KR20130114468A - Cosmetic compositon for hair and method for hair tretments using the same - Google Patents

Abstract

PURPOSE: A cosmetic composition for hair is provided to repair damaged hair and to strengthen hair, thereby improving hair gloss, moisture, smoothness, elasticity, thickness, and volume. CONSTITUTION: A cosmetic composition for hair contains one or more kinds selected among carbodiimide-based compounds, fatty acid N-hydroxysuccinimide ester, sulfo-N-hydroxysuccinimide, pyridyl disulfide-based compounds, and maleimide compounds. The carbodiimide-based compounds are denoted by chemical formula 1. The fatty acid N-hydroxysuccinimide ester is denoted by chemical formula 2. The cosmetic composition contains: a first agent containing one or more kinds selected among carbodiimide-based compounds, fatty acid N-hydroxysuccinimide ester, sulfo-N-hydroxysuccinimide, pyridyl disulfide-based compounds, and maleimide compounds; and a second agent containing one or more kinds selected among amino acids, peptides, proteins, and enzymes.

Description

Cosmetic composition for hair and hair treatment method using same {COSMETIC COMPOSITON FOR HAIR AND METHOD FOR HAIR TRETMENTS USING THE SAME}

The present invention relates to a hair cosmetic composition for repairing and strengthening damaged hair and a hair treatment method using the same.

Generally, hair is composed of keratin protein containing about 14-18% of cysteine among 18 kinds of amino acids.

These keratin proteins can maintain very strong binding under mild conditions such as water or neutral solvents, but can be easily damaged by physical / chemical treatments on hair such as combing in everyday life, heat by hair dryers, dyeing, and perming. Can be. As a result, damaged hair may be eluted with protein inside, which may lead to porosity, coarse hair, loss of elasticity, difficulty in grooming due to increased friction, and easy cutting or splitting. .

In order to solve these problems, research on the development of a cosmetic composition for hair for repairing and strengthening damaged hair continues.

 For example, Korean Patent Laid-Open Publication No. 2007-0038509 discloses a cosmetic containing amino, amino acid or peptide conjugates of retinoic acid, which has a disadvantage in that the effect is significantly lowered and not sustained by washing. In addition, U.S. Patent No. 5,490,980, 356,7915, and Japanese Patent Publication No. 2003-026543 include transglutaminase which can form an isopeptide bond between lysine and glutamine among amino acids. The cosmetic composition for hair is disclosed, respectively. However, since the transglutase is an enzyme having a macromolecule having a molecular weight of about 38 kDa, it is difficult to act on the damaged part of the hair that requires substantial structural enhancement, and thus the effect is very limited.

Accordingly, the present invention is to provide a cosmetic composition for hair that can effectively recover and strengthen not only the outside of the damaged hair but also the inside.

In addition, the present invention is to provide a hair treatment method using the composition.

According to one embodiment of the invention, it is selected from the group consisting of carbodiimide compounds, fatty acid N-hydroxysuccinimide esters, sulfo N-hydroxysuccinimides, pyridyldisulfide compounds, and maleimide compounds There is provided a hair cosmetic composition comprising at least one compound.

According to another embodiment of the present invention, the hair cosmetic composition may further include one or more compounds selected from the group consisting of amino acids, peptides, proteins, and enzymes.

In addition, the cosmetic composition for hair may be a hair tonic, hair nourishing cosmetics, hair essence, hair serum, hair treatment, hair conditioner, hair shampoo, hair lotion, hair cream, hair styling agent, hair coloring agent, or hair bleaching agent. .

On the other hand, according to another embodiment of the present invention, there is provided a hair treatment method comprising the step of applying the hair cosmetic composition to the hair.

The cosmetic composition for hair according to the present invention enables restoration and reinforcement of damaged hair inside and outside, and can impart an increasing effect such as gloss, moisturizing, smoothness, elasticity, thickness, and volume of hair.

Hereinafter, the hair cosmetic composition and the hair treatment method using the same according to the embodiments of the present invention will be described.

Prior to this, the term "comprise" or "contains" throughout this specification refers to the inclusion of any component (or component) without particular limitation, and should not be construed to exclude or exclude the addition of other components.

On the other hand, the present inventors in the course of repeating the study on the cosmetic composition for hair, carbodiimide compound, fatty acid N-hydroxysuccinimide ester, sulfo N-hydroxysuccinimide, pyridyl disulfide-based compound, and Malay One or more compounds selected from the group consisting of mid-based compounds can form peptide bonds or disulfide bonds with the hair, and in particular, it has been confirmed that the reinforcement and repair for the inside and outside of the damaged hair can be completed, thereby completing the present invention.

According to an embodiment of the present invention,

For hair comprising at least one compound selected from the group consisting of carbodiimide compounds, fatty acid N-hydroxysuccinimide esters, sulfo N-hydroxysuccinimides, pyridyldisulfide compounds, and maleimide compounds A cosmetic composition is provided.

Here, the carbodiimide-based compounds may be a compound represented by the following formula (1):

[Formula 1]

In Formula 1, R ¹ and R ² may be each independently a linear or branched hydrocarbon having 1 to 22 carbon atoms, the hydrocarbon may be an olefinic or cyclic hydrocarbon, alkyl quaternization at the end of the hydrocarbon It may be a functional group containing a nitrogen atom in the form of a cation.

In addition, in the present invention, the fatty acid N-hydroxysuccinimide ester may be a compound represented by the following Formula 2:

(2)

In Formula 2, R ³ may be a straight or branched hydrocarbon having 1 to 22 carbon atoms, and the hydrocarbon may be an olefin-based or cyclic hydrocarbon.

In addition, in the present invention, the sulfo N-hydroxysuccinimide may be a compound represented by the following Chemical Formula 3:

(3)

And, in the present invention, the pyridyl disulfide compound may be a compound represented by the following formula (4):

[Formula 4]

In Formula 4, R ⁴ may be hydrogen, a hydrocarbon having 1 to 22 carbon atoms or a straight chain or branched chain, or a pyridyl group; The hydrocarbon may be an olefinic or cyclic hydrocarbon.

In addition, in the present invention, the maleimide compound may be a compound represented by Formula 5 below:

[Chemical Formula 5]

In Formula 5, R ⁵ may be hydrogen, or a straight or branched hydrocarbon having 1 to 22 carbon atoms, and the hydrocarbon may be an olefinic or cyclic hydrocarbon.

Hereinafter, with reference to the reaction scheme, the action of the compounds that can be included in the composition according to the embodiment will be described.

First, among the above compounds that may be included in the composition of the present invention, carbodiimide-based compounds, aspartic acid (peptide or protein) present in the amino acids, peptides or protein molecules constituting the hair, as shown in Scheme 1 below ( It forms an intermediate by combining with carboxylic acid groups of amino acids such as aspartic acid) and glutamic acid.

The intermediate formed forms a peptide bond with the primary amine present in the hair or in another amino acid, peptide or protein molecule supplied externally, which may result in strengthening and repairing effects on the inside and outside of the damaged hair (Scheme 1). -①).

In addition, the intermediate is obtained by the reaction with N-hydroxysuccinimide added as needed amino acid, peptide or protein of the form of the N-hydroxysuccinimide ester structure Lose. Compounds having such structures form peptide bonds with primary amines present in the hair or in other amino acids, peptides or protein molecules supplied externally such that the strengthening and restoring effects on the inside and outside of the damaged hair can be exhibited. (Scheme 1-③).

[Reaction Scheme 1]

Meanwhile, among the compounds that may be included in the composition of the present invention, sulfo N-hydroxysuccinimide is present in amino acids, peptides, or protein molecules constituting hair, as shown in Scheme 2 below. To form an intermediate by combining with carboxylic acid groups of amino acids such as aspartic acid, glutamic acid and the like. The intermediate formed forms a peptide bond with the primary amine present in the hair or in another amino acid, peptide or protein molecule supplied externally, which may result in strengthening and repairing effects on the inside and outside of the damaged hair.

[Reaction Scheme 2]

In addition, pyridyldisulfide based compounds and maleimide based compounds among the compounds that may be included in the composition of the present invention, as shown in Schemes 3 and 4 below, are present in the hair. By forming a disulfide bond or a sulfide bond by reacting with an amino acid, a peptide or a protein such as a cysteine having a thiol group, the strengthening and repairing effects on the inside and outside of the damaged hair may be exhibited.

Scheme 3

[Reaction Scheme 4]

Here, according to the present invention, in order to facilitate the reactions of the reaction schemes 1 to 4 as described above, it is necessary to maintain appropriate reaction conditions such as pH, viscosity, salt concentration. Therefore, the hair cosmetic composition according to the present invention may include additional components such as acids, bases, salts, viscosity modifiers and the like to provide a suitable reaction environment. At this time, the acid, base, salt, viscosity modifiers and the like may be used in the art, which is common in the art, the kind is not particularly limited. In addition, the addition amount of the above components may also be determined within a range that allows the reaction to be accelerated, so it is not particularly limited.

In addition, the compounds of Formulas 1 to 5, which may be included in the composition of the present invention, may be modified to maintain activity in the composition using methods such as coating, encapsulation, dispersion, dissolution, emulsification, and the like. Here, the coating, encapsulation, dispersion, dissolution, emulsification, etc. may be carried out by applying a conventional method in the art to which the present invention belongs within a range that does not reduce the reactivity of the compound, it is not particularly limited to specific methods Do not.

On the other hand, the cosmetic composition for hair of the present invention, while allowing the reaction according to the reaction scheme 1 to 4 may be made more smoothly, may further include a component that can play a role of reinforcing the hepatic substances in damaged hair tissue.

That is, in the above Reaction Schemes 1 to 4, amino acids, peptides or proteins having a primary amine group (compound represented by Prot-NH ₂ in the scheme) are present inside the hair, or induced or synthesized by a microorganism or the like to be supplied from the outside. If the amount is not sufficient, the above-described reaction may not be performed smoothly.

Therefore, in order to make the reaction more smoothly, the composition according to the present invention may further include one or more compounds selected from the group consisting of amino acids, peptides, proteins, and enzymes.

At this time, in view of the effect of improving the reactivity, the additional compound may be a peptide consisting of several to several tens of amino acids, for example 1 to 18, preferably 1 to 9, more preferably 1 to 5 It may be a peptide consisting of amino acids.

In addition, the peptide may be an oligopeptide having an average molecular weight of 100 to 2000 Daltons, preferably 120 to 1000 Daltons, more preferably 120 to 500 Daltons. Although there is a difference in the degree of damage and treatment conditions due to the histological characteristics of the hair, such peptides are most effective in penetrating into the hair and restoring damage to the hair. However, even in the case of having a molecular weight that is impossible to penetrate into the hair, since the bond between amino acids can be formed from the outside of the hair, it can be expected to strengthen and repair the damaged hair both inside and outside.

On the other hand, among the compounds of Formulas 1 to 5 included in the composition according to the present invention, in particular when any one of the compounds of Formulas 1 to 3 is used as a peptide for the role of hepatic reinforcement in damaged hair tissue aspartic acid, glutamic acid As such, it is preferable to include the carboxy terminus at the amino acid residue. In forming the amino acid residue bond, in the case of the compounds of Formulas 1 and 2, in particular, aspartic acid, glutamic acid, etc., including carboxyl groups are primarily formed, and the intermediate formed is arginine, lysine, or histidine. In the case of containing a cationized nitrogen atom such as (histidine), it has the property of primarily binding, and in the case of peptides composed of two or more amino acids, at least one aspartic acid, glutamic acid, arginine, lysine, or histidine Including residues is advantageous because it can form more bonds.

In addition, when any one of the compounds of Formulas 4 and 5 is included, it has a characteristic of forming a bond by reacting with cysteine, and in the case of a peptide composed of two or more amino acids, at least one cysteine residue is included. It is advantageous to be able to form more bonds.

On the other hand, when the composition according to the present invention further comprises one or more compounds selected from the group consisting of amino acids, peptides, proteins, and enzymes as described above, before applying the composition to the hair of the formula 1 to 5 In order to ensure long-term storage stability, such as to prevent the reaction with the compound, the compound of Formula 1 to 5 and the additional compound is preferably included in a separated state.

According to one embodiment of the present invention, the hair cosmetic composition is a carbodiimide compound, fatty acid N-hydroxysuccinimide ester, sulfo N-hydroxysuccinimide, pyridyldisulfide-based compound, and maleimide-based A first agent comprising at least one compound selected from the group consisting of compounds; And a second agent comprising at least one compound selected from the group consisting of amino acids, peptides, proteins, and enzymes.

Herein, the method of separately including the first agent and the second agent is not particularly limited because a conventional method may be applied in the art to which the present invention pertains. For example, the components included in the first agent may be described above. Coating or encapsulation, as described, may be dispersed in a composition comprising a second agent. Also, for example, the composition of the second agent may be applied to the hair first, and then used as a method of applying the composition of the first agent. By applying the cosmetic composition for hair to the hair through such a method, the first agent and the second agent are allowed to react, thereby ensuring long-term storage stability and improving reactivity.

Such a cosmetic composition for hair of the present invention is a hair tonic, hair nourishing cosmetics, hair essence, hair serum, hair treatment, hair conditioner, hair shampoo, hair lotion, hair cream, hair styling agent, hair coloring agent, or hair bleaching agent And various formulations.

At this time, in applying the composition of the present invention to the formulation, water, organic solvent, pH adjuster, penetration aid, thickener, stabilizer, surfactant, conditioning agent, appearance according to the physical properties required for each formulation and the effect to be given Various additives may be included such as enhancers, fragrances, preservatives, dyes, pigments, metal ion sequestrants.

On the other hand, according to another embodiment of the present invention, there is provided a hair treatment method comprising the step of applying the aforementioned cosmetic composition for hair to the hair.

The hair treatment method is applied to the hair cosmetic composition having the above-described formulation to the hair, in particular to enable the repair and strengthening of the damaged hair and the inside and outside, hair shine, moisturizing, smoothness, elasticity, thickness, volume, etc. The increase effect of can be given.

Here, the specific hair treatment method may vary depending on the formulation of the cosmetic composition for hair to be used, which is not particularly limited since it may be in accordance with conventional methods in the art to which the present invention belongs.

Best Mode for Carrying Out the Invention Hereinafter, preferred embodiments are described to facilitate understanding of the present invention. However, the following examples are only for illustrating the present invention and may be modified in various other forms, and the scope of the present invention is not limited only to the following examples.

Example  And Comparative Example

As shown in Table 1 below, the compositions of Examples 1 to 5 containing the first agent and the second agent and the compositions of Comparative Example 1 including the second agent were prepared, respectively.

Component (% by weight) Example
One Example
2 Example
3 Example
4 Example
5 Comparative Example
One My
One
My Oligopeptides
(Average molecular weight about 500 Daltons) 10 10 10 10 10 10 Distilled water 90 90 90 90 90 90 My
2
My 1-ethyl-3- (3-dimethylamino
Carbodiimide
[1-ethyl-3- (3-dimethyl
aminopropyl) carbodiimide] 5 - - - - - Lauric acid N-hydroxysuccinate
Imide ester
(lauric acid N-hydroxy
succinimide ester) - 5 - - - - Sulfo N-hydroxy
Succinimide
Sulfo N-hydroxy
succinimide) - - 5 - - - Pyridyldisulfide
(pyridyldisulfide) - - - 5 - - Maleimide - - - - 5 - Distilled water 95 95 95 95 95 100

Test Example  1: hair The tensile strength  Rate of change

Six hairdressers (length 12 cm, weight 3 g) made of damaged hair were prepared by bleaching twice in total, and tensile strength (unit cN, 1gf = 0.98 cN) for 100 hairs in each hairtress was prepared. ) Was calculated and the average value was calculated as the reference value. At this time, the tensile strength measuring device of DIASTRON company was used for the tensile strength measurement.

Subsequently, the hairtress was dipped for 10 minutes in the first agent of the compositions according to Examples 1 to 5 and Comparative Example 1, and then washed in running water for 30 seconds. Then, except for Comparative Example 1, after dipping for 10 minutes in the second agent of the composition of Examples 1 to 5 and washed with running water for 30 seconds, the hair was dried for 24 hours at room temperature (about 25 ℃). After calculating the average value of the tensile strength for the hair of 100 strands in each hairdressing treated as above, the results are shown in Table 2 below.

Tensile strength (cN) Example 1 Example 2 Example 3 Example 4 Example 5 Comparative Example 1 Before processing 142 139 141 143 139 142 After processing 165 167 167 156 157 149 increase + 23 + 28 + 26 + 13 + 18 + 7

Test Example  2: evaluation of surface change of hair

A total of 6 hairtresses (length 12 cm, weight 3 g) made of hair in a damaged state by bleaching a total of two were prepared and treated with the compositions of Examples and Comparative Examples in the same manner and under the same conditions as the tensile strength change rate measuring method. .

The hairdresses treated as described above were subjected to sensory evaluation on the luster, softness and smoothness of the hairless hairs of 20 women who had experience in sensory evaluation of hair products. At this time, the evaluation scale was given 1 point in the case of bad, 2 points in the case of bad, 3 points in the case of normal, 4 points in the case of good, 5 points in the case of very good, the average value of the evaluation results are shown in Table 3 below. .

Evaluation items Example 1 Example 2 Example 3 Example 4 Example 5 Comparative Example 1 burnish 4.1 3.9 4.0 3.7 3.8 3.0 Softness 4.0 4.0 4.1 3.9 3.8 3.1 lubricity 3.9 3.8 3.8 3.8 3.9 2.7

As can be seen from the results of Table 2 and Table 3, when treated with the composition according to Examples 1 to 5, compared to Comparative Example 1 treated with only the peptide, the tensile strength increase rate of the hair appears higher, damaged hair It was confirmed that the repair and reinforcement effect for the excellent. In addition, when treated with the composition according to Examples 1 to 5 it was also shown that the sensory evaluation results are superior to Comparative Example 1.

When the treatment of the compositions of Examples 4 and 5 of the above results was somewhat lower than in the case of Examples 1 to 3, which is indicated by the relatively low reactivity of the active ingredient due to the low content of cysteine present in the hair In this case, it was confirmed that the present invention can exhibit an excellent effect as compared with the case of Comparative Example 1.

Claims (9)

For hair comprising at least one compound selected from the group consisting of carbodiimide compounds, fatty acid N-hydroxysuccinimide esters, sulfo N-hydroxysuccinimides, pyridyldisulfide compounds, and maleimide compounds Cosmetic composition.
The method of claim 1,
The carbodiimide-based compound is a hair cosmetic composition is a compound represented by the following formula (1):
[Formula 1]

In Formula 1, R ¹ and R ² are each independently a linear or branched hydrocarbon having 1 to 22 carbon atoms, the hydrocarbon is an olefinic or cyclic hydrocarbon, or an alkylquaternized cation form at the end of the hydrocarbon. It is a functional group containing a nitrogen atom.
The method of claim 1,
The fatty acid N-hydroxysuccinimide ester is a hair cosmetic composition which is a compound represented by the following Formula 2:
(2)

In Formula 2, R ³ is a linear or branched hydrocarbon having 1 to 22 carbon atoms, and the hydrocarbon is an olefinic or cyclic hydrocarbon.
The method of claim 1,
The sulfo N-hydroxysuccinimide is a hair cosmetic composition which is a compound represented by the following formula (3).
(3)

The method of claim 1,
The pyridyl disulfide compound is a hair cosmetic composition is a compound represented by the following formula (4):
[Chemical Formula 4]

In Formula 4, R ⁴ is hydrogen, or a straight or branched hydrocarbon having 1 to 22 carbon atoms, or a pyridyl group; The hydrocarbon is an olefinic or cyclic hydrocarbon.
The method of claim 1,
The maleimide compound is a hair cosmetic composition is a compound represented by the following formula (5):
[Chemical Formula 5]

In Formula 5, R ⁵ is hydrogen, or a linear or branched hydrocarbon having 1 to 22 carbon atoms, and the hydrocarbon is an olefinic or cyclic hydrocarbon.
The method of claim 1,
A cosmetic composition for hair further comprising at least one compound selected from the group consisting of amino acids, peptides, proteins, and enzymes.
The method of claim 7, wherein
A agent comprising at least one compound selected from the group consisting of carbodiimide compounds, fatty acid N-hydroxysuccinimide esters, sulfo N-hydroxysuccinimides, pyridyldisulfide compounds, and maleimide compounds 1 agent; And
A second agent comprising at least one compound selected from the group consisting of amino acids, peptides, proteins, and enzymes
Cosmetic composition for hair comprising in a separate state.
The method of claim 1,
The composition is a hair tonic, hair nourishing cosmetics, hair essence, hair serum, hair treatment, hair conditioner, hair shampoo, hair lotion, hair cream, hair styling agent, hair coloring agent, or hair bleaching agent.