CN103027155A - Mulberry leaf lipid-reducing pressure-reducing health-care tea and preparation method thereof - Google Patents
Mulberry leaf lipid-reducing pressure-reducing health-care tea and preparation method thereof Download PDFInfo
- Publication number
- CN103027155A CN103027155A CN2013100084801A CN201310008480A CN103027155A CN 103027155 A CN103027155 A CN 103027155A CN 2013100084801 A CN2013100084801 A CN 2013100084801A CN 201310008480 A CN201310008480 A CN 201310008480A CN 103027155 A CN103027155 A CN 103027155A
- Authority
- CN
- China
- Prior art keywords
- parts
- mulberry leaf
- blood
- mulberry
- tea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses mulberry leaf lipid-reducing pressure-reducing health-care tea and a preparation method thereof. The mulberry leaf health-care tea comprises mulberry leaf main materials and traditional Chinese medicine auxiliary materials, wherein the traditional Chinese medicine auxiliary materials comprise eucommia ulmoides, angelica sinensis, poria cocos, viola philippica, codonopsis pilosula, polygala tenuifolia, gynostemma pentaphyllum, ligusticum wallichii, polygonatum odoratum, peach kernel, curcuma aromatic, raw rehmannia, radix angelicae dahuricae, earthworm, salviae miltiorrhizae, dandelion, glossy privet fruit, oldenlandia diffusa and white peony root. The invention overcomes the defects of the mulberry leaf tea is easy to yellow by heaping and fragile and the soup color is red. The advanced process of teat processing is integrated into manufacturing of the mulberry tea, the traditional tea-making deactivating technology is applied to development of the mulberry leaf, and the systematic research on the mulberry leaf tea preparation is performed by synthesizing various technological factors, so the developed mulberry leaf tea has good mouthfeel, high fragrance and no green smell and can be accepted by customers. The research proves that the mulberry leaf juice has anti-oxidant effect, no toxicity and no chemical pollution, and is expected to be an additive for food and health-care products. The traditional Chinese medicinal materials which can promote blood circulation, remove blood stasis, reduce blood sugar and reduce blood lipid are adopted and most of the traditional Chinese medicinal materials have light mouthfeel, so the taste of the mulberry leaf tea is not influenced, the mulberry leaf is easily accepted by people suffering from hypertension, hyperlipidemia and hyperglycemia, and the health-care effect can be achieved better.
Description
Technical field
The present invention relates to contain the hypoglycemic step-down blood fat reducing health products that derives from plant, animal component, particularly a kind of mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea and preparation method thereof.
Background technology
" three high diseases " refers to hypertension, hyperglycaemia (diabetes) and hyperlipemia.They are " rich man's diseases " that modern society is derived from, and possible individualism also may be interrelated.As: the diabetes patient is easy to suffer from simultaneously hypertension or hyperlipemia, and high fat of blood is the principal element of artery sclerosis formation and development, and the poor aggravation blood pressure of arteriosclerotic's blood vessel elasticity raises, so the later stage has all formed " three high diseases ".Be what has statistics about three height, in the Chinese ten large causes of death, the death rate relevant with metabolic disease is just up to 35.7%, and the death toll relevant with " three height " also accounts for 27% of total death toll.High fat of blood can cause blood vessel embolism; Hypertension can cause cerebral hemorrhage and rupture of blood vessel in brain; Hyperglycaemia can cause diabetes.The World Health Organization once clearly proposed, and prevented that the first line of defence of cardiovascular disease from reducing exactly " three height " and control " three height ".
A lot of diabetes patients are with hyperlipidemia, so people call sister's disease to diabetes and hyperlipidemia usually, and think that high fat of blood is the secondary disease of diabetes.About 40% diabetic has disorders of lipid metabolism according to statistics.Being characterized in that triglycerides increases with HDL reduces.Diabetes cause that the reason of Lipid increase is because during diabetes patient's insufficient insulin, body lactonase activity lowers, therefore easy Lipid increase.On the other hand diabetes simultaneously also companion's fat, protein and water, dielectric disorder except carbohydrate metabolism disturbance itself.Often there is free fatty from fat depot, to mobilize out, makes triglycerides and free fatty Enrichment in the blood.
The diabetes B people takes food too much on the one hand again, and motion is few, impels synthetic the increasing of the interior lipid of body, and this also is the reason that causes Lipid increase.And fat companion's high fat of blood person owing to the insulin receptor number reduces relatively, thereby produces insulin resistance, easily induced Diabetic.The Lipid increase person also easily causes the heart, cerebrovascular complication.Since ancient times, the traditional Chinese medical science just is applied to mulberry leaf clinical as the Chinese medicine for the treatment of diabetes (being the diabetes of modern medicine), and Japanese ancient book " eating tea health note " is also put down in writing the effect that mulberry leaf are improved drinking-water sick (being the diabetes of modern medicine).The studying data at home and abroad confirmation, alkaloid and polysaccharide are blood sugar reducing components main in the mulberry leaf.
1, hypoglycemic activity
The hypoglycemic activity of mulberry leaf is realized by two approach: the one, by alkaloid DNJ (1-DNJ) disaccharides catabolic enzyme activity is produced inhibitory action, thereby suppress small intestine to the absorption of disaccharide, reduce the peak value (Kimura, 1995) of the rear blood sugar of food; The 2nd, promoting by Folium Mori alkaloid fagomine and mulberry leaf polysaccharide that the β cell divides must insulin, and insulin can promote cell to the utilization of sugar, hepatic glycogen is synthetic and improve glycometabolism, finally reaches hypoglycemic effect (Chen Fujun etc., 1996).Isolated polyhydroxy norhyoscyamine has very strong glycosidase inhibiting function (Asano etc., 1994) from mulberry leaf; N-Me-DNJ, GAL-DNJ and fagomine can reduce blood sugar level significantly, wherein GAL-DNJ and fagomine hypoglycemic activity the strongest (Kimura etc., 1995).
2, hypotensive activity
Rutin sophorin in the mulberry leaf, Quercetin, quercitin can increase convergent force and the output quantity of stripped and the frog heart in place, and reduce heart rate.Rutin sophorin makes toad lower limb and rabbit ear vessel retraction, and the expansible coronary vasodilator of Quercetin improves the cardiac muscle circulation.GABA, rutin sophorin, quercitrin have hypotensive effect.GABA is the neural material of passing on, and can promote the metabolism of brain tissue and recover function of brain cell, simultaneously, can improve brain blood and flow, and strengthens the activity of Angiotensin-Converting I, impels blood pressure drops.
3, reducing blood lipid, norcholesterol, antithrombotic form and study of anti-atherogenic effect
Mulberry leaf have the formation that suppresses fatty liver, the effect that reduces serum fat and inhibition atherogenesis.Active component comprises DNJ, phytosterol, flavonoids etc.Contain the flavones ingredient of strengthening capillary, reducing blood viscosity in the mulberry leaf, Mulberry-leaf Tea contains the composition of LDL-lipoprotein oxidation in the antibody in addition, so mulberry leaf have again the effect of prevention myocardial infarction and cerebral hemorrhage when fat-reducing, improving hyperlipidemia.The good generation confirmation of Japan expert soil well, the hyperlipidemia serum lipids is raise mulberry-leaf extract and atherosclerotic has inhibitory action.Mulberry-leaf Tea can make hyperlipidemia rats serum high-density LP (HDL-C), HDL-CTC obviously raise (p＜0.05), T-CHOL (TC), LDL-C, triacylglycerol (TG) obviously reduce (p＜0.05), lipid peroxide (LPO) significantly reduces (p＜0.001), illustrate that Mulberry-leaf Tea can reduce blood fat, softening blood vessel, removing body endoperoxide, thereby the rising of hyperlipidemia serum lipids and atherosclerotic there is inhibitory action (Huang Daiqing etc., 1995).
4, blood coagulation resisting function
Mulberry-leaf extract can obviously prolong activating part APTT (APTI) time, factor (PT) time and fibrin ferment (TT) time of the interior WBCT of Mice Body and significant prolongation plasma in rabbit.Divide exogenous and two links of endogenous because coagulation process starts link, the activity of APTI reflection intrinsic coagulation approach, the activity of PT reflection exogenous cruor pathway, and the TT reflection is that both common pathways are thrombin activity.Illustrating that mulberry leaf are to fibrin ferment--the fibrinogen reaction has direct repression.
5, antibacterial, antiinflammatory action
White mulberry vein-juice has good inhibition growth (Fan Lisheng, 2001) to most of gram-positive bacterias and Gram-negative bacteria and part saccharomycete.And required Mlc is low, pH value scope is that wide (4-9), heat endurance are strong.Rutin sophorin in the mulberry can significantly suppress the Rat Models of Traumatic edema, and can stop the development of conjunctivitis, auricle inflammation, pulmonary edema.Mulberry leaf have stronger antiinflammatory action, with dispel the wind, heat-clearing effect conform to (Chen Fujun etc., 1995)
6, antiviral, antitumor action
Mulberry leaf can prevent cancer cell to generate, and improve body immunity, and the major function composition is DNJ, flavonoids, Sang Su, GABA and vitamin, can suppress chromosome mutation and gene mutation.DNJ has significant anti-reverse transcription enzymophathy cytotoxic activity (Tierney, 1995).Its IG30 is 1.2-2.5 μ gmL, and with the increase of DNJ dosage, restraint strengthens (Ou Yangzhen, 2003).DNJ is 80.5% to the inhibiting rate of metastases, and it suppresses mechanism may be that DNI produces immature carbohydrate chain by the activity that suppresses glycosidase at tumor cell surface, has weakened the transfer ability of tumour.Two kinds of flavonoids Quercetins of separation and purification-3-β-D glucopyranoside and Quercetin-3-7-dioxy-β-D-glucopyranoside reveal significant depression effect to the growth table of human promyelocytic leukemia cell (HL-60) in Korea scholar Kim (2000) the discovery mulberry leaf.Sang Su in the mulberry leaf has active anticancer, and the vitamin in the mulberry leaf has the mutagen of inhibition effect.
7, anti-ageing, antifatigue effect
Clinical pharmacology research institute of Zhejiang University passes through the experiment (Zhao Lijun etc., 2004) in 4 years, confirms that mulberry leaf have help and the anti-aging effects that is similar to ginseng.Ginseng belongs to be vulcanized, and mulberry leaf belong to clearly benefit, the Wuji limit, and no matter old children all can use, and suitable for four seasons.In addition, the compositions such as contained Quercetin, phenolic compound, vitamin C can be by suppressing or remove free radical to prevent oxidative damage in the mulberry leaf.Mulberry leaf have help and the effect anti-ageing, that stablize nervous function of similar ginseng, can alleviate excited that physiological change causes, improve the activity of superoxide dismutase in the body, stop the generation of harmful substance in the body, reduce or eliminate the lipofuscin (Huang Dong etc., 2000) in body of producing and stagnate.Mulberry leaf can improve mouse to the tolerance of high temperature stimulation and prevent because the adrenal cortex distributed function that stress stimulation causes is low, and when adrenal function was low, it is normal that mulberry leaf can make it to recover.Mulberry leaf can prolong mouse swimming and transfer rod time, have the body of enhancing Endurence, can prolong the life-span of fruit bat.Can effectively remove the superoxide anion that biological oxidation produces, have the effect (Tang Fadi etc., 2000) that delays senility.
Although the mulberry leaf magical effect is a lot, can develop quite difficult.Aspect product development. Japanese Feng Yu healthy food company has produced the products such as Mulberry-leaf Tea with Mulberry Leaf, drinking method is identical with green tea, is dissolved in the boiling water or is stirred in the food all can.At first be exactly that mouthfeel is not good, but because the impact of composition in the mulberry leaf, the Mulberry-leaf Tea of processing through general manufacture craft still has a kind of unpleasant green odour and bitter taste.Be difficult to allow the people accept, the processing technology of product is never effectively improved.How to accomplish dark brown breen, the soup look greenish-yellow, and sweet tasty and refreshing, sweet-smelling is permanent, improves the health-care effect of mulberry leaf, allows increasing people accept this healthy drink, is only present mulberry leaf and extracts the huge challenge that manufacture craft faces.
Summary of the invention
Technical problem to be solved by this invention is, not good for the Mulberry-leaf Tea mouthfeel that prior art exists mulberry leaf to make, the soup color contamination is ignorant, and fragrance mainly comes Titian by auxiliary material, does not reach the requirement that conventional tea looks good, smell good and taste good; And health care reducing blood sugar and blood fat effect is fully performance, and function is undesirable, and is not have well provided a kind of Mulberry-leaf Tea of blood fat-reducing blood pressure-decreasing by the shortcoming of three high personages' acceptance.The present invention considers the advanced technologies of Tea Processing is integrated in the making of Mulberry-leaf Tea, and traditional tea making technology of completing is applied to the development of Mulberry-leaf Tea, comprehensive every technique factor has been carried out than systematic research mulberry leaf tea making, and the Mulberry-leaf Tea mouthfeel of development is good, fragrance is high, without blue or green stink, can accept to confirm that after deliberation white mulberry vein-juice has antioxidation for consumption, nontoxic, without chemical contamination, be expected to become food and products and health products additive agent.Add that some are promoting blood circulation and removing blood stasis, hypoglycemic, the Chinese medicine of reducing blood lipid, the most mouthfeel of these medicinal materials is light, does not affect the Mulberry-leaf Tea taste, makes the people be easy to accept, and more can reach preferably the effect of health care.
For solving the problems of the technologies described above, the invention provides a kind of mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea, comprise mulberry leaf major ingredient and Chinese medicine auxiliary material; Wherein, the parts by weight of various bulk drugs are in the described Chinese medicine auxiliary material: 10～20 parts of the barks of eucommia, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts in Poria cocos, 10～20 parts of Chinese violets, 10～20 parts of Radix Codonopsis, 10～20 parts of polygala roots, 10～20 parts of gynostemma pentaphylla, 10～20 parts of Ligusticum wallichiis, 10～20 parts of radix polygonati officinalis, 10～20 parts in peach kernel, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts in the dried rhizome of rehmannia, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of earthworms, 10～20 parts of the reds sage root, 10～20 parts of dandelions, 10～20 parts of the fruit of glossy privets, 10～20 parts of oldenlandia diffusas, 10～20 parts of the root of herbaceous peonys.
The parts by weight of various bulk drugs also can be 10～15 parts of the barks of eucommia in the described Chinese medicine auxiliary material, 10～15 parts of Radix Angelicae Sinensis, 10～15 parts in Poria cocos, 10～15 parts of Chinese violets, 10～15 parts of Radix Codonopsis, 10～15 parts of polygala roots, 10～15 parts of gynostemma pentaphylla, 10～15 parts of Ligusticum wallichiis, 10～15 parts of radix polygonati officinalis, 10～20 parts in peach kernel, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts in the dried rhizome of rehmannia, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of earthworms, 10～20 parts of the reds sage root, 10～20 parts of dandelions, 10～20 parts of the fruit of glossy privets, 10～20 parts of oldenlandia diffusas, 10～20 parts of the root of herbaceous peonys.
The parts by weight of various bulk drugs can also be 10～20 parts of the barks of eucommia in the described Chinese medicine auxiliary material, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts in Poria cocos, 10～20 parts of Chinese violets, 10～20 parts of Radix Codonopsis, 10～20 parts of polygala roots, 10～20 parts of gynostemma pentaphylla, 10～20 parts of Ligusticum wallichiis, 10～20 parts of radix polygonati officinalis, 10～15 parts in peach kernel, 10～15 parts of root tubers of aromatic turmeric, 10～15 parts in the dried rhizome of rehmannia, 10～15 parts of the roots of Dahurain angelica, 10～15 parts of earthworms, 10～15 parts of the reds sage root, 10～15 parts of dandelions, 10～15 parts of the fruit of glossy privets, 10～15 parts of oldenlandia diffusas, 10～15 parts of the root of herbaceous peonys.
The parts by weight of various bulk drugs can be 15～20 parts of the barks of eucommia again in the described Chinese medicine auxiliary material, 15～20 parts of Radix Angelicae Sinensis, 15～20 parts in Poria cocos, 10～15 parts of Chinese violets, 10～20 parts of Radix Codonopsis, 10～20 parts of polygala roots, 10～20 parts of gynostemma pentaphylla, 15～20 parts of Ligusticum wallichiis, 10～20 parts of radix polygonati officinalis, 10～15 parts in peach kernel, 10～15 parts of root tubers of aromatic turmeric, 10～15 parts in the dried rhizome of rehmannia, 10～15 parts of the roots of Dahurain angelica, 10～15 parts of earthworms, 10～15 parts of the reds sage root, 10～15 parts of dandelions, 10～15 parts of the fruit of glossy privets, 10～15 parts of oldenlandia diffusas, 10～15 parts of the root of herbaceous peonys.
For solving the problems of the technologies described above, a kind ofly it is characterized in that such as the preparation method of mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea as described in each in the claim 1～3, may further comprise the steps:
A. select mulberry leaf;
B. chopped leaves of mulberry leaf;
C. complete;
D. knead; Bake and bank up with earth, make the mulberry leaf major ingredient;
E. with Chinese medicine auxiliary material granulation;
F. with Chinese medicine granules of accessories obtained above agent and the mulberry leaf major ingredient of making by 8～15: pack after 1 part by weight mixes.
Among the described step a, can gather first on the mulberry tree without the 2-3 position mulberry leaf of disease and pest, elutriation is dried, and puts in order overlapping.
Among the described step b, can cut petiole, mulberry leaf are cut into filament, 2-4 centimetre wide.
Among the described step c, can put into frying pan to the mulberry leaf filament, heating completes, first slow fire heating, and the temperature that slowly raises cools when the leaf look becomes strong green.
In the described steps d, the mulberry leaf spire after completing can kneaded in large iron pan, backward downwards first on, firmly evenly, when filament leaf bar rope is tighter, becomes and then cure when dark brown; Put into 80-100 ℃ baking machine turning in and fry moulding in 30-45 minute, make the mulberry leaf major ingredient.
Among the described step e, described all the other bulk drugs can be dropped in the multi-function extractor, add weight portion 5-10 times of water gaging for the first time and decocted 1-2 hour, add weight portion 4-8 times of water gaging for the second time and decocted 1-2 hour, merge decocting liquid twice, filter to get filtrate; Leave standstill, remove supernatant, heating is concentrated into pasty state, adds starch, then puts into granulator and makes 1-2 centimetre of particle.
Among the described step f, the mulberry leaf major ingredient that the Chinese medicine granules of accessories that makes and above-mentioned steps can be made is by 1: 8～15 weight proportion, the moulding of pack packing.
In the described Mulberry-leaf Tea, the weight proportion of mulberry leaf major ingredient and Chinese medicine auxiliary material also can for, 6: 1,7: 1,9: 1,12: 1,14: 1,18: 1 or 20: 1.
Directly increasing mixing in water for oral taking when Mulberry-leaf Tea of the present invention is used gets final product.
The invention solves the Mulberry-leaf Tea mouthfeel not good, frangible, the shortcoming that the soup look rubescent, the present invention makes the polyphenol substance in the mulberry leaf convert as far as possible amino acid to, is conducive to remove bitter taste in the tea, makes it more delicious; And the nutriment that has kept greatly mulberry leaf makes it not have work in-process to run off, and has on the make avoided secondary pollution, is the blood fat-reducing blood pressure-decreasing health protection tea of green health environmental protection fully.Be conducive to blue or green flavor behind the green removing in high temperature, improved fragrance, improve mouthfeel; The present invention considers the advanced technologies of Tea Processing is integrated in the making of Mulberry-leaf Tea, in conjunction with tea aroma raising technique, and comprehensive every technique factor, mulberry leaf tea making has been carried out than systematic research, and the Mulberry-leaf Tea mouthfeel of development is good, and fragrance is high, without blue or green stink, can accept for three high crowds.
The specific embodiment
The research report, the studying data at home and abroad confirmation, alkaloid and polysaccharide are blood sugar reducing components main in the mulberry leaf.
1, hypoglycemic activity
The hypoglycemic activity of mulberry leaf is realized by two approach: the one, by alkaloid DNJ (1-DNJ) disaccharides catabolic enzyme activity is produced inhibitory action, thereby suppress small intestine to the absorption of disaccharide, reduce the peak value (Kimura, 1995) of the rear blood sugar of food; The 2nd, promoting by Folium Mori alkaloid fagomine and mulberry leaf polysaccharide that the β cell divides must insulin, and insulin can promote cell to the utilization of sugar, hepatic glycogen is synthetic and improve glycometabolism, finally reaches hypoglycemic effect (Chen Fujun etc., 1996).Isolated polyhydroxy norhyoscyamine has very strong glycosidase inhibiting function (Asano etc., 1994) from mulberry leaf; N-Me-DNJ, GAL-DNJ and fagomine can reduce blood sugar level significantly, wherein GAL-DNJ and fagomine hypoglycemic activity the strongest (Kimura etc., 1995).
2, hypotensive activity
Rutin sophorin in the mulberry leaf, Quercetin, quercitin can increase convergent force and the output quantity of stripped and the frog heart in place, and reduce heart rate.Rutin sophorin makes toad lower limb and rabbit ear vessel retraction, and the expansible coronary vasodilator of Quercetin improves the cardiac muscle circulation.GABA, rutin sophorin, quercitrin have hypotensive effect.GABA is the neural material of passing on, and can promote the metabolism of brain tissue and recover function of brain cell, simultaneously, can improve brain blood and flow, and strengthens the activity of Angiotensin-Converting I, impels blood pressure drops.
3, reducing blood lipid, norcholesterol, antithrombotic form and study of anti-atherogenic effect
Mulberry leaf have the formation that suppresses fatty liver, the effect that reduces serum fat and inhibition atherogenesis.Active component comprises DNJ, phytosterol, flavonoids etc.Contain the flavones ingredient of strengthening capillary, reducing blood viscosity in the mulberry leaf, Mulberry-leaf Tea contains the composition of LDL-lipoprotein oxidation in the antibody in addition, so mulberry leaf have again the effect of prevention myocardial infarction and cerebral hemorrhage when fat-reducing, improving hyperlipidemia.The good generation confirmation of Japan expert soil well, the hyperlipidemia serum lipids is raise mulberry-leaf extract and atherosclerotic has inhibitory action.Mulberry-leaf Tea can make hyperlipidemia rats serum high-density LP (HDL-C), HDL-CTC obviously raise (p＜0.05), T-CHOL (TC), LDL-C, triacylglycerol (TG) obviously reduce (p＜0.05), lipid peroxide (LPO) significantly reduces (p＜0.001), illustrate that Mulberry-leaf Tea can reduce blood fat, softening blood vessel, removing body endoperoxide, thereby the rising of hyperlipidemia serum lipids and atherosclerotic there is inhibitory action (Huang Daiqing etc., 1995).
Key is to contain in the mulberry leaf phytosterol, flavones and isoflavones.Have research report DIESF phytosterol and flavones can suppress the absorption of enteron aisle inner cholesterol, flavones can also reduce blood viscosity, strengthens capillary, improves heart and liver function.The Li Shui effect of mulberry leaf both can be urinated, and can drain moisture unnecessary in the cell again, simultaneously neutral fat and cholesterol superfluous in the blood was cleared, and when the blood neutral fat reduced, the fat of storage just discharged.Contain more crude fibre, essential amino acid, vitamin and mineral matter in the mulberry leaf.Therefore, mulberry leaf can prevent myocardial infarction and cerebral hemorrhage again when improving hyperlipidemia.
The mulberry leaf flavor is sweet, bitter, cold in nature, nontoxic, enters liver, lung channel.Mulberry leaf are cured the disease to be used as medicine and are started from the Eastern Han Dynasty, classify " middle product " in the Shennong's Herbal as, and its meaning is to nourish one's nature.Modern Chinese medicine custom is listed it in the relieving the exterior syndrome with drugs pungent in flavor and cool in property class medicine in, is used as wind and heat dispersing, cooling blood and hemostasis, clears liver and improve vision, and mulberry leaf also have the effect that ends night sweat in fact." Bencao Jingshu ": " herbal classic " odorlessness.It cures mainly in detail, should be that the sweet gas of flavor is cold nontoxic.So sweet beneficial blood, so cold cool blood, therefore sweet cold being harmonious is lower gas and benefit is cloudy.Be with the main deficiency of Yin fever and chills of energy, and Yin Neire perspire.Its property is held concurrently dry, therefore can remove beriberi oedema, sharp intestine and small intestine again.The golden gas of former official report is therefore can remove wind again.Through frost the respectful clearly of the world that then get both, quench the thirst therefore can make eye bright again.Send out the person, after the blood, therefore beneficial blood again can long hair, therefore cool blood antiemetic blood again.Close the carbuncle mouth, net for catching birds or fish is worn the palm, treats the soup fire, and all refrigerant merit of enriching blood also.Compendium of Material Medica: mulberry leaf are hand, the bright medicine of foot sun, control the labor heat cough, and the long hair that makes eye bright is only quenched one's thirst." book on Chinese herbal medicine newly organized ": the merit of mulberry leaf, better for the mulberry skin, the marrow in the kind benefit bone, add the essence in the kidney, end the sweat in the body, fill out brain and make eye bright, invigorate blood circulation and promote the production of body fluid, seed is antiabortive, the mediation blood vessels, easing joint movement, end cholera and vomit and diarrhoea, except rheumatism and arthritis, the consumer edema pin is floating, and Laonan people can hold up and decline oldly, and the old woman can also give birth to youngster less.Mulberry leaf picking leaves such as tea are planted large person the first, and large person takes second place again, and less person takes second place again.Little with it, rather greatly also.Excessive, then only can fry in shallow oil soup to be used as medicine, having may be loose for ball.Wash order, should get old mulberry leaf, the person that certainly do not fall is useless.Modern medicine and pharmacology research finds that flavone compound accounts for 1%～3% of mulberry leaf dry weight in the mulberry leaf, is the higher class plant of cauline leaf content in the plant kingdom.Korea S and Japanese scholars are isolated 9 kinds of flavonoids from mulberry leaf, mainly be the compounds such as rutin sophorin (rutin), Quercetin, isoquercitrin, Quercetin-3-three glucosides.Alkaloid is the main active of mulberry leaf, (1994) such as Japanese scholars Asano isolate multiple polyhydroxylated alkaloid from mulberry leaf, comprise DNJ (1-DNJ), N-methyl isophthalic acid-DNJ (N-Me-DNJ), 2-oxygen-α-D synthesis-1-DNJ, fagomine, 1,4-dideoxy-1,4-imido grpup-D-R alcohol, 1,4-dideoxy-1,4-imido grpup-pure and mild 1 α of (2-oxygen-β-D-glucopyranoside)-D-R, 2 β, 3 α, 4 β-tetrahydroxy-go, 7 kinds of alkaloids such as first gelsemium henbane alkane (removing the first Daturine).Wherein DNJ (1-DNJ) is in plant kingdom, and only mulberry leaf are exclusive.
Radix Codonopsis is China's traditional tonic commonly used, and the Radix Codonopsis that produce take area, Shangdang, Shanxi ancient times has tonifying middle-Jiao and Qi as top grade, the effect of invigorating the spleen benefit lung.Modern study, Radix Codonopsis contain various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, saponin and Alkaloid, have to strengthen immunity, hemangiectasis, step-down, improve microcirculation, strengthen the effect such as hematopoiesis function.The leucocyte that in addition chemotherapy radiotherapy is caused descends castering action is arranged.Radix Codonopsis has tonifying middle-Jiao and Qi, the effect of invigorating the spleen benefit lung.Be used for a little less than the spleen deficiency syndrome of the lung, the palpitaition of breathing hard, anorexia and loose stool, void is breathed with cough and is coughed, and interior heat is quenched one's thirst etc." new compilation of materia medica " record: " tonifying middle-Jiao and Qi and taste, relieving thirst and restlessness.Middle gas is faint, mends in order to transfer, and is very smooth and proper.”
Gynostemma pentaphylla is found through modern medicine study, the main active ingredient of gynostemma pentaphylla is polysaccharide, flavonoids, saponins and microelement kind, its effect mainly is to promote body fat class metabolism, nutrition human body cell, have simultaneously good detoxicating, relieving inflammation effect, be widely used in treatment and the health care of high fat of blood, fatty liver, obesity, constipation, insomnia, hepatitis B, chronic respiratory inflammation (sphagitis, enterogastritis etc.).
Poria cocos flavor is sweet, light, property flat, be used as medicine have clearing damp and promoting diuresis, the function of beneficial spleen and stomach, antitoxic heart-soothing and sedative.Modern medicine study: Poria cocos can enhanced machine body immunity function, pachymaran has significantly antitumor and protect the liver dirty effect.The Poria cocos slightly sweet flavor is flat, enters the heart, lung, the spleen channel.Has eliminating dampness and diuresis, strengthening the spleen and stomach, the effect of antitoxic heart-soothing and sedative.Can control difficult urination, the oedema turgor, phlegm and retained fluid is coughed contrary, vomits contrary, and vomiting during early pregnancy is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful disease such as grade.The Li Shui of Poria cocos reaches by strong fortune spleen PFT, and is different from the Chinese medicine of other direct Li Shui.Be used for splenasthenic diarrhea, the lower Poria cocos of band can invigorating the spleen, again can excreting dampness, and due to insufficiency of the spleen dysfunction of the spleen in transportation and transformation, have loose bowels, be with down, use the effect that Poria cocos has giving consideration to both the incidental and fundamental, often and the compatibilities such as Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam.Can be used as the tonifying lung spleen, control the adjuvant of the deficiency of vital energy.
Ligusticum wallichii is hot, temperature.Return liver, courage, pericardium channel.The function blood-activating and qi-promoting, wind-expelling pain-stopping.Be used for irregular menstruation, through closing dysmenorrhoea, abdominal mass stomachache, the shouting pain of the chest side of body, tumbling and swelling, headache, arthralgia due to wind-dampness.Rhizome of chuanxiong is warm in nature, is gynaecology's common drug, and the effect of activating blood cirulation to regulate QI flow is arranged, but can not be multiplex, and especially health has the people of bleeding to be not suitable for taking, such as female menstrual period.Simultaneously, rhizome of chuanxiong is again one of medicinal material commonly used in the herbal cuisine, with black-bone chicken with food, can nourishing yin and activating blood, be women's excellent tonic product.
The red sage root is bitter, is slightly cold.The thoughts of returning home, Liver Channel.Stasis-dispelling and pain-killing, activating blood to promote menstruation, relieving restlessness clears away heart-fire.Be used for irregular menstruation, through closing dysmenorrhoea, a lump in the abdomen causing distension and pain, chest ventral spine pain, and hot numbness pain, sore swells and ache, dysphoria and insomnia.Be used for the sternal rib hypochondriac pain, arthralgia due to wind-dampness, the abdominal mass caking, sore swells and ache, fall fall forward grieved, irregular menstruation, through closing dysmenorrhoea, postpartum stasis of blood pain etc.Treatment sternal rib pain, abdominal mass caking, and irregular menstruation, bitterly have good effect through amenorrhoea.. " detailed outline " carries: the red sage root, by " the sensible opinion of married woman " cloud, Siwu Tang is controlled the gynecopathy, pays no attention to antenatal postpartum, through water what, all can be general, the only flavor red sage root is loose, cures mainly identical with it.The lid red sage root can break place blood, mends new blood, peaceful tire, and the stillborn foetus that falls, under only metrorrhagia stagnates, the menstruation regulating arteries and veins.The Main Compositions of Radix Salviae Miltiorrhizae tanshinone has hemangiectasis, improves effects such as circulating, remove intravascular coagulation, has the effect of invigorating blood circulation trace, and can promote the liver blood circulation to be beneficial to liver cell regeneration.
The radix polygonati officinalis flavor is sweet, and property is flat.Return lung; The stomach warp.Nourishing Yin and moistening lung; Nourishing the stomach to improve the production of body fluid.Cough caused by dryness; Labor is coughed; The dry throat and mouth of the cloudy liquid consumption of pyreticosis wound; Interior heat is quenched one's thirst; Deficiency of Yin diseases caused by external factors; Dizzy dizzy; Muscle arteries and veins contraction pain.The radix polygonati officinalis sweet greasiness of distinguishing the flavor of, matter is gentle and moisten, and is the good medicine of nourishing Yin and promoting production of body fluid simply.Contained vitamin A in the radix polygonati officinalis improves dry and cracked, rough skin situation, makes it soft lubricated.Play the effect of beauty and skin care." detailed outline ": " main air temperature spontaneous perspiration is scorching hot, and the malaria with general debility fever and chills, and taste void is weary, and man's frequent urination is lost essence, and all are deficient.”
Radix Angelicae Sinensis: its flavor is sweet and weigh, therefore specially can enrich blood, its gas is light and hot, thus again can promoting circulation of blood, and bowl spares has, in the row benefit is arranged, the gas medicine in the sincere blood, the also panacea in the blood.About mending to mend then of assistant, thus can support nutrition blood, the tonifying Qi production of sperm, five viscera settling, body by force, beneficial mind, all tangible deficient diseases, nothing is unsuitable.Assistant logical to attack then, therefore the pain defaecation of dispelling, relieving rigidity of muscles and joints is controlled contraction, paralysis, the card such as dry, puckery.Seek void and the exterior syndrome being not relieved person, help with agent such as bavin, Pueraria lobota, fiber crops, osmanthus, the Biao Weire that can fall apart greatly, and table is not held back the person, and assistant can be shown again admittedly with rheum officinale and so on.Precisely because gas Xin Erdong, therefore want its quiet person when keeping away it, the sliding benefaction of property is defecated and is not consolidated the person when keeping away it.All cloudy moderate heat Sheng persons, the active blood of Radix Angelicae Sinensis, also non-institute is suitable, cloudy deficiency of YANG of middle-JIAO person, Radix Angelicae Sinensis can nourish blood, and is indispensable.
Peach kernel is bitter, and is sweet, puts down the special medicine that closes for blood stasis blood.Bitter to let out stagnant blood, the new blood of Gan Yisheng." medicineization justice ": peach kernel, bitter can rush down blood-head, and it is dry that the body profit can be grown intestines.If it is multiplex that gross weight grinds, walk Liver Channel, the main broken blood that holds, month by month water, and pain all over, four limbs wood numbness, left hemiplegia, left sufficient patient is relaxed through the promoting circulation of blood of invigorating blood circulation with it, the merit that eliminate blood stasis and promote tissue regeneration is arranged if few usefulness is mashed in peeling, enters large intestine, controlling blood depletion just closes, blood is dry just difficult, with its make moist cool blood and blood, the logical power that stagnates of knot is arranged out.
The fruit of glossy privet is used for the order of the deficiency of liver-yin and kidney-yin and secretly fails to understand hypopsia, poliosis, soreness of waist tinnitus and fever due to yin deficiency etc.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, must slowly get effect.Control order secretly not clear, often join cultivated land, matrimony vine is equal to usefulness, controls poliosis, often joins the same usefulness of mulberries, and the root bark of Chinese wolf-berry is often joined in fever due to yin deficiency.The deficiency of liver-yin and kidney-yin, Light-headedness, seminal emission tinnitus, soreness and weakness of waist and knees, poliosis, coronary heart disease, hyperlipidemia, hypertension, chronic hepatitis.Protective effect research to liver is thought, the fruit of glossy privet contains oleanolic acid, give rat skin lower injection, can reduce serum glutamic pyruvic transminase, hepatic injury to Carbon Tetrachloride Induced has obvious protective effect, and can promote liver cell regeneration. and oleanolic acid also can make in the liver triglycerides accumulate that minimizings, degeneration of liver cells necrosis obviously alleviate, glycogen is accumulated increase, the decline of serum Y globulin; Mitochondrial swelling and the sex change of endoplasmic reticulum vesica alleviates, the matter inflammatory reaction weakens between hepatic tissue in the visible liver cell of ultra microstructure.
Root tuber of aromatic turmeric is hot, bitter, and is cold.Return liver, the heart, lung channel.Function cures mainly regulating qi to disperse stagnation, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice.Be used for through closing dysmenorrhoea, chest and abdomen swelling and pain, shouting pain, the pyreticosis coma, epilepsy is gone mad, and jaundice urine is red.Promoting qi circulation and removing obstruction in the collateral, cool blood breaks the stasis of blood.Control all pains of chest abdomen side of body rib, lose the heart demented, the pyreticosis coma is spitted blood, bleeding from five sense organs or subcutaneous tissue, and hematuria, blood drenches, women's vicarious menstruation, jaundice." property of medicine opinion " carries it: control woman place vim and vigour pained, the cold air knot is poly-, and warm vinegar rubs and takes it.Tang Materia Medica carries it: main blood is long-pending, lower gas, and myogenic, hemostasis, broken extravesated blood, blood drenches, hematuria, metal-inflicted wound.
Root of Dahurain angelica meridian distribution of property and flavor: suffering, temperature.Attach to the lung and stomach meridians.Expelling wind and clearing away cold, understand things pain-stopping, detumescence and apocenosis, eliminating dampness is ended band." Japan hanako materia medica ": control the hot eyes triangular mass of mucous membrane growing from the inner corner of the eye, and tire patching leakage landing, broken place blood is mended new blood, acute mastitis, carbuncle on the back, scrofula, intestines wind, hemorrhoid complicated by anal fistula, and apocenosis, desolation, mange, the pain relieving myogenic is gone face Shao-defect scar.
The root of herbaceous peony enters liver, the spleen channel, nourishing blood and liver, and slow middle pain relieving, astringe yin is received sweat.Control chest abdomen pain over the hypochondriac region, rush down dysentery stomachache, spontaneous sweating, fever due to yin deficiency, irregular menstruation, uterine bleeding, band is lower, and it is obstructed that married woman's blood closes, and the hemostasis that disappears can lose purulence, beneficial woman's blood." Japan hanako materia medica ": control wind, mend labor, all diseases of main woman, and antenatal rear all diseases, Tong Yueshui brings down a fever, relieving restlessness, beneficial gas, day hot disease of row, the pest miasma, frightened mad, married woman's blood fortune, and intestines wind are rushed down blood, hemorrhoid complicated by anal fistula.Carbuncle on the back, the sore scabies, headache makes eye bright, and hot eyes is exerted meat.The many tonifying Qi of redness of the skin or complexion person, white person controls blood.
The bark of eucommia in recent years, both at home and abroad the expert has carried out repeatedly careful research to bark of eucommia composition, bark of eucommia free amino acid is few, a small amount of protein that contains, be with most foodstuffs like adequate proteins, namely can be hydrolyzed 8 seed amino acids that detect needed by human.Measure 15 kinds of contained mineral elements of the bark of eucommia, the trace elements such as zinc, copper, iron have wherein been arranged, reached the macroelements such as calcium, phosphorus, potassium, magnesium.The bark of eucommia has filling liver kidney, and rubbish in the body is removed in strengthening the bones and muscles, strengthen the human body cell metabolism, prevent that muscle skeleton is aging, the balance human blood-pressure, the decomposer inner cholesterol, reduce body fat, recover blood vessel elasticity, the diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system improves white blood cell count, strengthens the remarkable efficacy such as body immunity.
Radix rehmanniae recen has the effect of clearing heat and cooling blood, beneficial Yin and promoting production of body liquid.Li Shizhen (1518-1593 A.D.) to the evaluation of radix rehmanniae recen is: " one hundred days of clothes are rosy cheeks, make light of one's life by commiting suicide not old in 3 years." heat-clearing, promote the production of body fluid, cool blood; Radix rehmanniae recen: heat-clearing, promote the production of body fluid, moisturize, laxation, the broken stasis of blood, give birth to new, pain relieving, menstruation regulating, the metal-inflicted wound stasis of blood, cool blood, hemostasis.Shennong's Herbal: distinguish the flavor of sweet, cold.Cure mainly folding and fall, muscle in the wound, by blood-arthralgia, is filled out marrow, longue meat absolutely.Make soup and gather except fever and chills, except numbness.The survivor is especially good.
Polygala root is bitter, hot, tepor.The thoughts of returning home, kidney, lung channel.Function cures mainly the intelligence development of calming the nerves, and eliminates the phlegm detumescence.Be used for the insomnia and dreamful sleep that breakdown of the normal physiological coordination between the heart and the kidney causes, forgetful palpitation with fear, wandering, expectoration is not well, sore swollen toxin, mastosis.Be applied to insomnia and dreamful sleep, palpitation and severe palpitation, forgetful.This product toil is warm in nature, property is kind lead off sensible, happily gas and antitoxic heart-soothing and sedative, can lead to kidney qi and strong will is not forgotten, be the by force good merchantable brand of knowledge of restoring normal coordination between heart and kidney, stable mind, intelligence development.Cure mainly the diseases such as the having no peace of mind of breakdown of the normal physiological coordination between the heart and the kidney, insomnia, palpitation with fear, normal and the same usefulness of medicinal for tranquilizing mind such as fushen, dens draconis, cinnabar are such as polygala root ball (" the Zhang Shi doctor is led to "); Control forgetful card, normal and ginseng, Poria cocos, the same usefulness of calamus such as Kaixin San (" prescriptions worth thousand gold "), if Fang Zhongzai adds fushen, are not namely forgotten fall apart (" Standards of Diagnosis and Treatment ")." book on Chinese herbal medicine just ": polygala root, the wholwe-hearted kidney of merit is therefore but relieving palpitation is only frightened, the peace that exorcises evil spirits dream, Yang strengthening and life essence tonifying, strong will power-assisted.With its gas lift, therefore same ginseng, Radix Glycyrrhizae, jujube kernel, the utmost point can be lifted to fall into and take the photograph essence, handing-over extreme misery
Contain the multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, synanthrin in the dandelion plant, the effects such as diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogic are arranged.Dandelion contains protein, fat, carbohydrate, trace element and vitamin etc. simultaneously, and abundant nutritive value is arranged, and is raw-eaten, stir-fry and eat, cook soup, is the plant of dietotherapeutic.Dandelion cures mainly the infection of the upper respiratory tract, eye conjunctivitis, mumps, hyperglycaemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, courage is assisted inflammation, acute appendicitis, urinary infection, pelvic infecton, carbuncle furuncle furunculosis, pharyngitis is controlled acute mastitis, adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infections.
The oldenlandia diffusa heat-clearing stasis of blood of faling apart, the carbuncle that disappears detoxifcation.Control ulcer sores, scrofula.Again can clearing lung-heat fire, purging the lung of pathogenic fire heat.Control the lung heat syndrome characterized by dyspnea, cough against uncomfortable in chest.Oldenlandia diffusa is the whole grass medicinal plant, has the effects such as clearing heat and detoxicating, inducing diuresis to reduce edema, promoting blood circulation and stopping pain, and medical science proves that again it has anticancer and protects the effect such as liver in recent years.
Earthworm: Compendium of Material Medica is referred to as to have clearing and activating the channels and collaterals, promoting blood circulation and removing blood stasis, prophylactic treatment cardiovascular and cerebrovascular disease effect.Earthworm is cold in nature distinguishes the flavor of into.Function: heat-clearing, flat liver, Zhichuan, logical Lip river.Cure mainly height fanatical dry, convulsion, headache due to pathogenic wind-heat, hot eyes, hemiplegia etc.Earthworm provides gets liquid the good effect that cloperastine is breathed heavily of deciding is arranged.
The oriental wormwood clearing heat and promoting diuresis; Removing jaundice.Cure mainly: jaundice, difficult urination, wet sore itch, infectious jaundice type hepatitis.Pharmaceutical research has cholagogic, and liver function protecting is analgesic, anti-inflammatory, and reducing blood lipid, the effects such as hat are expanded in step-down, and infusion, ethanol, infusion, volatile oil and 6,7-escoparone all have hypotensive activity.Latter 0.4-10mg/kg intravenous injection or duodenal administration all have remarkable blood pressure lowering effect to general anesthesia or local anaesthesia rat, cat and rabbit.This effect by hexamethonium and atropine blocking-up, is not strengthened by phentolamine, can not be to adrenolytic boosting.Do vertebral artery when injection with 1/50-1/10 intravenous injection dosage, hypotensive intensity and full dose point out that its hypotensive activity may be for central about equally.6,7-escoparone has humidification to the convergent force of the rabbit heart in place and the cat heart.Escoparone has significant step-down and peaceful effect.Hypotensive effect is stronger than ethyldopa, and dog intravenous injection 10mg/kg can make blood pressure drops 58.6%, 160 minutes duration, and under same dosage, ethyldopa blood pressure drops 12.4%, 120 minutes duration.Escoparone also has diuresis.
The specific embodiment of the invention 1:
Select materials: will gather first on the mulberry tree without the 2-3 position leaf of disease and pest, elutriation is dried, and puts in order overlapping.
Qie Ye: cut petiole, mulberry leaf are cut into filament, 2-4 centimetre of wide being advisable cut meticulously, easily becomes broken end during stranding, cuts excessively slightly, is difficult for rubbing the leaf juice of mulberry leaf.
Complete: the filament mulberry leaf are put in people's frying pan, and heating completes, first temperature fire heating, and the temperature that slowly raises is kneaded when the leaf look becomes strong green.Note grasping the size of the duration and degree of heating, heat color is too large, and the mulberry leaf silk easily becomes broken end, and heat color is too light, is difficult to remove the mulberry leaf herbaceous taste.
Knead, cure: in large iron pan, carrying out, backward downwards first on, firmly want evenly, when filament leaf bar rope is tighter, becomes and then cure when dark brown; Put into 80-100 ℃ baking machine turning in and fry moulding in 30-45 minute, make the mulberry leaf major ingredient.
The Chinese medicine auxiliary material is granulated: with the bulk drug bark of eucommia of Chinese medicine auxiliary material, and Radix Angelicae Sinensis, Poria cocos, Chinese violet, Radix Codonopsis, polygala root, gynostemma pentaphylla, Ligusticum wallichii, radix polygonati officinalis, peach kernel, root tuber of aromatic turmeric, the dried rhizome of rehmannia, the root of Dahurain angelica, earthworm, the red sage root, dandelion, the fruit of glossy privet, oldenlandia diffusa, the agent of root of herbaceous peony granulation.
Pack: with the above-mentioned granule that makes, the mulberry leaf good with aforementioned airing mix, and mix by 1: 10 weight portion, then can pack product, can be distributed into the little tea bag of 10-15 gram, also can integral body be mixed into the bag sale.In the described Mulberry-leaf Tea, the weight proportion of mulberry leaf major ingredient and Chinese medicine auxiliary material also can for, 6: 1,7: 1,9: 1,12: 1,14: 1,18: 1 or 20: 1.
The specific embodiment of the invention 2:
Pluck the 30Kg mulberry leaf, will gather first on the mulberry tree without the 2-3 position leaf of disease and pest, elutriation is dried, and puts in order overlapping.Cut petiole, mulberry leaf are cut into filament, 2-4 centimetre of wide being advisable cut meticulously, easily becomes broken end during stranding, cuts excessively slightly, is difficult for rubbing the leaf juice of mulberry leaf.Put in people's frying pan being cut into the filament mulberry leaf, heating completes, first temperature fire heating, and the temperature that slowly raises is kneaded when the leaf look becomes strong green.Note grasping the size of the duration and degree of heating, heat color is too large, and the mulberry leaf silk easily becomes broken end, and heat color is too light, is difficult to remove the mulberry leaf herbaceous taste.The filament mulberry leaf that obtain are placed in large iron pan are carrying out, backward downwards first on, firmly want evenly, when filament leaf bar rope is tighter, becomes and then cure when dark brown; Put into 80-100 ℃ baking machine turning in and fry moulding in 30-45 minute, become the mulberry leaf major ingredient.
With the bulk drug bark of eucommia 200g of Chinese medicine auxiliary material, Radix Angelicae Sinensis 150g, Poria cocos 120g, Chinese violet 130g, Radix Codonopsis 150g, polygala root 110g, gynostemma pentaphylla 130g, Ligusticum wallichii 140g, radix polygonati officinalis 120g, peach kernel 120g, root tuber of aromatic turmeric 110g, dried rhizome of rehmannia 150g, root of Dahurain angelica 130g, earthworm 120g, red sage root 110g, dandelion 120g, fruit of glossy privet 110g, oldenlandia diffusa 120g, root of herbaceous peony 150g drops in the multi-function extractor, adding for the first time 5-10 times of water gaging decocted 1-2 hour, add for the second time 4-8 times of water gaging and decocted 1-2 hour, merge decocting liquid twice, filter to get filtrate; Leave standstill, remove supernatant, heating is concentrated into pasty state, adds starch, then puts into granulator and makes 1-2 centimetre of granule.Then the Mulberry-leaf Tea finished product that obtains with above-mentioned steps by 1: 10 weight portion mix (weight proportion of mulberry leaf major ingredient and Chinese medicine auxiliary material also can for, 6: 1,7: 1,9: 1,12: 1,14: 1,18: 1 or 20: 1), be distributed into the little tea bag that 10-15 restrains, also can integral body be mixed into the bag sale.Can be distributed into the little tea bag of 10-15 gram, also can integral body be mixed into the bag sale.
The specific embodiment of the invention 3:
Pluck the 20Kg mulberry leaf, mulberry leaf are put into the clear water washing, dirty the getting final product of the floating ash of flush away do not rubbed energetically, and preferably every mulberry leaf are smooth, washed mulberry leaf are put on the bamboo mat ted, and note ventilating, and upset parches it naturally.Washed mulberry leaf are put on the bamboo mat ted, note ventilating, upset parches it naturally.In electric pot, complete, under 100 ℃, completed 30 minutes; Naturally, dry after mulberry leaf after completing are taken out, knead with hand, or put into large iron pan and carry out, backward downwards first on, firmly want evenly, when filament leaf bar rope is tighter, become the baking machine turning in stir-fry moulding in 30 minutes of putting into 120 ℃ when dark brown.The mulberry leaf that stir-fry are dried naturally, put into the fragrance extracting machine Titian 30 minutes, temperature is controlled in 80 ℃, naturally dries after taking out.The mulberry leaf that stir-fry are dried naturally, put into the fragrance extracting machine Titian 30 minutes, temperature is controlled in 100 ℃, naturally dries after taking out.With all the other raw material bark of eucommia 180g, Radix Angelicae Sinensis 150g, Poria cocos 120g, Chinese violet 130g, Radix Codonopsis 150g, polygala root 110g, gynostemma pentaphylla 140g, Ligusticum wallichii 140g, radix polygonati officinalis 130g, peach kernel 120g, root tuber of aromatic turmeric 110g, dried rhizome of rehmannia 150g, root of Dahurain angelica 130g, earthworm 110g, red sage root 110g, dandelion 120g, fruit of glossy privet 1210g, oldenlandia diffusa 120g, root of herbaceous peony 130g puts it in 10 times of water gagings and soaks.Drop into multi-function extractor and extract twice, add 8-10 times of water gaging for the first time and decocted 1-2 hour, add 4-8 times of water gaging for the second time and decocted 1-2 hour, merge decocting liquid twice, filter to get filtrate; Heating is concentrated into pasty state, cools off after putting into 80 ℃ of oven dry of baking oven, adds to enter in the granulator behind the starch to granulate.Then the Mulberry-leaf Tea finished product that obtains with above-mentioned steps mixes by 1: 10 weight portion, is distributed into the little tea bag of 10-15 gram, also can integral body be mixed into bag and sell.Can be distributed into the little tea bag of 10-15 gram, also can integral body be mixed into the bag sale.
The pharmacology toxicity test
Experimental example 1: acute toxicity test of the present invention
One, test material:
Animal: Kunming mouse, body weight 18-25g, male and female half and half, Qingdao Agricultural University's biology laboratory breeding.Medicine: Mulberry-leaf Tea solution of the present invention: 15 gram tea bags, add 200 milliliters of boiling water, steeped cool use of drying in the air 20 minutes.
Two, method:
1, LD50 calculates: adopt the improvement karber's method, mouse is divided into 5 groups at random, and 10 every group, male and female half and half, with adding distil water dissolving of the present invention, be made into Cmax, by the administration of the maximum permission capacity of mouse, institute is followed successively by 18 to dosage by the crude drug amount, 14.4,11.5,9.2,7.4 (g.kg
-1), in animal fasting (can't help water) after 18 hours, at twice administration (interval half an hour) in a day, each 0.5ml observes the animal dead situation.
2, maximum tolerated dose is measured (MTD value): get 20 of mouse, each 10 of male and female.With adding distil water of the present invention dissolving, be made into maximum concentration, by the maximal tolerance dose of animal, fill with injection and to feed device and can twitch and be as the criterion.In animal fasting (can't help water) after 18 hours, at twice administration (interval half an hour) in a day, each 0.5ml (every ml contains crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption.Continuous Observation is 7 days after the administration.
Three, result of the test:
In LD50 calculates when giving mouse with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, namely do not measure LD50, ask only maximum tolerated dose, in 7 day observation period, its appetite of animal, activity, hair color, the state of mind etc. are all normal, grow normally, there are no death.Namely select 300 times of doses that are equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD＞18g/Kg.d.
Experimental example 2: the result of the test of acute toxicity and long term toxicity
Acute toxicity test: give Mulberry-leaf Tea powder solution of the present invention (after Mulberry-leaf Tea of the present invention breaks into fine powder with pulverizer by the disposable gavage of small white mouse, soluble in water), maximum concentration 35%, maximum gavage capacity 0.4ml/10g, dosage 14g/kg, Continuous Observation 7 days is not found any toxic reaction, because concentration and dosage can't increase, therefore fail to measure the LD50 of this medicine.Maximum tolerance determination: with maximum concentration, maximum gavage capacity, mice lavage administration 3 times, interval 5 hours, then Continuous Observation is 7 days, and none example is dead.Medicinal powder dosage is＞42g/kg. day, calculate the clinical consumption per day that is equivalent to be grown up by kg body weight 810 times.
Long term toxicity test: whether produce toxic reaction for observing long-term prescription, giving respectively rat the present invention raises and takes Mulberry-leaf Tea fine powder of the present invention (after Mulberry-leaf Tea of the present invention breaks into fine powder with pulverizer, mix in feed), by adult 170 times and 120 times of clinical consumption per day, give continuously and fed for 8 weeks, the behavior, feed, the body weight that have no rat occur unusual, with the control group ratio, routine blood test, hepatic and renal function, various important organs all change without unusual, in institute's dosage scope, have not found any toxicity of the present invention.By the acute and chronic toxicity test confirmation of animal, safe range of the present invention is larger, is a kind of safe and reliable health products.
The specific embodiment:
Choose three high crowds, be divided at random 2 groups, treatment group 40 examples, male 27 examples, women 13 examples; Age 47-76 year, average 61.5 years old; Most of hypertension, diabetic duration 5-20; Fasting blood-glucose is 8.60～25.82mmol/L, average 170/95 millimetres of mercury of blood pressure, control group 30 examples, male 18 examples, women 12 examples; Age 45-75 year, average 63.2 years old; Hypertension, diabetic duration 6-23; Fasting blood-glucose is 8.45～26.62mmol/L, and two groups of physical data of average 175/97 millimetres of mercury of blood pressure are learned processing by statistics, and difference there are no significant meaning (P＞0.05) has comparativity.
2 methods of treatments
2.1 Primary Care control group control blood sugar, OHA or insulin injection with glycemic control near normal level; Improve microcirculation and hemangiectasis medicine; Reasonable diet, moderate exercise is built up health.
2.2 treatment group in Primary Care, adopts oral the present invention to replace drinking water.Every day the 2-3 bag.
3. treatment results
Treatment results: drink of the present invention group and treat average limosis vein blood slurry blood sugar 3.7～6.1mmol/L, venous plasma blood sugar＜7.9mmol/L after the meal, average 137/90 millimetres of mercury of blood pressure; Do not drink of the present invention group of average limosis vein blood slurry blood sugar 4.8～7.3mmol/L, venous plasma blood sugar＜11.9mmol/L after the meal, average 151/92 millimetres of mercury of blood pressure, show and drink the effect that truly has the assistant hypoglycemic step-down of the present invention, has good health-care effect, difference all has significant (P＜0.01), and gender's difference is little.
Claims (10)
1. a mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea is characterized in that, comprises mulberry leaf major ingredient and Chinese medicine auxiliary material; Wherein, the parts by weight of various bulk drugs are in the described Chinese medicine auxiliary material: 10～20 parts of the barks of eucommia, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts in Poria cocos, 10～20 parts of Chinese violets, 10～20 parts of Radix Codonopsis, 10～20 parts of polygala roots, 10～20 parts of gynostemma pentaphylla, 10～20 parts of Ligusticum wallichiis, 10～20 parts of radix polygonati officinalis, 10～20 parts in peach kernel, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts in the dried rhizome of rehmannia, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of earthworms, 10～20 parts of the reds sage root, 10～20 parts of dandelions, 10～20 parts of the fruit of glossy privets, 10～20 parts of oldenlandia diffusas, 10～20 parts of the root of herbaceous peonys.
2. described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 1 is characterized in that, the parts by weight of various bulk drugs are in the described Chinese medicine auxiliary material: 10～15 parts of the barks of eucommia, 10～15 parts of Radix Angelicae Sinensis, 10～15 parts in Poria cocos, 10～15 parts of Chinese violets, 10～15 parts of Radix Codonopsis, 10～15 parts of polygala roots, 10～15 parts of gynostemma pentaphylla, 10～15 parts of Ligusticum wallichiis, 10～15 parts of radix polygonati officinalis, 10～20 parts in peach kernel, 10～20 parts of root tubers of aromatic turmeric, 10～20 parts in the dried rhizome of rehmannia, 10～20 parts of the roots of Dahurain angelica, 10～20 parts of earthworms, 10～20 parts of the reds sage root, 10～20 parts of dandelions, 10～20 parts of the fruit of glossy privets, 10～20 parts of oldenlandia diffusas, 10～20 parts of the root of herbaceous peonys.
3. described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 1 is characterized in that, the parts by weight of various bulk drugs are in the described Chinese medicine auxiliary material: 10～20 parts of the barks of eucommia, 10～20 parts of Radix Angelicae Sinensis, 10～20 parts in Poria cocos, 10～20 parts of Chinese violets, 10～20 parts of Radix Codonopsis, 10～20 parts of polygala roots, 10～20 parts of gynostemma pentaphylla, 10～20 parts of Ligusticum wallichiis, 10～20 parts of radix polygonati officinalis, 10～15 parts in peach kernel, 10～15 parts of root tubers of aromatic turmeric, 10～15 parts in the dried rhizome of rehmannia, 10～15 parts of the roots of Dahurain angelica, 10～15 parts of earthworms, 10～15 parts of the reds sage root, 10～15 parts of dandelions, 10～15 parts of the fruit of glossy privets, 10～15 parts of oldenlandia diffusas, 10～15 parts of the root of herbaceous peonys.
4. one kind such as the preparation method of mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea as described in each in the claim 1～3, it is characterized in that, may further comprise the steps:
A. select mulberry leaf;
B. chopped leaves of mulberry leaf;
C. complete;
D. knead; Bake and bank up with earth, make the mulberry leaf major ingredient;
E. with Chinese medicine auxiliary material granulation;
F. with Chinese medicine granules of accessories obtained above agent and the mulberry leaf major ingredient of making by 8～15: pack after 1 part by weight mixes.
5. the preparation method of described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 4 is characterized in that: among the described step a, gather first on the mulberry tree without the 2-3 position mulberry leaf of disease and pest, elutriation is dried, and puts in order overlapping.
6. the preparation method of described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 4, it is characterized in that: among the described step b, cut petiole, mulberry leaf are cut into filament, 2-4 centimetre wide.
7. the preparation method of described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 4, it is characterized in that: among the described step c, the mulberry leaf filament is put into frying pan, heating completes, first slow fire heating, the temperature that slowly raises cools when the leaf look becomes strong green.
8. the preparation method of described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 4 is characterized in that: in the described steps d, the mulberry leaf spire after completing is being kneaded in large iron pan, on first downwards backward, firmly evenly, when filament leaf bar rope is tighter, becomes and then cure when dark brown; Put into 80-100 ℃ baking machine turning in and fry moulding in 30-45 minute, make the mulberry leaf major ingredient.
9. the preparation method of described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 4, it is characterized in that: among the described step e, described all the other bulk drugs are dropped in the multi-function extractor, adding for the first time weight portion 5-10 times of water gaging decocted 1-2 hour, adding for the second time weight portion 4-8 times of water gaging decocted 1-2 hour, merge decocting liquid twice, filter to get filtrate; Leave standstill, remove supernatant, heating is concentrated into pasty state, adds starch, then puts into granulator and makes 1-2 centimetre of particle.
10. the preparation method of described mulberry leaf blood fat-reducing blood pressure-decreasing health protection tea according to claim 4 is characterized in that: among the described step f, the mulberry leaf major ingredient that the Chinese medicine granules of accessories that makes and above-mentioned steps are made is by 1: 8～15 weight proportion, the moulding of pack packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013100084801A CN103027155A (en) | 2013-01-10 | 2013-01-10 | Mulberry leaf lipid-reducing pressure-reducing health-care tea and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2013100084801A CN103027155A (en) | 2013-01-10 | 2013-01-10 | Mulberry leaf lipid-reducing pressure-reducing health-care tea and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN103027155A true CN103027155A (en) | 2013-04-10 |
Family
ID=48014976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2013100084801A Pending CN103027155A (en) | 2013-01-10 | 2013-01-10 | Mulberry leaf lipid-reducing pressure-reducing health-care tea and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103027155A (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103380903A (en) * | 2013-06-29 | 2013-11-06 | 安徽皖山食品有限公司 | Chrysanthemum hypertension paste and preparation method thereof |
| CN103385320A (en) * | 2013-06-29 | 2013-11-13 | 于巧媛 | Hypolipemic healthy tea and preparation method thereof |
| CN103431109A (en) * | 2013-08-06 | 2013-12-11 | 北京绿源求证科技发展有限责任公司 | Heart-nourishing food health-preserving tea granule |
| CN104256017A (en) * | 2014-10-21 | 2015-01-07 | 叶青芝 | Healthcare mulberry leaf and apple peel tea and preparation method thereof |
| CN104336257A (en) * | 2014-10-28 | 2015-02-11 | 广西金昊生物科技有限公司 | Folium mori tea bag and preparation method thereof |
| CN104605070A (en) * | 2015-01-13 | 2015-05-13 | 陕西普田源农业发展有限公司 | Compound tea based on mulberry leaves and eucommia ulmoides oliver and preparation method of compound tea |
| CN104642659A (en) * | 2015-02-01 | 2015-05-27 | 顾明健 | Folium mori tea for reducing blood pressure |
| CN105285222A (en) * | 2015-10-12 | 2016-02-03 | 谢艳军 | Health-care beverage for the prevention and treatment of hyperlipidemia and preparation method thereof |
| CN105533056A (en) * | 2016-01-05 | 2016-05-04 | 刘华武 | Healthy tea with blood pressure reducing effect |
| CN108432913A (en) * | 2018-03-02 | 2018-08-24 | 合肥仙之峰农业科技有限公司 | A kind of antipyretic eliminating the phlegm green health tea beverage and preparation method thereof |
| CN113907231A (en) * | 2021-09-28 | 2022-01-11 | 广西壮族自治区蚕业技术推广站 | Preparation method of mulberry leaf biological novel beverage with weight-losing and toxin-expelling functions and product |
-
2013
- 2013-01-10 CN CN2013100084801A patent/CN103027155A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103380903A (en) * | 2013-06-29 | 2013-11-06 | 安徽皖山食品有限公司 | Chrysanthemum hypertension paste and preparation method thereof |
| CN103385320A (en) * | 2013-06-29 | 2013-11-13 | 于巧媛 | Hypolipemic healthy tea and preparation method thereof |
| CN103431109A (en) * | 2013-08-06 | 2013-12-11 | 北京绿源求证科技发展有限责任公司 | Heart-nourishing food health-preserving tea granule |
| CN104256017A (en) * | 2014-10-21 | 2015-01-07 | 叶青芝 | Healthcare mulberry leaf and apple peel tea and preparation method thereof |
| CN104336257A (en) * | 2014-10-28 | 2015-02-11 | 广西金昊生物科技有限公司 | Folium mori tea bag and preparation method thereof |
| CN104605070A (en) * | 2015-01-13 | 2015-05-13 | 陕西普田源农业发展有限公司 | Compound tea based on mulberry leaves and eucommia ulmoides oliver and preparation method of compound tea |
| CN104642659A (en) * | 2015-02-01 | 2015-05-27 | 顾明健 | Folium mori tea for reducing blood pressure |
| CN105285222A (en) * | 2015-10-12 | 2016-02-03 | 谢艳军 | Health-care beverage for the prevention and treatment of hyperlipidemia and preparation method thereof |
| CN105533056A (en) * | 2016-01-05 | 2016-05-04 | 刘华武 | Healthy tea with blood pressure reducing effect |
| CN108432913A (en) * | 2018-03-02 | 2018-08-24 | 合肥仙之峰农业科技有限公司 | A kind of antipyretic eliminating the phlegm green health tea beverage and preparation method thereof |
| CN113907231A (en) * | 2021-09-28 | 2022-01-11 | 广西壮族自治区蚕业技术推广站 | Preparation method of mulberry leaf biological novel beverage with weight-losing and toxin-expelling functions and product |
| CN113907231B (en) * | 2021-09-28 | 2024-03-29 | 广西壮族自治区蚕业技术推广站 | Preparation method of mulberry leaf biological beverage and product |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102988638B (en) | Cyclocarya paliurus blood-lipid and blood-sugar reducing health-care tea and preparation method thereof | |
| CN102160573B (en) | Milk shake for replacing meal and preparation method thereof | |
| CN102986887B (en) | Health maintenance flavor milk shake and preparation method thereof | |
| CN103053748B (en) | Kudzu vine root fat-reducing sugar-reducing health-care tea and preparation method thereof | |
| CN103027155A (en) | Mulberry leaf lipid-reducing pressure-reducing health-care tea and preparation method thereof | |
| CN104322617B (en) | Biscuit of a kind of auxiliary hyperglycemic and preparation method thereof | |
| CN103734424B (en) | A kind of bitter buckwheat Weight-reducing and lipid-lowering constipation-relieving tea and preparation method thereof | |
| CN103055259B (en) | A kind of Folium Lycii lowering blood-fat and reducing weight health tea and preparation method thereof | |
| CN103719497A (en) | Gynostemma pentaphylla fat-reducing and weight-losing health-care tea and preparation method thereof | |
| CN105454576A (en) | Jasmine-flower-comprising assorted Chinese herbal tea and preparation method thereof | |
| CN103005104A (en) | Boxthorn leaf traditional Chinese medicine health tea for preventing and curing lung-kidney yin deficiency and preparation method thereof | |
| CN104365943A (en) | Fructus sophorae tea with effect of reducing sugar and fat and preparation method thereof | |
| CN103719495B (en) | A kind of great burdock achene hypoglycemic health protection tea and preparation method thereof | |
| CN105124078A (en) | Gardenia blood-glucose-reducing and lipid-reducing healthcare tea and preparing method thereof | |
| CN102860390B (en) | Mulberry leaf weight-reducing tea and method for preparing same | |
| CN103749824A (en) | Gynostemma pentaphyllum health-care tea capable of lowering blood sugar and blood pressure and preparation method thereof | |
| CN103749819B (en) | Fructus Corni health protection tea of a kind of hypoglycemic and preparation method thereof | |
| CN104206595A (en) | Blood lipid and blood glucose reducing Chinese wolfberry root-bark health care tea and preparation method thereof | |
| CN104304602A (en) | Pagoda tree fruit tea capable of softening blood vessels and preparation method thereof | |
| CN104544084B (en) | A kind of health food for diabetics | |
| CN103783508A (en) | Buckwheat oral liquid for beauty treatment and freckle removal, and preparation method thereof | |
| CN106701410A (en) | Healthcare wine capable of strengthening stomach and tonifying qi and production method thereof | |
| CN106509209A (en) | Propolis health-care tea and preparation method thereof | |
| CN104856036A (en) | Health care medicated diet for treating iron-deficiency anemia and preparation method of health care medicated diet | |
| CN106860814B (en) | Health food composition for improving female frequent micturition and urinary incontinence and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130410 |