KR20120042716A - 이미노슈가 및 바이러스성 질환을 치료하는 방법 - Google Patents

이미노슈가 및 바이러스성 질환을 치료하는 방법 Download PDF

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Publication number
KR20120042716A
KR20120042716A KR1020117021770A KR20117021770A KR20120042716A KR 20120042716 A KR20120042716 A KR 20120042716A KR 1020117021770 A KR1020117021770 A KR 1020117021770A KR 20117021770 A KR20117021770 A KR 20117021770A KR 20120042716 A KR20120042716 A KR 20120042716A
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substituted
dnj
unsubstituted
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dengue
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Ceased
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KR1020117021770A
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English (en)
Korean (ko)
Inventor
얼반 람스테트
브렌난 클로세
니콜 지츠만
레이몬드 에이. 드웩
테리 디. 버터스
Original Assignee
유나이티드 세러퓨틱스 코오포레이션
더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드
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Application filed by 유나이티드 세러퓨틱스 코오포레이션, 더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드 filed Critical 유나이티드 세러퓨틱스 코오포레이션
Publication of KR20120042716A publication Critical patent/KR20120042716A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
KR1020117021770A 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법 Ceased KR20120042716A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20236709P 2009-02-23 2009-02-23
US61/202,367 2009-02-23
US27225509P 2009-09-04 2009-09-04
US61/272,255 2009-09-04

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020157006783A Division KR101755133B1 (ko) 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법

Publications (1)

Publication Number Publication Date
KR20120042716A true KR20120042716A (ko) 2012-05-03

Family

ID=42634239

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KR1020117021770A Ceased KR20120042716A (ko) 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법
KR1020157006783A Expired - Fee Related KR101755133B1 (ko) 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법

Family Applications After (1)

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KR1020157006783A Expired - Fee Related KR101755133B1 (ko) 2009-02-23 2010-02-22 이미노슈가 및 바이러스성 질환을 치료하는 방법

Country Status (8)

Country Link
US (4) US8450345B2 (enExample)
EP (1) EP2398321B1 (enExample)
JP (3) JP5600329B2 (enExample)
KR (2) KR20120042716A (enExample)
CN (2) CN106420740A (enExample)
CA (1) CA2753195C (enExample)
ES (1) ES2579628T3 (enExample)
WO (1) WO2010096764A1 (enExample)

Families Citing this family (8)

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WO2013184780A1 (en) 2012-06-06 2013-12-12 Unither Virology, Llc Novel iminosugars and their applications
US9623016B2 (en) * 2013-03-15 2017-04-18 Emergent Virology Llc Antibacterial compounds
WO2015039010A2 (en) * 2013-09-16 2015-03-19 Unither Virology, Llc Deoxynojirimycin derivatives and methods of their using
WO2016073652A1 (en) 2014-11-05 2016-05-12 Unither Virology, Llc Iminosugars useful for the treatment of viral diseases
US20190282558A1 (en) * 2016-05-16 2019-09-19 Emergent Virology Llc Methods of Treating Zika Virus Infection
KR101942757B1 (ko) 2017-08-23 2019-01-28 주식회사 유앤아이미트 마이크로웨이브를 이용한 n-노닐데옥시노지리마이신의 제조방법
CN113425720A (zh) * 2020-04-03 2021-09-24 深圳前海诺贝尔奖科学家技术转移转化有限公司 亚胺糖化合物在制备抗SARS-CoV-2病毒的药物中的用途
CN119841765B (zh) * 2025-01-09 2025-10-10 中南大学 Dnj衍生物、药物组合物及其应用

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Also Published As

Publication number Publication date
JP2014237706A (ja) 2014-12-18
ES2579628T3 (es) 2016-08-12
US20170304333A1 (en) 2017-10-26
US20100222383A1 (en) 2010-09-02
US20130237567A1 (en) 2013-09-12
JP2016175937A (ja) 2016-10-06
US20150224128A1 (en) 2015-08-13
JP2012518649A (ja) 2012-08-16
EP2398321B1 (en) 2015-11-25
JP5600329B2 (ja) 2014-10-01
HK1165221A1 (zh) 2012-10-05
CA2753195C (en) 2015-06-02
EP2398321A4 (en) 2012-01-04
CN102655746A (zh) 2012-09-05
CN102655746B (zh) 2016-08-03
EP2398321A1 (en) 2011-12-28
WO2010096764A1 (en) 2010-08-26
US9943532B2 (en) 2018-04-17
CN106420740A (zh) 2017-02-22
KR20150038684A (ko) 2015-04-08
US8450345B2 (en) 2013-05-28
US9579334B2 (en) 2017-02-28
JP5940607B2 (ja) 2016-06-29
KR101755133B1 (ko) 2017-07-06
CA2753195A1 (en) 2010-08-26
US9044470B2 (en) 2015-06-02

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