KR20090098880A - 트랜스페린 융합 단백질 라이브러리 - Google Patents

트랜스페린 융합 단백질 라이브러리 Download PDF

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Publication number
KR20090098880A
KR20090098880A KR1020097014465A KR20097014465A KR20090098880A KR 20090098880 A KR20090098880 A KR 20090098880A KR 1020097014465 A KR1020097014465 A KR 1020097014465A KR 20097014465 A KR20097014465 A KR 20097014465A KR 20090098880 A KR20090098880 A KR 20090098880A
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KR
South Korea
Prior art keywords
fusion protein
amino acid
protein
moiety
sequence
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Ceased
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KR1020097014465A
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English (en)
Korean (ko)
Inventor
앤드류 존 터너
베이양 왕
Original Assignee
바이오렉시스 파마슈티칼 코포레이션
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Publication of KR20090098880A publication Critical patent/KR20090098880A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035—Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
KR1020097014465A 2006-12-12 2007-12-07 트랜스페린 융합 단백질 라이브러리 Ceased KR20090098880A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93495106P 2006-12-12 2006-12-12
US60/934,951 2006-12-12

Publications (1)

Publication Number Publication Date
KR20090098880A true KR20090098880A (ko) 2009-09-17

Family

ID=39362844

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097014465A Ceased KR20090098880A (ko) 2006-12-12 2007-12-07 트랜스페린 융합 단백질 라이브러리

Country Status (13)

Country Link
US (1) US8822639B2 (https=)
EP (2) EP2114999A2 (https=)
JP (1) JP5492563B2 (https=)
KR (1) KR20090098880A (https=)
CN (1) CN101622274A (https=)
AU (1) AU2007331195A1 (https=)
CA (1) CA2673085C (https=)
ES (1) ES2535358T3 (https=)
IL (1) IL198815A0 (https=)
MX (1) MX2009006398A (https=)
NO (1) NO20092591L (https=)
WO (1) WO2008072075A2 (https=)
ZA (1) ZA200904757B (https=)

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US8401798B2 (en) * 2008-06-06 2013-03-19 Dna Twopointo, Inc. Systems and methods for constructing frequency lookup tables for expression systems
AU2010306940A1 (en) 2009-10-12 2012-06-07 Smith, Larry Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro
CN102258767B (zh) * 2010-05-24 2013-05-15 黄敏铨 促进伤口愈合的组合物
WO2012057934A1 (en) * 2010-10-26 2012-05-03 The Rockefeller University Immunogenic agents
AU2012211519B2 (en) * 2011-02-02 2015-07-30 Medipost Co., Ltd. Use of ICAM-1 for prevention or treatment of neurological diseases
US9623117B2 (en) * 2011-04-04 2017-04-18 Wisconsin Alumni Research Foundation Method for selective targeting and entry of bacterial toxins to cells
US9156897B2 (en) * 2012-06-08 2015-10-13 Alkermes, Inc. Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
EP2929351B1 (en) * 2012-12-10 2019-10-09 The University of Queensland Cell-free biofragment compositions and related systems, devices, and methods
JP7235436B2 (ja) * 2014-11-10 2023-03-08 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 細胞の表面上にポリペプチドを発現させるための組成物および方法
WO2017170418A1 (ja) * 2016-03-30 2017-10-05 株式会社カネカ エンドヌクレアーゼ活性を有するポリペプチド及びその製造方法
SG11201901495YA (en) * 2016-08-25 2019-03-28 Jcr Pharmaceuticals Co Ltd Method for producing antibody fusion protein
JP7627910B2 (ja) * 2018-12-21 2025-02-07 フエー・イー・ベー・フエー・ゼツト・ウエー サイトカイン及び足場タンパク質を含む融合タンパク質
CN113045670B (zh) * 2019-12-27 2022-11-01 华南农业大学 一种可溶性鸡α干扰素融合蛋白及其生产方法与应用
MX2023011268A (es) 2021-03-24 2023-12-14 Alkermes Inc Anticuerpos upar y proteínas de fusión con estos.
US20250041398A1 (en) * 2021-12-16 2025-02-06 Thomas Jefferson University A therapeutic against crimean-congo hemorrhagic fever virus

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Also Published As

Publication number Publication date
CN101622274A (zh) 2010-01-06
CA2673085A1 (en) 2008-06-19
EP2479189B1 (en) 2015-02-25
JP5492563B2 (ja) 2014-05-14
JP2010512160A (ja) 2010-04-22
ES2535358T3 (es) 2015-05-08
WO2008072075A3 (en) 2008-11-06
ZA200904757B (en) 2010-04-28
AU2007331195A1 (en) 2008-06-19
MX2009006398A (es) 2009-06-23
US8822639B2 (en) 2014-09-02
CA2673085C (en) 2013-10-15
NO20092591L (no) 2009-09-11
EP2114999A2 (en) 2009-11-11
IL198815A0 (en) 2011-08-01
EP2479189A1 (en) 2012-07-25
WO2008072075A2 (en) 2008-06-19
US20110086768A1 (en) 2011-04-14

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