KR20090018210A - 통증, 알쯔하이머병 및 정신분열증의 치료에 효과적인 무스카린성 수용체 효능제 - Google Patents
통증, 알쯔하이머병 및 정신분열증의 치료에 효과적인 무스카린성 수용체 효능제 Download PDFInfo
- Publication number
- KR20090018210A KR20090018210A KR1020097000417A KR20097000417A KR20090018210A KR 20090018210 A KR20090018210 A KR 20090018210A KR 1020097000417 A KR1020097000417 A KR 1020097000417A KR 20097000417 A KR20097000417 A KR 20097000417A KR 20090018210 A KR20090018210 A KR 20090018210A
- Authority
- KR
- South Korea
- Prior art keywords
- alkyl
- alkoxy
- cycloalkyl
- piperidyl
- heterocycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 0 C*N(C(CP)C(*)C*NC)C(CC(*(C1N)=C)N)C1N Chemical compound C*N(C(CP)C(*)C*NC)C(CC(*(C1N)=C)N)C1N 0.000 description 10
- SYEUJJXEBCKTQN-IRXDYDNUSA-N CC(C)N([C@@H](CCCC1)[C@H]1N1C(CC2)CCN2C(OC(C)(C)C)=O)C1=O Chemical compound CC(C)N([C@@H](CCCC1)[C@H]1N1C(CC2)CCN2C(OC(C)(C)C)=O)C1=O SYEUJJXEBCKTQN-IRXDYDNUSA-N 0.000 description 2
- LCSLESKXUFZLJI-KBPBESRZSA-N CC(C)(C)OC(N(CC1)CCC1N([C@@H](CCCC1)[C@H]1N1)C1=O)=O Chemical compound CC(C)(C)OC(N(CC1)CCC1N([C@@H](CCCC1)[C@H]1N1)C1=O)=O LCSLESKXUFZLJI-KBPBESRZSA-N 0.000 description 1
- JIWRDSBGQUQMBJ-NFJWQWPMSA-N CC(C)(C)OC(NC1[C@@H](COS(C)(=O)=O)CCCC1)=O Chemical compound CC(C)(C)OC(NC1[C@@H](COS(C)(=O)=O)CCCC1)=O JIWRDSBGQUQMBJ-NFJWQWPMSA-N 0.000 description 1
- IAGJRMOGWXHLOX-JHJMLUEUSA-N CC(C)(C)OC(NCC1[C@@H](CC#N)CCCC1)=O Chemical compound CC(C)(C)OC(NCC1[C@@H](CC#N)CCCC1)=O IAGJRMOGWXHLOX-JHJMLUEUSA-N 0.000 description 1
- YZRONMMFSPJKTL-LSLKUGRBSA-N CC(C)N([C@@H](CCCC1)C1N1C2CCNCC2)C1=O Chemical compound CC(C)N([C@@H](CCCC1)C1N1C2CCNCC2)C1=O YZRONMMFSPJKTL-LSLKUGRBSA-N 0.000 description 1
- PYJAXKIMFNHYSK-MRTLOADZSA-N CC(C)OC(N(CC1)CCC1N(CC1)CCC1N(C(CCCC1)[C@@H]1N1)C1=O)=O Chemical compound CC(C)OC(N(CC1)CCC1N(CC1)CCC1N(C(CCCC1)[C@@H]1N1)C1=O)=O PYJAXKIMFNHYSK-MRTLOADZSA-N 0.000 description 1
- QJJIPMCHISDFDS-MNOVXSKESA-N CC(C)OC(N[C@@H]1[C@@H](CC#N)CCCC1)=O Chemical compound CC(C)OC(N[C@@H]1[C@@H](CC#N)CCCC1)=O QJJIPMCHISDFDS-MNOVXSKESA-N 0.000 description 1
- HXDAXBTXTSITEW-AVVWSFFYSA-N CC(CCCC1)[C@@H]1N(C(CC1)CCN1C1CNCC1)C(N)=O Chemical compound CC(CCCC1)[C@@H]1N(C(CC1)CCN1C1CNCC1)C(N)=O HXDAXBTXTSITEW-AVVWSFFYSA-N 0.000 description 1
- ICXSOTKPIRKVLF-BHSFOZSMSA-N CCCC(CC(CC1)CCC1N([C@H](CCCC1)C1N1)C1=O)C/C=C(/C)\C(OCC)=O Chemical compound CCCC(CC(CC1)CCC1N([C@H](CCCC1)C1N1)C1=O)C/C=C(/C)\C(OCC)=O ICXSOTKPIRKVLF-BHSFOZSMSA-N 0.000 description 1
- JYFFARMJOKOKGD-UHFFFAOYSA-N CCCC(CCN)N(CC1)CCC1N(C(CCCC1)C1N1)C1=O Chemical compound CCCC(CCN)N(CC1)CCC1N(C(CCCC1)C1N1)C1=O JYFFARMJOKOKGD-UHFFFAOYSA-N 0.000 description 1
- NBQMWPNJRXPCPY-DAWZGUTISA-N CCOC(CN(CC1)CC1N(CC1)CCC1N([C@H](CCCC1)C1N1)C1=O)=O Chemical compound CCOC(CN(CC1)CC1N(CC1)CCC1N([C@H](CCCC1)C1N1)C1=O)=O NBQMWPNJRXPCPY-DAWZGUTISA-N 0.000 description 1
- CNPPMLHQUZNOFF-YKSBVNFPSA-N Cc1ccccc1C(N(CC1)CCC1N(CC1)CCC1N([C@@H]1[C@@H](C2)CCCC1)C2=O)=O Chemical compound Cc1ccccc1C(N(CC1)CCC1N(CC1)CCC1N([C@@H]1[C@@H](C2)CCCC1)C2=O)=O CNPPMLHQUZNOFF-YKSBVNFPSA-N 0.000 description 1
- SSJXIUAHEKJCMH-UHFFFAOYSA-N NC(CCCC1)C1N Chemical compound NC(CCCC1)C1N SSJXIUAHEKJCMH-UHFFFAOYSA-N 0.000 description 1
- ZYZCHUMYNSXZQK-SFYZADRCSA-N N[C@@H]1[C@@H](CC#N)CCCC1 Chemical compound N[C@@H]1[C@@H](CC#N)CCCC1 ZYZCHUMYNSXZQK-SFYZADRCSA-N 0.000 description 1
- FAINZCLECVKPCD-QWRGUYRKSA-N O=C(N[C@@H]1[C@@H]2CCCC1)N2C1CCNCC1 Chemical compound O=C(N[C@@H]1[C@@H]2CCCC1)N2C1CCNCC1 FAINZCLECVKPCD-QWRGUYRKSA-N 0.000 description 1
- YKYIFBPVNIHHID-CVEARBPZSA-N O=C(N[C@H]1[C@@H]2CCCC1)N2C(CC1)CCN1C1CCNCC1 Chemical compound O=C(N[C@H]1[C@@H]2CCCC1)N2C(CC1)CCN1C1CCNCC1 YKYIFBPVNIHHID-CVEARBPZSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81220906P | 2006-06-09 | 2006-06-09 | |
| US60/812,209 | 2006-06-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20090018210A true KR20090018210A (ko) | 2009-02-19 |
Family
ID=38801727
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097000417A Withdrawn KR20090018210A (ko) | 2006-06-09 | 2007-06-08 | 통증, 알쯔하이머병 및 정신분열증의 치료에 효과적인 무스카린성 수용체 효능제 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7956069B2 (https=) |
| EP (1) | EP2035411A1 (https=) |
| JP (1) | JP2009539831A (https=) |
| KR (1) | KR20090018210A (https=) |
| CN (1) | CN101501025A (https=) |
| AR (1) | AR061305A1 (https=) |
| AU (1) | AU2007256012A1 (https=) |
| BR (1) | BRPI0712331A2 (https=) |
| CA (1) | CA2654138A1 (https=) |
| EC (1) | ECSP088966A (https=) |
| IL (1) | IL195431A0 (https=) |
| MX (1) | MX2008015136A (https=) |
| NO (1) | NO20085270L (https=) |
| RU (1) | RU2008147542A (https=) |
| SA (1) | SA07280303B1 (https=) |
| TW (1) | TW200813018A (https=) |
| UY (1) | UY30397A1 (https=) |
| WO (1) | WO2007142583A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200815405A (en) * | 2006-06-09 | 2008-04-01 | Astrazeneca Ab | Novel compounds |
| US8119661B2 (en) * | 2007-09-11 | 2012-02-21 | Astrazeneca Ab | Piperidine derivatives and their use as muscarinic receptor modulators |
| UY31672A1 (es) * | 2008-02-28 | 2009-09-30 | "agonistas de receptores muscarínicos composiciones farmacéuticas métodos de tratamiento de los mismos, y procedimientos para su preparación" | |
| US20090221642A1 (en) * | 2008-03-03 | 2009-09-03 | Astrazeneca Ab | Muscarinic receptor agonists, compositions, methods of treatment thereof, and processes for preparation thereof-176 |
| US20090275574A1 (en) * | 2008-05-05 | 2009-11-05 | Astrazeneca Ab | Novel compounds-300 |
| GB0817982D0 (en) * | 2008-10-01 | 2008-11-05 | Glaxo Group Ltd | Compounds |
| EP2398320A4 (en) * | 2009-02-19 | 2012-09-19 | Univ Vanderbilt | ALLOSTERIC ANTAGONISTS OF AMIDOBIPIPERIDINECARBOXYLATE M1, ANALOGUES AND DERIVATIVES THEREOF, AND METHODS FOR THEIR MANUFACTURE AND USE |
| US20100286124A1 (en) * | 2009-04-10 | 2010-11-11 | Auspex Pharmaceuticals, Inc. | Prop-2-yn-1-amine inhibitors of monoamine oxidase type b |
| RU2013114771A (ru) * | 2010-09-03 | 2014-10-10 | Янссен Фармацевтика Нв | Диамиды азетидинила как ингибиторы моноацилглицерол липазы |
| WO2014122474A1 (en) | 2013-02-07 | 2014-08-14 | Takeda Pharmaceutical Company Limited | Piperidin-1 -yl and azepin-1 -yl carboxylates as muscarinic m4 receptor agonists |
| EP3774746A1 (en) * | 2018-04-06 | 2021-02-17 | Aquinox Pharmaceuticals (Canada) Inc. | Indene derivatives useful in treating pain and inflammation |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3066434D1 (en) | 1979-11-21 | 1984-03-08 | Kyowa Hakko Kogyo Kk | Novel piperidine derivatives, method for the preparation thereof and pharmaceutical compositions containing them |
| DE4302051A1 (de) | 1993-01-26 | 1994-07-28 | Thomae Gmbh Dr K | 5-gliedrige Heterocyclen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
| ATE216580T1 (de) | 1993-07-16 | 2002-05-15 | Merck & Co Inc | Benzoxazinon- und benzopyrimidinon- piperidinyl- verbindungen als tokolytische oxytocin-rezeptor- antagonisten |
| JP2002515008A (ja) * | 1994-10-27 | 2002-05-21 | メルク エンド カンパニー インコーポレーテッド | ムスカリン・アンタゴニスト |
| US5756508A (en) * | 1995-10-31 | 1998-05-26 | Merck & Co., Inc. | Muscarine antagonists |
| WO1997016192A1 (en) * | 1995-10-31 | 1997-05-09 | Merck & Co., Inc. | Muscarine antagonists |
| US5756497A (en) | 1996-03-01 | 1998-05-26 | Merck & Co., Inc. | Tocolytic oxytocin receptor antagonists |
| DE59711622D1 (de) | 1996-09-10 | 2004-06-17 | Boehringer Ingelheim Pharma | Abgewandelte aminosäuren, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| JPH10158192A (ja) | 1996-10-03 | 1998-06-16 | Eisai Co Ltd | 移植片対宿主疾患（ｇｖｈｄ）の治療および臓器移植時の移植片拒絶反応抑制のための医薬組成物 |
| SE9704546D0 (sv) | 1997-12-05 | 1997-12-05 | Astra Pharma Prod | Novel compounds |
| AU2307999A (en) * | 1997-12-23 | 1999-07-12 | Alcon Laboratories, Inc. | Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions |
| JP2000323278A (ja) | 1999-05-14 | 2000-11-24 | Toray Ind Inc | 発光素子 |
| ATE275141T1 (de) | 1999-10-13 | 2004-09-15 | Banyu Pharma Co Ltd | Substituierte imidazolin-derivate |
| SE9904652D0 (sv) | 1999-12-17 | 1999-12-17 | Astra Pharma Prod | Novel Compounds |
| EP1309593B1 (en) | 2000-08-14 | 2006-03-15 | Ortho-McNeil Pharmaceutical, Inc. | Substituted pyrazoles |
| JP2002302675A (ja) | 2001-04-06 | 2002-10-18 | Fuji Photo Film Co Ltd | 液晶組成物、それを用いた液晶素子およびアゾ化合物 |
| US6872733B2 (en) * | 2001-04-18 | 2005-03-29 | Euro-Celtique S.A. | Benzimidazolone compounds |
| NZ551453A (en) | 2001-04-18 | 2008-02-29 | Euro Celtique Sa | Nociceptin analogs for the treatment of pain |
| JPWO2002085890A1 (ja) * | 2001-04-20 | 2004-08-12 | 萬有製薬株式会社 | ベンズイミダゾロン誘導体 |
| ATE516030T1 (de) * | 2001-10-02 | 2011-07-15 | Acadia Pharm Inc | Benzimidazolidinon-derivate als muscarinische mittel |
| WO2004089942A2 (en) * | 2001-10-02 | 2004-10-21 | Acadia Pharmaceuticals Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| WO2003037890A2 (en) | 2001-11-01 | 2003-05-08 | Icagen, Inc. | Piperidines |
| PT1499316E (pt) | 2002-04-18 | 2008-06-30 | Schering Corp | Derivados de (1-4-piperidinil)benzimidazole úteis como antagonistas de histamina h3 |
| JP2005532361A (ja) * | 2002-06-17 | 2005-10-27 | メルク エンド カムパニー インコーポレーテッド | 高眼圧症の治療用の眼科用組成物 |
| WO2004069828A1 (ja) * | 2003-02-04 | 2004-08-19 | Mitsubishi Pharma Corporation | ピペリジン化合物およびその医薬用途 |
| CA2524221A1 (en) | 2003-04-30 | 2004-11-18 | The Institutes For Pharmaceutical Discovery, Llc | Substituted heteroaryls as inhibitors of protein tyrosine phosphatases |
| US20050250794A1 (en) | 2003-12-19 | 2005-11-10 | Andrew Napper | Methods of treating a disorder |
| US20050228023A1 (en) | 2003-12-19 | 2005-10-13 | Sri International | Agonist and antagonist ligands of the nociceptin receptor |
| AU2005249494A1 (en) * | 2004-05-28 | 2005-12-15 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
| EP1790637B1 (en) | 2004-09-13 | 2014-01-29 | Ono Pharmaceutical Co., Ltd. | Derivatives of N-4-piperidyl urea and medicaments containing them as active ingredient |
| CA2581930A1 (en) | 2004-09-27 | 2006-04-06 | Jane Trepel | Modulating mxa expression |
| WO2006038594A1 (ja) | 2004-10-04 | 2006-04-13 | Ono Pharmaceutical Co., Ltd. | Ｎ型カルシウムチャネル阻害薬 |
| WO2006130469A1 (en) | 2005-05-27 | 2006-12-07 | Oregon Health & Science University | Stimulation of neurite outgrowth by small molecules |
| TW200815351A (en) | 2006-05-02 | 2008-04-01 | Astrazeneca Ab | Novel compounds |
| TW200815405A (en) | 2006-06-09 | 2008-04-01 | Astrazeneca Ab | Novel compounds |
| US8119661B2 (en) * | 2007-09-11 | 2012-02-21 | Astrazeneca Ab | Piperidine derivatives and their use as muscarinic receptor modulators |
| UY31672A1 (es) | 2008-02-28 | 2009-09-30 | "agonistas de receptores muscarínicos composiciones farmacéuticas métodos de tratamiento de los mismos, y procedimientos para su preparación" | |
| US20090221642A1 (en) | 2008-03-03 | 2009-09-03 | Astrazeneca Ab | Muscarinic receptor agonists, compositions, methods of treatment thereof, and processes for preparation thereof-176 |
| US20090275574A1 (en) | 2008-05-05 | 2009-11-05 | Astrazeneca Ab | Novel compounds-300 |
-
2007
- 2007-05-29 TW TW096119135A patent/TW200813018A/zh unknown
- 2007-06-07 UY UY30397A patent/UY30397A1/es unknown
- 2007-06-08 AU AU2007256012A patent/AU2007256012A1/en not_active Abandoned
- 2007-06-08 RU RU2008147542/04A patent/RU2008147542A/ru not_active Application Discontinuation
- 2007-06-08 KR KR1020097000417A patent/KR20090018210A/ko not_active Withdrawn
- 2007-06-08 JP JP2009514231A patent/JP2009539831A/ja not_active Ceased
- 2007-06-08 CN CNA2007800295059A patent/CN101501025A/zh active Pending
- 2007-06-08 EP EP07748217A patent/EP2035411A1/en not_active Withdrawn
- 2007-06-08 WO PCT/SE2007/000554 patent/WO2007142583A1/en not_active Ceased
- 2007-06-08 MX MX2008015136A patent/MX2008015136A/es not_active Application Discontinuation
- 2007-06-08 US US11/760,011 patent/US7956069B2/en not_active Expired - Fee Related
- 2007-06-08 CA CA002654138A patent/CA2654138A1/en not_active Abandoned
- 2007-06-08 AR ARP070102507A patent/AR061305A1/es not_active Application Discontinuation
- 2007-06-08 BR BRPI0712331-0A patent/BRPI0712331A2/pt not_active IP Right Cessation
- 2007-06-09 SA SA7280303A patent/SA07280303B1/ar unknown
-
2008
- 2008-11-20 IL IL195431A patent/IL195431A0/en unknown
- 2008-12-12 EC EC2008008966A patent/ECSP088966A/es unknown
- 2008-12-16 NO NO20085270A patent/NO20085270L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL195431A0 (en) | 2009-08-03 |
| JP2009539831A (ja) | 2009-11-19 |
| SA07280303B1 (ar) | 2011-02-23 |
| AU2007256012A1 (en) | 2007-12-13 |
| WO2007142583A1 (en) | 2007-12-13 |
| CN101501025A (zh) | 2009-08-05 |
| TW200813018A (en) | 2008-03-16 |
| NO20085270L (no) | 2009-01-07 |
| ECSP088966A (es) | 2009-01-30 |
| CA2654138A1 (en) | 2007-12-13 |
| US20070287695A1 (en) | 2007-12-13 |
| UY30397A1 (es) | 2008-01-31 |
| EP2035411A1 (en) | 2009-03-18 |
| MX2008015136A (es) | 2008-12-10 |
| RU2008147542A (ru) | 2010-07-20 |
| BRPI0712331A2 (pt) | 2012-04-03 |
| US7956069B2 (en) | 2011-06-07 |
| AR061305A1 (es) | 2008-08-20 |
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