CN106420740A - 亚氨基糖以及治疗病毒性疾病的方法 - Google Patents
亚氨基糖以及治疗病毒性疾病的方法 Download PDFInfo
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- JRKICGRDRMAZLK-UHFFFAOYSA-L peroxydisulfate Chemical compound [O-]S(=O)(=O)OOS([O-])(=O)=O JRKICGRDRMAZLK-UHFFFAOYSA-L 0.000 description 1
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- OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 description 1
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
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| US27225509P | 2009-09-04 | 2009-09-04 | |
| US61/272,255 | 2009-09-04 | ||
| CN201080017591.3A CN102655746B (zh) | 2009-02-23 | 2010-02-22 | 亚氨基糖以及治疗病毒性疾病的方法 |
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| CN201080017591.3A Division CN102655746B (zh) | 2009-02-23 | 2010-02-22 | 亚氨基糖以及治疗病毒性疾病的方法 |
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| CN201080017591.3A Expired - Fee Related CN102655746B (zh) | 2009-02-23 | 2010-02-22 | 亚氨基糖以及治疗病毒性疾病的方法 |
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| CN201080017591.3A Expired - Fee Related CN102655746B (zh) | 2009-02-23 | 2010-02-22 | 亚氨基糖以及治疗病毒性疾病的方法 |
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| JP (3) | JP5600329B2 (enExample) |
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| CN (2) | CN106420740A (enExample) |
| CA (1) | CA2753195C (enExample) |
| ES (1) | ES2579628T3 (enExample) |
| WO (1) | WO2010096764A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013184780A1 (en) | 2012-06-06 | 2013-12-12 | Unither Virology, Llc | Novel iminosugars and their applications |
| US9623016B2 (en) * | 2013-03-15 | 2017-04-18 | Emergent Virology Llc | Antibacterial compounds |
| WO2015039010A2 (en) * | 2013-09-16 | 2015-03-19 | Unither Virology, Llc | Deoxynojirimycin derivatives and methods of their using |
| WO2016073652A1 (en) | 2014-11-05 | 2016-05-12 | Unither Virology, Llc | Iminosugars useful for the treatment of viral diseases |
| US20190282558A1 (en) * | 2016-05-16 | 2019-09-19 | Emergent Virology Llc | Methods of Treating Zika Virus Infection |
| KR101942757B1 (ko) | 2017-08-23 | 2019-01-28 | 주식회사 유앤아이미트 | 마이크로웨이브를 이용한 n-노닐데옥시노지리마이신의 제조방법 |
| CN113425720A (zh) * | 2020-04-03 | 2021-09-24 | 深圳前海诺贝尔奖科学家技术转移转化有限公司 | 亚胺糖化合物在制备抗SARS-CoV-2病毒的药物中的用途 |
| CN119841765B (zh) * | 2025-01-09 | 2025-10-10 | 中南大学 | Dnj衍生物、药物组合物及其应用 |
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| DE2834122A1 (de) * | 1978-08-03 | 1980-02-14 | Bayer Ag | Verfahren zur herstellung von 6-amino-6-desoxy-l-sorbose |
| DE2839309A1 (de) * | 1978-09-09 | 1980-03-27 | Bayer Ag | 3,4,5-trihydroxypiperidin-derivate |
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| DE3611841A1 (de) * | 1986-04-09 | 1987-10-15 | Bayer Ag | Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten |
| US5103008A (en) * | 1989-08-17 | 1992-04-07 | Monsanto Company | Compound, N-butyl-deoxynojirimycin-6-phosphate |
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| KR20120081990A (ko) | 2009-09-04 | 2012-07-20 | 더 챈슬러 마스터즈 앤드 스칼라스 오브 더 유니버시티 오브 옥스포드 | 이미노당 및 필로바이러스 질환의 치료 방법 |
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| JP2014237706A (ja) | 2014-12-18 |
| ES2579628T3 (es) | 2016-08-12 |
| US20170304333A1 (en) | 2017-10-26 |
| US20100222383A1 (en) | 2010-09-02 |
| US20130237567A1 (en) | 2013-09-12 |
| JP2016175937A (ja) | 2016-10-06 |
| US20150224128A1 (en) | 2015-08-13 |
| JP2012518649A (ja) | 2012-08-16 |
| EP2398321B1 (en) | 2015-11-25 |
| JP5600329B2 (ja) | 2014-10-01 |
| HK1165221A1 (zh) | 2012-10-05 |
| CA2753195C (en) | 2015-06-02 |
| EP2398321A4 (en) | 2012-01-04 |
| CN102655746A (zh) | 2012-09-05 |
| CN102655746B (zh) | 2016-08-03 |
| EP2398321A1 (en) | 2011-12-28 |
| WO2010096764A1 (en) | 2010-08-26 |
| US9943532B2 (en) | 2018-04-17 |
| KR20120042716A (ko) | 2012-05-03 |
| KR20150038684A (ko) | 2015-04-08 |
| US8450345B2 (en) | 2013-05-28 |
| US9579334B2 (en) | 2017-02-28 |
| JP5940607B2 (ja) | 2016-06-29 |
| KR101755133B1 (ko) | 2017-07-06 |
| CA2753195A1 (en) | 2010-08-26 |
| US9044470B2 (en) | 2015-06-02 |
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