KR20100117514A - Composition for hair containing fermented extract - Google Patents

Abstract

PURPOSE: A composition containing fermentation for promoting hair growth is provided to strengthen hair follicle. CONSTITUTION: A composition for hair contains fermentation of rehmanniae Radix, ginseng, wolfiporia cocos, honey, green tea, swertia japonica, polygoni multiflori Radix and Glycine Semen nigra as an active ingredient. The fermentation is performed by yeast. The composition is used in the form of hair tonic, hair treatment, hair serum, hair shampoo, or hair lotion.

Description

Composition for hair containing fermented extract

The present invention relates to a composition for hair.

As the modern society tends to focus on beauty, many people of all ages, including men and women, use hair dyes and perm agents to satisfy their desire to express individuality. However, some of the sensitive scalp may cause irritation and inflammation such as itching and itching of the scalp due to chemical treatments such as staining and perm, and the irritation and inflammation lead to environmental hair loss. In addition, the hair and the scalp as a part of the body as the age of the skin as aging progresses, and will have a variety of changes and problems accordingly.

Therefore, there is a need for a composition that can alleviate scalp irritation and inflammation caused by the use of various hair dyes and permants, protect hair from harmful environments, strengthen hair roots, prevent hair loss, prevent aging of the scalp, and promote hair growth. It is emerging.

The present invention is to provide a composition for hair containing fermentation of fermented turmeric, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean to strengthen the hair root, promote hair growth and improve the scalp condition.

Hair composition according to one aspect of the present invention contains fermented product fermented with sulfur, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean as an active ingredient.

Hair composition according to an aspect of the present invention, fermented by turmeric, ginseng, bokyeong, honey, green tea, medicinal herbs, sewage and black bean as an active ingredient, compared to the composition containing only conventional extracts, hair root strengthening, Promotes hair growth and improves scalp. In addition, the composition strengthens weakened hair roots, nourishes the hair roots, and repairs damaged hair roots and scalp, thereby preventing hair loss and preventing hair aging. On the other hand, the composition does not show toxicity even at high concentrations can be used safely.

1 is a graph showing the Wnt signal transduction activation effect of the test substance in Test Example 1.
2 is a result of visually observing the dermal papilla cell proliferation effect of the test substance in Test Example 2.
3 is a graph comparing the papillary cell proliferation effect of the test substance in Test Example 2.

In the present specification, the term "hair" is a general term for body hair and hair, and may also be described as hair. The hair also includes both human and animal hair.

Hereinafter, the present invention will be described in more detail.

The present inventors have a fermentation product fermented with sulfuric acid, ginseng, bokyeong, honey, green tea, sugars, sewage and black bean has excellent hair root strengthening effect, hair growth effect and scalp improvement effect compared to the extract of the same ingredients, and toxic in the fermentation process It was found that this did not appear and the present invention was completed.

Thus, one aspect of the present invention provides a composition for hair containing fermented product fermented with Chihwang, ginseng, Bokryeong, honey, green tea, sugar, sewage and black bean as an active ingredient.

Rehmannia is a perennial medicinal plant of the Scrophulariaceae Rehmannia (Rehmannia glutinosa Liboschitz var. purpurea Makino), whose root is mainly used as a medicinal herb. It is called raw jihwang, dried one is called Gunjihwang, and steamed dried one is called Suhjihwang. Among them, Gujihwang is made of alcohol that is dipped 9 times after drying. Rehmanniamic has a warming property to supplement the blood and replenish the affection (精: basic substance for life and activity), which is effective in treating back pain and pain in the lower back and knees, dysmenorrhea and dizziness. have.

In one aspect of the present invention, the turmeric may include all parts of the turmeric, for example, the leaves, roots, stems, flowers or fruits of the turmeric. In another aspect of the present invention, the turmeric may include the root of the turmeric.

Ginseng Panax belonging to the family As a plant of the ginseng variety, ginseng root has long been used for medicinal purposes. The root of ginseng cultivated in Korea is Geun-geun root (肥大 根), which consists of one root and two to five root roots, and is pale yellow white. The number of roots varies depending on soil quality, transplantation method, fertilizer, and moisture, but it is a strong branching plant. The shape of the roots varies with age, and harvesting is usually done in 4-6 years. When ginseng is used as a cosmetic raw material, it is known to have various effects and effects such as skin cell regeneration and wrinkle improvement.

In one aspect of the invention, the ginseng may include all parts of the ginseng, for example, the leaves, roots, stems, flowers or fruits of ginseng. In another aspect of the present invention, the ginseng may include the root of ginseng.

Poria cocos is bokryeong (Poria with jannabi stools parasitic on the roots of pine Cocoa Wolf's fungus has been used as a tonic since ancient times, and is mostly used as a medicine by almost removing its outer layer. The results of pharmacological experiments have been shown to act as a diuretic effect, lowering blood sugar, sedation, etc., and also known to be immune-activated. In addition, the spleen is swelling (虛) is used when the body swelling and Damyeong disease. In addition, it is used for revenge, diarrhea, forgetfulness and sleep disorders. It is known to have an excellent effect on diseases such as stomach, liver, interest, kidney, etc., and is used as a medicine for the treatment of a weak person or a chronic gastrointestinal patient after suffering a disease. It is also known to be effective against all sexually transmitted diseases and gynecological diseases, as well as the toxic diseases of men and women.

In one aspect of the present invention, the Bokryeong is a Bokryeong with a Jangnabi stool parasitic in the root of the pine ( Poria cocos Wolf's fungal nucleus, which may include those made by almost removing the outer layer.

Honey contains honey and molasses. Honey contains comprehensive nutritional ingredients and enzymes such as vitamins, proteins, minerals, aromatics, and amino acids that are unique to pollen, and is excellent in fatigue recovery effect from glucose and fructose. Honey, which is composed mainly of glucose and fructose, is absorbed directly by the body's barrier and stored in the liver after it becomes a glycogen. Glucose is primarily burned by muscle cells in the body to generate the energy needed to sustain life. Honey contains most of the minerals needed by humans to facilitate vital physiological functions in the body and to complete bone tissue development.

In one aspect of the invention, the honey includes all honey that can be commonly referred to as honey. In another aspect of the invention, the honey comprises honey or molasses. In another aspect of the invention, the honey comprises honey.

Green tea / Thea sinensis Linnaeus) is an evergreen tree or shrub belonging to Theaceae, from which the green tea, black tea, oolong tea, etc. are produced. Green tea is obtained by steaming tea leaves, stems or flowers to inactivate oxidation-related enzymes and to keep the polyphenol component stable. Polyphenols found in green tea are found to be flavonol and catechin, and are known to have various effects such as antioxidant, anticancer, anti-inflammatory and antibacterial properties, and are widely used as cosmetic raw materials.

In one aspect of the invention, the green tea may include all parts of the green tea, for example, the leaves, roots, stems, flowers or fruit of the green tea. In another aspect of the present invention, the green tea includes leaves, stems or flowers of green tea.

Glucose is Swertia japonica Makino) means an outpost and has been used medicinally for a long time. It is one year or month of the year, which belongs to the genus Bitterweed, and grows on sunny hills, hillsides, meadows, and bright pine forests. Up to a year of winter, only two or four rocket-shaped root leaves are elliptical and pointed, but they grow up to about 5 to 20 centimeters high in spring with a purple stem. In autumn, white flowers with 5 petals bloom and wither when they bear fruit. Fruits are capsules, lanceolate, seeds very small. The genus of bitter grass is distributed around the world, and many species are growing in Korea. The kinds of bitter grass that grow wild in Korea include dog bitter grass, bitter grass, purple bitter grass, white purple bitter grass, four bitter grass, chickweed bitter grass, and big leaf bitter grass. It is effective in protecting skin, antipyretic, strengthening stomach, moisturizing, indigestion, loss of appetite, gastritis, jaundice, stomachache, eye disease, toothache, ulcer, acute bacterial dysentery, abdominal pain, liver protection, osteomyelitis, infection, conjunctivitis Known.

In one aspect of the present invention, the drug may include all the parts of the drug, for example, the leaves, roots, stems, flowers or fruits of the drug. In another aspect of the present invention, the drug comprises a leaf, fruit or flower of the drug.

Polygonum multiflorum is a vine perennial genus belonging to the Polygonaceae, and contains roots such as Chrysophanol, Emodin, and lecithin, which are oxymethylanthraquinone derivatives. Sewage is effective in preventing skin aging through antioxidant and astringent effects.

In one aspect of the invention, the sewage may include all parts of the sewage, for example, the leaves, roots, stems, flowers or fruits of the sewage. In another aspect of the invention, the sewage includes the roots of sewage.

Black Beans are Beans and Glycine As a max variety, it is widely grown as an edible crop. Fruits are edible, streaked, flat oval, with 1-7 seeds per one. When fully cooked, the pod bursts, dispersing the seeds. Seeds vary depending on the variety in round, flat and round shape. This is known to have a moisturizing effect, soothing itching and hair loss prevention effect on dry skin. One black soybean contains 40% protein, 35% carbohydrate (25% dietary fiber, 10% oligosaccharide), 20% lipid, 5% vitamin, anthocyanin, calcium, lecithin and isoflavones. Soy protein, anthocyanins, and vitamins have excellent effects on preventing aging by promoting blood circulation and preventing cell damage. Dark bean contains ingredients that facilitate the circulation of peripheral blood vessels, and vitamin E or unsaturated fatty acids of the black bean expand blood vessels to facilitate blood circulation. It is known that anthocyanin, a black pigment component of black bean skin, acts as a major potency ingredient.

In one aspect of the invention, the black bean may include both legumes and fruits that can be generally classified as black beans.

The above sulfur, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean may generally be used as a medicinal herb, more specifically as a herbal medicine.

As used herein, the term "fermentation" refers to a process in which microorganisms decompose organic materials using enzymes thereof.

In one aspect of the present invention, the composition may contain fermented products fermented with sulfur, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean as an active ingredient. In another aspect of the present invention, the composition may contain fermented filtrate, fermented and filtered fermented filtrate, ginseng, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean as an active ingredient.

In one aspect of the invention, the fermentation may be made by a conventional fermentation method.

In one aspect of the invention, the fermentation may be made by a microorganism generally used for fermentation. In another aspect of the invention, the fermentation may be made by non-pathogenic microorganisms. In another aspect of the invention, the fermentation may be made by yeast. In another aspect of the invention, the fermentation may be made by dry yeast.

Wnt signaling is a signaling process that is very important for the normal development of an individual by determining the differentiation fate of cells during development. Wnt signaling also maintains homeostasis by acting as a regulator of cell proliferation and differentiation after development. Wnt signaling induces the formation of hair follicles in embryonic embryos and, after birth, regulates hair stem cells and hair cycles to induce the production of new hair. Therefore, when the Wnt signaling process is activated, the anagen phase of hair follicles is induced, thereby strengthening the hair root.

In one aspect of the present invention, the hair composition containing the fermented product of the sulfuric acid, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean as an active ingredient to activate the Wnt signaling process to strengthen the hair root, scalp Improves hair growth, promotes hair growth, and prevents hair aging.

Dermal papilla cells (DPCs) are cells located at the base of hair follicles, and are responsible for hair growth and hair follicle cycle control by supplying oxygen and nutrients to the cells constituting hair follicles. Therefore, promoting the growth of papillary cells can make hair healthy, promote hair growth, and prevent hair loss.

In one aspect of the present invention, the hair composition containing a fermented product of fermented yolk, ginseng, bokyeong, honey, green tea, sugar, sewage and soybeans as an active ingredient has a health effect to promote the growth of dermal papilla cells Can promote hair growth, and prevent hair loss.

In one aspect of the invention, the weight ratio of the sulfuric acid, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean is 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5-25.0: May be 12.5-25.0. In another aspect of the invention, the weight ratio of the sulfuric acid, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean is 15 to 20: 15 to 20: 15 to 20: 15 to 20: 15 to 20: 15 to 20 : 15-20: May be 15-20. In another aspect of the invention, the weight ratio of the sulfuric acid, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean is 1 ~ 2: 1 ~ 2: 1 ~ 2: 1 ~ 2: 1 ~ 2: 1 ~ 2: 1 to 2: 1 to 2. In the above weight ratio, not only is it appropriate to exhibit the intended effect of the present invention, synergism occurs, and the stability and safety of the composition can be satisfied, and the cost-effectiveness can be appropriate.

In one aspect of the present invention, the fermented fermentation of the sulfuric acid, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean may be contained in 0.01 to 10.0% by weight relative to the total weight of the composition. In another aspect of the invention, the fermentation may be contained in 0.1 to 7.0% by weight based on the total weight of the composition. In another aspect of the invention, the fermentation may be contained in 1.0 to 5.0% by weight relative to the total weight of the composition. When used in the above range, it is not only suitable to exhibit the intended effect of the present invention, but also satisfies both the stability and safety of the composition, and may be appropriate in terms of cost-effectiveness. More specifically, when the fermentation is more than 10.0% by weight may affect the usability and antiseptic power of the composition.

In one aspect of the invention the hair composition may be a cosmetic composition. In another aspect of the present invention, the hair composition may have a formulation such as hair tonic, hair nourishing cosmetics, hair essence, hair serum, scalp treatment, hair treatment, hair conditioner, hair shampoo or hair lotion, It is not limited.

In addition, in each formulation, other ingredients in addition to the above-mentioned active ingredient can be appropriately selected and blended by those skilled in the art without difficulty depending on the type of formulation or the purpose of use.

For example, the hair shampoo composition according to one aspect of the present invention may be used by adding an appropriate component according to the kind. Specifically, synthetic surfactants and preservatives, thickeners and viscosity modifiers, pH adjusters, flavorings, dyes, hair conditioning agents or water which are conventional cleaning ingredients may be included.

In one aspect of the invention, the synthetic surfactant may be selected from anionic, amphoteric and nonionic surfactants and may be used alone or in combination. In addition, the synthetic surfactant may be contained in an amount of 10 to 70% by weight, preferably 10 to 30% by weight, based on the total weight of the composition.

As the synthetic anionic surfactant, alkyl or alkyl ether sulfate may be used, and specific examples thereof include sodium lauryl sulfate, lauryl ammonium sulfate, lauryl sulfate triethanolamine, polyoxyethylene lauryl sulfate or polyoxyethylene lauryl ammonium sulfate, and the like. Can be mentioned.

As the synthetic amphoteric surfactant, alkyl betaine or alkyl amidopropyl betaine may be used, and specific examples thereof include cocodimethyl carboxymethyl betaine, lauryldimethyl carboxymethyl betaine, lauryldimethyl alpha-carboxyethyl betaine and cetyl. Dimethyl carboxymethyl betaine, cocamidopropyl betaine, etc. are mentioned.

Alkanol amide or amine oxide may be used as the synthetic nonionic surfactant, and specific examples thereof include lauryl diethyl amine oxide, palm oil alkyldimethyl amine oxide, lauric acid diethanolamide, palm oil fatty acid diethanolamide or palm oil fatty acid mono Ethanolamide, and the like.

Preservatives may be used by mixing one or more selected from the group consisting of methyl paraoxybenzoate, propyl paraoxybenzoate, sodium benzoate, methylchloroisothiazolinone, methylisothiazolinone and sodium benzoate.

As the viscosity modifier, a coamide amide (CME), a coamide amide (CDE), sodium chloride, or the like, which is an amide nonionic surfactant, may be used.

As the pH adjusting agent, sodium phosphate, disodium phosphate, citric acid or sodium citrate can be used.

As a hair conditioning agent, dimethicone base, cationic polymer, etc. can be used individually or in mixture of 2 or more types.

The hair conditioner composition according to one aspect of the present invention may be used by adding an appropriate component depending on the kind. Specifically, the conventional conditioner components may contain cationic surfactants, tertiary amidoamines, quaternary ammonium compounds, high melting point compounds, and silicone compounds, and as optional ingredients, preservatives, thickeners, viscosity regulators, pH regulators, and perfumes. And the like.

In the hair conditioner composition according to one aspect of the present invention, as a tertiary amidoamine as a cationic surfactant, cocaamidopropyl dimethylamine, stearamidopropyl dimethylamine, beheniramidopropyl dimethylamine, oleamido Propyl dimethylamine or isostearamidopropyl dimethylamine and the like can be used. The amines can also be neutralized with acids such as L-glutamic acid, lactic acid, hydrochloric acid, malic acid, succinic acid, acetic acid, fumaric acid, citric acid, EDTA, etc. The quaternary ammonium compound may be alkyl (C14-22) trimethyl ammonium chloride, dialkyl (C14-22) dimethyl ammonium chloride, hydrogenated tallow alkyl trimethyl ammonium chloride or ditallow alkyl dimethyl ammonium chloride. Cationic surfactants may be contained alone or in mixture of two or more, in an amount of 1 to 30% by weight, preferably 5 to 20% by weight based on the total weight of the total composition.

As the high melting point compound, a compound consisting of fatty alcohols, fatty acids, fatty alcohol derivatives, hydrocarbons and mixtures thereof can be used, and specific examples thereof include cetyl alcohol, stearyl alcohol, cetostearyl alcohol, and the like. In addition, the high melting point compound may be contained in an amount of 1 to 10% by weight based on the total weight of the composition.

As the silicone compound, polyalkylsiloxane-based, polyarylsiloxane-based, polyalkylarylsiloxane-based, polyethersiloxane copolymers and mixtures thereof, cyclopolysiloxanes and their alkyl amino substituted compounds, amodimethicone and the like can be used. It may be contained in an amount of 1 to 10% by weight based on the weight.

Preservatives may be used by mixing one or more selected from the group consisting of methyl paraoxybenzoate, propyl paraoxybenzoate, sodium benzoate, methylchloroisothiazolinone, methylisothiazolinone and sodium benzoate.

As the pH adjusting agent, sodium phosphate, disodium phosphate, citric acid or sodium citrate can be used.

Hereinafter, the structure and effect of the present invention will be described in more detail with reference to Examples, Comparative Examples and Test Examples. However, these examples, comparative examples and test examples are provided only for the purpose of illustration to help the understanding of the present invention, and the scope and scope of the present invention is not limited by the following examples, comparative examples and test examples.

[Examples 1-3 and Comparative Examples 1-4]

Fermented products may be prepared by the following method. First, Chihwang, Ginseng, Bokryeong, Green Tea, Dangjak, Hasao, and Black Beans are selected and seasoned according to the theft of herbal medicines described in the herbal medicine standard of Korean Pharmacopoeia. Each of the above-mentioned powdered ingredients is 800g, 400g ginseng, 600g, 600g green tea, 600g green tea, 400g sugar, 600g sewage, 400g of black bean, 400g honey, put into a fermentor with honey 400g and purified water 15kg and dry yeast 100g 24 hours at 25 ℃ Political cultivation After the incubation is completed, each component is first removed, and heat treatment (80-90 ° C., 30 minutes) is performed for extraction and deactivation (inactivation) of active ingredients of the cultured yeast, followed by diatomaceous earth filtration and about 8 kg of yeast fermented product. Get The fermented yeast fermented with diatomaceous earth filtration is mixed with 8kg and 136kg of ionized water. A solution of a phenonip dissolved in 1,3-butylene glycol is mixed and stirred. After pre-filtering with a 1.0 μm filter, micro-filtering with a 0.45 μm filter yields about 150 kg of yeast fermentation filtrate. The appearance of the yeast fermentation filtrate is pale yellow liquid and has a specific odor.

To the compositions of Table 1 to Examples 1 to 3 and Comparative Examples 1 to 4 were prepared according to the above method. Examples 1 to 3 contain 1.0%, 5.0%, and 10.0% of fermented products of fermented yeast, ginseng, bokyeong, honey, green tea, sugar, sewage, and black bean with yeast, respectively. Comparative Example 1 is a control that contains nothing, Comparative Examples 2 to 4 are the same composition as Examples 1 to 3, respectively, but contain extract extracted in a conventional manner without yeast fermentation. The fermented products and extracts were purchased from ActiveOn . In Table 1, the content ratio (%) means the content of each substance (w / v) with respect to the cell culture medium volume.

Yogurt / Ginseng / Bukryeong / Honey / Green Tea / Drugs Chihwang / Ginseng / Bukryeong / Honey / Green Tea / Drugs / Sewage / Brown Bean Extract Example 1 1.0% - Example 2 5.0% - Example 3 10.0% - Comparative Example 1 - - Comparative Example 2 - 1.0% Comparative Example 3 - 5.0% Comparative Example 4 - 10.0%

Test Example 1 Evaluation of Hair Root Strengthening Efficacy

Wnt signaling activity was measured to evaluate hair root strengthening efficacy. Specific experimental methods and cell culture for the experiment are as follows. C3H / 10T 1/2 (ACTT) cells (mouse embryonic fibroblast) obtained from ATCC, 10% Fetal Bovine Serum, 100 units / ml penicillin-streptomycin (penicillin-streptomycin), MEM-α (Minimum Essential Medium-α, GIBCO) containing 0.5% Non-essential amino acid (NEAA), 37 ° C, 5% CO ₂ Incubated at.

Plasmid transfection was performed using TOP-Luc plasmid (Invitrogen, Inc.) and β-gal plasmid to monitor the activation of Wnt signaling. Transfection was performed using Lipofectamine 2000 (Invitrogen) and proceeded with reference to the experimental method provided by the manufacturer. Briefly, C3H cells were dispensed in 24 wells at a concentration of 2 × 10 ⁴ cells / well and incubated overnight in an incubator. Exchange the culture medium with penicillin-streptomycin-free medium, mix 1 μg of plasmid with 6 μl of Lipo2000 in Opti-MEM (Gibco) to form a DNA-Lipo complex, and then sprinkle on the cells. The plasmid was introduced into the cell in a manner. Four to six hours after the introduction of the plasmid, the cells were washed twice with PBS and replaced with the original culture medium.

Wnt signaling activity was measured by measuring the activity of luciferase. Plasmids were introduced into the cells, stabilized by incubation for 24 hours, and then treated with Comparative Examples 1 and 2 and Example 1 and incubated for another 24 hours. After incubation, the cells were washed twice with cold PBS, and the cells were destroyed by treating the cells with reporter lysis buffer (Promega) for 15 minutes. The obtained cell eluate was transferred to a micro tube and centrifuged at 12,000 rpm for 3 minutes at 4 ° C. to separate cell residues, thereby obtaining pure cell eluate.

Each Wnt signaling activity was evaluated by mixing Luciferase substrate (Promega) in the cell lysate at a 4: 1 ratio and measuring the amount of light emitted by the luminometer. In addition, in order to correct the difference according to the degree of plasmid introduction, the cell eluate was treated with the same amount of 2X β-galactosidase enzyme assay buffer (Promega) and reacted at 37 ° C. for one hour. By measuring the absorbance at 420 nm wavelength, β-galactosidase activity of each test substance was compared together. The Wnt signaling activity of each test substance was divided by the activity of each β-galactosidase to correct the difference according to the degree of plasmid introduction, and the final value was derived by statistical processing of the correction values. The results are shown in FIG.

As can be seen in Figure 1, when treating Comparative Example 2 containing only the extract that has not been fermented Example 1 compared with the case of treating Example 1 containing a fermentation product fermented with yeast material of the same composition It can be seen that it shows a much better Wnt signaling activity than Comparative Example 2.

As a result, the fermented product prepared through the fermentation exhibited better Wnt signaling activity than the extract extracted in the conventional manner, and it was confirmed that the effect of strengthening the hair root was more excellent.

[Test Example 2] Evaluation of the effect of breast papilla growth

Examples 2 and 3 and Comparative Examples 1, 3 and 4 were treated with dermal papilla cells (Unilever company, Wendy Fishell) to evaluate the degree of proliferation of dermal papilla cells (DPC) and BrdU. (bromdeoxyuridine) assay was performed. 10% FBS was treated as a positive control. The results of the observation with the naked eye are shown in FIG. 2, and each cell proliferation degree is shown in FIG. 3 when Comparative Example 1 is 100.

As can be seen in Figures 2 and 3, Comparative Examples 3 and 4 inhibited cell proliferation compared to Comparative Example 1 without adding anything, while Examples 2 and 3 both showed excellent dermal papilla growth effect, even at 10% concentration No cytotoxicity was observed. Therefore, the fermented product prepared through fermentation has an excellent effect of promoting hair growth by promoting dermal papilla cell proliferation, and does not show cytotoxicity even at high concentrations.

[Example 4 and Comparative Examples 5 to 6]

According to the conventional shampoo preparation method, the shampoo formulations of Example 4 and Comparative Examples 5 to 6 having the compositions of Table 2 were prepared. Example 4 contained the fermented product of Example 1, Comparative Example 5 did not contain any extracts and fermented products, Comparative Example 6 contained the unfermented extract of Comparative Example 2.

 Comparative Example 5 (wt%) Comparative Example 6 (weight) Example 4 (% by weight) Ammonium Lauryl Sulfate / Ammonium Laures Sulfate 16 16 16 Trihydroxystearin 0.3 0.3 0.3 Cetyl alcohol 0.6 0.6 0.6 Coca MIDA 1.0 1.0 1.0 Guarhydroxytrimonium chloride 0.2 0.2 0.2 Spices 1.0 1.0 1.0 antiseptic 0.03 0.03 0.03 Citric acid 0.05 0.05 0.05 Example 1 - - 1.0 Comparative Example 2 - 1.0 - Purified water To 100 To 100 To 100

[Test Example 3] Use Quality Test

After the shampoos of Example 4 and Comparative Examples 5 to 6 were used daily for two weeks for a panel consisting of 10 women aged 20 to 30 years, the following questionnaire items were scored 7-point scale (higher scores). The quality of use was assessed in such a way as to be excellent). The results are shown in Table 3 below.

Survey item Comparative Example 5 Comparative Example 6 Example 4 Bubble is good and feels good 5.4 5.5 5.5 Feels good when rinsing and fingers pass well 5.6 5.8 5.7 Easy to comb and soft when semi-dry 5.4 5.7 5.6 Easy to care for hair after drying 5.6 5.7 5.8 After drying, you can feel the freshness of the scalp and hair root area. 5.1 6.0 6.2 After two weeks, you can feel the richness of your hair. 5.3 6.0 6.1

As can be seen from the results of Table 3, the use of Example 4 containing fermented products is more excellent in the items of freshness of hair root and scalp and hair abundance after 2 weeks compared with the case of using Comparative Examples 5 to 6 The results were shown. Therefore, it can be seen that when it contains a fermentation product according to one aspect of the present invention, it is possible to provide a composition that can impart superior hair root and scalp freshness and hair abundance than those containing extracts of the same ingredient.

Claims (7)

A composition for hair comprising, as an active ingredient, a fermented product obtained by fermenting ginseng, ginseng, bamboo, honey, green tea, licorice, The method of claim 1,
The fermentation is a composition for hair, characterized in that made by yeast. The method according to claim 1 or 2,
The composition is a composition for hair, characterized in that the composition for strengthening the hair root. The method according to claim 1 or 2,
Wherein the composition is a composition for promoting hair growth. The method according to claim 1 or 2,
The weight ratio of the above sulfuric acid, ginseng, bokyeong, honey, green tea, sugar, sewage and black bean is 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0: 12.5 ~ 25.0 Hair composition, characterized in that. The method according to claim 1 or 2,
Wherein the fermented product is contained in an amount of 0.01 to 10.0% by weight based on the total weight of the composition. The method according to claim 1 or 2,
The composition is hair tonic, hair nourishing cosmetics, hair essence, hair serum, scalp treatment, hair treatment, hair conditioner, hair shampoo or hair lotion, characterized in that the hair cosmetic composition is formulated as a hair composition.

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