KR102107778B1 - Treatment composition for improving condition of damaged hair using cystamine derivative - Google Patents

Abstract

The present invention relates to a treatment composition for repairing damaged hair using a cystamine derivative. The treatment composition for repairing damaged hair using a cystamine derivative according to the present invention includes a cystamine derivative. By providing disulfide bond materials to damaged hair due to frequent dyeing, discoloration, and perm, it is possible to prevent damage to the hair and strengthen the internal fiber tissue of the hair to restore healthy hair.

Description

TREATMENT COMPOSITION FOR IMPROVING CONDITION OF DAMAGED HAIR USING CYSTAMINE DERIVATIVE}

The present invention relates to a treatment composition for recovering damaged hair using a cystamine derivative, and more specifically, to prevent damage to hair by providing disulfide-binding material of damaged hair due to frequent dyeing, discoloration, and perm treatment It relates to a treatment composition for recovering damaged hair using a cystamine derivative capable of strengthening the internal fiber tissue of the hair and restoring it to healthy hair.

Caring for health and beauty in humanity is a means of satisfying oneself and showing off to others. As life becomes relaxed, people spare no effort, time, and investment in becoming healthy and beautiful, and as the culture level improves, the beauty of the hair or the whole body is considered as important as the facial makeup.

However, this high interest in cosmetology has led to excessive hair cosmetic procedures such as perm, hair dryer, hair dyeing, and nail polish coating, which has also caused adverse effects such as physical and chemical damage to hair and skin.

Recently, as discoloration, dyeing, and heat pumps are popular, damaged hair is rapidly increasing, and once damaged, it cannot be repaired. Although commercially available hair essences and hair treatments advertise as if they are capable of repairing damaged hair, they only feel as if consumers have temporarily recovered with products using silicone and surfactant.

In addition, when washing with shampoo, all the nutrients, sebum, and moisturizing ingredients that should naturally exist in the scalp and hair tend to be removed, and further, there is a side effect that causes scalp and hair to become dry, rough, or even itchy. It is necessary to supplement this.

In general, hair is composed of a protein called keratin, and specifically, hair is a keratin protein containing 14-18% of cysteine among 18 amino acids. These keratin proteins are very strong proteins under mild conditions such as water or neutral solvents, but can be easily damaged by physicochemical treatments on hair, such as combing, dry heat, dyeing, and perm, which occur in everyday life.

In addition, in recent years, hair is damaged by various factors such as physical perm, dyeing, and other physical, chemical, or environmental factors, and the protein inside the hair elutes and becomes porous, resulting in coarse hair and loss of softness, softness and softness effects, and frictional force. There is a problem in that the hair is difficult to clean and the hair is easily cut off or the ends are cracked, and the hair is thinned and loses elasticity, resulting in loss of volume due to loss of life.

In order to solve these problems, there has been continuous research on a composition for hair to improve the softness of the hair during or after washing and to recover or strengthen damaged hair. As a result, various methods have been tried and developed to provide a strong and lasting hair conditioning effect.

For example, Korean Patent Publication No. 10-2007-0038509 discloses a cosmetic agent containing amino, amino acid or peptide conjugates of retinoic acid to prevent / treat the symptoms related to skin aging, but its effect is by washing. The disadvantage is that it falls significantly and is not persistent. U.S. Patent No. 5490980 uses a transglutaminase that forms an isopeptide bond between lysine and glutamine among amino acids constituting human protein components such as hair, skin, nails, etc., which is useful for hair, skin, and nails, Disclosed is a method for use as a means for delivering various effective substances such as antibacterial, dye, and fragrance, and Japanese Patent Publication No. 35,715,15 is a peptide having a molecular weight of 203 or higher, including transglutamine residues and / or glutamine residues, and transglutaminase and Disclosed is a hair treatment agent containing a compound having a primary amine structure of a specific formula.

However, although the enzyme used in the above inventions, transglutaminease is an enzyme having a large molecule of about 38 KDa in molecular weight, it can easily act on the surface of the hair, but actually acts on the damaged part of the inside of the hair that needs structural strengthening. The disadvantage of this difficulty is that its effectiveness is very limited.

Therefore, there is an urgent need to study a treatment composition for restoring damaged hair that can restore damaged hair to its original healthy state by various factors such as physical, chemical or environmental factors.

Domestic registration patent No. 10-1294245 (registered on August 01, 2013) Korean Patent Publication No. 10-2018-0127558 (released on November 28, 2018) Domestic registration patent No. 10-1800681 (registered on November 17, 2017)

The present invention provides a disulfide-binding material of damaged hair due to frequent dyeing, discoloration, and perm treatment, thereby preventing cystamine derivatives that can prevent damage to the hair and strengthen the internal fiber tissue of the hair to restore healthy hair. It is to provide a treatment composition for recovery of damaged hair.

Various problems to be solved by the present invention are not limited to the problems mentioned above, and other problems not mentioned will be clearly understood by those skilled in the art from the following description.

Treatment composition for recovering damaged hair using a cystamine derivative according to the present invention includes a cystamine derivative.

The cystamine derivative may be any one selected from cystamine dimaleate, cystamine dicarbocysteinate, or cystamine diglutamate.

The cystamine dimaleate contains 5 to 15% by weight of the total content of the treatment composition, and cystamine dicarbocysteinate contains 25 to 35% by weight, cystamine diglutamate (Cystamine diglutamate) may include 25 to 35% by weight.

In addition to the cystamine derivative, polyquaternium-10, water-soluble silicone, phenoxy ethanol, fragrance and purified water may be further included.

Specific details of other embodiments are included in the detailed description.

The treatment composition for recovering damaged hair using a cystamine derivative according to the present invention can prevent damage to the hair and provide internal fibers of the hair by imparting disulfide-binding material of damaged hair due to frequent dyeing, discoloration, and perm treatment Tissues can be strengthened to restore healthy hair.

It will be fully understood that embodiments of the technical idea of the present invention can provide various effects not specifically mentioned.

1 is a view for briefly explaining the principle of the treatment composition for restoring damaged hair using a cystamine derivative according to the present invention.

Advantages and features of the present invention, and methods for achieving them will be clarified with reference to embodiments described below in detail. However, the present invention is not limited to the embodiments described herein and may be embodied in other forms. Rather, the embodiments introduced herein are provided to ensure that the disclosed contents are thorough and complete and that the spirit of the present invention is sufficiently conveyed to those skilled in the art.

The terms used in this application are only used to describe specific embodiments, and are not intended to limit the present invention. Singular expressions include plural expressions unless the context clearly indicates otherwise.

Unless defined otherwise, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person skilled in the art to which the present invention pertains. Terms such as those defined in a commonly used dictionary should be interpreted as having meanings consistent with meanings in the context of related technologies, and should not be interpreted as ideal or excessively formal meanings unless explicitly defined in the present application. Does not.

Hereinafter, a treatment composition for restoring damaged hair using a cystamine derivative according to the present invention will be described in detail with reference to the accompanying drawings.

The treatment composition for recovering damaged hair using a cystamine derivative according to the present invention can prevent damage to the hair and provide internal fibers of the hair by imparting disulfide-binding material of damaged hair due to frequent dyeing, discoloration, and perm treatment Tissues can be strengthened to restore healthy hair.

That is, in general, due to frequent dyeing, discoloration, and perm treatment, the disulfide bond (-SS-) of the hair is cut to damage the hair, and the thiol (-SH) residue increases in the damaged hair. The composition for improving damaged hair according to the present invention can restore damaged hair by restoring disulfide bonds of damaged hair as described above.

The treatment composition for restoring damaged hair according to the present invention includes a cystamine derivative (CYSTAMINE DERIVATIVE).

As the cystamine derivative, any one selected from cystamine dimaleate, cystamine dicarbocysteinate, or cystamine diglutamate may be used.

In addition, in the present invention, the cystamine dimaleate (Cystamine dimaleate) contains 5 to 15% by weight of the total content of the treatment composition, cystamine dicarbocysteinate (Cystamine dicarbocysteinate) contains 25 to 35% by weight, , Cystamine diglutamate may include 25 to 35% by weight.

1.Cystamine dimaleate

(1) Chemical formula: C ₁₂ H ₂₀ N ₂ O ₈ S ₂ (MW = 384.43)

(2) Appearance: Light yellow crystalline powder

(3) Structural formula:

2. Cystamine dicarbocysteinate

(1) Chemical formula: C ₁₄ H ₃₂ N ₄ O ₈ S ₄ (MW = 512.69)

(2) Appearance: Light yellow or clear liquid

(3) Structural formula:

3. Cystamine diglutamate

(1) Chemical formula: C ₁₄ H ₃₂ N ₄ O ₈ S ₂ (MW = 448.56)

(2) Appearance: Light yellow or yellow liquid

(3) Structural formula:

Hereinafter, a specific experimental example of a treatment composition for restoring damaged hair using a cystamine derivative according to the present invention will be described in more detail.

A treatment composition for recovering damaged hair was prepared to be included in the following compositional table and weight ratio.

1. Experimental Example 1 Ingredient composition table % (wt / wt) Cystamine Dimaliate 10.00 Polyquaternium-10 0.50 Water soluble silicone 0.50 Phenoxy ethanol 0.50 Spices 0.05 Purified water Balance Sum 100.00

2. Experimental Example 2 Ingredient composition table % (wt / wt) Cystamine dicarbosinate 30.00 Polyquaternium-10 0.50 Water soluble silicone 0.50 Phenoxy ethanol 0.50 Spices 0.05 Purified water Balance Sum 100.00

3. Experimental Example 3 Ingredient composition table % (wt / wt) Cystamine diglutamate 30.00 Polyquaternium-10 0.50 Water soluble silicone 0.50 Phenoxy ethanol 0.50 Spices 0.05 Purified water Balance Sum 100.00

4. Experimental method

After applying the appropriate amount of the treatment composition blended in the weight ratios of Experimental Examples 1, 2 and 3 to healthy hair, and allowed to stand for 10 minutes, washed with lukewarm water and dried with dry hair, and compared with untreated hair.

5. Results term Materials used Moisturizing Polish elasticity Immediately after use Unprocessed X X X Cystamine Dimaliate ▲ ● ● Cystamine dicarbosinate ● ● ▲ Cystamine diglutamate ● ● ▲ 1 week later Unprocessed X X X Cystamine Dimaliate ▲ ● ● Cystamine dicarbosinate ● ● ▲ Cystamine diglutamate ● ● ▲ 2 weeks later Unprocessed X X X Cystamine Dimaliate ▲ ▲ ● Cystamine dicarbosinate ▲ ▲ ▲ Cystamine diglutamate ▲ ▲ ▲ 3 weeks later Unprocessed X X X Cystamine Dimaliate ▲ ▲ ▲ Cystamine dicarbosinate X X X Cystamine diglutamate X X X X: Poor ▲: Normal ●: Good

In the above results, the sample hair was observed every 2 days after shampooing.

Referring to the above results, it was confirmed that the damaged hair was recovered when a cystamine derivative was added compared to the untreated hair.

In addition, it can be confirmed that the result of adding cystamine maleate is recovered by reacting the cleaved S-S- bond of the damaged hair with a double bond of maleic acid.

1 is a view for briefly explaining the principle of the treatment composition for restoring damaged hair using a cystamine derivative according to the present invention.

Referring to FIG. 1, the cystamine derivative according to the present invention was able to feel the richness of the hair by increasing the elasticity and tensile strength of the hair by adding one more -S-S- of cystamine.

In addition, cystamine dicarbosinate and cystamine diglutamate are dipeptide analogs, salt-linked with protein residues of the damaged hair, and thus have moisturizing and gloss effects.

The general damaged hair cosmetic is only a temporary effect due to silicone, surfactant, etc. immediately after use, and is immediately washed off after shampooing, but the treatment composition containing the cystamine derivative according to the present invention is restored and supplemented with damaged -SS- binding The maintenance period was about 2-3 weeks.

As described above, although a preferred embodiment of the present invention has been described, those of ordinary skill in the art to which the present invention pertains understand that the present invention can be implemented in other specific forms without changing its technical spirit or essential features. Will be able to. Therefore, it should be understood that one embodiment described above is illustrative in all respects and not limiting.

Claims (4)

Cystamine dimaleate, Cystamine dicarbocysteinate or Cystamine diglutamate.
Of the total amount of the treatment composition, the cystamine dimaleate contains 10% by weight, the cystamine dicarbocysteinate contains 30% by weight, and the cystamine diglutamate 30% by weight is included,
The cystamine dimaleate is represented by the following [Chemical Formula 1], and the cystamine dicarbocysteinate is represented by the following [Chemical Formula 2], and the cystamine diglutamate (Cystamine diglutamate) is represented by the following [Formula 3],
In addition to the cystamine derivative, polyquaternium-10, water-soluble silicone, phenoxy ethanol, perfume and purified water are further included, but among the total content of the treatment composition, the polyquaternium-10 is 0.5% by weight, the water-soluble silicone is 0.5% by weight, Phenoxy ethanol is 0.5% by weight, the fragrance is 0.05% by weight and the remaining amount of purified water Treatment composition for recovering damaged hair using a cystamine derivative.
[Formula 1]

[Formula 2]

[Formula 3]

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