KR20110019569A - Composition of health food - Google Patents

Abstract

PURPOSE: A producing method of health promoting food using a kalopanax ricinifolium extract is provided to offer the excellent curing and prevention effect for diabetes. CONSTITUTION: A producing method of health promoting food using a kalopanax ricinifolium extract comprises a step of mixing medical herb powder and the kalopanax ricinifolium extract, and forming pills. The medical herb powder includes dried silkworm powder, rehmannia glutinosa, cornus officinalis, cuscuta japonica, rubus coreanus, torilis japonica, poria cocos, schisandra chinensis, mulberry leaves, dioscorea batatas, garlic, sea tangle, ledebouriella seseloides, lithospermum erythrorhizon, taraxacum mongolicum, and artemisiae capillaries.

Description

Health functional food composition effective in blood circulation, joint protection, cerebrovascular treatment, prevention and prevention of diabetes and preparation method thereof

The present invention relates to a healthy functional food based on the silkworm powder manufactured from the extract of silkworm powder and the bark of the bark, the subject of the present invention, more specifically 9% by weight of dried silkworm powder, 5% by weight of ripening scent, cornus oil 5 Weight%, Tosa 5% by weight, Bokbunja 6% by weight, Casualty 5% by weight, Fuling 5% by weight, Schisandra chinensis 5% by weight, Mulberry leaves 8% by weight, Acidic 5% by weight, Garlic 8% by weight, Kelp 8% by weight, Windproof 6 Blood circulation, joint protection, cerebrovascular, diabetes mellitus, characterized in that by mixing and kneading the herbal medicine powder and oak bark extract consisting of 5% by weight, 5% by weight, 7% by weight of dandelion and 8% by weight of chia seeds It relates to a healthy dietary supplement composition which is effective for treatment and prevention.

Recently, as the standard of living in Korea increases, interest in oriental medicine is increasing, and according to this trend, interest in medicinal plants is also increasing. With the improvement of the national income level and the growing interest in health and the diversification of eating habits from stocks, the growing interest in low-pollution vegetables and functional foods with excellent pharmacological functions increases the consumption of medicinal plants. have. On the other hand, functional food is being recognized as a new value for promoting the physiological activity of human beings, the meaning is changing to the concept of health functional food as a food that maintains health.

Kalpanax pictus NAKAI, also known as Eum tree, is a deciduous tree belonging to the family Elmaceae, with over 80 species and 900 species distributed worldwide. There are 20 varieties of 8 genus, 14 species, 5 varieties, and 1 species. The main distributions are Japan, Sakhalin, Okinawa and China. In Korea, it grows in the sunny area at the foot of 100 ~ 1,800m altitude of Jeollabuk-do, Gangwon-do, etc., and the area around 400-500m is the central zone. Plants of the genus Kalopanax grow wildly in our country, and are known to be found in hairy trees, sugar beetwood, and thin leafy trees. From ancient times, the bark of the moth is called Kalopanacis Cortex, and the root of the root is called thaw root, and it has been widely used as expectorant, analgesic, tonic and neurological medicine. Moreover, recently immunological and antioxidant activities have been reported. Studies on plants of the genus Kalopanax isolated hederagenin, kalotoxin, kalosaponin and kalosapogenin from the skin. Benhenic acid, palmitic acid and linoleic acid were also isolated from the seeds. Since liriodendrin (liriodendrin) and hederin (hederin) was separated, hederagenin (hederagenin) was separated from the shell. Studies on the physiological activity and its components of moths have shown that the main components of the moths include saponins (Kalopanax saponins), lignans (syringin, liriodendrin), phenols (coniferin, protocatechuic acid) and alkaloids (erykalraline). ), Amino acids, flavonoids and the like are found. The components of the oak tree can be used as a good material for the development of new medicines, and can be used as health foods.

Among the silkworms, the young awakened from the egg is the tomb, the black hairless young stool, the third sleeping silkworm, the three-year-old silkworm, the 27-day-old silkworm, and the old one to sleep. (紅 蠶), chrysalis dragon (성), adult adult (蛾), cocoon dog (), and shit was called Jasa (蠶 砂). The body is cylindrical and has three parts: head, chest, and abdomen. The body becomes 14 nodes at embryonic stage, but the 13th node becomes smaller during embryonic development, and it becomes 13 nodes because it fuses with 14th node. . Legs 3 pairs in breast segment, 4 pairs in ventral segment, with palate on dorsal side of 11th segment. There are six pairs of eyes, but they cannot visualize, and the taste and smell are done by the lower jaw beard. I don't like direct sunlight and I like the brightness of 15-30 lx. The body is frosted and covered with a soft chitin shell for a soft texture. According to the sympathy of silkworm, Yangyang (陽 事) is strong, set (泄精) and bleeding (그), stop the warming (水 臟), add a regular (精 氣) and sound (陰道) It is said that it has been used as a medicine to improve men's virility since it does not cause fatigue even after indoctrination.Since silkworms have many vitamin E ingredients, anti-aging and energetic functions are promoted by anti-oxidation function, as well as promoting energy. Men's nourishment to strengthen the sexual function, silkworm powder is effective in high blood pressure and anti-glycemic effect, and for people with chronic weakness constitution to strengthen the immune function, restore the respiratory function cold Create a constitution that does not take. In addition, it promotes pulmonary function and accelerates fatigue after severe exercise, and potassium in silkworm powder is very effective in normalizing blood pressure. It is also good for allergic dermatitis and menopausal disorders.

Silkworms on mulberry leaves have been shown to have anti-cancer effects, anti-aging, anti-palsy, anti-blood pressure and cholesterol-lowering effects, and physiological activities of diabetes treatment.

Mulberry leaves are very nutritious and contain about 20-40% crude protein when dried. There are about 25 kinds of amino acids that make up the protein of mulberry leaves, among which 3% of alanine and aspartic acid are effective in removing hangovers. The mulberry leaves are 1.2% and 0.8% of serine and tyrosine, respectively, which help to spin blood in the brain, remove cholesterol, and prevent senile dementia. Calcium contains 60 times more than cabbage, iron 160 times more than radish, phosphorus 10 times more than radish, fiber contains as much as dried radish or sweet potato. Dietary fiber contains more than half the weight of dried mulberry leaves. In addition, it is rich in vitamins A, B, C, and D. This is 6 times more calcium, 2 times iron, 13 times sodium and 1.4 times more potassium. Vitamins are slightly lower than green tea, but dietary fiber is 52% in mulberry leaves and 11% in green tea. Caffeine is not found in mulberry leaves. Mulberry leaves contain a large amount of physiologically active substances. Especially, physiologically active substances such as deoxynojirimycin (DNJ) pagomin, calistine, rutin, GABA and moracenin act to lower blood sugar and blood pressure.

Sukjihwang is the main medicine of Samul-tang (四 物 이며) and is used for symptoms such as heat resistance, dry throat, and thirst caused by the weakness of various chronic diseases. Samultang is widely used for women with excessive bleeding, weakness, and dizziness due to postpartum and menstruation. It has been effective in treating hudam since ancient times, and it was drunk as a tea, and it was used in combination with cough and asthma in Bokryeong (반 夏).

Cornus is a deciduous arborescent tree of the dogwood family. Flowers bloom before leaves in March-April and yellow and fruits ripen in August. This pulp is called cornus oil in Chinese medicine. Steamed with strong sweetness and strong acidity. Harvested after mid-October in October, meat and seeds are separated and meat is used for alcohol, tea and herbal medicine. The pulp contains glycosides such as cornin, morroniside, loganin, tannin, and saponin, and organic acids such as doju, apple, and tartaric acid. It also contains vitamin A and a large amount of sugar. Seeds contain palmitic acid, oleic acid, linoleic acid, and the like. Among the components, cornine is known to have an excitatory action of parasympathetic nerves. The efficacy of cornus is warming the waist and knees, the urine is beneficial, and the nature of the cornus is slightly warm and sour to protect the liver and sour (腎) and harden, especially strengthening the function of God is good for energy enhancement. Dongbobom is a converging tonic that reinforces the kidneys of the kidneys and enriches the male's essence to maintain energy, and is effective in maintaining pain and syringes in the lower back and knees of adult men and women. It is said to be good.

Tosa is effective for regular reinforcement, suppression of endocrine, and fundamental healing of endocrine disorders. Bokbunja usually refers to raspberries that commonly grow in Korea's mountains and mountains. White flowers bloom in May and ripen dark red in July-August. Ripes are sweet and sour. However, when used as medicine, write less picked and dried. Tastes and is warm and nonpoisonous. Energize, lighten your body, brighten your eyes, and avoid whitening your hair. Raspberries help strengthen kidneys to treat wells and dreams, and to help maintain a constant amount of urine and excretion. Therefore, it is also effective for children who pee while sleeping and adults who cannot go to the toilet and often go to the bathroom. It is a tonic remedy that is used in men's hypnosis, which has an unusually high rate of rhythm and debilitating energy. For women, it has a zest, which is widely used for infertility due to mental breakdown, and it is known as a plant that moisturizes the skin. It is effective in reducing vision and night blindness caused by nervous breakdown, and it also warms the inside to protect the liver, reduce urine, and strengthens energy and energy. It also has effects on diabetes, and it is rich in antioxidants, which clears the blood and helps the energy, makes the body lighter, and is effective in preventing adult diseases because it has excellent treatment and preventive effects on paralytic dementia and degenerative inflammatory diseases.

Casualties are perennial herbaceous plants, 30-70 cm high. Young shoots are eaten as herbs, and fruits are used as astringents, anti-inflammatory agents, and insecticides. The leaves are like palaces, flowers are white, like eggs, and they come from yellow, light and light, dry land. In May, the leaves are picked and dried in the shade. Casualties warm and heighten the kidneys and apply them to conditions such as male immoralism and female infertility. It has been used as an external medicine and ointment for anti-inflammatory or itching as it is effective for skin pruritus by treating the cold treatment of women and inhibiting the activities of influenza virus and toricomonas. In addition, casualties have a therapeutic effect on skin diseases, so it is also used as an external medicine such as skin eczema, allergic dermatitis and dermatitis. The ingredients are uniform, taste and sweet, and there is no poison, so the wife's somatic pain, the man's genitals, the wet pockets are healed, the wife's womb is warmed, the man's sound is strong, and the man's sound is satisfied. Casualties have the same effect as male hormones, acting as aphrodisiacs, and are effective in reducing sexual function, fatigue, and impotence, and have been used for a long time as a nourishing tonic food.

Bokryeong helps diuretic and digestive action, the uterus is good for the circulation center, calms the mind, if used in large quantities as an anesthetic, it lowers blood pressure, fever is functioning. The medicine is effective for nourishing the eyes and corners, ripening, branching, protecting the fragile body, and preventing and treating nocturnal enuresis and diabetes.

Schisandra chinensis from Chinese medicine, `` fruit of Schisandra chinensis '' as a medicinal herb, has the effect of helping the lungs and is used as a medicine for coughing or thirst. Schisandra chinensis lowers blood sugar levels and is effective for quenching thirst in diabetics. Sweat and diarrhea It is also used to stop. Omiza is rich in various organic acids, calcium, vitamin c, iron, manganese and phosphorus, and has been widely used for fatigue recovery and popular medicines. Schisandra has five flavors as its name suggests. The skin is sour, the flesh is sweet, the nucleus is hot and bitter, while the whole is salty and colorful. These five flavors go well with the taste as well as with the jang. The soy is sour, the lungs are spicy, and the heart is bitter. The spleen and kidney are also energized for their sweet and salty taste, respectively. The pulp of Schisandra chinensis is rich in organic acids such as malic acid and tartaric acid. Soy sauce's favorite sour taste is to 'collect and converge'. Convergence means to capture scattered energy in the center of the body. Schisandra attracts scattered energy to reinforce weakness and exert an effect on lethargy. Schisandra helps the lungs

It is also useful for coughing or sore throats. Schizophrenic taste of Schisandra chinensis is a contraction of the bronchial tuberculosis patients with chronic bronchiectasis is very good at coughing and asthma.

The constituents of kelp vary depending on the type, but are usually water 16%, protein 7%, fat 1.5%, carbohydrate 49%, and 20% of these carbohydrates are fibers, and the rest are water-soluble polysaccharides such as alginic acid, laminarin and mannite. It is also rich in vitamins, especially vitamin B2, which is higher than other seaweeds. Seaweed is also called a treasure trove of minerals.

Kelp is rich in urea. It is said that kelp is king of seaweed only by showing content of about 280 mg in 100%. Kelp is also rich in calcium. The rich ash content of kelp is an excellent alkaline food with an alkalinity of (+) 40.03. In addition, alkaline mineral calcium is more than acid inorganic phosphorus. In general, foods contain more phosphorus than calcium, and most of them lack calcium.

Therefore, kelp is a valuable food source of calcium, and if you look at its efficacy, alginic acid contained in kelp is excellent in constipation. Alginic acid, like other dietary fibers, is not absorbed by the body and is sent to the intestines. Undigested alginic acid stimulates the intestines to promote bowel movements and help defecation. When you eat kelp, drink plenty of water. Alginic acid absorbs moisture from the body and expands up to 200 times. Since the intestines move more actively with more contents, the more alginate expands, the more intestinal movement becomes. Leaving constipation for a long time can cause colon cancer. Kelp's alginic acid solves constipation and prevents colon cancer. Alginic acid, which is sent to the large intestine undigested, is mixed into the stools, which increases the amount of stools. In addition, alginic acid absorbs carcinogens and excretes them without irritating the intestinal membranes, thus preventing colon cancer or rectal cancer. The slimy component of kelp is alginic acid, which is combined with cholesterol and salt in the intestine and excreted with stools. In addition, it prevents hypertension and arteriosclerosis, directly or indirectly, by preventing blood clots or synthesis of cholesterol in the liver. Laminin, an amino acid, lowers blood pressure and prevents cholesterol from sticking to blood vessels. Potassium in kelp also releases sodium to lower blood pressure. In addition, kelp has little calories and is a good food for diabetics. Kelp's dietary fiber delays the penetration of glucose into the blood and aids in the digestion and absorption of sugar to lower blood sugar levels. Kelp is rich in minerals and is considered an alkaline food. People who eat a lot of meat tend to become acidic, but eating a lot of kelp can neutralize the acid constitution, and kelp not only contains a lot of calcium, but also has abundant magnesium, which makes calcium active. . Calcium, which is a major component of bone, is gradually lost when the meal is irregular or older. When bone density is low, osteoporosis develops, and kelp has the effect of preventing it. If you chop kelp largely, calcium is combined with alginic acid so it does not melt well. Finely chopped and chewed tightly will increase the absorption. In addition, the lack of thyroid hormones secreted by the thyroid gland in the neck area, the metabolism is slowed down, no energy and aging progresses quickly. In severe cases, it may cause goiter. Kelp contains a lot of iodine, an important component of thyroid hormones, which can help prevent thyroid disease, as well as proteins, vitamins A, D, and E that are needed for hair health, as well as iodine, zinc, sulfur, iron, and calcium. Contains many ingredients that make up. It also contains oxo, a hair growth promoter, and eating enough kelp can help prevent hair loss and keep your hair shiny.

Dandelion (Taraxacum herba) is a perennial herb belonging to the genus Asteraceae, also called Pogongyoung, and is widely distributed throughout Korea from early spring to late autumn. From ancient times, dandelions have been known to have roots, leaves, flowers,

It has been known as one of the few herbs that can medicinal all plants, such as stems. Dandelion tastes bitter, salty, and flat in nature. Dongbogam describes dandelion as a fever, detoxification, diuresis, and the most effective effect, it is used for the treatment of liver and gallbladder disease, to relieve the ulcers and to relieve inflammation or boil. ) Dandelion juice continued to darken the hair and to strengthen the stomach and bones. It is possible to use both externally and externally, and the effect is stated to be very large. In addition, according to folk remedies, dandelion has been used in tonic, antipyretic, diuretic, healthy, expectorant, antidote, etc., and is also used in the West as a drug for promoting bile secretion, antirheumatic, diuretic and the like.

Generally, wormwood is a perennial grass belonging to the Asteraceae family, and depending on its shape and fragrance, there are about 30 species in Korea alone. Mugwort is divided into edible and medicinal and is used for various purposes due to the well-known efficacy of mugwort. Mugwort is known to have antibacterial, blood coagulation, uterine contractions, bronchiectasis, fever, etc. In oriental medicine, mugwort using a lot of the benefits of the mugwort is used a lot. It is known that the wormwood is particularly good at the beach or the island, and the representative one is Sasangari wormwood on Jawoldo in Ganghwado and offshore Incheon, which is known to grow well against the sea breeze of the west coast. The wormwood is shorter than other wormwood and has a glossy leaf, rounded leaf tip, slender wormwood, and hairy hair. The main ingredients of mugwort are calcium, fiber, vitamin A, vitamin B, vitamin C, etc. The mugwort used for medicinal use is usually picked up within 5 days before and after May. The ingredients of mugwort in 100g of mugwort made by Rural Development Administration and Japan Science and Technology Agency are as follows. Water 81.4g, ash 2.0g, protein 7.7g, iron 10.9mg, fiber 3.7mg, vitamin B2 0.23mg, phosphorus 70mg, sugar 4.0g. 0.12 mg of vitamin B, 140 mg of calcium, 22 mg of vitamin C, vitamin A 7940IU, 0.8 g of lipid, 1.5 mg of niacin. Mugwort is characterized by a lot of minerals and vitamins. In particular, it has a lot of vitamin A. Vitamin A has an immune effect that brightens the eyes, strengthens the skin, and increases resistance to illness. Also, it contains a lot of vitamin C, which plays a role in the prevention and treatment of colds. have. In addition, the active ingredient of mugwort is known as cineol, choline, eucalyptol, adenine, monoginine, artemisine, etc., and it has strong blood circulation, detoxification, blood circulation, tonic, gangjeong, anti-inflammatory, analgesic, immunity, and diuresis. It has been found to be effective for hemostasis and appetite. In addition, mugwort has a unique fragrance, which is an essential oil component called chinol, and it is known that a unique odor component plays a beneficial role in the body and is strong in sterilization and insecticide. Garlic has anti-cancer effects and is effective in strengthening stamina, blood circulation, kidneys, bystanders, waste products, and paralysis of the lower body. Windproof is effective for human wind, pain, arthritis, quadriplegia, neuralgia. Tiredness is effective in strengthening bones, constipation, atherosclerosis, female physiology, and coldness.

Just as every power engine in the world needs fuel to move, every animal needs a fuel that can generate energy in order to work. The most important fuel is glucose. Humans also eat food to get this glucose, crush it, digest it, and then absorb the glucose in it into the blood, but one more step is needed for glucose to be used in our bodies. In other words, insulin, which is secreted from the pancreas (exactly beta cells of the Isle of Langelhans in the pancreas), must help glucose to be used in our bodies until our bodies use glucose as a fuel. It is a disease that occurs when glucose in the food enters the blood and causes abnormalities in the insulin secretory and cannot be used in our bodies. The glucose level in the blood increases and eventually goes out to the urine with water.

Diabetes is a chronic disease in which blood glucose (blood sugar) is higher than normal humans due to a lack of insulin, which causes glucose to be excreted in the urine.Insulin is released from B cells of the island of Langerhans in the pancreas, anterior pituitary gland and adrenal glands. (副 堅), thyroid gland, etc.

Endocrine gland hyperplasia, central nervous system, especially the hypothalamus lesions, etc. are caused by a combination of these factors, which is thought to be caused by heredity. Predisposition is important, and most of children and young patients are related to heredity, and diet is closely related to the onset. It is believed that this is related to total calories, high protein, and high fat diet, and moreover, the relationship with obesity is attracting attention because it is obesity in one third to half of patients.

It is true that many young people with diabetes are lean, and that the obesity of obese people after middle age is lightly healed only by controlling their weight. It is believed that the cause of the onset of pregnancy, the pregnancy is inferred to be a factor causing diabetes by some mechanism, the age of onset is mostly middle age, especially in the 40s to 60s. Incidence increases with age, incidence increases, more in men than women, and more in mental workers than manual workers.

Early stages of diabetes are polyuria, thirst, drowsiness, multi-food, weight loss, etc. Among these, thirst is the most common, followed by drowsiness, polyuria, and other factors such as genital ulcer, dysmenorrhea, Decreased libido, tooth decay (齒 檀 膿 漏) or tooth decay due to tooth decay. Complications include neuralgia, perceptual dysfunction, visual impairment and skin disorders (booth, lumps, boils, purulent purpura, eczema). Surgery, infection, fever if diabetes is left unattended for a long time or is not treated properly Diabetes may rapidly deteriorate due to the back and progress to diabetic acidosis. Diabetic asydos, also known as diabetic coma, is a disorder of consciousness caused by hyperglycemia of diabetes, which is commonly seen in young people with diabetes, and causes of inadequate treatment, especially with the discontinuation of insulin injections. Fever, infection, surgery

The symptoms of diabetes mellitus such as urination, thirst, and drowsiness, symptoms of nausea, nausea, and vomiting appear, dehydration is more pronounced, breathing is slow, frequency of breathing increases, and consciousness disorder is indifferent. From precision to coma

There are several stages.

Diabetes vascular disorders, neurological disorders, and infectious diseases are important factors for diabetic disease. Diabetic vascular disorders include arteriosclerosis of relatively thick blood vessels such as aorta, coronary arteries, and lower extremity, and small size of the retina and kidney (glomeruli). Atherosclerotic lesions in the blood vessels: coronary atherosclerosis, glomerulosclerosis in the kidneys, retinopathy in the eyes, hypertension, myocardial infarction, angina pectoris, proteinuria, renal failure, vision disorders, lower extremities, diabetic nerves Disorders include carbohydrate and lipid metabolism abnormalities such as peripheral neuropathy, decreased keyboard loss, loss, perception, and limb pain. In particular, the lower extremities may have symptoms such as night muscle pain, and may cause burning in the soles of feet, hyperalgesia, and tactile dullness, and are usually bilaterally symmetrical and rare on the playground. , Sweating, vulgaris, residual urination, delayed urination, urinary lungs, constipation, diarrhea can be seen.

Infections are often associated with diabetes mellitus, but the reasons for this are unclear, but include increased blood and tissue sugar content, decreased blood resistance to infections, and decreased nutritional status of cells. Human pyelonephritis and skin infections include pyoderma, swelling, boils, peritonitis, eczema and candidiasis of female genital organs. Diabetes can be controlled but not cured, and the goal of diabetes treatment is to stop the progression of diabetes and to prevent the occurrence and progression of complications that are common to diabetes. If it can't be controlled sufficiently, insulin therapy or oral medicine treatment is given. The living body can be said to be an aggregate of ultrafine particles of electricity depending on the viewpoint.

Each engine and each part function as a unique aggregate. Therefore, each part has a predetermined potential, and the distorted potential is a disease, and an electroencephalogram or an electrocardiogram is a device that detects a disorder by measuring a change in the potential. Looking at the potential of cancer cells is different from that of other normal cells.

We humans eat food in order to live, which is not excreted is excreted in feces, but what is absorbed in the digestive system is burned in the body by oxygen through various processes, and finally, it is excreted in the body as carbon dioxide and water. Gaseous carbon

Is combined with oxygen and comes out of the body by exhalation as another carbon dioxide. Another gas, hydrogen ions, is combined with oxygen and excreted in sweat or urine with water, but hydrogen is a cation, which is not useful at all in the body. Since the amount of oxygen required is also required, in this case, taking the Gundanhwan is combined with hydrogen instead of oxygen, so it is excreted without any waste of oxygen in the body. Will be done.

The present invention has completed the present invention by mixing the extract extracted from the bark of the oak bark with the concentrated solution of the concentrate of the various herbal medicines to produce a ring. An object of the present invention was to obtain a health functional food prepared in a pill by mixing the concentrated extract of various herbal medicines in the extract of the oak tree to obtain an excellent treatment and prevention effect on diabetes.

The present invention is 9% by weight of dried silkworm powder, 5% by weight of ripening scent, 5% by weight of cornus oil, 5% by weight of earthen cloth, 6% by weight of bokbunja, 5% by weight of saengsaeng, 5% by weight of Schisandra chinensis, 5% by weight of Schisandra chinensis, 8% by weight of mulberry leaves. Mix and knead the Chinese herbal medicine powder consisting of 5% by weight, 8% by weight of garlic, 8% by weight of kelp, 6% by weight of windproof, 5% by weight, 5% by weight of dandelion, 7% by weight of dandelion, and 8% by weight of chia seeds. It relates to a health functional food composition effective for blood circulation, joint protection, cerebrovascular disease, diabetes treatment and prevention, characterized in that it is produced in a pill.

The present invention is prepared by mixing the extract of the bark bark extract in the optimal conditions and concentrated concentrate of several herbal medicines to obtain a health functional food by taking the pill to obtain excellent treatment and prevention effect on diabetes and functional It is a very useful invention in the food industry.

The present invention is 9% by weight of dried silkworm powder, 5% by weight of ripening scent, 5% by weight of cornus oil, 5% by weight of earthen cloth, 6% by weight of bokbunja, 5% by weight of saengsaeng, 5% by weight of Schisandra chinensis, 5% by weight of Schisandra chinensis, 8% by weight of mulberry leaves. Mix and knead the Chinese herbal medicine powder consisting of 5% by weight, 8% by weight of garlic, 8% by weight of kelp, 6% by weight of windproof, 5% by weight, 5% by weight of dandelion, 7% by weight of dandelion, and 8% by weight of chia seeds. It relates to a health functional food composition effective for blood circulation, joint protection, cerebrovascular disease, diabetes treatment and prevention, characterized in that it is produced in a pill.

The present invention is 9% by weight of dried silkworm powder, 5% by weight of ripening scent, 5% by weight of cornus oil, 5% by weight of earthen cloth, 6% by weight of bokbunja, 5% by weight of saengsaeng, 5% by weight of Schisandra chinensis, 5% by weight of Schisandra chinensis, 8% by weight of mulberry leaves. , Herbal medicine 5% by weight, garlic 8% by weight, kelp 8% by weight, windproof 6% by weight, jichi 5% by weight, dandelion 7% by weight and 8% by weight of chia seeds Performing; Preparing the herbal medicine powder by drying and pulverizing the herbal medicine; Quantifying the pulverized medicinal herb powder and mixing in a blending ratio; Extracting the oak bark extract from a vacuum extruder by putting the oak bark in purified water; And mixing and kneading the mixed medicinal herb powder and the oak bark extract to prepare a circulating blood circulation, joint protection, cerebrovascular, diabetes treatment and prevention of a method for producing a health functional food composition effective for the prevention and treatment will be.

The present invention is to develop a geondanhwan using the extract of the moth extract 9% by weight silkworm, 5% by weight of sujijihyang, 5% by weight of cornus oil, 5% by weight of earthenware, 6% by weight of Bokbunja, 5% by weight of casualties, Fukryeong 5% by weight, 5% by weight of Schisandra chinensis, 8% by weight of mulberry leaves, 5% by weight, garlic 8% by weight, kelp 8% by weight, windproof 6% by weight, 5% by weight, dandelion 7% by weight, and 8% by weight of chia seeds It provides a dry polycyclic composition prepared by mixing the herbal medicine powder into a subsidiary material.

Extraction conditions of the bark bark used in the present invention using water as the extraction solvent and the extraction time is 6 ~ 7 hours 48 minutes, the temperature is 120 ℃. Storage stability experiment was conducted to establish concentration conditions in order to diversify and increase shelf life of extract of bark extract.

All. The extract was extracted under the conditions according to the above optimization, and the extract was concentrated under reduced pressure (70 ° C., 100 rpm) to fix ° Brix (single, 1, 2, 3, 4 ° Brix). 2, 3%) was added and refrigerated for storage for 4 weeks at 7 days intervals from the extraction date. At this time, the single (single) means the initial sugar state does not adjust the sugar. The pH of Brix at the initial stage of storage showed the highest pH of single extract, and the pH tended to decrease as Brix increased. As the storage period increased, the pH gradually increased, and during the last week of storage, the pH of the single extract increased significantly compared to other Brix extracts. This is believed to be due to the decay of this extract faster than other concentrates.

Example 1 Establishment of Optimal Extraction Conditions of Oak Trees

The domestic bark bark used in the present example was purchased in 2 years (9.00% moisture) and 3 years (10.82% moisture), which is currently cultivated in Gyeongju in 2009, and used after drying the bark. The experiment for setting the extraction conditions was fixed to a solvent ratio of 20 mL / g to the unpulverized sample was used a general reflux extraction device connected to a cooling tube.

Example 2 Conducting an Acute Toxicity Test

In order to prove the non-toxicity of the health functional food according to the present invention to the human body, an acute toxicity test was conducted in mice.

[Acute Toxicity Test]

(1) materials and methods

A) Experimental animal

1) Species: ICR mouse

2) Gender and age at acquisition: Male 4 weeks

3) Reason for selection: Since the ICR mice used in this experiment have been widely used in toxicology tests all over the world, it is rich in basic physiological, anatomical and toxicological data, so it is advantageous to compare the results. Selected for ease of use.

4) Source: Continental Test Animal

5) Quarantine and Purification Period: The laboratory was allowed to purify for about 1 week. During the period, general symptoms were observed and only healthy animals were used for the test.

6) Body weight range and age at intravenous injection: 20 ± 3g, 5 weeks

7) Number of animals: 100 (including preliminary test)

8) Group Separation and Animal Identification: The weight of healthy animals used in the test was divided into groups so that the average body weight of each group was almost identical.

B) animal room

1) Temperature and humidity range: temperature 22 ± 2 ℃, relative humidity 53 ± 2%

2) Contrast cycle: Fluorescent lighting (09:00 to 18:00 off)

3) Roughness: 150 ~ 300Lux

4) Types of breeding box: Polycarbonate cage for mouse during purifying, quarantine, administration and observation period (manufactured by Daejong Machinery)

5) Number of animals per breeding box: Purified, quarantine period-5, administration period-5

C) feed

1) Type: Solid feed for laboratory animals

2) Source: Samyang Oil Feed Co., Ltd.

D) negative

1) Type: filtered tap water

E) test substance

1) Sample: The composition prepared in Example 1 (1000-fold dilution)

Blank test amount (negative control)

F) Method of administration

1) Route of administration: Oral administration (Oral)

2) Number of administration and period of administration: 1 administration

3) Administration site and administration method: The mice were orally administered.

4) Administration time: 10: 00 ~ 12: 00

5) Dosage: 50ml / kg was administered immediately based on body weight.

(2) Test method

A) It was conducted in accordance with the National Institutes of Health toxicity test.

B) Clinical symptoms observation: All animals were conducted daily.

Six hours after the administration was observed every hour, and carefully observed the mobility, appearance and autonomic symptoms once daily for 5 days thereafter.

(3) Test result

As can be seen from the above results, two weeks after oral administration of the health functional food and the negative control group of the present invention, body weight and motility were observed to be normal.

Example 3: Hypoglycemic Effects of Dietary Supplements on Normal Rats

40 white rats weighing 20 ± 2 g are divided into four groups of 10 rats per group. For normal tanks without drug, an equivalent amount of physiological saline is administered to the abdominal cavity, and the drug tank is administered with glycenclamide (Glibenclamide) 5 mg / kg was administered, and 2 g / kg and 1 g / kg of the prepared health functional food were administered to the abdominal cavity for 15 days, respectively. Before administration and 15 days after administration, approximately 0.05 ml of blood was collected from the rat tail and the fasting blood glucose level was measured using a US JD2DGA7CC microglucometer. The health functional food of the present invention exhibits a hypoglycemic effect in normal pups, like glybenclamide, which has already been proven to be effective as an antidiabetic agent.

Example 4 Hypoglycemic Effects on the Functional Diabetic Rats Administered

White male and female males weighing 20 ± 2 g were tested together. Fasting for 12 hours before the experiment, and intraperitoneally injected 200mg / kg of a 2% solution prepared by mixing fresh in each tank except the normal tank. Fasting blood glucose in animals fasted 12 hours after 48 hours

40 rats with diabetes exceeding 16.67 mmol / L were divided into 4 groups of 10 animals per group. Ten normal birds were not administered. Normal and model tanks were given an equivalent amount of physiological saline to the abdominal cavity, and drug tanks were administered 5 mg / kg to the rat abdominal cavity, and the dietary functional food administration tank of the present invention 2g / kg and 1g / kg each was administered to the rat abdominal cavity for 15 days. Before administration and 15 days after administration, approximately 0.05 ml of blood was collected from the rat tail and the fasting blood glucose level was measured using a US JD2DGA7CC microglucometer. The health functional food of the present invention can be seen that significantly lower blood sugar in diabetic rats, like glybenclamide, which has already been proven effective as a therapeutic agent for diabetes.

Example 5 Hypoglycemic Effects on Adrenaline-treated Large Rats

50 Wister male rats weighing 180 ± 20 g were divided into 5 groups of 10 animals per group. Fast 24 hours before the experiment, inject 0.2 ml / kg of 0.1% adrenaline into the subcutaneous rats except normal rats, and inject the same amount of normal saline into the subcutaneous rats.

High doses of physiological saline were injected subcutaneously in each subcutaneous group and another drug was administered to the abdominal cavity immediately. After 90 minutes and 130 minutes, about 0.05ml of blood was collected from the tails of large rats, and blood glucose levels were measured using a US-based JD2DGA7CC microglucometer. It can be seen that the health functional food of the present invention reduces blood sugar of adrenaline diabetic large mice while hardly reducing blood sugar of normal mice.

Claims (2)

Silkworm dry powder 9%, ripening scent 5%, cornus oil 5%, earth and sand 5%, bokbunja 6%, casualty 5%, Bokryeong 5%, schizandra 5%, mulberry leaf 8%, powder 5 Prepared by mixing and kneading Chinese herbal medicine powder consisting of 8% by weight of garlic, 8% by weight of garlic, 8% by weight of kelp, 6% by weight of windproof, 5% by weight of dandelion, 8% by weight of dandelion and oak bark extract. Health functional food composition effective in blood circulation, joint protection, cerebrovascular, diabetes treatment and prevention, characterized in that one. Silkworm dry powder 9%, ripening scent 5%, cornus oil 5%, earth and sand 5%, bokbunja 6%, casualty 5%, Bokryeong 5%, schizandra 5%, mulberry leaf 8%, powder 5 Washing and precisely gendered herbal medicine consisting of 8% by weight, 8% by weight of garlic, 8% by weight of kelp, 6% by weight of windproof, 5% by weight, dandelion, 7% by weight of dandelion, and seed germination; Preparing the herbal medicine powder by drying and pulverizing the herbal medicine; Quantifying the pulverized medicinal herb powder and mixing in a blending ratio; Extracting the oak bark extract from a vacuum extruder by putting the oak bark in purified water; And mixing and kneading the mixed medicinal herb powder and the oak bark extract solution to prepare a circulating blood circulation, joint protection, cerebrovascular, diabetes treatment and prevention of the health functional food composition, characterized in that it comprises a step.