight, Centella asiatica water extract 0.3 to 0.7% by weight, eoseongcho water extract 0.3 to 0.7% by weight, propolis water extract 0.3 to 0.7% by weight, rosemary water extract 0.3 to 0.7% by weight, peppermint water 0.3 to 0.7% by weight of extract, 0.3 to 0.7% by weight of water extract of Orchids, 0.3 to 0.7% by weight of Goji berry water extract, 0.3 to 0.7% by weight of Injin mugwort water extract, 0.3 to 0.7% by weight of basil water extract, 0.3 to 0.7% by weight of broccoli water extract %, 0.3 to 0.7% by weight of water extract, 0.3 to 0.7% by weight of seaweed extract, 0.3 to 0.7% by weight of lemon water extract, 0.3 to 0.7% by weight of henna water extract, 0.3 to 0.7% by weight of natto moist, 0.3 to beta glucan to 0.7% by weight, and 0.3 to 0.7% by weight of a seokchangpo water extract;

As a moisturizing agent, glycerin 1 to 4% by weight, hyaluronic acid 0.5 to 2% by weight, silk amino acid 1 to 4% by weight, MPO (2-Methyl-1,3-Propanediol) 0.5 to 2% by weight, acacia collagen 0.5 to 2% by weight , 0.05 to 0.4% by weight of urea, and 0.5 to 2% by weight of dexpanthenol;

As antioxidant nourishing scalp care oil, menthol 0.2 to 0.6% by weight, camellia oil 0.05 to 0.2% by weight, grape seed oil 0.1 to 0.4% by weight, apricot seed oil 0.05 to 0.2% by weight, jojoba oil 0.05 to 0.2% by weight, evening primrose seed seed 0.05 to 0.2% by weight of oil, 0.05 to 0.2% by weight of cyclomethicone, 0.05 to 0.2% by weight of MCT oil, 0.05 to 0.2% by weight of olive ester oil, 0.05 to 0.2% by weight of top point oil;

As an antioxidant natural emulsifier, 0.1 to 0.4% by weight of olive liquid, 0.1 to 1.5% by weight of lecithin, and 0.1 to 0.4% by weight of Glycerol Mono stearate (GMS);

1 to 3% by weight of a preservative; 0.1 to 1.5% by weight of fragrance oil; and a residual amount of purified water.

The antioxidant functional extract, antioxidant scalp nutrition and scalp anti-inflammatory component are extracted in powder form by shredding the dried components, adding water and boiling for 0.1 to 3 hours, filtering the extract, and concentrating and drying the filtered extract. can be manufactured with In addition, each of the antioxidant functional extract, antioxidant, scalp nutrition, and scalp anti-inflammatory component, it is also possible to put all the components at once and extract with water.

In one embodiment of the present invention, the preservative is 0.3 to 1% by weight of golden water extract, 0.1 to 0.4% by weight of 1,2-hexanediol, 0.05 to 0.3% by weight of tocopherol acetate, 0.05 to 0.3% by weight of ethylhexylglycerin , 0.05 to 0.3% by weight of EDTA, 0.1 to 0.7% by weight of sodium benzoate, 0.1 to 0.7% by weight of potassium sorbate, 0.05 to 0.3% by weight of a preservative comprising caprylic acid and caprylyl glycol, and 0.1% by weight of grapefruit extract to 0.4% by weight.

As a preservative containing the capryl hydroxamic acid and caprylyl glycol, a mixture of capryl hydroxamic acid and capryllyl glycol in a weight ratio of 4:6 to 6:4 may be used.

In one embodiment of the present invention, the fragrance oil is an antioxidant regenerating scalp care aroma essential oil Peppermint E.O, Rosemary E.O, Ylang Ylang E.O, Cedarwood E.O, Geranium E.O, Lavender E.O, Lemon E.O, Orange E.O, Citronella E.O, Eucalyptus E.O, Frankincense E.O, Tea Tree E.O, Melissa E.O, Lemongrass E.O, Pine E.O, and sophisticated and refreshing artificial fragrances of the highest safety grade and quality, Lilac F.O, Doson F.O, Bay F.O, Cherry F.O, Jasmine F.O, and NenoliF.O may each comprise 0.02 to 0.06 wt%.

In one embodiment of the present invention, the shampoo composition may further comprise 0.3 to 5.0% by weight of Arctic willow root extract.

The arctic willow (Salix arctica) grows in tundra and rocky wastelands, and is the northernmost tree plant in the world. Arctic willows are distributed in the northern territories of Canada, from the Arctic archipelago to Elesmere Island with Greenland, northern Quebec and Labrador, northern Iceland, Penno Scandinavia, northern Russia and northern Alaska.

The arctic willow is a low shrub, typically only 15 cm tall, but can reach 50 cm in height in the Pacific Northwest. Despite their small size, the arctic willow is a very slow-growing long-lived plant in harsh Arctic climates. In eastern Greenland, 236-year-old arctic willows have also been found.

The present inventors have found that when the root extract of Arctic willow is included in the shampoo composition together with the above ingredients, the antibacterial, antioxidant and hair loss prevention effects are greatly improved.

Arctic willow root extract according to the present invention extracts dried Arctic willow root with a solvent mixed with ethanol and butylene glycol in a weight ratio of 1:9 to 5:5, preferably 2:8 to 4:6 . The extraction may be carried out at 50 to 60 ℃.

After obtaining the Arctic willow root extract, it is filtered, concentrated, and dried to obtain the Arctic willow root extract.

Components used in the shampoo composition of the present invention that are not described in detail above are components commonly used in this field. Therefore, it can be easily used by purchasing it from the market.

Hereinafter, the present invention will be described in more detail through examples. However, the following examples are provided to explain the present invention in more detail, and the scope of the present invention is not limited by the following examples. The following examples can be appropriately modified and changed by those skilled in the art within the scope of the present invention.

Preparation Example 1: Preparation of powder extract

(1) Chlorella, kelp, brewer's yeast, dimethyl sulfone, succulents, Centella asiatica, yulpi, mung bean, jasmine root, dermis, broccoli, lotus leaf, angelica, golden, apricot seed, sweet pumpkin, licorice, cacao, mugwort, green tea, lavender, cheonghae Water extracts of each powder of vinegar, oatmeal, paprika, and tomato were prepared in the following way.

1 kg of the dried powder component was put in 2L of water and extracted for 0.5 hours while boiling. The extract was filtered under reduced pressure with a vacuum pump and Whatman No. 2 filter paper, and the filtered extract was concentrated with a vacuum rotary concentrator and dried to obtain a powdery extract.

(2) Seoritae, kelp, noni, calendula, chamomile, aloe, ginseng, peony, chrysanthemum, espinozilia, self-inflicted herb, Centella asiatica, eoseongcho, propolis, rosemary, peppermint, nasturtium, wolfberry, wormwood, basil, broccoli, thyme, The water extracts of each of the seaweed, lemon, henna, and sagebrush were prepared by the following method.

After shredding 1 kg of the dried component, it was put into 2L of water and extracted for 0.5 hours while boiling. The extract was filtered under reduced pressure with a vacuum pump and Whatman No. 2 filter paper, and the filtered extract was concentrated with a vacuum rotary concentrator and dried to obtain a powdery extract.

Preparation Example 2: Preparation of Arctic Willow Root Extract

After chopping 1 kg of dried Arctic willow root, put it in 2L of a mixed solvent of ethanol (concentration 40% (v/v)) and butylene glycol (weight ratio 3:7), and stir at 50 to 60° C. for 4 hours while extracted. The extract was filtered under reduced pressure with a vacuum pump and Whatman No. 2 filter paper, the filtered extract was concentrated with a vacuum rotary concentrator, and the solvent was evaporated to obtain a powdery arctic willow root extract.

Experimental Example 1: Safety evaluation

The stability of the extract prepared in Preparation Example 2 was tested through a 48-hour patch test using Guinea Pig. The degree of irritation was evaluated and the results are shown in Table 1 below.

<Evaluation criteria>

○: Non-irritating (there is almost no erythema and edema)

△: mild irritation (very mild erythema and edema)

×: moderate irritation (moderate edema and obvious erythema)

Properties Preparation 2 pepper ○

As shown in Table 1, the extract of Preparation Example 2 was confirmed to be safe for skin.

Experimental Example 2: Confirmation of antibacterial activity of Arctic willow extract

The antibacterial activity of the Arctic willow extract prepared in Preparation Example 2 was evaluated as follows.

Representative food poisoning bacteria (Bacillus cereus, Bacillus subtilis, Campylobacter jejuni, Escherichia coli, Escherichia coli O-157, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella enteritidis, Salmonella thypimurium, Vibrio parahaemolyticus) were used.

The bacteria were inoculated with 50 μl of the culture in 10 ml of sterile TSB medium and subcultured at 30° C. for 24±1 hours. The concentration of this culture was maintained at an Abs 0.6±0.1 at an absorption wavelength of 655 nm in a microplate reader. The subcultured experimental bacteria were diluted 10 ^-3 times with sterile distilled water, and the disc diffusion method was performed. That is, the diluted strain was put on a sterile cotton swab and spread on a 4 mm thick plate medium, and a sterilized 8 mm (thickness 1 mm) paper was raised and 50 μl of the Arctic willow extract was injected. After sufficient inhalation for about 20 minutes, culture was performed at 30°C for 24±1 hours, and growth rings were confirmed.

The antibacterial activity was evaluated by measuring the size of the translucency including the filter paper, and the results are shown in Table 2 below.

strain name strain number ^a Arctic Willow Extract bacteria Bacillus cereus KCTC 1012 16 Bacillus subtilis KCCM 1021 17 Campylobacter jejuni KCCM 41772 17 Escherichia coli ATCC 25922 17 Escherichia coli O-157 ATCC 43888 16 Listeria monocytogenes ATCC 15313 16 Pseudomonas aeruginosa KCTC 1750 16 Staphylococcus aureus ATCC 25923 17 Salmonella enteritidis KCCM 11862 16 Salmonella thypimurium ATCC 13076 16 Vibrio parahaemolyticus ATCC 17802 17 Yersinia enterocolitica ATCC 23715 18

Co., Ltd. ^a : ATCC American Type Culture Collection, KCTC Korea Research Institute of Bioscience and Biotechnology Biological Resources Center; KCCM (Korea Sprinkler Association) ^b : Size of transparencies (diameter mm)

As can be seen in Table 2 above, the Arctic willow extract exhibited excellent antibacterial activity against all bacteria.

Example 1: Preparation of shampoo composition

A shampoo composition was prepared by adding a plant-derived surfactant, a natural surfactant, an oil phase component and a preservative to the aqueous component of Table 3 below, and stirring at a speed of 200 to 300 rpm for 3 hours.

Plant-derived surfactant
and natural surfactants 65% Sodium Lauryl Sulfate 20%, Cocamidopropyl Betaine 16.5%,
Cocamide DEA 10%,
Decyl glucoside 6%, lauryl glucoside 6%, potassium cocoyl glycinate 6%, distearyldimonium chloride 0.5% Awards Purified water 5% Antioxidant and nutrition
powdered water extract 0.5%

Chlorella, kelp, brewer's yeast, dimethyl sulfone, hawthorn, centella asiatica, yulpi, mung bean, ginseng root, dermis, broccoli, lotus leaf, angelica, golden, apricot seed, sweet pumpkin, licorice, cacao, wormwood, green tea, lavender, blue seaweed, oatmeal , paprika, tomato
0.02% of the water extract of the powder of each component Nutritional moisturizing soothing conditioning ingredient 0.5% Natural Betaine 0.2%, Trehalose 0.2%, Allantoin 0.1% pH adjustment Weak acidity 0.3% citric acid 0.3% Scalp care antioxidant thickener 2.1% Glucamate 1.2%, Polyquat 0.2%, Cocamide 0.4%, Lecithin 0.3% Antioxidant, scalp nutrition,
Scalp anti-inflammatory care water extract 13.2% Seoritae, kelp, noni, calendula, chamomile, aloe, ginseng, peony, chrysanthemum, espinozilia, self-inflicted herb, Centella asiatica, eoseongcho, propolis, rosemary, peppermint, nasturtium, wolfberry, wormwood, basil, broccoli, jimo, hagocho, Lemon, henna, and water extract 0.48% of each ingredient
Natto Moist and Beta Glucan 0.36% each nutritional moisturizer 8.2% Glycerin 2%, hyaluronic acid 1%, silk amino acid 2%, MPO 1%, acacia collagen 1%, urea 0.2%, dexpanthenol 1% paid Antioxidant nourishing scalp care oil 1.4% Menthol 0.4%, camellia oil 0.1%, grape seed oil 0.2%, apricot seed oil 0.1%, jojoba oil 0.1%, evening primrose seed oil 0.1%, cyclomethicone 0.1%, MCT oil 0.1%, ester oil 0.1%, and Top oil 0.1% Antioxidant natural emulsifier, emulsion stabilizer One % Olive Liquid 0.2%, Lecithin 0.6%, GMS 0.2% Antioxidant, regenerating aroma essential oil (E.O) and cosmetic grade fragrance oil (F.O) 0.80% Peppermint E.O, Rosemary E.O, Ylang Ylang E.O, Cedarwood E.O, Geranium E.O, Lavender E.O, Lemon E.O, Orange E.O, Citronella E.O, Eucalyptus E.O, Frankincense E.O, Tea Tree E.O, Melissa E.O, Lemongrass E.O, Pine E.O, Lilac F.O, Dawson F.O, Bay F.O, Cherry F.O, Jasmine F.O, and Nenoli F.O 0.02~0.06% each Antioxidant, natural preservative, metal ion antioxidant 2.0% Gold 0.6%, 1,2-hexanediol 0.2%, tocopherol acetate 0.1%, ethylhexylglycerin 0.1%, EDTA 0.1%, sodium benzoate 0.3%, potassium sorbate 0.3%, SPT 0.1%, grapefruit extract 0.2%

(Unit: % by weight)

Note) SPT (Preservative containing Caprylhydroxamic acid and Caprylyl Glycol, manufactured by INOLEX, USA)

Example 2: Preparation of Shampoo Composition

A shampoo composition was prepared in the same manner as in Example 1, except that in Example 1, sodium lauryl sulfate among the plant-derived surfactants was reduced to 16% by weight, and 4% by weight of the Arctic willow root extract was further added.

Comparative Example 1.

Head and Shoulders Itchy Scalp Total Solution Shampoo, which is a commercially available weak acid hair loss shampoo, was used as Comparative Example 1.

Experimental Example 3: Scalp immunity and antioxidant effect evaluation

1) Subject selection

Fifteen women aged 20-59 years with damaged hair, with a sensitive scalp with a scalp pH index of 5.6 or higher, scalp redness, itching, dandruff, and dead skin cells were selected as subjects.

2) Test method

After wetting the scalp and hair with lukewarm water, apply the shampoo of Example 1 (5 people), Example 2 (5 people) and Comparative Example 1 (5 people) to the hands in an amount of 3 ml to 10 ml, and wash the hands. Make bubbles by rubbing. Next, the shampoo with foam was applied to the scalp and hair, and then washed with lukewarm water.

3) Test result

(1) Scalp pH measurement

In order to check the change in scalp pH, the scalp pH was measured before, immediately after, and 2 weeks after use of the shampoo, and the results of 5 people in each group were averaged and shown in Table 4 below.

Scalp pH (Mean±SD) Example 1 Example 2 Comparative Example 1 before use 5.78±0.12 5.80±0.13 5.79±0.11 immediately after use 5.62±0.14 5.45±0.15 5.72±0.13 2 weeks after use 5.61±0.11 5.39±0.12 5.72±0.15

* : P<0.05 by repeated measure ANOVA, post hoc Bonferroni correction

(2) Scalp keratin measurement

In order to check the changes in scalp keratin, scalp keratin was measured before, immediately after, and 2 weeks after use of the shampoo, and the results of 5 people in each group were averaged and shown in Table 5 below.

Scalp keratin (Mean±SD) Example 1 Example 2 Comparative Example 1 before use 14.88±3.88 14.95±3.65 14.90±3.65 immediately after use 10.21±2.63 10.01±2.21 12.78±211 2 weeks after use 8.01±2.44 7.98±2.32 12.12±3.21

* : P<0.05 by repeated measure ANOVA, post hoc Bonferroni correction

Experimental Example 4: Measurement of antioxidant activity

(1) Analysis of total polyphenol content

Examples 1, 2 and Comparative Example 1 To measure the antioxidant activity of shampoos, 50 μl of folin-ciocalteu reagent was added to 0.1 ml of each shampoo, mixed, and reacted for 4 minutes, followed by 1.5 ml of 20% saturated anhydrous sodium carbonate solution was added. After reaction for 2 minutes, absorbance was measured at 760 nm using a microplate reader (VERSAmax, Molecular Device, CA, USA). The total polyphenol content was calculated from a standard curve prepared using chlorogenic acid.

(2) DPPH radical scavenging activity measurement

After adding 160 μl of DPPH solution dissolved in methanol to a concentration of 0.4 mM and 40 μl of each shampoo sample, leaving it for 30 minutes in the dark, absorbance was measured at 515 nm using a microplate reader (VERSAmax, Molecular Device, CA, USA). .

Example 1 Example 2 Comparative Example 1 Total polyphenol mg/ml 57.1 62.0 42.3 DPPH R S (%) 76 82 62.8

Experimental Example 5: Evaluation of the effect of preventing hair loss

Examples 1, 2 and Comparative Example 1 In order to confirm the hair loss prevention effect of the shampoo, 5 out of 15 male test subjects with alopecia were used in units of Example 1, Example 2 and Comparative Example 1 shampoo. The hair was washed once a day for months, and the results of use were evaluated and shown in Table 7.

<Evaluation criteria>

The amount of hair loss during hair washing, subjective symptoms, and visual judgment were evaluated as 5 points if the effect was significant, 4 points for moderate, 3 points for mild, 2 points for unchanged, and 1 point for worsening hair loss symptoms. Comprehensive judgment was made as an average value.

Example 1 Example 2 Comparative Example 1 Amount of hair loss when washing hair 4.4 4.8 3.7 subjective symptoms 4.2 4.6 3.5 Visual judgment 4.3 4.6 3.4 Synthesis 4.3 4.6 3.53

Claims (4)

Sodium lauryl sulfate 15 to 25% by weight, cocamidopropylbetaine 13 to 23% by weight, cocamide DA 5 to 15% by weight, decylglucoside 2 to 7% by weight, laurylglucoside 2 to 7% by weight, potassium coco 2 to 7% by weight of ylglycinate, and 0.1 to 3% by weight of distearyldimonium chloride;
0.01 to 0.03% by weight of water extract of chlorella powder, 0.01 to 0.03% by weight of water extract of kelp powder, 0.01 to 0.03% by weight of water extract of brewer's yeast powder, 0.01 to 0.03% by weight of water extract of sewage powder, water extract of Centella asiatica powder 0.01 to 0.03% by weight, 0.01 to 0.03% by weight of water extract of yulpi powder, 0.01 to 0.03% by weight of water extract of mung bean powder, 0.01 to 0.03% by weight of water extract of mung bean powder, 0.01 to 0.03% by weight of water extract of dermis powder, 0.01 to 0.03% by weight of water extract of broccoli powder, 0.01 to 0.03% by weight of water extract of lotus leaf powder, 0.01 to 0.03% by weight of water extract of Angelica powder, 0.01 to 0.03% by weight of water extract of golden powder, water extract of apricot seed powder 0.01 to 0.03% by weight, 0.01 to 0.03% by weight of water extract of sweet pumpkin powder, 0.01 to 0.03% by weight of water extract of licorice powder, 0.01 to 0.03% by weight of water extract of cacao powder, 0.01 to 0.03% by weight of water extract of wormwood powder, 0.01 to 0.03% by weight of water extract of green tea powder, 0.01 to 0.03% by weight of water extract of lavender powder, 0.01 to 0.03% by weight of water extract of blue seaweed powder, 0.01 to 0.03% by weight of water extract of oatmeal powder, water extract of paprika powder 0.01 to 0.03% by weight, 0.01 to 0.03% by weight of a water extract of tomato powder, and 0.01 to 0.03% by weight of dimethylsulfone;
0.1 to 0.4% by weight of natural betaine, 0.1 to 0.4% by weight of trehalose, and 0.05 to 0.3% by weight of allantoin;
0.1 to 0.5% by weight of citric acid;
1 to 2 wt% glucamate, 0.1 to 0.4 wt% polyquater, 0.2 to 0.6 wt% cocamide, 0.2 to 0.6 wt% lecithin;
Seoritae water extract 0.3 to 0.7 wt%, kelp water extract 0.3 to 0.7 wt%, noni water extract 0.3 to 0.7 wt%, calendula water extract 0.3 to 0.7 wt%, chamomile water extract 0.3 to 0.7 wt%, aloe water extract 0.3 to 0.7% by weight, 0.3 to 0.7% by weight of ginseng water extract, 0.3 to 0.7% by weight of peony water extract, 0.3 to 0.7% by weight of cheongung water extract, 0.3 to 0.7% by weight of Espinozilia water extract, 0.3 to 0.7% by weight of water extract , Centella asiatica water extract 0.3 to 0.7% by weight, Eoseongcho water extract 0.3 to 0.7% by weight, propolis water extract 0.3 to 0.7% by weight, rosemary water extract 0.3 to 0.7% by weight, peppermint water extract 0.3 to 0.7% by weight, orchid water extract 0.3 to 0.7% by weight, Goji berry water extract 0.3 to 0.7% by weight, Injin mugwort water extract 0.3 to 0.7% by weight, basil water extract 0.3 to 0.7% by weight, broccoli water extract 0.3 to 0.7% by weight, Zimo water extract 0.3 to 0.7% by weight , 0.3 to 0.7% by weight of seaweed water extract, 0.3 to 0.7% by weight of lemon water extract, 0.3 to 0.7% by weight of henna water extract, 0.3 to 0.7% by weight of natto moist, 0.3 to 0.7% by weight of beta glucan, and 0.3 to 0.3% by weight of seokchangpo water extract to 0.7% by weight;
Glycerin 1-4 wt%, hyaluronic acid 0.5-2 wt%, silk amino acid 1-4 wt%, MPO (2-Methyl-1,3-Propanediol) 0.5-2 wt%, acacia collagen 0.5-2 wt%, urea 0.05 to 0.4% by weight, and 0.5 to 2% by weight of dexpanthenol;
0.2 to 0.6 wt% of menthol, 0.05 to 0.2 wt% of camellia oil, 0.1 to 0.4 wt% of grape seed oil, 0.05 to 0.2 wt% of apricot seed oil, 0.05 to 0.2 wt% of jojoba oil, 0.05 to 0.2 wt% of evening primrose seed oil , cyclomethicone 0.05 to 0.2% by weight, MCT oil 0.05 to 0.2% by weight, olive ester oil 0.05 to 0.2% by weight, upper point oil 0.05 to 0.2% by weight;
0.1 to 0.4% by weight of olive liquid, 0.1 to 1.5% by weight of lecithin, and 0.1 to 0.4% by weight of Glycerol Mono stearate (GMS);
Golden water extract 0.3 to 1% by weight, 1,2-hexanediol 0.1 to 0.4% by weight, tocopherol acetate 0.05 to 0.3% by weight, ethylhexylglycerin 0.05 to 0.3% by weight, EDTA 0.05 to 0.3% by weight, sodium benzoate 0.1 to 0.7% by weight, potassium sorbate 0.1 to 0.7% by weight, capryl hydroxamic acid and 0.05 to 0.3% by weight of a mixture of caprylhydroxamic acid and caprylyl glycol in a 4:6 to 6:4 weight ratio, and 1 to 3% by weight of a preservative comprising 0.1 to 0.4% by weight of grapefruit extract;
0.1 to 1.5% by weight of fragrance oil; and
A natural weakly acidic shampoo composition with a pH of 4.5 to 5.5 that has functions of strengthening scalp immunity, antioxidant and preventing hair loss, containing the remaining amount of purified water. delete According to claim 1,
The fragrance oils are Peppermint EO, Rosemary EO, Ylang Ylang EO, Cedarwood EO, Geranium EO, Lavender EO, Lemon EO, Orange EO, Citronella EO, Eucalyptus EO, Frankincense EO, Tea Tree EO, Melissa EO, Lemongrass EO, Pine EO, Lilac FO, Doson FO, Bay FO, Cherry FO, Jasmine FO, and Nenoli FO, each containing 0.02 to 0.06% by weight of the scalp immunity strengthening, antioxidant and hair loss prevention function A natural weakly acidic shampoo composition having a pH of 4.5 to 5.5. According to claim 1,
The shampoo composition is a natural weakly acidic shampoo composition having a pH of 4.5 to 5.5 having functions of strengthening scalp immunity, antioxidant and preventing hair loss, characterized in that it further comprises 0.3 to 5.0% by weight of Arctic willow root extract.