KR20130041664A - 고순도 몬테루카스트 나트륨 염의 제조 방법 - Google Patents
고순도 몬테루카스트 나트륨 염의 제조 방법 Download PDFInfo
- Publication number
- KR20130041664A KR20130041664A KR1020110106064A KR20110106064A KR20130041664A KR 20130041664 A KR20130041664 A KR 20130041664A KR 1020110106064 A KR1020110106064 A KR 1020110106064A KR 20110106064 A KR20110106064 A KR 20110106064A KR 20130041664 A KR20130041664 A KR 20130041664A
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- South Korea
- Prior art keywords
- montelukast sodium
- sodium salt
- formula
- light source
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Images
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020110106064A KR20130041664A (ko) | 2011-10-17 | 2011-10-17 | 고순도 몬테루카스트 나트륨 염의 제조 방법 |
| IN2765CHN2014 IN2014CN02765A (https=) | 2011-10-17 | 2012-10-16 | |
| CN201280050929.4A CN103889957A (zh) | 2011-10-17 | 2012-10-16 | 制备高纯度孟鲁司特钠盐的方法 |
| PCT/KR2012/008411 WO2013058511A2 (ko) | 2011-10-17 | 2012-10-16 | 고순도 몬테루카스트 나트륨 염의 제조 방법 |
| JP2014535665A JP2014530234A (ja) | 2011-10-17 | 2012-10-16 | 高純度モンテルカストナトリウム塩の調製方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020110106064A KR20130041664A (ko) | 2011-10-17 | 2011-10-17 | 고순도 몬테루카스트 나트륨 염의 제조 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20130041664A true KR20130041664A (ko) | 2013-04-25 |
Family
ID=48141519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020110106064A Withdrawn KR20130041664A (ko) | 2011-10-17 | 2011-10-17 | 고순도 몬테루카스트 나트륨 염의 제조 방법 |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP2014530234A (https=) |
| KR (1) | KR20130041664A (https=) |
| CN (1) | CN103889957A (https=) |
| IN (1) | IN2014CN02765A (https=) |
| WO (1) | WO2013058511A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016020321A (ja) * | 2014-07-16 | 2016-02-04 | 大日本印刷株式会社 | モンテルカストまたはその塩の製造方法 |
| US12233055B2 (en) | 2020-02-03 | 2025-02-25 | Taro Pharmaceutical Industries Ltd. | Topical Montelukast formulations |
| CA3166799A1 (en) * | 2020-02-03 | 2021-08-12 | Vered Rosenberger | Topical montelukast formulations |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7528254B2 (en) * | 2006-02-27 | 2009-05-05 | Chemagis Ltd. | Process for preparing montelukast and salts thereof |
| US7700776B2 (en) * | 2006-10-24 | 2010-04-20 | Formosa Laboratories, Inc. | Compounds and preparation for montelukast sodium |
| US8115004B2 (en) * | 2006-11-20 | 2012-02-14 | Msn Laboratories Limited | Process for pure montelukast sodium through pure intermediates as well as amine salts |
| PL205444B1 (pl) * | 2007-05-02 | 2010-04-30 | Zak & Lstrok Ady Farmaceutyczn | Sposób wytwarzania soli sodowej kwasu 1-(((1(R)-(3-(2-(7--chloro-2- chinolinylo)-etenylo)fenylo)-3-(2-(1-hydroksy-1- metyloetylo)fenylo)propylo)sulfanylo)metylo)-cyklopropanooctowego |
| CN101323589B (zh) * | 2008-03-06 | 2010-10-06 | 台耀化学股份有限公司 | 化合物及孟鲁司特钠的制备方法 |
| WO2009117381A2 (en) * | 2008-03-17 | 2009-09-24 | Dr. Reddy's Laboratories Ltd. | Preparation of montelukast and its salts |
| KR101123292B1 (ko) * | 2008-09-26 | 2012-03-19 | 주식회사 엘지생명과학 | 몬테루카스트 나트륨염의 제조방법 |
| KR100990046B1 (ko) * | 2010-07-30 | 2010-10-26 | 동국제약 주식회사 | 신규한 몬테루카스트 4-할로 벤질아민염 및 이를 이용한 몬테루카스트 나트륨염의 제조방법 |
-
2011
- 2011-10-17 KR KR1020110106064A patent/KR20130041664A/ko not_active Withdrawn
-
2012
- 2012-10-16 WO PCT/KR2012/008411 patent/WO2013058511A2/ko not_active Ceased
- 2012-10-16 JP JP2014535665A patent/JP2014530234A/ja not_active Abandoned
- 2012-10-16 CN CN201280050929.4A patent/CN103889957A/zh active Pending
- 2012-10-16 IN IN2765CHN2014 patent/IN2014CN02765A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013058511A2 (ko) | 2013-04-25 |
| JP2014530234A (ja) | 2014-11-17 |
| IN2014CN02765A (https=) | 2015-07-03 |
| WO2013058511A3 (ko) | 2013-06-13 |
| CN103889957A (zh) | 2014-06-25 |
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| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 20111017 |
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| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |