KR20100029861A - 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는 조성물 및 이를 사용하는 방법 - Google Patents
안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는 조성물 및 이를 사용하는 방법 Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33242901P | 2001-11-16 | 2001-11-16 | |
| US60/332,429 | 2001-11-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020047007410A Division KR101012904B1 (ko) | 2001-11-16 | 2002-11-13 | 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20100029861A true KR20100029861A (ko) | 2010-03-17 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020107004734A Ceased KR20100029861A (ko) | 2001-11-16 | 2002-11-13 | 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는 조성물 및 이를 사용하는 방법 |
| KR1020047007410A Expired - Fee Related KR101012904B1 (ko) | 2001-11-16 | 2002-11-13 | 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법 |
Family Applications After (1)
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| KR1020047007410A Expired - Fee Related KR101012904B1 (ko) | 2001-11-16 | 2002-11-13 | 안지오포이에틴-유사 단백질 3 ａｎｇｐｔｌ3을 함유하는조성물 및 이를 사용하는 방법 |
Country Status (14)
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| US (3) | US7267819B2 (enExample) |
| EP (1) | EP1451578B1 (enExample) |
| JP (2) | JP5105696B2 (enExample) |
| KR (2) | KR20100029861A (enExample) |
| CN (2) | CN1615440A (enExample) |
| AU (1) | AU2002348286B2 (enExample) |
| CA (1) | CA2464542C (enExample) |
| ES (1) | ES2429034T3 (enExample) |
| IL (2) | IL161542A0 (enExample) |
| MX (1) | MXPA04004609A (enExample) |
| NO (1) | NO336021B1 (enExample) |
| NZ (1) | NZ532852A (enExample) |
| WO (1) | WO2003044172A2 (enExample) |
| ZA (1) | ZA200403070B (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050123925A1 (en) | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| ES2429034T3 (es) | 2001-11-16 | 2013-11-12 | Genentech, Inc. | Uso de antagonistas de ANGPTL3 para el tratamiento de enfermedades hepáticas |
| JP5349752B2 (ja) * | 2003-08-21 | 2013-11-20 | デュシェネ インク | 微量栄養素サプリメント |
| EP2361931B1 (en) * | 2004-07-20 | 2017-12-06 | Genentech, Inc. | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
| LT1781698T (lt) * | 2004-07-20 | 2016-09-26 | Genentech, Inc. | Į angiopoetiną panašaus baltymo 4 kompozicijos ir panaudojimo būdai |
| US8604185B2 (en) | 2004-07-20 | 2013-12-10 | Genentech, Inc. | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
| US7807645B2 (en) | 2005-09-23 | 2010-10-05 | The Regents Of The University Of California | Method of treating degenerative disorders of the nervous system by administration of fibrinogen fragment |
| HUE033960T2 (en) * | 2006-12-08 | 2018-01-29 | Lexicon Pharmaceuticals Inc | Monoclonal Antibodies to ANGPTL3 |
| EP2265638A1 (en) | 2008-04-14 | 2010-12-29 | Hadasit Medical Research Services And Development Ltd. | Stable cell binding chimeric peptides |
| CN101852805B (zh) * | 2009-03-31 | 2015-04-01 | 浙江大学 | Angptl3作为卵巢癌的诊断标记物的用途 |
| PT2453921E (pt) | 2009-07-14 | 2015-09-25 | Novartis Ag | Diferenciação de células estaminais mesenquimais |
| AU2011203986C1 (en) * | 2010-01-08 | 2015-03-05 | Ionis Pharmaceuticals, Inc. | Modulation of angiopoietin-like 3 expression |
| AU2015200969A1 (en) * | 2010-01-08 | 2015-03-19 | Ionis Pharmaceuticals, Inc. | Modulation of angiopoietin-like 3 expression |
| US9140682B2 (en) * | 2010-02-02 | 2015-09-22 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University | Controlled tunnel gap device for sequencing polymers |
| EP2668499A4 (en) * | 2011-01-29 | 2015-05-27 | Astute Medical Inc | METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE |
| AR087329A1 (es) | 2011-06-17 | 2014-03-19 | Regeneron Pharma | Anticuerpos humanos contra proteina 3 de tipo angiopoietina humana |
| AU2013202137B2 (en) * | 2012-01-24 | 2015-09-10 | Inter-K Pty Limited | Peptide agents for cancer therapy |
| MA38369B1 (fr) | 2013-03-08 | 2018-10-31 | Novartis Ag | Peptides et compositions pour le traitement d'une lesion de l'articulation |
| JO3564B1 (ar) | 2013-03-08 | 2020-07-05 | Novartis Ag | ببتيدات وتركيبات لعلاج ضرر المفاصل |
| CN104062432B (zh) * | 2013-03-22 | 2016-01-20 | 中山大学 | ang2在制备ECTC血管类型肝癌诊断试剂及治疗药物中的应用 |
| IL296543B2 (en) | 2013-05-01 | 2025-02-01 | Ionis Pharmaceuticals Inc | Compositions and methods for modulating HBV and TTR expression |
| AU2014369900B2 (en) | 2013-12-24 | 2021-05-20 | Ionis Pharmaceuticals, Inc. | Modulation of angiopoietin-like 3 expression |
| BR122020024443B1 (pt) | 2014-05-01 | 2022-02-22 | Ionis Pharmaceuticals, Inc | Composto e composição farmacêutica para modulação da expressão de angptl3 |
| CN105021827B (zh) * | 2015-07-17 | 2016-09-28 | 北京大学第一医院 | 检测血清血管生成素样蛋白2含量的物质在制备检测肝脏炎症和纤维化程度产品中的应用 |
| JP7486920B2 (ja) | 2015-11-06 | 2024-05-20 | アイオーニス ファーマシューティカルズ， インコーポレーテッド | アポリポタンパク質（ａ）発現の調節 |
| KR102487839B1 (ko) * | 2016-02-04 | 2023-01-12 | 리제너론 파마슈티칼스 인코포레이티드 | 조작된 angptl8 유전자를 갖는 비인간 동물 |
| MA43734A (fr) | 2016-03-03 | 2018-11-28 | Regeneron Pharma | Procédés de traitement de patients atteints d'hyperlipidémie par administration d'un inhibiteur de pcsk9 en combinaison avec un inhibiteur d'angptl3 |
| KR20250004009A (ko) | 2017-09-14 | 2025-01-07 | 애로우헤드 파마슈티컬스 인코포레이티드 | 안지오포이에틴-유사 3 (ANGPTL3)의 발현을 억제하기 위한 RNAi 작용제 및 조성물, 및 사용 방법 |
| AR116566A1 (es) | 2018-10-03 | 2021-05-19 | Novartis Ag | Administración sostenida de polipéptidos similares a la angiopoyetina 3 |
| WO2020099482A2 (en) * | 2018-11-13 | 2020-05-22 | Lipigon Pharmaceuticals Ab | Angptl 3 oligonucleotides influencing the regulation of the fatty acid metabolism |
| TWI747098B (zh) * | 2018-12-21 | 2021-11-21 | 美商美國禮來大藥廠 | 抗angptl3/8複合物抗體及其使用方法 |
| EP3993820A4 (en) * | 2019-07-04 | 2023-08-16 | Cadila Healthcare Limited | VACCINE BASED ON ANGPTL3 FOR THE TREATMENT OF LIVER DISEASES |
| CN111122872B (zh) * | 2019-11-20 | 2023-01-20 | 中山大学附属第一医院 | 血管生成素样蛋白7在心力衰竭预后评估中的应用 |
| CN110938144B (zh) * | 2019-11-27 | 2022-07-26 | 复旦大学附属儿科医院 | 一种抗angptl3单克隆抗体及其在制备治疗肾病综合征药物中的用途 |
| WO2022187353A1 (en) * | 2021-03-05 | 2022-09-09 | Anji Pharmaceuticals Inc. | Methods and compositions for treating sepsis |
| CN114934021B (zh) * | 2022-04-21 | 2023-08-08 | 复旦大学附属儿科医院 | 一种Angptl3敲除的鼠永生化足细胞系及其应用 |
| CN120254294B (zh) * | 2025-06-05 | 2025-09-09 | 南昌大学第一附属医院 | Angptl3在乙肝相关慢加急性肝衰竭预后中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596850B1 (en) * | 1998-01-30 | 2003-07-22 | Ixsys, Incorporated | Anti-αv3β3 recombinant human antibodies, nucleic acids encoding same |
| EP0917878A4 (en) | 1997-02-26 | 2004-05-19 | Toray Industries | REMEDIES FOR HEPATITIS |
| US5972338A (en) * | 1997-09-19 | 1999-10-26 | Genentech, Inc. | Tie ligands homologues |
| US6030831A (en) * | 1997-09-19 | 2000-02-29 | Genetech, Inc. | Tie ligand homologues |
| WO1999055869A1 (en) * | 1998-04-27 | 1999-11-04 | Zymogenetics, Inc. | Novel polypeptide growth factors and materials and methods for making them |
| CA2332109A1 (en) * | 1998-05-12 | 1999-11-18 | Human Genome Sciences, Inc. | 97 human secreted proteins |
| WO1999067382A2 (en) * | 1998-06-24 | 1999-12-29 | Compugen Ltd. | Angiopoietin-like growth factor sequences |
| JP2003531811A (ja) * | 1999-03-08 | 2003-10-28 | ジェネンテック・インコーポレーテッド | 血管形成及び心臓血管新生の促進又は阻害 |
| ES2429034T3 (es) | 2001-11-16 | 2013-11-12 | Genentech, Inc. | Uso de antagonistas de ANGPTL3 para el tratamiento de enfermedades hepáticas |
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2002
- 2002-11-13 ES ES02782310T patent/ES2429034T3/es not_active Expired - Lifetime
- 2002-11-13 WO PCT/US2002/036865 patent/WO2003044172A2/en not_active Ceased
- 2002-11-13 JP JP2003545797A patent/JP5105696B2/ja not_active Expired - Fee Related
- 2002-11-13 CA CA2464542A patent/CA2464542C/en not_active Expired - Fee Related
- 2002-11-13 EP EP02782310.3A patent/EP1451578B1/en not_active Expired - Lifetime
- 2002-11-13 KR KR1020107004734A patent/KR20100029861A/ko not_active Ceased
- 2002-11-13 IL IL16154202A patent/IL161542A0/xx not_active IP Right Cessation
- 2002-11-13 KR KR1020047007410A patent/KR101012904B1/ko not_active Expired - Fee Related
- 2002-11-13 MX MXPA04004609A patent/MXPA04004609A/es active IP Right Grant
- 2002-11-13 CN CNA028271920A patent/CN1615440A/zh active Pending
- 2002-11-13 AU AU2002348286A patent/AU2002348286B2/en not_active Ceased
- 2002-11-13 NZ NZ532852A patent/NZ532852A/en not_active IP Right Cessation
- 2002-11-13 CN CN2010102426068A patent/CN101905024A/zh active Pending
- 2002-11-15 US US10/298,461 patent/US7267819B2/en not_active Expired - Lifetime
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2004
- 2004-04-22 ZA ZA2004/03070A patent/ZA200403070B/en unknown
- 2004-06-09 NO NO20042410A patent/NO336021B1/no not_active IP Right Cessation
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2006
- 2006-09-29 US US11/537,567 patent/US20070134250A1/en not_active Abandoned
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2008
- 2008-05-28 US US12/128,545 patent/US8541376B2/en not_active Expired - Fee Related
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2009
- 2009-11-13 JP JP2009259497A patent/JP2010100624A/ja active Pending
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- 2010-02-11 IL IL203894A patent/IL203894A/en not_active IP Right Cessation
Also Published As
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| IL161542A0 (en) | 2004-09-27 |
| US20030215451A1 (en) | 2003-11-20 |
| JP2005521643A (ja) | 2005-07-21 |
| US20070134250A1 (en) | 2007-06-14 |
| WO2003044172A3 (en) | 2003-11-20 |
| AU2002348286B2 (en) | 2008-04-03 |
| US20090098117A1 (en) | 2009-04-16 |
| EP1451578A4 (en) | 2006-02-01 |
| NO20042410L (no) | 2004-06-09 |
| US8541376B2 (en) | 2013-09-24 |
| NO336021B1 (no) | 2015-04-20 |
| ZA200403070B (en) | 2005-06-29 |
| CA2464542C (en) | 2015-01-20 |
| IL203894A (en) | 2013-09-30 |
| JP2010100624A (ja) | 2010-05-06 |
| CA2464542A1 (en) | 2003-05-30 |
| US7267819B2 (en) | 2007-09-11 |
| CN1615440A (zh) | 2005-05-11 |
| ES2429034T3 (es) | 2013-11-12 |
| KR20050044485A (ko) | 2005-05-12 |
| EP1451578B1 (en) | 2013-08-21 |
| CN101905024A (zh) | 2010-12-08 |
| NZ532852A (en) | 2006-08-31 |
| EP1451578A2 (en) | 2004-09-01 |
| MXPA04004609A (es) | 2004-08-12 |
| WO2003044172B1 (en) | 2004-03-18 |
| KR101012904B1 (ko) | 2011-02-08 |
| WO2003044172A2 (en) | 2003-05-30 |
| AU2002348286A1 (en) | 2003-06-10 |
| JP5105696B2 (ja) | 2012-12-26 |
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