KR20100017565A - (ｒ)-2-메틸피롤리딘 및 (ｓ)-2-메틸피롤리딘 및 이의 타르트레이트 염의 제조 방법 - Google Patents
(ｒ)-2-메틸피롤리딘 및 (ｓ)-2-메틸피롤리딘 및 이의 타르트레이트 염의 제조 방법 Download PDFInfo
- Publication number
- KR20100017565A KR20100017565A KR1020097025141A KR20097025141A KR20100017565A KR 20100017565 A KR20100017565 A KR 20100017565A KR 1020097025141 A KR1020097025141 A KR 1020097025141A KR 20097025141 A KR20097025141 A KR 20097025141A KR 20100017565 A KR20100017565 A KR 20100017565A
- Authority
- KR
- South Korea
- Prior art keywords
- methylpyrrolidine
- methyl
- tartrate
- phenyl
- pyrrolidin
- Prior art date
Links
- 0 COC(c1ccc(cc(cc2)O*)c2c1)=O Chemical compound COC(c1ccc(cc(cc2)O*)c2c1)=O 0.000 description 12
- QHAUJIBFWOFOEN-UHFFFAOYSA-N CC(C)(CCOc1cccc(C=O)c1)CC(C)(C)O Chemical compound CC(C)(CCOc1cccc(C=O)c1)CC(C)(C)O QHAUJIBFWOFOEN-UHFFFAOYSA-N 0.000 description 1
- YFOROZRYRDYVGD-UHFFFAOYSA-O CCCCNCC[OH+]C(C=C1)C=C1N(CN(C1)C(C(C(CC2)F)=CC2F)=O)C1O Chemical compound CCCCNCC[OH+]C(C=C1)C=C1N(CN(C1)C(C(C(CC2)F)=CC2F)=O)C1O YFOROZRYRDYVGD-UHFFFAOYSA-O 0.000 description 1
- UKZOPQRTQJERQC-UHFFFAOYSA-N COC(c1ccc(cc(cc2)O)c2c1)=O Chemical compound COC(c1ccc(cc(cc2)O)c2c1)=O UKZOPQRTQJERQC-UHFFFAOYSA-N 0.000 description 1
- QNXSIUBBGPHDDE-UHFFFAOYSA-N O=C1c2ccccc2CC1 Chemical compound O=C1c2ccccc2CC1 QNXSIUBBGPHDDE-UHFFFAOYSA-N 0.000 description 1
- KAUQJMHLAFIZDU-UHFFFAOYSA-N OC(c1ccc(cc(cc2)O)c2c1)=O Chemical compound OC(c1ccc(cc(cc2)O)c2c1)=O KAUQJMHLAFIZDU-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US92735607P | 2007-05-03 | 2007-05-03 | |
| US60/927,356 | 2007-05-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20100017565A true KR20100017565A (ko) | 2010-02-16 |
Family
ID=39688886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097025141A KR20100017565A (ko) | 2007-05-03 | 2008-05-02 | (ｒ)-2-메틸피롤리딘 및 (ｓ)-2-메틸피롤리딘 및 이의 타르트레이트 염의 제조 방법 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP2152669A1 (pt) |
| JP (1) | JP5698887B2 (pt) |
| KR (1) | KR20100017565A (pt) |
| CN (1) | CN101679237A (pt) |
| AU (1) | AU2008248168B2 (pt) |
| BR (1) | BRPI0810330A2 (pt) |
| CA (1) | CA2686033A1 (pt) |
| EA (1) | EA019031B1 (pt) |
| IL (1) | IL201627A (pt) |
| MX (1) | MX2009011787A (pt) |
| NZ (1) | NZ580948A (pt) |
| UA (1) | UA99913C2 (pt) |
| WO (1) | WO2008137087A1 (pt) |
| ZA (1) | ZA200907643B (pt) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2397283T3 (es) | 2006-07-25 | 2013-03-06 | Cephalon, Inc. | Derivados de piridizinona |
| US8383657B2 (en) | 2007-12-21 | 2013-02-26 | Abbott Laboratories | Thiazolylidine urea and amide derivatives and methods of use thereof |
| EP2752406A1 (en) * | 2008-01-30 | 2014-07-09 | Cephalon, Inc. | Substituted pyridazine derivatives which have histamine H3 antagonist activity |
| EP3237408B1 (en) * | 2014-12-23 | 2018-10-31 | Cephalon, Inc. | Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3329974A1 (de) | 1983-08-19 | 1985-02-28 | Bayer Ag, 5090 Leverkusen | Herstellung von hydrierten nitrilkautschuken |
| DE3433392A1 (de) | 1984-09-12 | 1986-03-20 | Bayer Ag, 5090 Leverkusen | Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer |
| FR2714849B1 (fr) | 1994-01-13 | 1996-04-05 | Inst Francais Du Petrole | Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique. |
| DE4403479A1 (de) | 1994-02-04 | 1995-08-10 | Basf Ag | Verfahren zur Herstellung von Hydroxylammoniumsalzen |
| WO2004024707A2 (en) * | 2002-09-16 | 2004-03-25 | Abbott Laboratories | Process for preparing amine type substituted benzofurans |
| US7153889B2 (en) | 2002-11-12 | 2006-12-26 | Abbott Laboratories | Bicyclic-substituted amines as histamine-3 receptor ligands |
| CN100543050C (zh) | 2004-03-08 | 2009-09-23 | 独立行政法人科学技术振兴机构 | 高分子担载金属簇组合物 |
| US7145005B2 (en) | 2004-05-12 | 2006-12-05 | Abbott Laboratories | 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation |
| ES2299074T3 (es) | 2004-06-02 | 2008-05-16 | F. Hoffmann-La Roche Ag | Derivados de naftaleno utiles como ligandos del receptor 3 de la histamina. |
| WO2006059778A1 (ja) | 2004-12-01 | 2006-06-08 | Banyu Pharmaceutical Co., Ltd. | 置換ピリドン誘導体 |
| JP2008524252A (ja) | 2004-12-17 | 2008-07-10 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｃｎｓ障害の処置のためのテトラヒドロイソキノリン化合物 |
| JP2008526895A (ja) | 2005-01-21 | 2008-07-24 | シェーリング コーポレイション | ヒスタミンｈ３アンタゴニストとして有用なイミダゾールおよびベンゾイミダゾール誘導体 |
| CA2602336A1 (en) | 2005-03-31 | 2006-10-05 | Ucb Pharma S.A. | Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses |
| GB0514812D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| CA2627234A1 (en) | 2005-10-27 | 2007-05-03 | Ucb Pharma, S.A. | Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses |
| WO2007094962A2 (en) | 2006-02-09 | 2007-08-23 | Athersys, Inc. | Pyrazoles for the treatment of obesity and other cns disorders |
| WO2007099423A1 (en) | 2006-03-02 | 2007-09-07 | Pfizer Products Inc. | 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists |
| US20090163482A1 (en) | 2006-03-13 | 2009-06-25 | Mchardy Stanton Furst | Tetralines antagonists of the h-3 receptor |
| WO2008005338A1 (en) | 2006-06-29 | 2008-01-10 | Arena Pharmaceuticals, Inc. | Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto |
| ES2397283T3 (es) * | 2006-07-25 | 2013-03-06 | Cephalon, Inc. | Derivados de piridizinona |
-
2008
- 2008-05-02 AU AU2008248168A patent/AU2008248168B2/en not_active Ceased
- 2008-05-02 EA EA200971019A patent/EA019031B1/ru not_active IP Right Cessation
- 2008-05-02 CN CN200880021225A patent/CN101679237A/zh active Pending
- 2008-05-02 MX MX2009011787A patent/MX2009011787A/es active IP Right Grant
- 2008-05-02 WO PCT/US2008/005702 patent/WO2008137087A1/en active Application Filing
- 2008-05-02 CA CA002686033A patent/CA2686033A1/en not_active Abandoned
- 2008-05-02 UA UAA200912476A patent/UA99913C2/ru unknown
- 2008-05-02 EP EP08754205A patent/EP2152669A1/en not_active Withdrawn
- 2008-05-02 KR KR1020097025141A patent/KR20100017565A/ko not_active Application Discontinuation
- 2008-05-02 NZ NZ580948A patent/NZ580948A/en not_active IP Right Cessation
- 2008-05-02 BR BRPI0810330-5A2A patent/BRPI0810330A2/pt not_active IP Right Cessation
- 2008-05-02 JP JP2010507416A patent/JP5698887B2/ja not_active Expired - Fee Related
-
2009
- 2009-10-19 IL IL201627A patent/IL201627A/en not_active IP Right Cessation
- 2009-10-30 ZA ZA2009/07643A patent/ZA200907643B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008137087A1 (en) | 2008-11-13 |
| JP5698887B2 (ja) | 2015-04-08 |
| IL201627A0 (en) | 2010-05-31 |
| CN101679237A (zh) | 2010-03-24 |
| JP2010526142A (ja) | 2010-07-29 |
| AU2008248168A1 (en) | 2008-11-13 |
| AU2008248168B2 (en) | 2013-03-21 |
| BRPI0810330A2 (pt) | 2014-10-14 |
| NZ580948A (en) | 2011-04-29 |
| EA019031B1 (ru) | 2013-12-30 |
| ZA200907643B (en) | 2014-03-26 |
| EA200971019A1 (ru) | 2010-04-30 |
| CA2686033A1 (en) | 2008-11-13 |
| UA99913C2 (ru) | 2012-10-25 |
| IL201627A (en) | 2014-06-30 |
| EP2152669A1 (en) | 2010-02-17 |
| MX2009011787A (es) | 2009-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application |