KR20100055464A - 오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 - Google Patents

오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 Download PDF

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KR20100055464A
KR20100055464A KR1020107005493A KR20107005493A KR20100055464A KR 20100055464 A KR20100055464 A KR 20100055464A KR 1020107005493 A KR1020107005493 A KR 1020107005493A KR 20107005493 A KR20107005493 A KR 20107005493A KR 20100055464 A KR20100055464 A KR 20100055464A
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South Korea
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methyl
thiazole
amino
carboxylic acid
carbonyl
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Korean (ko)
Inventor
아메드 애자위
크리슈토프 보쓰
마르쿠스 구데
랄프 코베르슈타인
띠에리 시페랑
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액테리온 파마슈티칼 리미티드
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Publication of KR20100055464A publication Critical patent/KR20100055464A/ko
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    • C—CHEMISTRY; METALLURGY
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
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    • C—CHEMISTRY; METALLURGY
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    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
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    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
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    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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KR1020107005493A 2007-08-15 2008-08-14 오렉신 길항제로서의 1,2-디아미도-에틸렌 유도체 Withdrawn KR20100055464A (ko)

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IB2007053249 2007-08-15
WOPCT/IB2007/053249 2007-08-15

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KR20100055464A true KR20100055464A (ko) 2010-05-26

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US (1) US20110263662A1 (cg-RX-API-DMAC7.html)
EP (1) EP2188282B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010536740A (cg-RX-API-DMAC7.html)
KR (1) KR20100055464A (cg-RX-API-DMAC7.html)
CN (1) CN101778846B (cg-RX-API-DMAC7.html)
AU (1) AU2008288151A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0815079A2 (cg-RX-API-DMAC7.html)
CA (1) CA2694993A1 (cg-RX-API-DMAC7.html)
ES (1) ES2400830T3 (cg-RX-API-DMAC7.html)
MX (1) MX2010001575A (cg-RX-API-DMAC7.html)
RU (1) RU2010109455A (cg-RX-API-DMAC7.html)
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160077216A (ko) * 2013-11-19 2016-07-01 액테리온 파마슈티칼 리미티드 트리시클릭 피페리딘 화합물
KR20170044204A (ko) * 2014-09-03 2017-04-24 씨4엑스 디스커버리 리미티드 오렉신―１ 수용체의 억제제로서의 치료 화합물

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US8084601B2 (en) 2008-09-11 2011-12-27 Royal Holloway And Bedford New College Royal Holloway, University Of London Oligomers
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