MX2009011787A - Procesos para preparar (r)-2-metilpirrolidina y (s)-2-metilpirrolidina y sales de tartrato de las mismas. - Google Patents

Procesos para preparar (r)-2-metilpirrolidina y (s)-2-metilpirrolidina y sales de tartrato de las mismas.

Info

Publication number
MX2009011787A
MX2009011787A MX2009011787A MX2009011787A MX2009011787A MX 2009011787 A MX2009011787 A MX 2009011787A MX 2009011787 A MX2009011787 A MX 2009011787A MX 2009011787 A MX2009011787 A MX 2009011787A MX 2009011787 A MX2009011787 A MX 2009011787A
Authority
MX
Mexico
Prior art keywords
methylpyrrolidine
preparing
processes
tartrate salts
tartrate
Prior art date
Application number
MX2009011787A
Other languages
English (en)
Inventor
Christie Michael
J Petraitis Joseph
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of MX2009011787A publication Critical patent/MX2009011787A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención proporciona un proceso corto, seguro, económico, comercialmente escalable, para preparar (R) o (S) 2-metilpirrolidina a partir de 2-metilpirrolina, que no requiere el aislamiento de intermediarios sintéticos.
MX2009011787A 2007-05-03 2008-05-02 Procesos para preparar (r)-2-metilpirrolidina y (s)-2-metilpirrolidina y sales de tartrato de las mismas. MX2009011787A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03
PCT/US2008/005702 WO2008137087A1 (en) 2007-05-03 2008-05-02 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Publications (1)

Publication Number Publication Date
MX2009011787A true MX2009011787A (es) 2009-11-13

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011787A MX2009011787A (es) 2007-05-03 2008-05-02 Procesos para preparar (r)-2-metilpirrolidina y (s)-2-metilpirrolidina y sales de tartrato de las mismas.

Country Status (14)

Country Link
EP (1) EP2152669A1 (es)
JP (1) JP5698887B2 (es)
KR (1) KR20100017565A (es)
CN (1) CN101679237A (es)
AU (1) AU2008248168B2 (es)
BR (1) BRPI0810330A2 (es)
CA (1) CA2686033A1 (es)
EA (1) EA019031B1 (es)
IL (1) IL201627A (es)
MX (1) MX2009011787A (es)
NZ (1) NZ580948A (es)
UA (1) UA99913C2 (es)
WO (1) WO2008137087A1 (es)
ZA (1) ZA200907643B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2397283T3 (es) 2006-07-25 2013-03-06 Cephalon, Inc. Derivados de piridizinona
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
EP2752406A1 (en) * 2008-01-30 2014-07-09 Cephalon, Inc. Substituted pyridazine derivatives which have histamine H3 antagonist activity
EP3237408B1 (en) * 2014-12-23 2018-10-31 Cephalon, Inc. Methods for preparing fused bicyclic 2, 4-diaminopyrimidine derivatives

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (de) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen Herstellung von hydrierten nitrilkautschuken
DE3433392A1 (de) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer
FR2714849B1 (fr) 1994-01-13 1996-04-05 Inst Francais Du Petrole Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique.
DE4403479A1 (de) 1994-02-04 1995-08-10 Basf Ag Verfahren zur Herstellung von Hydroxylammoniumsalzen
WO2004024707A2 (en) * 2002-09-16 2004-03-25 Abbott Laboratories Process for preparing amine type substituted benzofurans
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
CN100543050C (zh) 2004-03-08 2009-09-23 独立行政法人科学技术振兴机构 高分子担载金属簇组合物
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
ES2299074T3 (es) 2004-06-02 2008-05-16 F. Hoffmann-La Roche Ag Derivados de naftaleno utiles como ligandos del receptor 3 de la histamina.
WO2006059778A1 (ja) 2004-12-01 2006-06-08 Banyu Pharmaceutical Co., Ltd. 置換ピリドン誘導体
JP2008524252A (ja) 2004-12-17 2008-07-10 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｃｎｓ障害の処置のためのテトラヒドロイソキノリン化合物
JP2008526895A (ja) 2005-01-21 2008-07-24 シェーリング コーポレイション ヒスタミンｈ３アンタゴニストとして有用なイミダゾールおよびベンゾイミダゾール誘導体
CA2602336A1 (en) 2005-03-31 2006-10-05 Ucb Pharma S.A. Compounds comprising an oxazole or thiazole moiety, processes for making them, and their uses
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
CA2627234A1 (en) 2005-10-27 2007-05-03 Ucb Pharma, S.A. Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
WO2007094962A2 (en) 2006-02-09 2007-08-23 Athersys, Inc. Pyrazoles for the treatment of obesity and other cns disorders
WO2007099423A1 (en) 2006-03-02 2007-09-07 Pfizer Products Inc. 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists
US20090163482A1 (en) 2006-03-13 2009-06-25 Mchardy Stanton Furst Tetralines antagonists of the h-3 receptor
WO2008005338A1 (en) 2006-06-29 2008-01-10 Arena Pharmaceuticals, Inc. Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto
ES2397283T3 (es) * 2006-07-25 2013-03-06 Cephalon, Inc. Derivados de piridizinona

Also Published As

Publication number Publication date
WO2008137087A1 (en) 2008-11-13
JP5698887B2 (ja) 2015-04-08
IL201627A0 (en) 2010-05-31
CN101679237A (zh) 2010-03-24
JP2010526142A (ja) 2010-07-29
AU2008248168A1 (en) 2008-11-13
AU2008248168B2 (en) 2013-03-21
BRPI0810330A2 (pt) 2014-10-14
NZ580948A (en) 2011-04-29
EA019031B1 (ru) 2013-12-30
ZA200907643B (en) 2014-03-26
EA200971019A1 (ru) 2010-04-30
CA2686033A1 (en) 2008-11-13
UA99913C2 (ru) 2012-10-25
IL201627A (en) 2014-06-30
KR20100017565A (ko) 2010-02-16
EP2152669A1 (en) 2010-02-17

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