KR20120014202A - ５-원 헤테로시클릭 화합물 시클로펜타［ｃ］피롤릴알킬카르바메이트 유도체, 그의 제조법 및 그의 치료 용도 - Google Patents

５-원 헤테로시클릭 화합물 시클로펜타［ｃ］피롤릴알킬카르바메이트 유도체, 그의 제조법 및 그의 치료 용도 Download PDF

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KR20120014202A
KR20120014202A KR1020117029576A KR20117029576A KR20120014202A KR 20120014202 A KR20120014202 A KR 20120014202A KR 1020117029576 A KR1020117029576 A KR 1020117029576A KR 20117029576 A KR20117029576 A KR 20117029576A KR 20120014202 A KR20120014202 A KR 20120014202A
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South Korea
Prior art keywords
formula
methyl
group
carbamate
compound
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KR1020117029576A
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English (en)
Korean (ko)
Inventor
아메드 아부압델라
오드 파욜
알리스테어 로쉐드
무라드 사디
쥴리에 바쉬
필립 예쉬
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사노피
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Publication of KR20120014202A publication Critical patent/KR20120014202A/ko

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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
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    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

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KR1020117029576A 2009-05-12 2010-05-11 ５-원 헤테로시클릭 화합물 시클로펜타［ｃ］피롤릴알킬카르바메이트 유도체, 그의 제조법 및 그의 치료 용도 KR20120014202A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0902267 2009-05-12
FR0902267A FR2945533B1 (fr) 2009-05-12 2009-05-12 Derives de cyclopenta°c!pyrrolyl-alkylcarbamates d'heterocycles a 5 chainons, leur preparation et leur application en therapeutique

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KR20120014202A true KR20120014202A (ko) 2012-02-16

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KR1020117029576A KR20120014202A (ko) 2009-05-12 2010-05-11 ５-원 헤테로시클릭 화합물 시클로펜타［ｃ］피롤릴알킬카르바메이트 유도체, 그의 제조법 및 그의 치료 용도

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Country Link
US (1) US8865738B2 (ja)
EP (1) EP2429998B1 (ja)
JP (1) JP5812985B2 (ja)
KR (1) KR20120014202A (ja)
CN (1) CN102459189B (ja)
AR (1) AR076561A1 (ja)
AU (1) AU2010247212B2 (ja)
BR (1) BRPI1014269A2 (ja)
CA (1) CA2761658C (ja)
CO (1) CO6460742A2 (ja)
EA (1) EA201171385A1 (ja)
FR (1) FR2945533B1 (ja)
IL (1) IL216228A0 (ja)
MA (1) MA33352B1 (ja)
MX (1) MX2011012057A (ja)
SG (1) SG176014A1 (ja)
TN (1) TN2011000550A1 (ja)
TW (1) TW201100413A (ja)
UY (1) UY32632A (ja)
WO (1) WO2010130943A1 (ja)

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WO2011085216A2 (en) 2010-01-08 2011-07-14 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating parkinson's disease and restless legs syndrome
WO2011123719A2 (en) 2010-03-31 2011-10-06 Ironwood Pharmaceuticals, Inc. Use of faah inhibitors for treating abdominal, visceral and pelvic pain
RU2015111206A (ru) * 2012-08-30 2016-10-20 Ниппон Синяку Ко., Лтд. Пиридиновое производное и лекарственное средство
ITMI20131180A1 (it) * 2013-07-15 2015-01-16 Fond Istituto Italiano Di Tecnologia O-alchil triazolil carbammati come inibitori di idrolasi delle ammidi degli acidi grassi (faah)
WO2015048507A1 (en) 2013-09-26 2015-04-02 Mnemosyne Pharmaceuticals, Inc. Selective octahydro-cyclopenta[c] pyrrole negative modulators of nr2b
JO3579B1 (ar) 2014-09-26 2020-07-05 Luc Therapeutics Inc مُعدِلات تفاغرية سالبة لمستقبل nr2b من المركب n-ألكيل أريل-5-أوكسي أريل-ثامن هيدرو-خماسي الحلقة [c] بيرول
MA50245A (fr) * 2017-09-11 2020-07-22 Krouzon Pharmaceuticals Inc Inhibiteurs allostériques octahydrocyclopenta[c]pyrrole de shp2
EP3686196B1 (en) * 2017-09-20 2024-06-12 Hangzhou Innogate Pharma Co., Ltd. Polycyclic compound acting as ido inhibitor and/or ido-hdac dual inhibitor
EP3856735B1 (en) * 2018-10-05 2023-09-06 New York University Fused bicyclic heterocycles as therapeutic agents

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FR2816938B1 (fr) 2000-11-22 2003-01-03 Sanofi Synthelabo Derives de 3-aroylindole, leur procede de preparation et les compositions pharmaceutiques en contenant
US7247628B2 (en) * 2002-12-12 2007-07-24 Pfizer, Inc. Cannabinoid receptor ligands and uses thereof
FR2864080B1 (fr) * 2003-12-23 2006-02-03 Sanofi Synthelabo Derives de 1-piperazine-et-1-homopiperazine-carboxylates, leur preparation et leur application en therapeutique
FR2866884B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
FR2866888B1 (fr) * 2004-02-26 2006-05-05 Sanofi Synthelabo Derives de alkylpiperazine- et alkylhomopiperazine- carboxylates, leur preparation et leur application en therapeutique
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WO2010130943A1 (fr) 2010-11-18
EP2429998B1 (fr) 2013-11-27
FR2945533B1 (fr) 2011-05-27
BRPI1014269A2 (pt) 2016-04-05
AU2010247212A1 (en) 2011-12-08
SG176014A1 (en) 2011-12-29
CA2761658C (fr) 2017-04-11
TW201100413A (en) 2011-01-01
US20120136026A1 (en) 2012-05-31
JP5812985B2 (ja) 2015-11-17
US8865738B2 (en) 2014-10-21
CN102459189B (zh) 2014-11-05
FR2945533A1 (fr) 2010-11-19
JP2012526782A (ja) 2012-11-01
EP2429998A1 (fr) 2012-03-21
TN2011000550A1 (fr) 2013-05-24
MA33352B1 (fr) 2012-06-01
CA2761658A1 (fr) 2010-11-18
CN102459189A (zh) 2012-05-16
UY32632A (es) 2010-12-31
MX2011012057A (es) 2012-02-28
CO6460742A2 (es) 2012-06-15
EA201171385A1 (ru) 2012-05-30
IL216228A0 (en) 2012-01-31
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