KR20110118497A - Cosmetic composition for moisturizing and elasiticity of skin containing the laminaria japonica extract, undaria pinnatifida extract and plantago asiatica seed extract - Google Patents

Abstract

The present invention relates to a cosmetic composition containing the kelp extract, seaweed extract and chason extract as an active ingredient. More specifically, the present invention relates to a cosmetic composition containing kelp extract, wakame extract and cha cha extract as an active ingredient to improve the moisturizing power of the skin and at the same time improve the skin elasticity.

Description

Cosmetic composition for moisturizing and elasticity containing kelp extract, seaweed extract and chason extract {Cosmetic composition for moisturizing and elasiticity of skin containing the LAMINARIA JAPONICA extract, UNDARIA PINNATIFIDA extract and PLANTAGO ASIATICA SEED extract}

The present invention relates to a cosmetic composition containing the kelp extract, seaweed extract and chason extract as an active ingredient. More specifically, the present invention relates to a cosmetic composition containing kelp extract, wakame extract and cha cha extract as an active ingredient to improve the moisturizing power of the skin and at the same time improve the skin elasticity.

The skin is divided into three layers of epidermis, dermis, and subcutaneous fat tissue in order from the outside, and protects the body from physical and chemical stimuli from the external environment. It controls the evaporation of ~ 70% of moisture out of the body. Among them, the epidermis is divided into the stratum corneum, granule layer, polar layer, and basal layer from the outside. The stratum corneum of the epidermis contains about 10-20% of moisture and exists at the outermost part of the human body to suppress evaporation of moisture from the body. Blocks material invasion from outside ( J. Invest . Dermatol . 80 ( Suppl .), 44-49. 1983 ). The cells constituting the stratum corneum have high concentrations of natural moisturizing factor (NMF), which are water-soluble ingredients, which help the skin to show flexibility and maintain proper moisture ( J. Invest . Dermatol . 54, 24-31, 1970 ). However, due to changes in the environment or changes in life patterns, various stresses and environmental pollution caused by social life, frequent face washing due to makeup habits, and natural skin aging due to age increase, moisture in the stratum corneum decreases and the skin dries. Problems related to moisturizing the skin are becoming more and more important as phenomena such as surface roughness, skin loss, and dullness appear.

As the skin ages, the decrease in elasticity progresses due to photoaging caused by ultraviolet rays, increase in age, endogenous factors such as menopause, genetic factors, and environmental factors, resulting in decreased fibroblast division, collagen synthesis, and MMP production. Due to the increase of the elasticity of the skin is reduced. In particular, around the 40s, the balance of hormones is broken, and cell regeneration ability, collagen synthesis ability, and skin lipid generation, which play an important role in skin moisturization, are greatly reduced. As consumers' desire to look young and their expectation for cosmetics are increasing, research on cosmetics aiming at improving skin elasticity reduction is being actively conducted.

In general, cosmetics are intended to clean the body, to make themselves beautiful and attractive, and to prevent aging by protecting the skin or hair from ultraviolet rays or drying. Recently, with the development of industrial society and the increase of social activities, the self-consciousness to actively express oneself is increasing, and the desire to care for and maintain the health of one's own skin using cosmetics is increasing. Accordingly, the basic and color cosmetics of various forms and formulations have been researched and developed. Among them, cosmetics having a skin moisturizing effect and skin elasticity improving cosmetics that improve skin dryness are recognized as the most important products in various categories.

Therefore, various cosmetic raw materials are being developed in the sense of improving skin moisturizing and skin elasticity. In recent years, the use of animal raw materials has been drastically due to declining consumer's preference for animal raw materials and ripples such as mad cow disease. Reduced and natural plant-derived materials are in the spotlight. In addition, consumers are also developing plant extracts that can have multi-functions by increasing their preference for multi-functional cosmetics, for example, moisturizers and cosmetics that have elasticity-enhancing effects as an additional function. It became a very urgent and important matter.

As a result of repeated studies, the present inventors have found that the components of kelp extract, seaweed extract and chasen extract have improved the skin's moisturizing ability and increase the elasticity of the skin, thereby completing the present invention.

Accordingly, it is an object of the present invention to provide a skin cosmetic composition having excellent moisturizing power.

Another object of the present invention to provide a skin cosmetic composition for improving the elasticity of the skin.

In order to achieve the above object, the present invention provides a cosmetic composition for skin moisturizing or skin elasticity containing kelp extract, seaweed extract and chaja extract as an active ingredient.

Skin cosmetic composition of the present invention contains the kelp extract, seaweed extract and chasen extract to increase the skin moisturizing power, and also excellent skin elasticity improvement effect.

1 is a graph showing changes in skin water volume before and after application of Example 1 and Comparative Example 1. FIG.
2 is a graph showing changes in skin elasticity before and after application of Example 1 and Comparative Example 1. FIG.
Figure 3 is a photograph showing the shape change of the artificial dermis before and after the application of Example 1 and Comparative Example 1.
4 is a graph showing changes in the water evaporation amount of artificial dermis before and after application of Example 1 and Comparative Example 1. FIG.
FIG. 5 shows changes in occludin expression of tight junctions after application of Example 1 and Comparative Example 1. FIG.

The cosmetic composition of the present invention contains kelp extract, wakame extract and chason extract.

In particular, the cosmetic composition of the present invention, it is preferable to use sesame seaweed extract, seaweed seaweed extract and chason extract.

Chamdashima used in the present invention refers to the kelp (Laminaria japonica) belonging to the brown seaweed kelp family, in the Oriental medicine system is dried frond and used as a herbal medicine called balun (昆布) and its taste is salty and cold and works with the kidneys and liver. . Eliminate sputum and blood and make urine come out so it is used to remove cough, asthma and sea water. In addition, it contains a large amount of minerals such as iodine and potassium, and has an effect of promoting metabolism. In the <Communication>, it says, "It controls the acid, calms the boil, and controls the hump of the hump to soften the hard."

The kelp extract used in the present invention is accurately weighed 50 g of lyophilized kelp, and then extracted by organic cold at room temperature for 48 hours, and then completely evaporated by using an evaporator. After concentration it was used as a sample without further manipulation. In this case, the organic solvent may be one or more selected from the group consisting of ethanol, methanol, butanol, ether, ethyl acetate and chloroform, or a mixed solvent of these organic solvents and water may be used. In addition, the process of obtaining the extract is not limited to the above.

The skin cosmetic composition of the present invention contains the kelp extract in an amount of 0.001 to 10% by weight based on the total weight of the composition. This is because a pronounced effect can not be expected at less than 0.001% by weight, and when it exceeds 10% by weight, no apparent effect increases with increasing content.

Seaweed seaweed refers to seaweed (undaria pinnatifida), a year-old seaweed with brown seaweed, and is commonly referred to as haechae, or persimmon, chaechae, and haedae. In <Communication Bogam>, “Haechae is cold, salty, and not poisonous. Efficacy is to get rid of stuffiness with fever, to treat the clumps and to urinate well. ”

Wakame extract used in the present invention is accurately weighed 50g of lyophilized wakame seaweed, then extracted by cold at room temperature for 48 hours with an organic solvent, and then completely evaporated organic solvent used for extraction using an evaporator (evaporator) After concentration it was used as a sample without further manipulation. In this case, the organic solvent may be one or more selected from the group consisting of ethanol, methanol, butanol, ether, ethyl acetate and chloroform, or a mixed solvent of these organic solvents and water may be used. In addition, the process of obtaining the extract is not limited to the above.

The external preparation for skin composition of the present invention contains the above seaweed extract in an amount of 0.001 to 10% by weight based on the total weight of the composition. This is because a pronounced effect can not be expected at less than 0.001% by weight, and when it exceeds 10% by weight, no apparent effect increases with increasing content.

Chason refers to the seeds of Plantago asiatica L., a plant belonging to the Plantaginaceae, and is the oriental medicine's efficacy of diuresis, clear heat, nominal and expectorant. There is, urinary incontinence, lobster, hematuria, sea water, the purpose (目赤) is mainly used to treat. According to <Agreement Bogam>, "Charger mainly treats the weakness of urine and does not come out well, controls five kinds of gonorrhea, makes the urine clogged and pretends, makes the water excrete well, brightens the eyes, Eliminates congestion, and heals the soy sauce. ” Therefore, the tea can improve the symptoms of swelling due to toxic edema.

Next, the process of obtaining the cha-cha extract used in the present invention is as follows. Accurately weigh 50 grams of the electrons, extract them with organic solvents at room temperature and cold for 48 hours, and then use an evaporator to completely evaporate and concentrate the organic solvents used for extraction. Used. In this case, the organic solvent may be one or more selected from the group consisting of ethanol, methanol, butanol, ether, ethyl acetate and chloroform, or a mixed solvent of these organic solvents and water may be used. In addition, the process of obtaining the extract is not limited to the above.

The external preparation composition for skin of the present invention contains the above-mentioned tea extract in an amount of 0.001 to 10% by weight based on the total weight of the composition. This is because a pronounced effect cannot be expected at less than 0.001% by weight, and if it exceeds 10% by weight, no apparent effect increases with increasing content.

The external preparation composition for skin according to the present invention contains a cosmetically and dermatologically acceptable medium and / or base. These are all formulations suitable for topical application, for example emulsions, suspensions, microemulsions, microcapsules, microgranules or ionic (liposomes) obtained by dispersing an oil phase in a solution, gel, solid or pasty anhydrous product, aqueous phase, and / or It may be provided in the form of a nonionic vesicle dispersant or in the form of a cream, skin, lotion, powder, ointment, spray or cone stick. These compositions can be prepared according to conventional methods in the art. In addition, the topical skin composition according to the present invention may be used in the form of a foam or in the form of an aerosol composition further containing a compressed propellant.

The external preparation composition for skin according to the present invention is a fatty substance, an organic solvent, a dissolving agent, a thickening agent and a gelling agent, an emollient, an antioxidant, a suspending agent, a stabilizer, a blowing agent, a fragrance, a surfactant, water, an ionic or nonionic emulsifier, Cosmetics or skin such as fillers, metal ion sequestrants and chelating agents, preservatives, vitamins, blockers, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic actives, lipid vesicles or any other ingredients commonly used in cosmetics And auxiliaries commonly used in the scientific field. These adjuvants are introduced in amounts generally used in the cosmetic or dermatological fields.

Hereinafter, although an Example and a test example are given and this invention is demonstrated in detail, this invention is not limited only to these examples.

Preparation Example 1 Preparation of Chada Shima Extract

Accurately weigh 50 g of lyophilized sea bream seaweed, extract it with 70% ethanol for 48 hours at room temperature, and then completely evaporate and concentrate the ethanol used for extraction using an evaporator. Prepared.

Preparation Example 2 Preparation of Seaweed Extract

Accurately weigh 50 g of lyophilized seaweed seaweed, extract with 70% ethanol for 48 hours at room temperature, and then completely evaporate and concentrate the ethanol used for extraction using an evaporator to prepare a seaweed seaweed extract. It was.

Preparation Example 3 Preparation of Chason Extract

Accurately weigh 50 g of the chager, and then extract it by using a 70% ethanol for about 48 hours at room temperature, and then completely evaporate and concentrate the ethanol used for extraction by using an evaporator to prepare a true seaweed extract.

<Example 1 and Comparative Example 1>

To prepare a cream formulation of Example 1 and Comparative Example 1 in the composition of Table 1 (unit: wt%).

ingredient Example 1 Comparative Example 1 Preparation Example 1 1.0 0 Production Example 2 1.0 0 Production Example 3 1.0 0 Purified water Balance Balance glycerin 8.0 8.0 Butylene glycol 4.0 4.0 Hyaluronic acid extract 5.0 5.0 Beta Glucan 7.0 7.0 Carbomer 0.15 0.15 Caprylic / Capric Triglycerides 8.0 8.0 Squalane 5.0 5.0 Cetearyl Glucoside 1.5 1.5 Sorbitan stearate 0.4 0.4 Cetearyl Alcohol 2.0 2.0 antiseptic Quantity Quantity incense Quantity Quantity Pigment Quantity Quantity Triethanolamine 0.15 0.15

Test Example 1 Measurement of Skin Moisture Content

The subjects were selected from 30 women aged 30 years, divided into Example 1 and Comparative Example 1 and allowed to use Example 1 and Comparative Example 1 on the left and right cheeks, respectively, two weeks after the skin moisture content was measured. Specifically, after washing the face with soap for 30 subjects, the skin was adapted under constant temperature and humidity conditions (temperature 20 ± 2 ℃, relative humidity 40 ± 2%). The skin surface capacitance was measured three times using a Corneometer (CM825). The average result is shown in FIG.

As can be seen in Figure 1, after using Comparative Example 1 for 2 weeks, the moisture content of the front of the cheeks increased by 3% and the moisture content of the lower part of the cheeks, which is a particularly dry part of the face, increased by 11%, whereas after using Example 1 for 2 weeks The water content of the front of the cheeks is increased by 10% and the water content of the lower part of the cheeks is 78%, it can be seen that the skin moisture content can be significantly increased when using the embodiment according to the present invention.

Test Example 2 Measurement of Skin Elasticity Improvement

Thirty subjects of Test Example 1 measured skin elasticity after using Example 1 and Comparative Example 1 for two weeks. Specifically, after washing the face with soap for 30 subjects, the skin was adapted under constant temperature and humidity conditions (temperature 20 ± 2 ℃, relative humidity 40 ± 2%). The skin elasticity was analyzed by measuring the degree of recovery of the skin which is pulled by applying a negative pressure to the skin using a cutometer (A Cutometer MPA580). The results are shown in FIG.

As can be seen in Figure 2, after using Comparative Example 1 for two weeks skin elasticity increased by 0.1%, after using Example 1 it can be seen that the skin elasticity improved by 6.6% showed a remarkably excellent effect.

Test Example 3 In vitro Testing of Moisturizing Power

Example 1 and Comparative Example 1 were applied to artificial dermis (Dermal Equivalent) made of collagen and fibrobalst, respectively, and the shape of artificial dermis immediately after application and 5 hours after application were shown in FIG. Was measured and the result is shown in FIG.

3 and 4, Comparative Example 1 can confirm that the collagen gel shape is disturbed by evaporation of water, while Example 1 inhibits evaporation of water to maintain the original shape of the collagen gel.

In addition, the moisture evaporation amount of Comparative Example 1 and Example 1 can be confirmed that the difference between more than 10% after 5 hours.

Test Example 4 In vitro Testing of Expression of Tight Junction Proteins

Tight junction plays an important role in maintaining and strengthening the skin's barrier function. The function of this tight junction can be confirmed by occludin, a cell membrane protein that is specifically expressed in the tight junction. When the tight junction protein expression is inhibited, TEWL (transepidermal water loss) hard epidermal water loss (TEWL) greatly increases, leading to loss of water. It can be said that the relationship with.

Human-derived keratinocytes (HaCaT) were incubated on the coverslip for microscopic observation. At this time, the groups treated with Comparative Example 1 and Example 1 were cultured separately. After 24 hours, the cells were washed with PBS containing 1 mM CaCl ₂ and 1 mM MgCl ₂ and fixed with paraformaldehyde solution. After increasing the permeability of the cell membrane with 0.1% Triton X-100 solution, the primary antibody against occlusin was attached for 1 hour. After washing the cells with PBS again, the secondary antibody (Alexar fluor 488) was attached for 1 hour for fluorescence observation. The fluoridation protein expression level change was observed using a fluorescence microscope (LSM510). The results are shown in FIG.

As a result, in the human-derived keratinocytes treated with Comparative Example 1, the expression of the occlusion, a tight junction specific protein, could not be observed, but the expression of ocludin was increased in the human-derived keratinocytes treated with Example 1 Could confirm.

Claims (4)

Skin moisturizing cosmetic composition containing kelp extract, seaweed extract and chajeon extract as an active ingredient. The cosmetic composition for moisturizing skin according to claim 1, wherein the kelp extract is a real seaweed extract, and the seaweed extract is a true seaweed extract. The cosmetic composition according to claim 1, wherein the kelp extract, wakame extract and chasen extract are contained in an amount of 0.001 to 10% by weight, respectively, based on the total weight of the composition. According to claim 1, wherein the composition is a cosmetic composition, characterized in that for enhancing skin elasticity.

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