KR20090117924A - 거대고리 다형체, 이런 다형체 포함하는 조성물, 및 이의 사용 및 제조방법 - Google Patents

거대고리 다형체, 이런 다형체 포함하는 조성물, 및 이의 사용 및 제조방법 Download PDF

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Publication number
KR20090117924A
KR20090117924A KR1020097017476A KR20097017476A KR20090117924A KR 20090117924 A KR20090117924 A KR 20090117924A KR 1020097017476 A KR1020097017476 A KR 1020097017476A KR 20097017476 A KR20097017476 A KR 20097017476A KR 20090117924 A KR20090117924 A KR 20090117924A
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KR
South Korea
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compound
formula
polymorph
present
tiacumicin
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Ceased
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KR1020097017476A
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English (en)
Korean (ko)
Inventor
유 훙 치우
테시 메리 체
알렉스 로메로
요시 이치카와
유 콩 슈
Original Assignee
옵티머 파마슈티칼즈, 인코포레이티드
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38661942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20090117924(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 옵티머 파마슈티칼즈, 인코포레이티드 filed Critical 옵티머 파마슈티칼즈, 인코포레이티드
Publication of KR20090117924A publication Critical patent/KR20090117924A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
KR1020097017476A 2007-01-22 2008-01-22 거대고리 다형체, 이런 다형체 포함하는 조성물, 및 이의 사용 및 제조방법 Ceased KR20090117924A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US88195007P 2007-01-22 2007-01-22
US60/881,950 2007-01-22
US11/831,886 US7378508B2 (en) 2007-01-22 2007-07-31 Polymorphic crystalline forms of tiacumicin B
US11/831,886 2007-07-31

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020147036325A Division KR20150006082A (ko) 2007-01-22 2008-01-22 거대고리 다형체, 이런 다형체를 포함하는 조성물, 및 이의 사용 및 제조방법

Publications (1)

Publication Number Publication Date
KR20090117924A true KR20090117924A (ko) 2009-11-16

Family

ID=38661942

Family Applications (2)

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KR1020097017476A Ceased KR20090117924A (ko) 2007-01-22 2008-01-22 거대고리 다형체, 이런 다형체 포함하는 조성물, 및 이의 사용 및 제조방법
KR1020147036325A Ceased KR20150006082A (ko) 2007-01-22 2008-01-22 거대고리 다형체, 이런 다형체를 포함하는 조성물, 및 이의 사용 및 제조방법

Family Applications After (1)

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KR1020147036325A Ceased KR20150006082A (ko) 2007-01-22 2008-01-22 거대고리 다형체, 이런 다형체를 포함하는 조성물, 및 이의 사용 및 제조방법

Country Status (23)

Country Link
US (5) US7378508B2 (https=)
EP (3) EP3412678B1 (https=)
JP (2) JP5468388B2 (https=)
KR (2) KR20090117924A (https=)
CN (2) CN102746353A (https=)
BR (1) BRPI0806878A2 (https=)
CA (2) CA2676061C (https=)
CY (1) CY1120358T1 (https=)
DK (1) DK2125850T3 (https=)
ES (2) ES2676308T3 (https=)
HR (1) HRP20180912T1 (https=)
HU (2) HUE039395T2 (https=)
IL (2) IL199984A0 (https=)
LT (1) LT2125850T (https=)
MX (2) MX2009007730A (https=)
NZ (2) NZ578697A (https=)
PL (2) PL2125850T3 (https=)
PT (2) PT2125850T (https=)
RU (1) RU2478643C2 (https=)
SI (1) SI2125850T1 (https=)
TR (1) TR201810589T4 (https=)
TW (2) TWI425942B (https=)
WO (1) WO2008091554A1 (https=)

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US7906489B2 (en) 2004-05-14 2011-03-15 Optimer Pharmaceuticals, Inc. 18-membered macrocycles and analogs thereof
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US7935377B2 (en) * 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
US7378508B2 (en) * 2007-01-22 2008-05-27 Optimer Pharmaceuticals, Inc. Polymorphic crystalline forms of tiacumicin B
MX2010000465A (es) * 2007-07-12 2010-08-30 Tragara Pharmaceuticals Inc Metodos y composiciones para el tratamiento de cancer, tumores y alteraciones relacionadas con tumores.
TWI523654B (zh) 2007-11-27 2016-03-01 默沙東藥廠 抗生素巨環化合物以及其製造及使用之方法
EA027622B1 (ru) * 2010-02-05 2017-08-31 ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" Твердофазные формы макроциклических ингибиторов киназы
MX2012013372A (es) * 2010-05-18 2013-05-01 Optimer Pharmaceuticals Inc Metodos para tratar infecciones bacterianas recurrentes.
US20140024609A1 (en) * 2011-02-04 2014-01-23 Optimer Pharmaceuticals ,Inc. Treatment of Bacterial Infections
WO2013138748A1 (en) * 2012-03-16 2013-09-19 Optimer Pharmaceuticals, Inc. Prevention of clostridium difficile infection in high risk patients
US8722863B2 (en) * 2012-05-10 2014-05-13 Teva Pharmaceutical Works Ltd. Solid state forms of fidaxomycin and processes for preparation thereof
WO2013170142A1 (en) 2012-05-10 2013-11-14 Teva Pharmaceutical Works Ltd. Solid state forms of fidaxomycin and processes for preparation thereof
JO3464B1 (ar) * 2013-01-15 2020-07-05 Astellas Pharma Europe Ltd التركيبات الخاصة بمركبات التياكوميسين
CN105142612A (zh) 2013-03-08 2015-12-09 奇普拉股份有限公司 用于直肠给药的药物组合物
CN103275152B (zh) * 2013-05-29 2015-11-18 华北制药集团新药研究开发有限责任公司 一种高纯度非达霉素的制备方法
CN103275153B (zh) * 2013-06-27 2016-03-23 华北制药集团新药研究开发有限责任公司 一种非达霉素晶体的制备方法
CN104560766B (zh) * 2013-10-16 2017-07-28 浙江海正药业股份有限公司 一种游动放线菌菌株及其应用
US20150141356A1 (en) * 2013-11-15 2015-05-21 Optimer Pharmaceuticals, Inc. Treatment of Clostridium Difficile Infection in High Risk Patients
WO2015127955A1 (en) 2014-02-25 2015-09-03 Olon S.P.A. A new polymorph of tiacumicin b and process for preparation thereof
CA2940433A1 (en) 2014-02-25 2015-09-03 Olon S.P.A. Process for preparing novel forms of tiacumicin b
CA2940902C (en) * 2014-03-18 2022-10-25 Xellia Pharmaceuticals Aps Polymorphs and solid states of tiacumicin b
CA2948400A1 (en) 2014-05-09 2015-11-12 Astellas Pharma Europe Ltd Treatment regimen tiacumicin compound
WO2015175695A1 (en) * 2014-05-13 2015-11-19 Debrabander Jef Small molecule compounds selective against gram-negative bacterial infections
CN104098637B (zh) 2014-07-09 2017-01-04 浙江海正药业股份有限公司 一种纯化非达霉素的方法
MA41689A (fr) * 2014-10-15 2017-08-22 Bioxcel Corp Prévention ou traitement de troubles du sommeil au moyen d'une formulation de dexmédétomidine
EA034885B1 (ru) 2015-07-03 2020-04-02 Астеллас Фарма Юэроп Лтд. Новая схема лечения тиакумициновым соединением
CN112190589A (zh) * 2020-11-17 2021-01-08 首都医科大学附属北京胸科医院 非达霉素在制备抑制鸟分枝杆菌活性的产品中的应用

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Publication number Publication date
US20130252914A1 (en) 2013-09-26
CA2880860A1 (en) 2008-07-31
BRPI0806878A2 (pt) 2014-06-24
JP2010516681A (ja) 2010-05-20
LT2125850T (lt) 2018-08-10
PT3412678T (pt) 2020-09-29
CN101663312B (zh) 2013-10-23
EP2125850B1 (en) 2018-05-30
SI2125850T1 (en) 2018-08-31
US7863249B2 (en) 2011-01-04
NZ601347A (en) 2013-11-29
US20090163428A1 (en) 2009-06-25
US20070259949A1 (en) 2007-11-08
PL3412678T3 (pl) 2020-12-14
PT2125850T (pt) 2018-07-11
CN101663312A (zh) 2010-03-03
WO2008091554A1 (en) 2008-07-31
KR20150006082A (ko) 2015-01-15
MX348083B (es) 2017-05-25
PL2125850T3 (pl) 2018-08-31
RU2478643C2 (ru) 2013-04-10
MX2009007730A (es) 2009-08-07
CY1120358T1 (el) 2019-07-10
JP5468388B2 (ja) 2014-04-09
HUE039395T2 (hu) 2018-12-28
CA2676061A1 (en) 2008-07-31
EP3412678A1 (en) 2018-12-12
US8859510B2 (en) 2014-10-14
RU2009131727A (ru) 2011-02-27
JP5764168B2 (ja) 2015-08-12
US7378508B2 (en) 2008-05-27
EP3412678B1 (en) 2020-08-19
TW200840562A (en) 2008-10-16
NZ578697A (en) 2012-08-31
TW201350114A (zh) 2013-12-16
CN102746353A (zh) 2012-10-24
EP2468761A1 (en) 2012-06-27
US20100081800A1 (en) 2010-04-01
HUE052444T2 (hu) 2021-05-28
JP2013241440A (ja) 2013-12-05
CA2676061C (en) 2016-01-19
ES2676308T3 (es) 2018-07-18
US8883986B2 (en) 2014-11-11
IL220255A0 (en) 2012-07-31
ES2821384T3 (es) 2021-04-26
DK2125850T3 (en) 2018-07-30
AU2008209580A1 (en) 2008-07-31
TWI425942B (zh) 2014-02-11
TWI453015B (zh) 2014-09-21
EP2125850A1 (en) 2009-12-02
HRP20180912T1 (hr) 2018-07-27
US20080194497A1 (en) 2008-08-14
IL199984A0 (en) 2010-04-15
TR201810589T4 (tr) 2018-08-27

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